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The map label for this gene is fabZ

Identifier: 32266680

GI number: 32266680

Start: 1146482

End: 1146991

Strand: Direct

Name: fabZ

Synonym: HH1181

Alternate gene names: 32266680

Gene position: 1146482-1146991 (Clockwise)

Preceding gene: 32266679

Following gene: 32266681

Centisome position: 63.72

GC content: 34.71

Gene sequence:

>510_bases
ATGGATACAAATAAGATACAAGGGGATAAACCCATAATGAATGTGGAGAAAATTCGTCAAATTTTACCACATCGTTATCC
GATGTTACTTGTTGATAGAGTTATGGAGCTTGTGCAAAATACAAGTGATAGTGAACCAAATGGTTATATCAAAGCATATA
AAAATGTAACAATTAATGAAGAGGTATTTTTGGGGCATTTTCCAAACAAACCTATTTATCCGGGTGTAATGCAGATTGAA
GGAATGGCGCAAGCCGGCGGTCTTTTAGCATTTGTAAGTATGTTTGGTGATAATGTTGCAGAGGCAAAAAATAAAATTGT
ATATTTTATGACGATAGATAATGTTAAGTTTCGTATCCCTGTCGTCCCAGGTGATAGGCTTGTATATGAGCTCAAGGTTT
TAAAACACAAAGGAAGTATATGGCAACTTGGAGCAAATGCTTTTGTTGAGGATAAACTTGTAAGTGAAGCTGAACTTAAA
GCTATGATTACTGAAGCTAAAGAATCTTAA

Upstream 100 bases:

>100_bases
GTTTTTATTAATGCACATTTTCAAGAAAGTAGTATTTTTGCTATCACTCCATATTAAAATTTTTTGGTAGAATATCACAT
TTGTTATAAGGAGTAAGAGA

Downstream 100 bases:

>100_bases
GGAATATATATGATAGGAAAAACAAGTATTGTTAAAGAAGGCGCAAAAATAGGAAAAAATGTCCAAATTGGCGAATTTTG
CATTATTGATGAGAATACTA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MDTNKIQGDKPIMNVEKIRQILPHRYPMLLVDRVMELVQNTSDSEPNGYIKAYKNVTINEEVFLGHFPNKPIYPGVMQIE
GMAQAGGLLAFVSMFGDNVAEAKNKIVYFMTIDNVKFRIPVVPGDRLVYELKVLKHKGSIWQLGANAFVEDKLVSEAELK
AMITEAKES

Sequences:

>Translated_169_residues
MDTNKIQGDKPIMNVEKIRQILPHRYPMLLVDRVMELVQNTSDSEPNGYIKAYKNVTINEEVFLGHFPNKPIYPGVMQIE
GMAQAGGLLAFVSMFGDNVAEAKNKIVYFMTIDNVKFRIPVVPGDRLVYELKVLKHKGSIWQLGANAFVEDKLVSEAELK
AMITEAKES
>Mature_169_residues
MDTNKIQGDKPIMNVEKIRQILPHRYPMLLVDRVMELVQNTSDSEPNGYIKAYKNVTINEEVFLGHFPNKPIYPGVMQIE
GMAQAGGLLAFVSMFGDNVAEAKNKIVYFMTIDNVKFRIPVVPGDRLVYELKVLKHKGSIWQLGANAFVEDKLVSEAELK
AMITEAKES

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=157, Percent_Identity=40.7643312101911, Blast_Score=123, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_HELHP (Q7U319)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860712.1
- ProteinModelPortal:   Q7U319
- SMR:   Q7U319
- GeneID:   1492869
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1181
- NMPDR:   fig|235279.1.peg.1181
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   HHEP235279:HH_1181-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 19072; Mature: 19072

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: ACT_SITE 66-66

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTNKIQGDKPIMNVEKIRQILPHRYPMLLVDRVMELVQNTSDSEPNGYIKAYKNVTINE
CCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEECC
EVFLGHFPNKPIYPGVMQIEGMAQAGGLLAFVSMFGDNVAEAKNKIVYFMTIDNVKFRIP
EEEEEECCCCCCCCCCEEECCCHHHCHHHHHHHHHCCHHHHCCCCEEEEEEECCEEEEEE
VVPGDRLVYELKVLKHKGSIWQLGANAFVEDKLVSEAELKAMITEAKES
ECCCCCEEEEEEEHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTNKIQGDKPIMNVEKIRQILPHRYPMLLVDRVMELVQNTSDSEPNGYIKAYKNVTINE
CCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEECC
EVFLGHFPNKPIYPGVMQIEGMAQAGGLLAFVSMFGDNVAEAKNKIVYFMTIDNVKFRIP
EEEEEECCCCCCCCCCEEECCCHHHCHHHHHHHHHCCHHHHCCCCEEEEEEECCEEEEEE
VVPGDRLVYELKVLKHKGSIWQLGANAFVEDKLVSEAELKAMITEAKES
ECCCCCEEEEEEEHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954