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The map label for this gene is sdaA [H]

Identifier: 29350086

GI number: 29350086

Start: 6133246

End: 6134481

Strand: Reverse

Name: sdaA [H]

Synonym: BT_4678

Alternate gene names: 29350086

Gene position: 6134481-6133246 (Counterclockwise)

Preceding gene: 29350087

Following gene: 29350081

Centisome position: 97.99

GC content: 48.46

Gene sequence:

>1236_bases
ATGGTATTAACTAAAGCGCACCCATCCATGAAATCAATAAAAGAATTATACAGAATCGGCACAGGTCCTTCCAGCAGTCA
TACAATGGGCCCTCGTAAAGCTGCAGAAATGTTTGTTGAACGTCACCCGGATGCCGCATCTTTCAAAGTAACCCTTTATG
GAAGTTTGGCAGCTACAGGCAAAGGGCACATGACGGATGTGGCTATCATAGATACTTTACAACCTGCCGCTCCGGTAGAA
ATCGTATGGCAACCCAAAGTTTTCCTCCCCTTCCATCCGAACGGAATGACGTTTGCTGCTCTGGATGCAGACAACAAGAT
ATTGGAAAACTGGACGGTTTACAGTATCGGTGGCGGAGCTTTGGCAGAGAATAATGACAACCCGACAATCGAAAGCCCGG
AAGTATACGGCATGAACAACATGACCGAAATCCTGCAATGGTGTGAACGTACCGGAAAAAGTTATTGGGAGTATGTCAAG
GAATGTGAGAACGAGGATATATGGGACTATCTGGCAGAAGTATGGGACACAATGAAAGACGCTATCCACCGAGGTCTGGA
AGCGGAAGGTGTATTGCCCGGACCGCTGAACTTACGTAGAAAAGCTTCCACCTATTATATACGTGCTACCGGATACAAAC
AATCTCTGCAATCCAGAGGACTCGTTTTCTCTTACGCACTGGCAGTCAGCGAAGAAAACGCTTCCGGTGGAAAGATCGTG
ACTGCCCCTACCTGTGGTTCCTGCGGAGTGATGCCGGCAGTACTTTATCATTTACAAAAAAGCCGTGACTTCAGTGACAT
GCGGATTCTTCGCGCCTTGGCTACAGCTGGGCTAATTGGAAACATTGTCAAGTTCAATGCGTCCATCTCCGGTGCGGAAG
TAGGATGTCAGGGAGAAGTCGGCGTTGCCTGCGCGATGGCATCAGCAGCAGCCAATCAATTATTCGGAGGAAGTCCGGCA
CAGATTGAATATGCTGCGGAAATGGGGCTGGAACACCACCTGGGGATGACTTGCGACCCCGTATGCGGTCTCGTTCAAAT
CCCTTGTATCGAGCGGAATGCTTATGCTGCTGCCCGTGCACTGGATGCCAATCTTTATTCAGCTTTTACAGACGGTATGC
ACCGTGTTTCTTTCGACAAAGTGGTACAGGTAATGAAACAAACCGGACATGACCTGCCCTCACTGTATAAGGAAACCAGC
GAAGGAGGACTGGCCAAAGATTATCAACAAATGTAA

Upstream 100 bases:

>100_bases
AATGGATGCCCGAACTGGACTGGCGGTACGGATATTTATTTGCCTGGATTATAATGGCGGTTATCGGTATTATTGTATAT
TTGTACTTCAGAAAAAAGAA

Downstream 100 bases:

>100_bases
TATAATGACTACAGAGGAGTGTCTGTCCACATTCCTCTGTACATAACTAATTCTACTCCATAACCGGCCAATTCGTATCA
TCGCCATTGGTGATATCCCT

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MVLTKAHPSMKSIKELYRIGTGPSSSHTMGPRKAAEMFVERHPDAASFKVTLYGSLAATGKGHMTDVAIIDTLQPAAPVE
IVWQPKVFLPFHPNGMTFAALDADNKILENWTVYSIGGGALAENNDNPTIESPEVYGMNNMTEILQWCERTGKSYWEYVK
ECENEDIWDYLAEVWDTMKDAIHRGLEAEGVLPGPLNLRRKASTYYIRATGYKQSLQSRGLVFSYALAVSEENASGGKIV
TAPTCGSCGVMPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKFNASISGAEVGCQGEVGVACAMASAAANQLFGGSPA
QIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARALDANLYSAFTDGMHRVSFDKVVQVMKQTGHDLPSLYKETS
EGGLAKDYQQM

Sequences:

>Translated_411_residues
MVLTKAHPSMKSIKELYRIGTGPSSSHTMGPRKAAEMFVERHPDAASFKVTLYGSLAATGKGHMTDVAIIDTLQPAAPVE
IVWQPKVFLPFHPNGMTFAALDADNKILENWTVYSIGGGALAENNDNPTIESPEVYGMNNMTEILQWCERTGKSYWEYVK
ECENEDIWDYLAEVWDTMKDAIHRGLEAEGVLPGPLNLRRKASTYYIRATGYKQSLQSRGLVFSYALAVSEENASGGKIV
TAPTCGSCGVMPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKFNASISGAEVGCQGEVGVACAMASAAANQLFGGSPA
QIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARALDANLYSAFTDGMHRVSFDKVVQVMKQTGHDLPSLYKETS
EGGLAKDYQQM
>Mature_411_residues
MVLTKAHPSMKSIKELYRIGTGPSSSHTMGPRKAAEMFVERHPDAASFKVTLYGSLAATGKGHMTDVAIIDTLQPAAPVE
IVWQPKVFLPFHPNGMTFAALDADNKILENWTVYSIGGGALAENNDNPTIESPEVYGMNNMTEILQWCERTGKSYWEYVK
ECENEDIWDYLAEVWDTMKDAIHRGLEAEGVLPGPLNLRRKASTYYIRATGYKQSLQSRGLVFSYALAVSEENASGGKIV
TAPTCGSCGVMPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKFNASISGAEVGCQGEVGVACAMASAAANQLFGGSPA
QIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARALDANLYSAFTDGMHRVSFDKVVQVMKQTGHDLPSLYKETS
EGGLAKDYQQM

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=40.9190371991247, Blast_Score=308, Evalue=5e-85,
Organism=Escherichia coli, GI1788116, Length=454, Percent_Identity=41.6299559471366, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1789161, Length=451, Percent_Identity=41.019955654102, Blast_Score=302, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 44655; Mature: 44655

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLTKAHPSMKSIKELYRIGTGPSSSHTMGPRKAAEMFVERHPDAASFKVTLYGSLAATG
CEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECC
KGHMTDVAIIDTLQPAAPVEIVWQPKVFLPFHPNGMTFAALDADNKILENWTVYSIGGGA
CCCCEEEEEEECCCCCCCEEEEECCEEEEEECCCCCEEEEECCCCHHHHCEEEEEECCCE
LAENNDNPTIESPEVYGMNNMTEILQWCERTGKSYWEYVKECENEDIWDYLAEVWDTMKD
ECCCCCCCCCCCCCEECCCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AIHRGLEAEGVLPGPLNLRRKASTYYIRATGYKQSLQSRGLVFSYALAVSEENASGGKIV
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCEEEEEEEEECCCCCCCEEE
TAPTCGSCGVMPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKFNASISGAEVGCQGEV
ECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCC
GVACAMASAAANQLFGGSPAQIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARA
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHCCCCCCCCCCCEECCCCCCCHHHHHHH
LDANLYSAFTDGMHRVSFDKVVQVMKQTGHDLPSLYKETSEGGLAKDYQQM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCC
>Mature Secondary Structure
MVLTKAHPSMKSIKELYRIGTGPSSSHTMGPRKAAEMFVERHPDAASFKVTLYGSLAATG
CEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECC
KGHMTDVAIIDTLQPAAPVEIVWQPKVFLPFHPNGMTFAALDADNKILENWTVYSIGGGA
CCCCEEEEEEECCCCCCCEEEEECCEEEEEECCCCCEEEEECCCCHHHHCEEEEEECCCE
LAENNDNPTIESPEVYGMNNMTEILQWCERTGKSYWEYVKECENEDIWDYLAEVWDTMKD
ECCCCCCCCCCCCCEECCCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AIHRGLEAEGVLPGPLNLRRKASTYYIRATGYKQSLQSRGLVFSYALAVSEENASGGKIV
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCEEEEEEEEECCCCCCCEEE
TAPTCGSCGVMPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKFNASISGAEVGCQGEV
ECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCC
GVACAMASAAANQLFGGSPAQIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARA
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHCCCCCCCCCCCEECCCCCCCHHHHHHH
LDANLYSAFTDGMHRVSFDKVVQVMKQTGHDLPSLYKETSEGGLAKDYQQM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]