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The map label for this gene is pgk [H]

Identifier: 294514842

GI number: 294514842

Start: 2832249

End: 2833427

Strand: Reverse

Name: pgk [H]

Synonym: NA

Alternate gene names: 294514842

Gene position: 2833427-2832249 (Counterclockwise)

Preceding gene: 218710595

Following gene: 218710594

Centisome position: 85.88

GC content: 45.8

Gene sequence:

>1179_bases
TTGAGAGGACAAATCATGTCTGTGATCAAGATGACTGACCTGGAACTTGCAGGTAAACGCGTATTCATCCGTGCTGACCT
AAACGTACCAGTAAAAGACGGTAAAGTAACTTCAGATGCACGTATCCTTGCATCTCTACCAACTATCAAACTTTGCCTAG
AAGCTGGCGCAAAAGTTATGGTTACTTCTCACCTTGGTCGTCCTACTGAAGGCGAGTACAACGAAGAGTTCTCTCTAGCT
CCTGTAGTTAACTACCTAAACGACGCACTAGACTGTGACGTTAAACTAGCGAAAGATTACGTAAATGGTCTTGAGCTAAA
CGCTGGTGAACTAACTGTTCTTGAAAACGTTCGCTTTAACAAAGGCGAGAAGAAGAACGAAGAAGCTCTTTCTAAGCAAT
ACGCTGCACTATGTGACATCTTCGTAATGGATGCATTCGGTACAGCTCACCGTGCTCAAGCGTCTACACACGGCGTTGGT
ACTTACGCTCCTGTAGCATGTGCTGGTCCTCTTCTAGCTGCTGAGCTTGAAGCTCTTGGTAAAGCAATGGACAACCCAGC
TCGCCCACTAGTGGCTATCGTTGGTGGTTCTAAAGTTTCTACTAAACTAACCGTTCTAGAATCTCTTTCTAAAATCGCTG
ACCAACTTGTTGTTGGTGGTGGTATCGCGAACACGTTCATCGCTGCTGAAGGCCACAACGTAGGTAAGTCTCTATACGAA
GCTGACCTAGTTGAAACAGCTCAGAAGCTAATGAAAGAGTGTGCTATCCCAGTAGCGACTGACGTTGCATGTGCTAAAGC
ATTCGACGAAAACGCAGAAGCTGAAATCAAGCACGTTTCTGAAGTTCAAGACGACGACATGATCTTCGACCTTGGTCCAG
ATTCAACTGCAGCTCTAGCTGAAATCATCGGCAACGCGAAAACTATTCTTTGGAACGGCCCTGTAGGTGTATTCGAATTC
AAGAACTTTGAAGCGGGTACAGCTGGTATTTCTAAAGCAATCGCTGATTCTGAAGGTTTCTCAGTAGCGGGCGGTGGTGA
CACGCTAGCAGCTATCGACAAGTTCGGTATCAAAGCAGATGTTTCTTACATCTCTACTGGTGGCGGTGCTTTCCTTGAGT
TTGTTGAAGGCAAAGTACTTCCTGCAGTAGCTATGCTTGAAGAGCGTGCTAAAGCGTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: 3-phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:
NA

Sequences:

>Translated_392_residues
MRGQIMSVIKMTDLELAGKRVFIRADLNVPVKDGKVTSDARILASLPTIKLCLEAGAKVMVTSHLGRPTEGEYNEEFSLA
PVVNYLNDALDCDVKLAKDYVNGLELNAGELTVLENVRFNKGEKKNEEALSKQYAALCDIFVMDAFGTAHRAQASTHGVG
TYAPVACAGPLLAAELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAEGHNVGKSLYE
ADLVETAQKLMKECAIPVATDVACAKAFDENAEAEIKHVSEVQDDDMIFDLGPDSTAALAEIIGNAKTILWNGPVGVFEF
KNFEAGTAGISKAIADSEGFSVAGGGDTLAAIDKFGIKADVSYISTGGGAFLEFVEGKVLPAVAMLEERAKA
>Mature_392_residues
MRGQIMSVIKMTDLELAGKRVFIRADLNVPVKDGKVTSDARILASLPTIKLCLEAGAKVMVTSHLGRPTEGEYNEEFSLA
PVVNYLNDALDCDVKLAKDYVNGLELNAGELTVLENVRFNKGEKKNEEALSKQYAALCDIFVMDAFGTAHRAQASTHGVG
TYAPVACAGPLLAAELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAEGHNVGKSLYE
ADLVETAQKLMKECAIPVATDVACAKAFDENAEAEIKHVSEVQDDDMIFDLGPDSTAALAEIIGNAKTILWNGPVGVFEF
KNFEAGTAGISKAIADSEGFSVAGGGDTLAAIDKFGIKADVSYISTGGGAFLEFVEGKVLPAVAMLEERAKA

Specific function: Second phase of glycolysis; second step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=413, Percent_Identity=38.2566585956416, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI4505763, Length=413, Percent_Identity=38.498789346247, Blast_Score=248, Evalue=7e-66,
Organism=Escherichia coli, GI1789294, Length=386, Percent_Identity=76.6839378238342, Blast_Score=600, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17508823, Length=418, Percent_Identity=39.9521531100478, Blast_Score=263, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6319857, Length=424, Percent_Identity=39.3867924528302, Blast_Score=265, Evalue=9e-72,
Organism=Drosophila melanogaster, GI17136394, Length=415, Percent_Identity=41.2048192771084, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI24581203, Length=422, Percent_Identity=38.6255924170616, Blast_Score=242, Evalue=3e-64,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 41201; Mature: 41201

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGQIMSVIKMTDLELAGKRVFIRADLNVPVKDGKVTSDARILASLPTIKLCLEAGAKVM
CCCHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHHCCCEEE
VTSHLGRPTEGEYNEEFSLAPVVNYLNDALDCDVKLAKDYVNGLELNAGELTVLENVRFN
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCCC
KGEKKNEEALSKQYAALCDIFVMDAFGTAHRAQASTHGVGTYAPVACAGPLLAAELEALG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHH
KAMDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAEGHNVGKSLYE
HHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCHHHHEEEECCCHHHHHHHH
ADLVETAQKLMKECAIPVATDVACAKAFDENAEAEIKHVSEVQDDDMIFDLGPDSTAALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHH
EIIGNAKTILWNGPVGVFEFKNFEAGTAGISKAIADSEGFSVAGGGDTLAAIDKFGIKAD
HHHCCCEEEEECCCCCEEEECCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCEEE
VSYISTGGGAFLEFVEGKVLPAVAMLEERAKA
CCEEECCCHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGQIMSVIKMTDLELAGKRVFIRADLNVPVKDGKVTSDARILASLPTIKLCLEAGAKVM
CCCHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHHCCCEEE
VTSHLGRPTEGEYNEEFSLAPVVNYLNDALDCDVKLAKDYVNGLELNAGELTVLENVRFN
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCCC
KGEKKNEEALSKQYAALCDIFVMDAFGTAHRAQASTHGVGTYAPVACAGPLLAAELEALG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHH
KAMDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAEGHNVGKSLYE
HHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCHHHHEEEECCCHHHHHHHH
ADLVETAQKLMKECAIPVATDVACAKAFDENAEAEIKHVSEVQDDDMIFDLGPDSTAALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHH
EIIGNAKTILWNGPVGVFEFKNFEAGTAGISKAIADSEGFSVAGGGDTLAAIDKFGIKAD
HHHCCCEEEEECCCCCEEEECCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCEEE
VSYISTGGGAFLEFVEGKVLPAVAMLEERAKA
CCEEECCCHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA