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The map label for this gene is frpB

Identifier: 32267346

GI number: 32267346

Start: 1768331

End: 1770379

Strand: Direct

Name: frpB

Synonym: HH1847

Alternate gene names: 32267346

Gene position: 1768331-1770379 (Clockwise)

Preceding gene: 32267345

Following gene: 32267347

Centisome position: 98.29

GC content: 36.31

Gene sequence:

>2049_bases
ATGATACTTTCTTCTTTTAAAGGTTCACCTATTTTAAGTTTTACTTTTGCATCAATTTGCAGTAGCATACTTTTTGCCGA
TGAAACACTTTCTTCCACAAAACTTTCTCCCCTTATTTCAGCAGCTCACCCTATCAGCAATGCTAATATAAGCGTTATAG
ATGATACCTTTCTTACCCATACGCAAGCAAATAATCTCCGAGATATCTTTGCCAAAGACGCCGAGATACAAGTTGGCGGT
GGTGCACAAATTGCACAAAAACTCTACGTGAGAGGCTTTGAAGATAGAATGTTTCGTGTGAGGCTTGATGGAATCACGCA
AGGAGGAAATCTCTTTCATCACCAAGGCAACCTTCTTATTGACCCATTTTTAATTAAAAGCATAGAGATAGAAAAAGGTT
TAGCAAAACCAGAAGATGGTGCAGGTGCACTTGCAGGGGGGATTAATATCATAACAAAAAATGCGTTTGATATGCTCTTA
CCAAATCGCAGTTATGGGGCACATTTTGTATTAGGAGGACAAAGCAATAAAGGTATAGACACCGCTCTTGCTACATACGG
GAAAATTACAGAGAATATAGGTTTGCTCGCAAGCTATAGCTTTGATGATGTGCCTTATTATCGTGCAGGAAATGGAGACA
AGGTCTCCTCCTCTAAAACGCGCTCGCATAATGCACTTTTTAAATTAAGTTTTCTTCCTAATGCAAATCATTCGCTTAAC
CTTAACTATCATTTTAATAATGTAAATGCCATAGCTCCCTATGGTGCTAATGTTTTGCTTAGCCAAGATCCAAAACTTTA
TGATAATACCCTCTTTTCTCACGCCATAAGCACACAATACGCTTATGTGCCAACTGATAATTTTACTTTATTGTGGAATA
CTTTTTATTCATATAAGAATCTTACACTTTCACCTATTGGAGCAGTATCTAGCACTGATCACGAAAAAGCACACGATTTA
AGTTTGCATCATCTTGGAAGCGATATAATGTTGAAACACTACTTTAGCCCTGTGCGTCATTATATAAAATATGGTTTAAA
CTATCAGCTTATCACTACCAAAGAACACAATCTTGATGGACACGATAGAGATGATAATAATCAAGGACACGAATTAGGTG
CTATTTATGGCGGATTTATTGGAGCAAATTTTAACTTTTTAGAATCTCTAAGCCTTGATGTAGGTTCGCGCTATGATGTC
TTCACTTATCGTGATAAAGTTAATACAAGGCATAATACTCAAGGATTTAGCCCTTATATCTCGCTTCTTTATGCTCCAAC
AAATGAACTTAGCTTTAAAATCACACAAAATTATAATACACGTGGAGCTATGCCTCTTGATGCTTCATTGCTCTCAAATC
CTCACGTAAAAATTACTCCATTAAAAGCAGAAGGAATGTATAACACAGAGCTTAATATGGATTATGATAATAGCCTCTTT
AGTGTGCATATAAGTCTCTATCATCAATATTTAAAAAACTTTATCAATAGCTATGTCAATTCAGGTAGCCATACAAATGG
TGCTACTCATGCTCACGGTGATTCTTTTCGTGAGAATATGGCTAGCGCTATACGAATAATTGGCTATGAAGCGAGTATGG
GGCTAGATTTTAGTTTTATTGATGTGCATATGGGTATTGCTCAAAGCTTTCCTACATATAGGCAAAAACTCATTACTGAT
ACTTTTGAGCTTGCTGCCGTAAGTGGGAGAAGTTATTTTTTGAGTGCGGGAATCCGCCCTTTTGACTTTCTACCGCAATT
TCGTATTTTATGGCTTAGTCGTTTTGTAGAGGGAATAAATTATCAAGGTTACAATATGTATTATAATGATACCGAATCTG
TAACTAAAAAAGGCTATAACACGCATAATCTTTATTTAACCTATGATGTGAAGTCTTATTTGAGTGTGCGTTTAGCATTT
TTAAATCTTACAAATCAAACTTACATAAACCCTATGAGTCCGCTTAAGGAACTCTTTTCAAAAGGAGAAGGCACACCACT
CTATGAACCCGGTTTTAGCACAAAAGCACAAATTGCACTTTCGTTTTAG

Upstream 100 bases:

>100_bases
AGTGAAAATATTTAGATTCTATCACATTTTATAAAACGTGTTGCTACATTTTATAAAATGTGATACACTTCACACTTTAT
TTTTATATAAAGGTTTTTTT

Downstream 100 bases:

>100_bases
TAGAATCTTTTGGTATAATCGCTTCTTTTAACATATTTTAAGTTTAAAGGAGCAGTAATGAATCTTTCAAAAGTATCAGT
GGGTGAAAATCCAAATAAAA

Product: iron-regulated outer membrane protein FrpB

Products: NA

Alternate protein names: Brucella heme uptake protein A [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MILSSFKGSPILSFTFASICSSILFADETLSSTKLSPLISAAHPISNANISVIDDTFLTHTQANNLRDIFAKDAEIQVGG
GAQIAQKLYVRGFEDRMFRVRLDGITQGGNLFHHQGNLLIDPFLIKSIEIEKGLAKPEDGAGALAGGINIITKNAFDMLL
PNRSYGAHFVLGGQSNKGIDTALATYGKITENIGLLASYSFDDVPYYRAGNGDKVSSSKTRSHNALFKLSFLPNANHSLN
LNYHFNNVNAIAPYGANVLLSQDPKLYDNTLFSHAISTQYAYVPTDNFTLLWNTFYSYKNLTLSPIGAVSSTDHEKAHDL
SLHHLGSDIMLKHYFSPVRHYIKYGLNYQLITTKEHNLDGHDRDDNNQGHELGAIYGGFIGANFNFLESLSLDVGSRYDV
FTYRDKVNTRHNTQGFSPYISLLYAPTNELSFKITQNYNTRGAMPLDASLLSNPHVKITPLKAEGMYNTELNMDYDNSLF
SVHISLYHQYLKNFINSYVNSGSHTNGATHAHGDSFRENMASAIRIIGYEASMGLDFSFIDVHMGIAQSFPTYRQKLITD
TFELAAVSGRSYFLSAGIRPFDFLPQFRILWLSRFVEGINYQGYNMYYNDTESVTKKGYNTHNLYLTYDVKSYLSVRLAF
LNLTNQTYINPMSPLKELFSKGEGTPLYEPGFSTKAQIALSF

Sequences:

>Translated_682_residues
MILSSFKGSPILSFTFASICSSILFADETLSSTKLSPLISAAHPISNANISVIDDTFLTHTQANNLRDIFAKDAEIQVGG
GAQIAQKLYVRGFEDRMFRVRLDGITQGGNLFHHQGNLLIDPFLIKSIEIEKGLAKPEDGAGALAGGINIITKNAFDMLL
PNRSYGAHFVLGGQSNKGIDTALATYGKITENIGLLASYSFDDVPYYRAGNGDKVSSSKTRSHNALFKLSFLPNANHSLN
LNYHFNNVNAIAPYGANVLLSQDPKLYDNTLFSHAISTQYAYVPTDNFTLLWNTFYSYKNLTLSPIGAVSSTDHEKAHDL
SLHHLGSDIMLKHYFSPVRHYIKYGLNYQLITTKEHNLDGHDRDDNNQGHELGAIYGGFIGANFNFLESLSLDVGSRYDV
FTYRDKVNTRHNTQGFSPYISLLYAPTNELSFKITQNYNTRGAMPLDASLLSNPHVKITPLKAEGMYNTELNMDYDNSLF
SVHISLYHQYLKNFINSYVNSGSHTNGATHAHGDSFRENMASAIRIIGYEASMGLDFSFIDVHMGIAQSFPTYRQKLITD
TFELAAVSGRSYFLSAGIRPFDFLPQFRILWLSRFVEGINYQGYNMYYNDTESVTKKGYNTHNLYLTYDVKSYLSVRLAF
LNLTNQTYINPMSPLKELFSKGEGTPLYEPGFSTKAQIALSF
>Mature_682_residues
MILSSFKGSPILSFTFASICSSILFADETLSSTKLSPLISAAHPISNANISVIDDTFLTHTQANNLRDIFAKDAEIQVGG
GAQIAQKLYVRGFEDRMFRVRLDGITQGGNLFHHQGNLLIDPFLIKSIEIEKGLAKPEDGAGALAGGINIITKNAFDMLL
PNRSYGAHFVLGGQSNKGIDTALATYGKITENIGLLASYSFDDVPYYRAGNGDKVSSSKTRSHNALFKLSFLPNANHSLN
LNYHFNNVNAIAPYGANVLLSQDPKLYDNTLFSHAISTQYAYVPTDNFTLLWNTFYSYKNLTLSPIGAVSSTDHEKAHDL
SLHHLGSDIMLKHYFSPVRHYIKYGLNYQLITTKEHNLDGHDRDDNNQGHELGAIYGGFIGANFNFLESLSLDVGSRYDV
FTYRDKVNTRHNTQGFSPYISLLYAPTNELSFKITQNYNTRGAMPLDASLLSNPHVKITPLKAEGMYNTELNMDYDNSLF
SVHISLYHQYLKNFINSYVNSGSHTNGATHAHGDSFRENMASAIRIIGYEASMGLDFSFIDVHMGIAQSFPTYRQKLITD
TFELAAVSGRSYFLSAGIRPFDFLPQFRILWLSRFVEGINYQGYNMYYNDTESVTKKGYNTHNLYLTYDVKSYLSVRLAF
LNLTNQTYINPMSPLKELFSKGEGTPLYEPGFSTKAQIALSF

Specific function: Heme transporter playing an important role in stationary-phase iron acquisition and required for maintenance of chronic infection in mice [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76161; Mature: 76161

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSSFKGSPILSFTFASICSSILFADETLSSTKLSPLISAAHPISNANISVIDDTFLTH
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCHHCC
TQANNLRDIFAKDAEIQVGGGAQIAQKLYVRGFEDRMFRVRLDGITQGGNLFHHQGNLLI
CCCCCHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCEEE
DPFLIKSIEIEKGLAKPEDGAGALAGGINIITKNAFDMLLPNRSYGAHFVLGGQSNKGID
CHHHHEEEEHHCCCCCCCCCCCEEECCEEEEECCCHHHHCCCCCCCEEEEEECCCCCCHH
TALATYGKITENIGLLASYSFDDVPYYRAGNGDKVSSSKTRSHNALFKLSFLPNANHSLN
HHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCEEE
LNYHFNNVNAIAPYGANVLLSQDPKLYDNTLFSHAISTQYAYVPTDNFTLLWNTFYSYKN
EEEEECCCCEECCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCEEEEEEEHHHHCC
LTLSPIGAVSSTDHEKAHDLSLHHLGSDIMLKHYFSPVRHYIKYGLNYQLITTKEHNLDG
CEECCCCCCCCCCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
HDRDDNNQGHELGAIYGGFIGANFNFLESLSLDVGSRYDVFTYRDKVNTRHNTQGFSPYI
CCCCCCCCCCEEHEEECCEECCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEE
SLLYAPTNELSFKITQNYNTRGAMPLDASLLSNPHVKITPLKAEGMYNTELNMDYDNSLF
EEEEECCCCEEEEEEECCCCCCCCCCCHHHHCCCCEEEEEEECCCEECCEECCCCCCCEE
SVHISLYHQYLKNFINSYVNSGSHTNGATHAHGDSFRENMASAIRIIGYEASMGLDFSFI
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEECCCCCCEEEE
DVHMGIAQSFPTYRQKLITDTFELAAVSGRSYFLSAGIRPFDFLPQFRILWLSRFVEGIN
EEEHHHHHCCHHHHHHHHHHHHHHEEECCCEEEEECCCCCHHHCHHHHHHHHHHHHHHCC
YQGYNMYYNDTESVTKKGYNTHNLYLTYDVKSYLSVRLAFLNLTNQTYINPMSPLKELFS
CCCCEEEECCHHHHHHCCCCCEEEEEEEEHHHHHHEEEEEEEECCCCCCCCHHHHHHHHH
KGEGTPLYEPGFSTKAQIALSF
CCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MILSSFKGSPILSFTFASICSSILFADETLSSTKLSPLISAAHPISNANISVIDDTFLTH
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCHHCC
TQANNLRDIFAKDAEIQVGGGAQIAQKLYVRGFEDRMFRVRLDGITQGGNLFHHQGNLLI
CCCCCHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCEEE
DPFLIKSIEIEKGLAKPEDGAGALAGGINIITKNAFDMLLPNRSYGAHFVLGGQSNKGID
CHHHHEEEEHHCCCCCCCCCCCEEECCEEEEECCCHHHHCCCCCCCEEEEEECCCCCCHH
TALATYGKITENIGLLASYSFDDVPYYRAGNGDKVSSSKTRSHNALFKLSFLPNANHSLN
HHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCEEE
LNYHFNNVNAIAPYGANVLLSQDPKLYDNTLFSHAISTQYAYVPTDNFTLLWNTFYSYKN
EEEEECCCCEECCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCEEEEEEEHHHHCC
LTLSPIGAVSSTDHEKAHDLSLHHLGSDIMLKHYFSPVRHYIKYGLNYQLITTKEHNLDG
CEECCCCCCCCCCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
HDRDDNNQGHELGAIYGGFIGANFNFLESLSLDVGSRYDVFTYRDKVNTRHNTQGFSPYI
CCCCCCCCCCEEHEEECCEECCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEE
SLLYAPTNELSFKITQNYNTRGAMPLDASLLSNPHVKITPLKAEGMYNTELNMDYDNSLF
EEEEECCCCEEEEEEECCCCCCCCCCCHHHHCCCCEEEEEEECCCEECCEECCCCCCCEE
SVHISLYHQYLKNFINSYVNSGSHTNGATHAHGDSFRENMASAIRIIGYEASMGLDFSFI
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEECCCCCCEEEE
DVHMGIAQSFPTYRQKLITDTFELAAVSGRSYFLSAGIRPFDFLPQFRILWLSRFVEGIN
EEEHHHHHCCHHHHHHHHHHHHHHEEECCCEEEEECCCCCHHHCHHHHHHHHHHHHHHCC
YQGYNMYYNDTESVTKKGYNTHNLYLTYDVKSYLSVRLAFLNLTNQTYINPMSPLKELFS
CCCCEEEECCHHHHHHCCCCCEEEEEEEEHHHHHHEEEEEEEECCCCCCCCHHHHHHHHH
KGEGTPLYEPGFSTKAQIALSF
CCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA