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The map label for this gene is corA [H]

Identifier: 29350087

GI number: 29350087

Start: 6134472

End: 6135524

Strand: Reverse

Name: corA [H]

Synonym: BT_4679

Alternate gene names: 29350087

Gene position: 6135524-6134472 (Counterclockwise)

Preceding gene: 29350088

Following gene: 29350086

Centisome position: 98.01

GC content: 41.22

Gene sequence:

>1053_bases
ATGAAGAATAATCTGTTAAGCGAAAAGCTTATTTACACAGGGGACAGCCTTACCCCCACCCATTTACATCTCTGCACATA
CAATGCAACCGAGATGCAGGAAAGTTCCGGTGACACCTTCCAAAGCGTCAAAGAAACATTGGATAACGAACGAATCAACT
GGCTGCAGGTACACGGGCTGAAAGATACGGAAACCATCCGTGAGATTTGCAGTCATTTTGAAATAGACTTCCTCGTTTTA
CAAGACATATTAAATGCCGACCACCCGACGAAAATAGAAGAGCATGACAAATATATTGTCCTGATCCTGAAAATATTCTA
TCCCAATGAGCATAAAGAGGATGATGACCTCGACGGATTGCTCCAACAACAAGTCTGCATCATTCTGGGAAATAACTATG
TACTTACCTTTCTTGAAAAAGAAACAGATTTCTTTGATGAAATCAACGCCGCATTGAGAAACGATATACTGAAAATCCGT
AGCCGTCTGACGGATTATCTGCTCAGTGTATTGCTGAACAGCATCATGGCGAACTACATTTCAACGATATCTTCCATCGA
CGATGCACTCGAAGACCTGGAAGAAGAACTGCTGATGATTACCAATGAGAATGACATCGGCATTCAGATTCAGGGGCTGC
GCCGCCAATATATGCTGATGAAAAAGGCCATCCTCCCGCTTAAAGAGCAATATGTAAAATTGTTGCGGGCAGAAAATCTC
CTTATACATAAAGTAAACCGTGCCTTCTACAATGATGTGAACGACCATTTACAATTTGTATTACAAACGATTGAAATCTG
CCGTGAAACACTGTCTTCATTAGTCGACCTGTATATCTCGAACAATGATTTACGAATGAACGATATCATGAAGCGGCTGA
CCATCGTATCCACCATTTTCATCCCGCTAACGTTTCTTGTCGGTGTGTGGGGAATGAATTACAAATGGATGCCCGAACTG
GACTGGCGGTACGGATATTTATTTGCCTGGATTATAATGGCGGTTATCGGTATTATTGTATATTTGTACTTCAGAAAAAA
GAAATGGTATTAA

Upstream 100 bases:

>100_bases
GATTTTGACTAATCTGAAAACAAAACGATCGAAGAACTTGTTCTCATTTAGAAAACCACTACCTTTGTGTTACAGTGGTT
TTCTAAAACGAGAATAAAGC

Downstream 100 bases:

>100_bases
CTAAAGCGCACCCATCCATGAAATCAATAAAAGAATTATACAGAATCGGCACAGGTCCTTCCAGCAGTCATACAATGGGC
CCTCGTAAAGCTGCAGAAAT

Product: Mg2+/Co2+ transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKNNLLSEKLIYTGDSLTPTHLHLCTYNATEMQESSGDTFQSVKETLDNERINWLQVHGLKDTETIREICSHFEIDFLVL
QDILNADHPTKIEEHDKYIVLILKIFYPNEHKEDDDLDGLLQQQVCIILGNNYVLTFLEKETDFFDEINAALRNDILKIR
SRLTDYLLSVLLNSIMANYISTISSIDDALEDLEEELLMITNENDIGIQIQGLRRQYMLMKKAILPLKEQYVKLLRAENL
LIHKVNRAFYNDVNDHLQFVLQTIEICRETLSSLVDLYISNNDLRMNDIMKRLTIVSTIFIPLTFLVGVWGMNYKWMPEL
DWRYGYLFAWIIMAVIGIIVYLYFRKKKWY

Sequences:

>Translated_350_residues
MKNNLLSEKLIYTGDSLTPTHLHLCTYNATEMQESSGDTFQSVKETLDNERINWLQVHGLKDTETIREICSHFEIDFLVL
QDILNADHPTKIEEHDKYIVLILKIFYPNEHKEDDDLDGLLQQQVCIILGNNYVLTFLEKETDFFDEINAALRNDILKIR
SRLTDYLLSVLLNSIMANYISTISSIDDALEDLEEELLMITNENDIGIQIQGLRRQYMLMKKAILPLKEQYVKLLRAENL
LIHKVNRAFYNDVNDHLQFVLQTIEICRETLSSLVDLYISNNDLRMNDIMKRLTIVSTIFIPLTFLVGVWGMNYKWMPEL
DWRYGYLFAWIIMAVIGIIVYLYFRKKKWY
>Mature_350_residues
MKNNLLSEKLIYTGDSLTPTHLHLCTYNATEMQESSGDTFQSVKETLDNERINWLQVHGLKDTETIREICSHFEIDFLVL
QDILNADHPTKIEEHDKYIVLILKIFYPNEHKEDDDLDGLLQQQVCIILGNNYVLTFLEKETDFFDEINAALRNDILKIR
SRLTDYLLSVLLNSIMANYISTISSIDDALEDLEEELLMITNENDIGIQIQGLRRQYMLMKKAILPLKEQYVKLLRAENL
LIHKVNRAFYNDVNDHLQFVLQTIEICRETLSSLVDLYISNNDLRMNDIMKRLTIVSTIFIPLTFLVGVWGMNYKWMPEL
DWRYGYLFAWIIMAVIGIIVYLYFRKKKWY

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=167, Percent_Identity=31.7365269461078, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41224; Mature: 41224

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNLLSEKLIYTGDSLTPTHLHLCTYNATEMQESSGDTFQSVKETLDNERINWLQVHGL
CCCCHHHHHHEECCCCCCCCEEEEEECCHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECC
KDTETIREICSHFEIDFLVLQDILNADHPTKIEEHDKYIVLILKIFYPNEHKEDDDLDGL
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHH
LQQQVCIILGNNYVLTFLEKETDFFDEINAALRNDILKIRSRLTDYLLSVLLNSIMANYI
HHHCEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STISSIDDALEDLEEELLMITNENDIGIQIQGLRRQYMLMKKAILPLKEQYVKLLRAENL
HHHHHHHHHHHHHHHHHEEEECCCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LIHKVNRAFYNDVNDHLQFVLQTIEICRETLSSLVDLYISNNDLRMNDIMKRLTIVSTIF
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IPLTFLVGVWGMNYKWMPELDWRYGYLFAWIIMAVIGIIVYLYFRKKKWY
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNNLLSEKLIYTGDSLTPTHLHLCTYNATEMQESSGDTFQSVKETLDNERINWLQVHGL
CCCCHHHHHHEECCCCCCCCEEEEEECCHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECC
KDTETIREICSHFEIDFLVLQDILNADHPTKIEEHDKYIVLILKIFYPNEHKEDDDLDGL
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHH
LQQQVCIILGNNYVLTFLEKETDFFDEINAALRNDILKIRSRLTDYLLSVLLNSIMANYI
HHHCEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STISSIDDALEDLEEELLMITNENDIGIQIQGLRRQYMLMKKAILPLKEQYVKLLRAENL
HHHHHHHHHHHHHHHHHEEEECCCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LIHKVNRAFYNDVNDHLQFVLQTIEICRETLSSLVDLYISNNDLRMNDIMKRLTIVSTIF
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IPLTFLVGVWGMNYKWMPELDWRYGYLFAWIIMAVIGIIVYLYFRKKKWY
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]