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The map label for this gene is ppa

Identifier: 32267347

GI number: 32267347

Start: 1770458

End: 1770958

Strand: Direct

Name: ppa

Synonym: HH1848

Alternate gene names: 32267347

Gene position: 1770458-1770958 (Clockwise)

Preceding gene: 32267346

Following gene: 32267348

Centisome position: 98.41

GC content: 35.53

Gene sequence:

>501_bases
GTGGGTGAAAATCCAAATAAAATCAATGTTATCATTGAAATCCCTTATGGTTCAAATATTAAATACGAAGTTGATAAAGA
AAGCGGTTTAGTTGTCGTAGACAGAGTGATGTATGGTGCGATGTTTTATCCTGCTAATTATGGTTTTGTCCCCAATACAC
TCGCAGATGATGGTGACCCTGTTGATGTTCTTGTGCTTAATTCTTATCCACTTCAAGCAGGAAGTATGATTGCTTCTAGG
CTTATTGGTGTGCTAATTATGGAAGATGAAAGCGGAATGGACGAAAAACTCATTGCTGTGCCTGTTTCTAAAATTGACCC
CTCATTTGAAAAGATTCAAAGCCTAGCAGATTTACCACAAATCACACTTGATAGAATCAAAAATTTCTTTGAAACTTACA
AAACACTAGAGCCAAACAAATGGGTAAAAGTTAAAGAATACAAAGACAAAACTGCTGCACAAGAGATTTTAGATAAATCA
ATCAAAGCCTACAAAGGCTAA

Upstream 100 bases:

>100_bases
ACAAATTGCACTTTCGTTTTAGTAGAATCTTTTGGTATAATCGCTTCTTTTAACATATTTTAAGTTTAAAGGAGCAGTAA
TGAATCTTTCAAAAGTATCA

Downstream 100 bases:

>100_bases
AAATACTCTTAAAATGATGTTTAAAGGAGGTTATGATGTTTCAGAAGATTCTCATTGCTAATCGTGGCGAAATTGCAGTG
CGTATTATCCGCGCTTGTAG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MGENPNKINVIIEIPYGSNIKYEVDKESGLVVVDRVMYGAMFYPANYGFVPNTLADDGDPVDVLVLNSYPLQAGSMIASR
LIGVLIMEDESGMDEKLIAVPVSKIDPSFEKIQSLADLPQITLDRIKNFFETYKTLEPNKWVKVKEYKDKTAAQEILDKS
IKAYKG

Sequences:

>Translated_166_residues
MGENPNKINVIIEIPYGSNIKYEVDKESGLVVVDRVMYGAMFYPANYGFVPNTLADDGDPVDVLVLNSYPLQAGSMIASR
LIGVLIMEDESGMDEKLIAVPVSKIDPSFEKIQSLADLPQITLDRIKNFFETYKTLEPNKWVKVKEYKDKTAAQEILDKS
IKAYKG
>Mature_165_residues
GENPNKINVIIEIPYGSNIKYEVDKESGLVVVDRVMYGAMFYPANYGFVPNTLADDGDPVDVLVLNSYPLQAGSMIASRL
IGVLIMEDESGMDEKLIAVPVSKIDPSFEKIQSLADLPQITLDRIKNFFETYKTLEPNKWVKVKEYKDKTAAQEILDKSI
KAYKG

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI29171702, Length=193, Percent_Identity=27.979274611399, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790673, Length=151, Percent_Identity=53.6423841059603, Blast_Score=161, Evalue=2e-41,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 18585; Mature: 18453

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGENPNKINVIIEIPYGSNIKYEVDKESGLVVVDRVMYGAMFYPANYGFVPNTLADDGDP
CCCCCCEEEEEEECCCCCCCEEEECCCCCEEEEHHHHHHHEECCCCCCCCCCCCCCCCCC
VDVLVLNSYPLQAGSMIASRLIGVLIMEDESGMDEKLIAVPVSKIDPSFEKIQSLADLPQ
EEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCEEEEEEHHHCCCCHHHHHHHHCCHH
ITLDRIKNFFETYKTLEPNKWVKVKEYKDKTAAQEILDKSIKAYKG
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GENPNKINVIIEIPYGSNIKYEVDKESGLVVVDRVMYGAMFYPANYGFVPNTLADDGDP
CCCCCEEEEEEECCCCCCCEEEECCCCCEEEEHHHHHHHEECCCCCCCCCCCCCCCCCC
VDVLVLNSYPLQAGSMIASRLIGVLIMEDESGMDEKLIAVPVSKIDPSFEKIQSLADLPQ
EEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCEEEEEEHHHCCCCHHHHHHHHCCHH
ITLDRIKNFFETYKTLEPNKWVKVKEYKDKTAAQEILDKSIKAYKG
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]