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The map label for this gene is minE

Identifier: 32266723

GI number: 32266723

Start: 1192685

End: 1192921

Strand: Direct

Name: minE

Synonym: HH1224

Alternate gene names: 32266723

Gene position: 1192685-1192921 (Clockwise)

Preceding gene: 32266722

Following gene: 32266725

Centisome position: 66.29

GC content: 36.29

Gene sequence:

>237_bases
ATGAGTCTTCTTGGTATGTTTGGACATAGCTCACAAAAAAGTGCTACTTTAGCAAGAGAGCGTCTTAAGTTGGTTTTATC
GCACGAGAGGACAGCGAATATACCCTATCTTGAAGATATGCAAAAGGAGATTCTCCAAGTTGTGCAAAAATATACGCGTT
CAAGCAAGATTGAATTTAGCACTAATAGTAATCAAAATATTAACACCCTTGAGGTAGAAATCACATTAGGAAACTAA

Upstream 100 bases:

>100_bases
AAGCTTATGTGCGGATTGCTAAGAGAATCTTAGGACAAGAAGTGCCTTTTGTTTCTTTGGAAAGTGAGGGTGTTATGGGC
ACGCTTAAAAGGATTTTTAA

Downstream 100 bases:

>100_bases
GTGATAACACGTATTTTTATTTTTTGTGGTTTTATATGTATATACCATATAAATGTGTGGGCAGATTCTATTATCACTTC
GCTACAAGATAAATCAGCAT

Product: cell division topological specificity factor MinE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 78; Mature: 77

Protein sequence:

>78_residues
MSLLGMFGHSSQKSATLARERLKLVLSHERTANIPYLEDMQKEILQVVQKYTRSSKIEFSTNSNQNINTLEVEITLGN

Sequences:

>Translated_78_residues
MSLLGMFGHSSQKSATLARERLKLVLSHERTANIPYLEDMQKEILQVVQKYTRSSKIEFSTNSNQNINTLEVEITLGN
>Mature_77_residues
SLLGMFGHSSQKSATLARERLKLVLSHERTANIPYLEDMQKEILQVVQKYTRSSKIEFSTNSNQNINTLEVEITLGN

Specific function: Prevents the cell division inhibition by proteins minC and minD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the l

COG id: COG0851

COG function: function code D; Septum formation topological specificity factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINE_HELHP (Q7VGU6)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860755.1
- GeneID:   1492912
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1224
- NMPDR:   fig|235279.1.peg.1224
- HOGENOM:   HBG449956
- OMA:   HERTANI
- ProtClustDB:   PRK00296
- BioCyc:   HHEP235279:HH_1224-MONOMER
- HAMAP:   MF_00262
- InterPro:   IPR005527
- TIGRFAMs:   TIGR01215

Pfam domain/function: PF03776 MinE

EC number: NA

Molecular weight: Translated: 8882; Mature: 8751

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLGMFGHSSQKSATLARERLKLVLSHERTANIPYLEDMQKEILQVVQKYTRSSKIEFS
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEC
TNSNQNINTLEVEITLGN
CCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
SLLGMFGHSSQKSATLARERLKLVLSHERTANIPYLEDMQKEILQVVQKYTRSSKIEFS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEC
TNSNQNINTLEVEITLGN
CCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954