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The map label for this gene is yfcB

Identifier: 30063756

GI number: 30063756

Start: 2435088

End: 2436353

Strand: Reverse

Name: yfcB

Synonym: S2542

Alternate gene names: 30063756

Gene position: 2436353-2435088 (Counterclockwise)

Preceding gene: 30063758

Following gene: 30063755

Centisome position: 52.97

GC content: 51.18

Gene sequence:

>1266_bases
ATGGCTGGCATCAGCCTGCTCCTGGATCAAGCGTTTCACCGGCACTTCGCTGATTTTTTTACGCTGCGGTCGGTGGACAA
TCGTGTCCTGCTTAATCTTGCGAGTCCCCGCCATCAACTGGCGAAACAGAGCCTGGTCCTCCTCGCTAAGTGTTGTTTTC
TTTTTCATTTATCTGTCTCTATTTCTAATTTTCCTACAGTTTACCCGACTCGTAGCACAATCGATCGTTTTAAACGTATT
TTTCCTCACTCACCGCGCGTGAATGCTGATTTATCGTCATCTTCATGGCAAACTAGCCGCCGAAATTATTGCGATCATGC
CCTGGAGGAATACGTGGATAAAATTTTCGTTGATGAAGCAGTAAATGAGCTGCAAACCATTCAGGACATATTGCGCTGGT
CGGTAAGCCGCTTCAGCGCGGCAAATATCTGGTACGGTCACGGCACCGATAACCCGTGGGATGAAGCCGTACAGCTGGTG
TTACCATCGCTCTACCTGCCGCTGGATATCCCGGAAGATATGCGCACCGCGCGTCTGACCTCCAGCGAAAAACACCGTAT
TGTTGAACGCGTGATCCGCCGCGTCAACGAGCGCATTCCGGTGGCTTACCTGACCAACAAAGCCTGGTTCTGCGGTCATG
AATTTTACGTCGATGAACGCGTGCTGGTGCCGCGCTCGCCGATTGGTGAACTGATCAACAATAAATTTGCCGGACTCATC
AGCAAGCAACCGCAGCATATTTTAGATATGTGTACCGGTAGCGGCTGCATCGCCATTGCCTGTGCTTATGCCTTCCCGGA
AGCGGAAGTCGACGCGGTAGATATCTCTCCCGACGCGCTGGCGGTTGCCGAACAGAACATCGAAGAACACGGTCTGATCC
ACAACGTCATTCCGATTCGTTCCGATCTGTTCCGTGATTTGCCGAAAGTGCAATACGATCTGATTGTCACTAACCCGCCG
TATGTCGACGCGGAAGATATGTCCGACCTGCCAAACGAATACCGTCACGAGCCGGAACTGGGCCTGGCATCTGGCACCGA
CGGCCTGAAACTGACGCGTCGCATTCTCGGTAACGCGGCAGATTACCTTGCTGATGATGGCGTGTTGATTTGTGAAGTGG
GCAACAGCATGGTACATCTTATGGAACAATATCCCGATGTTCCGTTCACCTGGCTGGAGTTTGATAACGGCGGCGATGGT
GTGTTTATGCTCACTAAAGAGCAGCTTATTGCCGCACGAGAACATTTCGCGATTTATAAAGATTAA

Upstream 100 bases:

>100_bases
CGCGGCGCAGTTTCTTCGCCTCAAAATGGCTGACATCCGGGCGAACATATTTCACCGGACCTTCGGTATTTAATAACGGC
TGAAACTCATCGGAGAAATA

Downstream 100 bases:

>100_bases
GTAAACACGCAAACACAACAATAACGGAGCCGTGATGGCTGGAAACACAATTGGACAACTCTTTCGCGTAACCACCTTCG
GCGAATCGCACGGGCTGGCG

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAGISLLLDQAFHRHFADFFTLRSVDNRVLLNLASPRHQLAKQSLVLLAKCCFLFHLSVSISNFPTVYPTRSTIDRFKRI
FPHSPRVNADLSSSSWQTSRRNYCDHALEEYVDKIFVDEAVNELQTIQDILRWSVSRFSAANIWYGHGTDNPWDEAVQLV
LPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNKFAGLI
SKQPQHILDMCTGSGCIAIACAYAFPEAEVDAVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPP
YVDAEDMSDLPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDVPFTWLEFDNGGDG
VFMLTKEQLIAAREHFAIYKD

Sequences:

>Translated_421_residues
MAGISLLLDQAFHRHFADFFTLRSVDNRVLLNLASPRHQLAKQSLVLLAKCCFLFHLSVSISNFPTVYPTRSTIDRFKRI
FPHSPRVNADLSSSSWQTSRRNYCDHALEEYVDKIFVDEAVNELQTIQDILRWSVSRFSAANIWYGHGTDNPWDEAVQLV
LPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNKFAGLI
SKQPQHILDMCTGSGCIAIACAYAFPEAEVDAVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPP
YVDAEDMSDLPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDVPFTWLEFDNGGDG
VFMLTKEQLIAAREHFAIYKD
>Mature_420_residues
AGISLLLDQAFHRHFADFFTLRSVDNRVLLNLASPRHQLAKQSLVLLAKCCFLFHLSVSISNFPTVYPTRSTIDRFKRIF
PHSPRVNADLSSSSWQTSRRNYCDHALEEYVDKIFVDEAVNELQTIQDILRWSVSRFSAANIWYGHGTDNPWDEAVQLVL
PSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNKFAGLIS
KQPQHILDMCTGSGCIAIACAYAFPEAEVDAVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPY
VDAEDMSDLPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGV
FMLTKEQLIAAREHFAIYKD

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=231, Percent_Identity=29.004329004329, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87082085, Length=310, Percent_Identity=99.0322580645161, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1787463, Length=194, Percent_Identity=32.4742268041237, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24582226, Length=194, Percent_Identity=26.2886597938144, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 47789; Mature: 47658

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGISLLLDQAFHRHFADFFTLRSVDNRVLLNLASPRHQLAKQSLVLLAKCCFLFHLSVS
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ISNFPTVYPTRSTIDRFKRIFPHSPRVNADLSSSSWQTSRRNYCDHALEEYVDKIFVDEA
HCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNELQTIQDILRWSVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIPEDMRTARLT
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
SSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNKFAGLI
CHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCEEEECCEEECCCCHHHHHHHHHHHHHH
SKQPQHILDMCTGSGCIAIACAYAFPEAEVDAVDISPDALAVAEQNIEEHGLIHNVIPIR
CCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCHHHCCCHHHHHHHH
SDLFRDLPKVQYDLIVTNPPYVDAEDMSDLPNEYRHEPELGLASGTDGLKLTRRILGNAA
HHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCHH
DYLADDGVLICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKEQLIAAREHFAIYK
HHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHCEEC
D
C
>Mature Secondary Structure 
AGISLLLDQAFHRHFADFFTLRSVDNRVLLNLASPRHQLAKQSLVLLAKCCFLFHLSVS
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ISNFPTVYPTRSTIDRFKRIFPHSPRVNADLSSSSWQTSRRNYCDHALEEYVDKIFVDEA
HCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNELQTIQDILRWSVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIPEDMRTARLT
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
SSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNKFAGLI
CHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCEEEECCEEECCCCHHHHHHHHHHHHHH
SKQPQHILDMCTGSGCIAIACAYAFPEAEVDAVDISPDALAVAEQNIEEHGLIHNVIPIR
CCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCHHHCCCHHHHHHHH
SDLFRDLPKVQYDLIVTNPPYVDAEDMSDLPNEYRHEPELGLASGTDGLKLTRRILGNAA
HHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCHH
DYLADDGVLICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKEQLIAAREHFAIYK
HHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHCEEC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2182772; 2969724; 7984428 [H]