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The map label for this gene is betT [C]

Identifier: 30995471

GI number: 30995471

Start: 1778086

End: 1780029

Strand: Reverse

Name: betT [C]

Synonym: HI1706

Alternate gene names: 30995471

Gene position: 1780029-1778086 (Counterclockwise)

Preceding gene: 16273594

Following gene: 16273591

Centisome position: 97.26

GC content: 36.27

Gene sequence:

>1944_bases
ATGGCAATGATTTTTATTGCGCCAGAGCAAACTCAAGCATTATTGAATCAAGCTAAAAGTGGTATTTTTGCTAATTTTAG
TTGGTTTTATGTACTTACTTTTTCAGTGTTTTTAGGATTTTTATTAATTTTATCAGTAAGTAGTCTTGGCAATATAAAAC
TAGGGCAAGATGAAGAAGAACCTGAATTTAGTTTCTTATCTTGGCTTGCGATGTTATTTGCCGCTGGAATGGGGGTTGGG
CTGATGTTTTTTGGCGTAGCAGAACCATTAACCCATTATCTTTCTGACATTACAGCAGGTTCTGCAGAACATAAACAACA
AGAGGCTTTACTTCATACTCTGTTCCACTGGGGAATTCACGCGTGGGCAGTATATGGCACCATTGCTTTAGCATTAGCTT
ATTTTGGGTTTCGTTATAAATTACCTTTAGCGTTGCGCTCTTGTTTTTATCCTTTATTAAAAGATCGTATTAATGGCAAA
ATCGGCGATGCAATTGATGTTATGGCGTTACTTGCCACATTATTTGGGATTATTACCACATTAGGTTTTGGTTCATCACA
GCTTGGTGCAGGGCTTGAACAAATAGGTTGGATAAGTCAGAACAGCTTTGCCTTACAAGTTGGCGTTATTGTTGTGGTGA
TGTGTTTAGCGGTGTTTTCTGCTATTTCTGGTGTTGGAAAAGGCGTGAAAATATTAAGTGAAATTAACTTAACTTTAGCA
TTTTGTTTACTTCTCTTTGTTTTAATTTCAGGCCCTACGTTATACCTTTTATCTGCATTTAGCGACAATATTGGTAATTA
TTTCAGCAATTTAGTGCAACTCAGTTTTAAAACCTATGCTTATGAACAAGAACATACTAGCTGGTTTAGCGGATGGACTG
TGCTTTATTGGGCTTGGTGGTGTTCTTGGGCTCCGTTTGTGGGTTTATTTATTGCGCGTATTTCTAAAGGGCGAACTATC
CGTGAATTTATTTTTGGCGTATTAGTTATTCCAAGTTTATTTGGTATTTTATGGTTTACTGTTTTTGGTAATACAGCAGT
ATGGCTAAATGATGGCATTGCTGCGGGCGGGCTTGGCGAATTTATTTCTTCCCCAGAAATTTTATTATTTAAATTTTTAA
ATTATCTGCCTTTACCAACAATAACAGGCTTTGTGAGCTTATTAGTGATTTTATTGTTTTTTATCACTTCAGCGGATTCA
GGTATTTATGTGTTAAATAACATTGCATCTCGTGATAAAAGTTTAGCTTCGCCTGCGTGGCAAGCCATAATGTGGGGAAC
TTTAATGTCCGTTGTTGCGATTGTGCTTATGCAATCTGGTGGACTTGCTAATTTGCAAACAATGACATTAATTGTTGCCT
TGCCTTTTGCTTTATTGATGTTGGTAATGTGTTTTAGTTTATGGAAAGGCTTAATTGCGGATAAAAAATATTTTTCTACT
AAAGTCAATCCAACTAGTATCTTCTGGAGCGGCGATAAATGGAAATCACATTTAGAGCAAATGATGAACCAAACGCAAGA
GAAAGATATTTTACGTTTCCTTAAAAATACGGCGTTACCCGCTATGCGAGAATTACGTCAAGAATTAACAGGAAAATATA
ATTTAAGTGTAGAAATCAACACATTATTTGAACAAGAAGAGCCAGCTTTGGAATTGGTAATTCATAAAGAATCAATGCGA
GATTTTATGTATGGTATTAAATCTGTTGGGCGAGAAGTGTCAGAGCAATTAATTAACGATGAAAATCTACCGCACATTCA
GCATAGTGCTACTTACGAGCCTTACACTTATTTTTTTGATGGACGAGTCGGTTACGATGTTCAATATATGGATCAAGATG
AATTGATTGCCGATATGTTGAAACAATATGAACGTTATCTAAGTTTGCTTGATGATGTGGGTCAGGAACTGATGGCACAC
GAGCAAACCGAACTAGCAGAGTAA

Upstream 100 bases:

>100_bases
CGTTAAGGGGAAAAGTTTGTCTTTATCTCAATTTATGACAAAGCGAACGTCATTTAATCCTTTGGTAATTGGCGTTACGT
TATTTTTTATATTGTTACTG

Downstream 100 bases:

>100_bases
TCGATTTAAAGGTGCAACGTGTGCCAGTTTTGTGGTTATTTAACCTGATTAATCAAAAATTGGGTTAATAGCGAAACAGG
GCGACCTGTTGCACCTTTAT

Product: high affinity choline transport protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 646

Protein sequence:

>647_residues
MAMIFIAPEQTQALLNQAKSGIFANFSWFYVLTFSVFLGFLLILSVSSLGNIKLGQDEEEPEFSFLSWLAMLFAAGMGVG
LMFFGVAEPLTHYLSDITAGSAEHKQQEALLHTLFHWGIHAWAVYGTIALALAYFGFRYKLPLALRSCFYPLLKDRINGK
IGDAIDVMALLATLFGIITTLGFGSSQLGAGLEQIGWISQNSFALQVGVIVVVMCLAVFSAISGVGKGVKILSEINLTLA
FCLLLFVLISGPTLYLLSAFSDNIGNYFSNLVQLSFKTYAYEQEHTSWFSGWTVLYWAWWCSWAPFVGLFIARISKGRTI
REFIFGVLVIPSLFGILWFTVFGNTAVWLNDGIAAGGLGEFISSPEILLFKFLNYLPLPTITGFVSLLVILLFFITSADS
GIYVLNNIASRDKSLASPAWQAIMWGTLMSVVAIVLMQSGGLANLQTMTLIVALPFALLMLVMCFSLWKGLIADKKYFST
KVNPTSIFWSGDKWKSHLEQMMNQTQEKDILRFLKNTALPAMRELRQELTGKYNLSVEINTLFEQEEPALELVIHKESMR
DFMYGIKSVGREVSEQLINDENLPHIQHSATYEPYTYFFDGRVGYDVQYMDQDELIADMLKQYERYLSLLDDVGQELMAH
EQTELAE

Sequences:

>Translated_647_residues
MAMIFIAPEQTQALLNQAKSGIFANFSWFYVLTFSVFLGFLLILSVSSLGNIKLGQDEEEPEFSFLSWLAMLFAAGMGVG
LMFFGVAEPLTHYLSDITAGSAEHKQQEALLHTLFHWGIHAWAVYGTIALALAYFGFRYKLPLALRSCFYPLLKDRINGK
IGDAIDVMALLATLFGIITTLGFGSSQLGAGLEQIGWISQNSFALQVGVIVVVMCLAVFSAISGVGKGVKILSEINLTLA
FCLLLFVLISGPTLYLLSAFSDNIGNYFSNLVQLSFKTYAYEQEHTSWFSGWTVLYWAWWCSWAPFVGLFIARISKGRTI
REFIFGVLVIPSLFGILWFTVFGNTAVWLNDGIAAGGLGEFISSPEILLFKFLNYLPLPTITGFVSLLVILLFFITSADS
GIYVLNNIASRDKSLASPAWQAIMWGTLMSVVAIVLMQSGGLANLQTMTLIVALPFALLMLVMCFSLWKGLIADKKYFST
KVNPTSIFWSGDKWKSHLEQMMNQTQEKDILRFLKNTALPAMRELRQELTGKYNLSVEINTLFEQEEPALELVIHKESMR
DFMYGIKSVGREVSEQLINDENLPHIQHSATYEPYTYFFDGRVGYDVQYMDQDELIADMLKQYERYLSLLDDVGQELMAH
EQTELAE
>Mature_646_residues
AMIFIAPEQTQALLNQAKSGIFANFSWFYVLTFSVFLGFLLILSVSSLGNIKLGQDEEEPEFSFLSWLAMLFAAGMGVGL
MFFGVAEPLTHYLSDITAGSAEHKQQEALLHTLFHWGIHAWAVYGTIALALAYFGFRYKLPLALRSCFYPLLKDRINGKI
GDAIDVMALLATLFGIITTLGFGSSQLGAGLEQIGWISQNSFALQVGVIVVVMCLAVFSAISGVGKGVKILSEINLTLAF
CLLLFVLISGPTLYLLSAFSDNIGNYFSNLVQLSFKTYAYEQEHTSWFSGWTVLYWAWWCSWAPFVGLFIARISKGRTIR
EFIFGVLVIPSLFGILWFTVFGNTAVWLNDGIAAGGLGEFISSPEILLFKFLNYLPLPTITGFVSLLVILLFFITSADSG
IYVLNNIASRDKSLASPAWQAIMWGTLMSVVAIVLMQSGGLANLQTMTLIVALPFALLMLVMCFSLWKGLIADKKYFSTK
VNPTSIFWSGDKWKSHLEQMMNQTQEKDILRFLKNTALPAMRELRQELTGKYNLSVEINTLFEQEEPALELVIHKESMRD
FMYGIKSVGREVSEQLINDENLPHIQHSATYEPYTYFFDGRVGYDVQYMDQDELIADMLKQYERYLSLLDDVGQELMAHE
QTELAE

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family

Homologues:

Organism=Escherichia coli, GI1786506, Length=618, Percent_Identity=36.4077669902913, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1788102, Length=434, Percent_Identity=29.2626728110599, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1786224, Length=429, Percent_Identity=30.0699300699301, Blast_Score=149, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1706_HAEIN (P45335)

Other databases:

- EMBL:   L42023
- PIR:   D64137
- RefSeq:   NP_439848.2
- ProteinModelPortal:   P45335
- GeneID:   950523
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1706
- NMPDR:   fig|71421.1.peg.1619
- TIGR:   HI_1706
- HOGENOM:   HBG682943
- OMA:   FISSPEI
- ProtClustDB:   CLSK870617
- BioCyc:   HINF71421:HI_1706-MONOMER
- InterPro:   IPR000060
- InterPro:   IPR018093
- TIGRFAMs:   TIGR00842

Pfam domain/function: PF02028 BCCT

EC number: NA

Molecular weight: Translated: 72515; Mature: 72384

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xee394e4)-; HASH(0xe4f8fb0)-; HASH(0xe642128)-; HASH(0xeeaa5f8)-; HASH(0xeed75a0)-; HASH(0xeb9a00c)-; HASH(0xea4b9e8)-; HASH(0xf07c258)-; HASH(0xdf14340)-; HASH(0xee9b2fc)-; HASH(0xecd3fd4)-; HASH(0xc399464)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMIFIAPEQTQALLNQAKSGIFANFSWFYVLTFSVFLGFLLILSVSSLGNIKLGQDEEE
CEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PEFSFLSWLAMLFAAGMGVGLMFFGVAEPLTHYLSDITAGSAEHKQQEALLHTLFHWGIH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AWAVYGTIALALAYFGFRYKLPLALRSCFYPLLKDRINGKIGDAIDVMALLATLFGIITT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LGFGSSQLGAGLEQIGWISQNSFALQVGVIVVVMCLAVFSAISGVGKGVKILSEINLTLA
HCCCCHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FCLLLFVLISGPTLYLLSAFSDNIGNYFSNLVQLSFKTYAYEQEHTSWFSGWTVLYWAWW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
CSWAPFVGLFIARISKGRTIREFIFGVLVIPSLFGILWFTVFGNTAVWLNDGIAAGGLGE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHH
FISSPEILLFKFLNYLPLPTITGFVSLLVILLFFITSADSGIYVLNNIASRDKSLASPAW
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
QAIMWGTLMSVVAIVLMQSGGLANLQTMTLIVALPFALLMLVMCFSLWKGLIADKKYFST
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
KVNPTSIFWSGDKWKSHLEQMMNQTQEKDILRFLKNTALPAMRELRQELTGKYNLSVEIN
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEE
TLFEQEEPALELVIHKESMRDFMYGIKSVGREVSEQLINDENLPHIQHSATYEPYTYFFD
EHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
GRVGYDVQYMDQDELIADMLKQYERYLSLLDDVGQELMAHEQTELAE
CEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
AMIFIAPEQTQALLNQAKSGIFANFSWFYVLTFSVFLGFLLILSVSSLGNIKLGQDEEE
EEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC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CEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800