Click here to switch to the map view.

The map label for this gene is ktrA

Identifier: 32266705

GI number: 32266705

Start: 1176490

End: 1177149

Strand: Direct

Name: ktrA

Synonym: HH1206

Alternate gene names: 32266705

Gene position: 1176490-1177149 (Clockwise)

Preceding gene: 32266704

Following gene: 32266709

Centisome position: 65.39

GC content: 35.61

Gene sequence:

>660_bases
ATGAAAACAAGTTATGCAGTTATTGGATTAGGGAAATTTGGGCAATATGTTGCCAAAGGGCTTATACGAAATAATGAAAA
TGTTATTGTATGTGATGATAGTGAGGAGCATATTAGAGAATTTAAGGATTTAAGTGATGAGGTTTATATCCTTGATGCGA
CAAATAAAGAAGCATTGCGTGAAGCTGGTGTTAAGGAGCTTGATGTCGTTATTATTAGCATAGGAGAAAATATAGAATCT
AGCATTTTGAGCGTGATTGCTCTCCAAGAATTGAAGAATAAATTTATTATTGCCAAAGCTGTCAATCGCTCACACGGCAT
TATTTTAAATCGTTTGGGTGTGGATTTGGTCGTGCGTCCAGAGCAAGATGCTTCAAGTCGGCTCCTTGATAAATTATTAT
GGAATCGCAACCATATTTTTAAAATCAATGAACAATTAGATTTAAGCAAAGTGCCTATTATAGAATCTGATGTAGGCAAA
AGTGTAGGCACAAAGCAATATGAGCTACAAATGCGAGAGAATGTAAAAATTATAGGCGTATATCAAAGTGGCATTTGGCA
TATTCATACCAAAAAAGCAGGGGTAAAAGAGCCCCTTGAGCAACTCATACTTGAGCAAGGAGCAGTATTGCTTTTGCTTC
AATCACATATTAATGCTTAA

Upstream 100 bases:

>100_bases
AGCTTTTTGGCTGGCATTTGTGGGCAAACGTAAGCAGAGTTATATTACTCTACAAGAGGAGCGCGTGATTATTTAGAATC
TATCAATTTTAGGAGCACGA

Downstream 100 bases:

>100_bases
GCGCAAGGATATATACAGGTTCATAAGTGAGTGTATTATTAAATCGTTGAGTGTAGTTTTTAAGCATAGTCTTTGTGAGA
TGAAAGGGTTTGTTTATACC

Product: hypothetical protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)-uptake protein ktrC; ORF4 [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKTSYAVIGLGKFGQYVAKGLIRNNENVIVCDDSEEHIREFKDLSDEVYILDATNKEALREAGVKELDVVIISIGENIES
SILSVIALQELKNKFIIAKAVNRSHGIILNRLGVDLVVRPEQDASSRLLDKLLWNRNHIFKINEQLDLSKVPIIESDVGK
SVGTKQYELQMRENVKIIGVYQSGIWHIHTKKAGVKEPLEQLILEQGAVLLLLQSHINA

Sequences:

>Translated_219_residues
MKTSYAVIGLGKFGQYVAKGLIRNNENVIVCDDSEEHIREFKDLSDEVYILDATNKEALREAGVKELDVVIISIGENIES
SILSVIALQELKNKFIIAKAVNRSHGIILNRLGVDLVVRPEQDASSRLLDKLLWNRNHIFKINEQLDLSKVPIIESDVGK
SVGTKQYELQMRENVKIIGVYQSGIWHIHTKKAGVKEPLEQLILEQGAVLLLLQSHINA
>Mature_219_residues
MKTSYAVIGLGKFGQYVAKGLIRNNENVIVCDDSEEHIREFKDLSDEVYILDATNKEALREAGVKELDVVIISIGENIES
SILSVIALQELKNKFIIAKAVNRSHGIILNRLGVDLVVRPEQDASSRLLDKLLWNRNHIFKINEQLDLSKVPIIESDVGK
SVGTKQYELQMRENVKIIGVYQSGIWHIHTKKAGVKEPLEQLILEQGAVLLLLQSHINA

Specific function: Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 24588; Mature: 24588

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSYAVIGLGKFGQYVAKGLIRNNENVIVCDDSEEHIREFKDLSDEVYILDATNKEALR
CCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCEEEEECCCHHHHH
EAGVKELDVVIISIGENIESSILSVIALQELKNKFIIAKAVNRSHGIILNRLGVDLVVRP
HCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCEEEEEC
EQDASSRLLDKLLWNRNHIFKINEQLDLSKVPIIESDVGKSVGTKQYELQMRENVKIIGV
CCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEECCCCCCCCCCHHEEEEECCCEEEEEE
YQSGIWHIHTKKAGVKEPLEQLILEQGAVLLLLQSHINA
EECCEEEEEECCCCHHHHHHHHHHHCCHHEEEEEHHCCC
>Mature Secondary Structure
MKTSYAVIGLGKFGQYVAKGLIRNNENVIVCDDSEEHIREFKDLSDEVYILDATNKEALR
CCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCEEEEECCCHHHHH
EAGVKELDVVIISIGENIESSILSVIALQELKNKFIIAKAVNRSHGIILNRLGVDLVVRP
HCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCEEEEEC
EQDASSRLLDKLLWNRNHIFKINEQLDLSKVPIIESDVGKSVGTKQYELQMRENVKIIGV
CCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEECCCCCCCCCCHHEEEEECCCEEEEEE
YQSGIWHIHTKKAGVKEPLEQLILEQGAVLLLLQSHINA
EECCEEEEEECCCCHHHHHHHHHHHCCHHEEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]