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The map label for this gene is ygiY

Identifier: 16273594

GI number: 16273594

Start: 1780390

End: 1781745

Strand: Reverse

Name: ygiY

Synonym: HI1707

Alternate gene names: 16273594

Gene position: 1781745-1780390 (Counterclockwise)

Preceding gene: 16273595

Following gene: 30995471

Centisome position: 97.36

GC content: 37.32

Gene sequence:

>1356_bases
ATGAAAAATAGAAGCCTTACGTTGCGTCTTATTTCTGTGCTTTGTTTAACCGCACTTTTTGTTTGGCTGGGTTCTACGCT
TGTGGCTTGGTGGCAAGTTCGCCACGATGTGAATAAAGTTTTTGATGCACAACAAGTTCTCTTTGCTGAACGGCTCGCAA
ATTCAGATTTAAGTACTATTTTGTTGGAATCTAGCACAACGCTAAATAAAAATTCACAGTCGGTATTAAAAAAAAGTTAT
GACGATGATGCCTTAGCCTTTGCTATTTTTTCTAAAACTGGGAAACTTTTATTCAGTGATGGACGAAATGGAAAAGATTT
TATTTTTAATTATAAAACGGGGTTTTATAATGCGAATATTTATGATGATGACGATAAATGGCGAATTTTTTGGCGTATGG
CAGCTAATGGAGAATTAGTTATCGCAGTAGGGCAAGAATTAGATTACCGTGAAGATTTAATTGAAGAAATGATTTTGGGG
CAAATGTGGATTTGGTTTGCCAGTTTGCCTATTTTGATCATTGTTTTAGGATGGTTGATTCATAAAGAACTTCGACCGAT
TAAACGTTTAAGCCAAGAAGTACAAACGAGAAAATCTGGCGATGTGTCATTGCTGAATACGGAGGGGCTACCCGTTGAGA
TTTTACCCTTAGTAAAAAATTTAAATCAATTTTTTGACCGCACTTCAGCTATGTTGCAACGCGAACGCCGTTTTACTTCT
GATGCAGCTCACGAATTGCGTAGTCCATTGGCGGCATTGCGTATTCAAATTGAAGTTGCGCAACTAGCTGGCGATGATGT
AGCGTTACGAGAACAAGCACTTTTACATTTAACGCAAGGCATTGATCGGGCTTCGCAATTGATTGAACAATTATTAACGC
TTTCCCGCTTGGATAATTTGCAAGCCTTAGAAACACTACAGCTGCTTGATTGGGAAGCTATTGTTCAATCATTAATTTCT
GAGCGTTATTTTGTGGCAGAAAAACGTAAAATTACCTTGGTTTTTGAGAAAGAATCTGAACCAAAGCAAAAACAAGGGCA
ATCAATTTTAGTTTCATTGATGCTTAGAAATTTACTCGACAATGCTATTAAATATTGTCCTGAAGATACAATCGTTTCAG
TAAAAATTTCATCCTCACAGATTATTATTGAGGACAATGGTGGTGGCGTTGAACCTGAAGATTTGAAAAAACTTGGACAG
CGTTTTTATCGTCCAGCTGGGCAAAATGAAAAGGGAAGTGGCTTGGGACTTTCTATTGTTATGCGAATTGCGGAATTACA
CGGATTTAAAGTGCGGTTAGAAAATGTTGTAAAAGAGGGGAGAAGAATTGGCTTAAAAGCAATAATATCCTTGTAG

Upstream 100 bases:

>100_bases
GCGCATTGGATGTGCATATTTATAATTTACGCCAAAAATTGGGGAAGCAATTTATTCGAACAGTACACGGTGTTGGATAT
GCTTTGGGACAAGTTGAAAA

Downstream 100 bases:

>100_bases
AAATGGCTTTAAAATAAATGATATTTGTGCGGTAAATTATTTTGTAAATTTTACCGCATTTTTTAGTTTAGCTTTCACTA
ATTTGAAATAATGACTGTAT

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKNRSLTLRLISVLCLTALFVWLGSTLVAWWQVRHDVNKVFDAQQVLFAERLANSDLSTILLESSTTLNKNSQSVLKKSY
DDDALAFAIFSKTGKLLFSDGRNGKDFIFNYKTGFYNANIYDDDDKWRIFWRMAANGELVIAVGQELDYREDLIEEMILG
QMWIWFASLPILIIVLGWLIHKELRPIKRLSQEVQTRKSGDVSLLNTEGLPVEILPLVKNLNQFFDRTSAMLQRERRFTS
DAAHELRSPLAALRIQIEVAQLAGDDVALREQALLHLTQGIDRASQLIEQLLTLSRLDNLQALETLQLLDWEAIVQSLIS
ERYFVAEKRKITLVFEKESEPKQKQGQSILVSLMLRNLLDNAIKYCPEDTIVSVKISSSQIIIEDNGGGVEPEDLKKLGQ
RFYRPAGQNEKGSGLGLSIVMRIAELHGFKVRLENVVKEGRRIGLKAIISL

Sequences:

>Translated_451_residues
MKNRSLTLRLISVLCLTALFVWLGSTLVAWWQVRHDVNKVFDAQQVLFAERLANSDLSTILLESSTTLNKNSQSVLKKSY
DDDALAFAIFSKTGKLLFSDGRNGKDFIFNYKTGFYNANIYDDDDKWRIFWRMAANGELVIAVGQELDYREDLIEEMILG
QMWIWFASLPILIIVLGWLIHKELRPIKRLSQEVQTRKSGDVSLLNTEGLPVEILPLVKNLNQFFDRTSAMLQRERRFTS
DAAHELRSPLAALRIQIEVAQLAGDDVALREQALLHLTQGIDRASQLIEQLLTLSRLDNLQALETLQLLDWEAIVQSLIS
ERYFVAEKRKITLVFEKESEPKQKQGQSILVSLMLRNLLDNAIKYCPEDTIVSVKISSSQIIIEDNGGGVEPEDLKKLGQ
RFYRPAGQNEKGSGLGLSIVMRIAELHGFKVRLENVVKEGRRIGLKAIISL
>Mature_451_residues
MKNRSLTLRLISVLCLTALFVWLGSTLVAWWQVRHDVNKVFDAQQVLFAERLANSDLSTILLESSTTLNKNSQSVLKKSY
DDDALAFAIFSKTGKLLFSDGRNGKDFIFNYKTGFYNANIYDDDDKWRIFWRMAANGELVIAVGQELDYREDLIEEMILG
QMWIWFASLPILIIVLGWLIHKELRPIKRLSQEVQTRKSGDVSLLNTEGLPVEILPLVKNLNQFFDRTSAMLQRERRFTS
DAAHELRSPLAALRIQIEVAQLAGDDVALREQALLHLTQGIDRASQLIEQLLTLSRLDNLQALETLQLLDWEAIVQSLIS
ERYFVAEKRKITLVFEKESEPKQKQGQSILVSLMLRNLLDNAIKYCPEDTIVSVKISSSQIIIEDNGGGVEPEDLKKLGQ
RFYRPAGQNEKGSGLGLSIVMRIAELHGFKVRLENVVKEGRRIGLKAIISL

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1789403, Length=437, Percent_Identity=44.1647597254005, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1786783, Length=297, Percent_Identity=29.2929292929293, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790551, Length=282, Percent_Identity=29.0780141843972, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788279, Length=323, Percent_Identity=29.1021671826625, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=274, Percent_Identity=29.1970802919708, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787894, Length=341, Percent_Identity=28.4457478005865, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788393, Length=262, Percent_Identity=29.0076335877863, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=204, Percent_Identity=31.8627450980392, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787374, Length=283, Percent_Identity=28.2685512367491, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=27.3858921161826, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QSEC_HAEIN (P45336)

Other databases:

- EMBL:   L42023
- PIR:   E64137
- RefSeq:   NP_439849.1
- ProteinModelPortal:   P45336
- SMR:   P45336
- GeneID:   950868
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1707
- NMPDR:   fig|71421.1.peg.1620
- TIGR:   HI_1707
- HOGENOM:   HBG334875
- OMA:   HRNDELE
- ProtClustDB:   CLSK870015
- BioCyc:   HINF71421:HI_1707-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 51272; Mature: 51272

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf07c2d0)-; HASH(0xe30bd14)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRSLTLRLISVLCLTALFVWLGSTLVAWWQVRHDVNKVFDAQQVLFAERLANSDLSTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEE
LLESSTTLNKNSQSVLKKSYDDDALAFAIFSKTGKLLFSDGRNGKDFIFNYKTGFYNANI
EEECCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCEEECCE
YDDDDKWRIFWRMAANGELVIAVGQELDYREDLIEEMILGQMWIWFASLPILIIVLGWLI
ECCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKELRPIKRLSQEVQTRKSGDVSLLNTEGLPVEILPLVKNLNQFFDRTSAMLQRERRFTS
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAHELRSPLAALRIQIEVAQLAGDDVALREQALLHLTQGIDRASQLIEQLLTLSRLDNL
HHHHHHHCHHHHHHEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QALETLQLLDWEAIVQSLISERYFVAEKRKITLVFEKESEPKQKQGQSILVSLMLRNLLD
HHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
NAIKYCPEDTIVSVKISSSQIIIEDNGGGVEPEDLKKLGQRFYRPAGQNEKGSGLGLSIV
HHHHHCCCCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
MRIAELHGFKVRLENVVKEGRRIGLKAIISL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MKNRSLTLRLISVLCLTALFVWLGSTLVAWWQVRHDVNKVFDAQQVLFAERLANSDLSTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEE
LLESSTTLNKNSQSVLKKSYDDDALAFAIFSKTGKLLFSDGRNGKDFIFNYKTGFYNANI
EEECCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCEEECCE
YDDDDKWRIFWRMAANGELVIAVGQELDYREDLIEEMILGQMWIWFASLPILIIVLGWLI
ECCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKELRPIKRLSQEVQTRKSGDVSLLNTEGLPVEILPLVKNLNQFFDRTSAMLQRERRFTS
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAHELRSPLAALRIQIEVAQLAGDDVALREQALLHLTQGIDRASQLIEQLLTLSRLDNL
HHHHHHHCHHHHHHEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QALETLQLLDWEAIVQSLISERYFVAEKRKITLVFEKESEPKQKQGQSILVSLMLRNLLD
HHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
NAIKYCPEDTIVSVKISSSQIIIEDNGGGVEPEDLKKLGQRFYRPAGQNEKGSGLGLSIV
HHHHHCCCCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
MRIAELHGFKVRLENVVKEGRRIGLKAIISL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023