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The map label for this gene is phoR [H]

Identifier: 29348743

GI number: 29348743

Start: 4289657

End: 4293721

Strand: Reverse

Name: phoR [H]

Synonym: BT_3334

Alternate gene names: 29348743

Gene position: 4293721-4289657 (Counterclockwise)

Preceding gene: 29348745

Following gene: 29348742

Centisome position: 68.59

GC content: 47.9

Gene sequence:

>4065_bases
GTGAGAAAAACAATCCTTTTATTTCTGCTATTTTTAAGCGTAACTGCTGTCCGTACGTTAGGACAAAATATTACTTTCAG
CCATTTGACCACAGATGACGGACTTTCCCAGTTTTCCGTCAACAGCCTGTACATTGACGAACGGGGCATTATATGGATAG
GTACGCGCGAAGGGCTGAACCGTTATAACGGTAACGATATCAAAAGTTTCAAGCTCAAGAAGAATGATCCGAACAGTCTG
TTCAGCAATACCGTACTCCGTATCACAGGTAATAAGAACGGGAAGGTTTACCTGCTTTGCACCGACGGTGTAGCCGAATT
TGACATGACCACTCAACGATTCAAAACCCTACTGCAAGGCAATGTGGACGCTATCTACTACAACGAAAAACTATATATCG
GAAAAAGAGAAGAAGTATTCGTTTTCAACGAGAACACGAACAACTTCGACCTTTACTACCACCTTGCCGGGAAAGACATT
AACCTATCCTGCCTCCATCTGGACGAGAAGAAAAACCTGTGGATGGGAACCACCAGCAATGGTGTTTACTGCCTGTCGGA
CGACAAGCAACTCTCTCAGCCCATCACGAAAGGAAACATAGCCAGCATCTACGAAGACTCATCCAAAGAACTGTGGATTG
GCAGCTGGGAGGAAGGGCTCTACCGTATCCGCACAAACGGCACTATCGACAACTTCCGCCACGACCCGAAGAATCCGAAC
AGTATATGTTCCGATTTTGTCAGAAGCTGCTGTGAAGATAATCTGGGAAATCTATGGATCGGAACTTTCCACGGCTTGAA
CCGCTACGACAAAAGCACAGGACAGTTCCAACTTTATACCGCCAATGACAACAAACCCGACGGACTCACCCACTCTTCCA
TCTGGTGTATCGTGAAAGACGAACAGGGAACCCTATGGCTGGGAACTTACTTTGGCGGCGTCAACTACTTCAATCCGGAA
TATGAAATCTATACCCGCTATAAAGTGGGAGACACGGAGAAAGAAGGATTAAGCAGTCCCATCGTCGGCAGAATGACGGA
AGACAAAGACGGTAACTTATGGATCTGCACCGAAGGCGGTGGCGTGAACGTCTACAACCGGAAAAACAATACTTATCGCT
GGTACCGCCACGAAGAAGGCAAGAACAGTATCTCGCACAACAACGTCAAGGCAATCTATTACGACCGGACAGAGGAGATT
ATGTGGATCGGCACACACTTGGGAGGACTGAACAAACTCGACCTGCGCACCAACCGCTTTACCGTTTACCGGATGAAAGC
GGGCGACCCGACCACACTGCCCTCGGACATTGTACGCGACATCGTGCCCTACGAAGACAAACTGATCATCGCCACACAAA
ATGGAGTCTGCCTTTTCAATCCGGCAACGGGCACCTGTGAACATCTTTTCAAGGATACCAAAGAAGGCAGAAATATCGGT
ATGGTGGCCAGCCTCTACATCGACAAGGATGAAACGCTATGGGTTTCCGCTACCGGAGAGGGCGTATATTCTTACCGCTT
CGACACCGGCAAGCTCACCCACTATGCACACAATCCCTCCATTCCGAACACTCTCAGCAACAACAATGTCAACAACATCA
TGCAAGACAGCAACGGCAACCTGTGGTTCTCCACTTCCGGAAGCGGGCTCGACCGTTACCGCAAGGAGAGCAACGACTTC
GAAAACTTCGACATGCAGAAAGACGGACTATCCAGCGACTGTATCTACGAAGTATTCGAATCGTCCATACAAAAGGGAGA
CTTGCTGCTGATTACCAATCAGGGATTCTCCCAGTTTGACTATCCGCAAAAGAAGTTTTACAACTACGGTACAGAGAACG
GATTCCCGCTGACTGCCGTCAACGAAAACGCATTGTTCGTAACGCATGACGGAGAAGTATTTCTAGGCGGCATCCAAGGC
ATGATTTCTTTCTGGGAAAAGAAACTGCACTTTACGCCCAAGTCCTACAGCATCATCCTTTCCCGCCTGCTGGTCAACGG
AAAGGAGATCACTGCCGGAGACGACACCGGCATCTTGGAACAGTCCATCGCCTATACACCGGAAATCAGCCTGAAAGCCG
ACCAATCCATGTTCAGCATAGAATACGCCACTTCCAACTTCATCCCTGCCAACAGGAATGAAATCGTCTACCGCCTCGAA
GGTTTCTCCGACGAATGGAATCACACCGACCGCAAACAGACGCTTATCACTTATACCAACCTGAATCCGGGCAAATATAC
GCTCGTCATCAAGTCGGACGGAGACGGTATCGAAGAAGCCCGACTACTGATCCGTGTATTACCGCCTTGGTATGAGACAT
GGTGGGCTTATCTGATTTACACCATTTGTACCGTCAGTCTGTTATGGTATCTCATTCAGAACTACAATTCCCGCATCAAA
CTGCGTGAGTCACTGAAATATGAAAAGAAGCACATCGAAGACCTCGAAGCATTAAACCAATCCAAGCTGCGCTTCTTTAC
CAACATCTCCCACGAATTCCGCACTCCGCTGACGTTGATCGTAGGACAGGTAGAAACGCTGTTGCAAGTACAGACATTCA
CACCTAATATTTATCACAAGATATTGGGAATTTACAAAAACAGCCTCCAACTGCGTGAACTAATTACGGAACTGCTCGAC
TTCCGCAAGCAGGAACAAGGGCACATGAAAATCAAAGTCAGCCGACATAATCTGGTGAACTTCCTGTACGAGAATTATCT
GTTATTCCTTGAATACGCCAGCAGCAAGCAAATCAATTTCAAGTTCAACAAGCAGTCGGATGATATTGAAGTATGGTACG
ACCAGAAGCAGATGCAGAAGGTAGTGAACAATCTGCTGTCCAACGCATTGAAGCATACGAAAGCGGAAGATACCATCTCC
ATCAACGTATCGCAGGAGGATAAATACGTCATTATCGAGATCAAAGACACGGGAACAGGCATTGCCGCCGCCGAGATCGA
CAAGATATTCGACCGTTTCTACCAGACCGAACGCCTCGACTCGCTGAATACCGGAGCCGGCACAGGCATCGGACTGGCGT
TGACAAAAGGTATCATCGAACTTCATCACGGAACCATCCGTGTAGAGAGCGAACCGGGCAAGGGAAGCCGTTTTATCATT
ACGTTGAAATCGGGCAACCAGCACTTTACTGAGGAACAAATCATACGGGACAATGCCGACGCCAACATTCAGCAACCACC
GGAAACAATCGTTCCAACCGTAGAAATACTGCCCGACTCCGAATGGAAGGAGGAAGATAATAAACGCATCGAAGATGCGA
AAATGCTGATAGTGGAAGACAACGAATCCATCAAACAAATGCTGGTAGGTATCTTCGAAACATTCTATCAGGTCACCACC
GCTTCCGATGGTGTAGAGGCATTGGATATCATACAGAAAGATATGCCAAGCATCATACTGAGTGACGTTGTCATGCCACG
TATGTCGGGTACGGAACTCTGTAAACAGGTCAAGACGGACTTCAACACCTGTCACATTCCGGTAGTACTACTGACGGCAC
GCACAGCCGTGGAACACAACATTGAAGGATTAAAAATCGGTGCGGACGATTATATCACCAAGCCGTTCAACACCAATCTC
CTGATCTCCCGTTGCAACAATCTGGTGAACTCACGGCGGTTGCTACAGGAGAAATTCAGCAAACAGCCACAGGCTTTTGC
CCAGATGCTTGCCACCAACCCGATGGATAAAGAAATGCTGGATCGTGCCATGGCCATCATCGAACAGCACTTGGATAATA
CGGACTTTAACGTCAACATCTTCGCCCGTGAAATGGGGATGGCACGTACCAATCTGTTCACGAAGCTGAAAGCCGTCACC
GGTCAGACACCGAACGACTTTATATTAAGTATCCGTCTCAAGAAAGGAGCCGTCATGCTGCGGAACAATCCGGAGCTGAA
CATTACGGAGATTTCCGACCGCATCGGTTTCTCTTCTTCCCGCTATTTCAGTAAATGCTTTAAGGAGATTTATCACGTCA
GTCCGCTTGCCTACCGCAAGGGTGAAGAAAAAGAGGAAGAAGGGAACGAAGAAACGGATCAATAA

Upstream 100 bases:

>100_bases
TTGGAGGATACAAATATAGTTACTTTCTCCTAATAAGGTTCCCGAAAATCAAATAAAAACAATATATTTGCCATTAGTAA
TACCCTAAACAACCGAATTA

Downstream 100 bases:

>100_bases
CCCACAAACAGGTAAGCAAGTAGCATTTGTAACAGGAGAACCTATGCCAAAGTAGTTCCCTCCTGTTGGCACACTTGTGC
CACGCTGCTGGCACGACCGT

Product: two-component system sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1354; Mature: 1354

Protein sequence:

>1354_residues
MRKTILLFLLFLSVTAVRTLGQNITFSHLTTDDGLSQFSVNSLYIDERGIIWIGTREGLNRYNGNDIKSFKLKKNDPNSL
FSNTVLRITGNKNGKVYLLCTDGVAEFDMTTQRFKTLLQGNVDAIYYNEKLYIGKREEVFVFNENTNNFDLYYHLAGKDI
NLSCLHLDEKKNLWMGTTSNGVYCLSDDKQLSQPITKGNIASIYEDSSKELWIGSWEEGLYRIRTNGTIDNFRHDPKNPN
SICSDFVRSCCEDNLGNLWIGTFHGLNRYDKSTGQFQLYTANDNKPDGLTHSSIWCIVKDEQGTLWLGTYFGGVNYFNPE
YEIYTRYKVGDTEKEGLSSPIVGRMTEDKDGNLWICTEGGGVNVYNRKNNTYRWYRHEEGKNSISHNNVKAIYYDRTEEI
MWIGTHLGGLNKLDLRTNRFTVYRMKAGDPTTLPSDIVRDIVPYEDKLIIATQNGVCLFNPATGTCEHLFKDTKEGRNIG
MVASLYIDKDETLWVSATGEGVYSYRFDTGKLTHYAHNPSIPNTLSNNNVNNIMQDSNGNLWFSTSGSGLDRYRKESNDF
ENFDMQKDGLSSDCIYEVFESSIQKGDLLLITNQGFSQFDYPQKKFYNYGTENGFPLTAVNENALFVTHDGEVFLGGIQG
MISFWEKKLHFTPKSYSIILSRLLVNGKEITAGDDTGILEQSIAYTPEISLKADQSMFSIEYATSNFIPANRNEIVYRLE
GFSDEWNHTDRKQTLITYTNLNPGKYTLVIKSDGDGIEEARLLIRVLPPWYETWWAYLIYTICTVSLLWYLIQNYNSRIK
LRESLKYEKKHIEDLEALNQSKLRFFTNISHEFRTPLTLIVGQVETLLQVQTFTPNIYHKILGIYKNSLQLRELITELLD
FRKQEQGHMKIKVSRHNLVNFLYENYLLFLEYASSKQINFKFNKQSDDIEVWYDQKQMQKVVNNLLSNALKHTKAEDTIS
INVSQEDKYVIIEIKDTGTGIAAAEIDKIFDRFYQTERLDSLNTGAGTGIGLALTKGIIELHHGTIRVESEPGKGSRFII
TLKSGNQHFTEEQIIRDNADANIQQPPETIVPTVEILPDSEWKEEDNKRIEDAKMLIVEDNESIKQMLVGIFETFYQVTT
ASDGVEALDIIQKDMPSIILSDVVMPRMSGTELCKQVKTDFNTCHIPVVLLTARTAVEHNIEGLKIGADDYITKPFNTNL
LISRCNNLVNSRRLLQEKFSKQPQAFAQMLATNPMDKEMLDRAMAIIEQHLDNTDFNVNIFAREMGMARTNLFTKLKAVT
GQTPNDFILSIRLKKGAVMLRNNPELNITEISDRIGFSSSRYFSKCFKEIYHVSPLAYRKGEEKEEEGNEETDQ

Sequences:

>Translated_1354_residues
MRKTILLFLLFLSVTAVRTLGQNITFSHLTTDDGLSQFSVNSLYIDERGIIWIGTREGLNRYNGNDIKSFKLKKNDPNSL
FSNTVLRITGNKNGKVYLLCTDGVAEFDMTTQRFKTLLQGNVDAIYYNEKLYIGKREEVFVFNENTNNFDLYYHLAGKDI
NLSCLHLDEKKNLWMGTTSNGVYCLSDDKQLSQPITKGNIASIYEDSSKELWIGSWEEGLYRIRTNGTIDNFRHDPKNPN
SICSDFVRSCCEDNLGNLWIGTFHGLNRYDKSTGQFQLYTANDNKPDGLTHSSIWCIVKDEQGTLWLGTYFGGVNYFNPE
YEIYTRYKVGDTEKEGLSSPIVGRMTEDKDGNLWICTEGGGVNVYNRKNNTYRWYRHEEGKNSISHNNVKAIYYDRTEEI
MWIGTHLGGLNKLDLRTNRFTVYRMKAGDPTTLPSDIVRDIVPYEDKLIIATQNGVCLFNPATGTCEHLFKDTKEGRNIG
MVASLYIDKDETLWVSATGEGVYSYRFDTGKLTHYAHNPSIPNTLSNNNVNNIMQDSNGNLWFSTSGSGLDRYRKESNDF
ENFDMQKDGLSSDCIYEVFESSIQKGDLLLITNQGFSQFDYPQKKFYNYGTENGFPLTAVNENALFVTHDGEVFLGGIQG
MISFWEKKLHFTPKSYSIILSRLLVNGKEITAGDDTGILEQSIAYTPEISLKADQSMFSIEYATSNFIPANRNEIVYRLE
GFSDEWNHTDRKQTLITYTNLNPGKYTLVIKSDGDGIEEARLLIRVLPPWYETWWAYLIYTICTVSLLWYLIQNYNSRIK
LRESLKYEKKHIEDLEALNQSKLRFFTNISHEFRTPLTLIVGQVETLLQVQTFTPNIYHKILGIYKNSLQLRELITELLD
FRKQEQGHMKIKVSRHNLVNFLYENYLLFLEYASSKQINFKFNKQSDDIEVWYDQKQMQKVVNNLLSNALKHTKAEDTIS
INVSQEDKYVIIEIKDTGTGIAAAEIDKIFDRFYQTERLDSLNTGAGTGIGLALTKGIIELHHGTIRVESEPGKGSRFII
TLKSGNQHFTEEQIIRDNADANIQQPPETIVPTVEILPDSEWKEEDNKRIEDAKMLIVEDNESIKQMLVGIFETFYQVTT
ASDGVEALDIIQKDMPSIILSDVVMPRMSGTELCKQVKTDFNTCHIPVVLLTARTAVEHNIEGLKIGADDYITKPFNTNL
LISRCNNLVNSRRLLQEKFSKQPQAFAQMLATNPMDKEMLDRAMAIIEQHLDNTDFNVNIFAREMGMARTNLFTKLKAVT
GQTPNDFILSIRLKKGAVMLRNNPELNITEISDRIGFSSSRYFSKCFKEIYHVSPLAYRKGEEKEEEGNEETDQ
>Mature_1354_residues
MRKTILLFLLFLSVTAVRTLGQNITFSHLTTDDGLSQFSVNSLYIDERGIIWIGTREGLNRYNGNDIKSFKLKKNDPNSL
FSNTVLRITGNKNGKVYLLCTDGVAEFDMTTQRFKTLLQGNVDAIYYNEKLYIGKREEVFVFNENTNNFDLYYHLAGKDI
NLSCLHLDEKKNLWMGTTSNGVYCLSDDKQLSQPITKGNIASIYEDSSKELWIGSWEEGLYRIRTNGTIDNFRHDPKNPN
SICSDFVRSCCEDNLGNLWIGTFHGLNRYDKSTGQFQLYTANDNKPDGLTHSSIWCIVKDEQGTLWLGTYFGGVNYFNPE
YEIYTRYKVGDTEKEGLSSPIVGRMTEDKDGNLWICTEGGGVNVYNRKNNTYRWYRHEEGKNSISHNNVKAIYYDRTEEI
MWIGTHLGGLNKLDLRTNRFTVYRMKAGDPTTLPSDIVRDIVPYEDKLIIATQNGVCLFNPATGTCEHLFKDTKEGRNIG
MVASLYIDKDETLWVSATGEGVYSYRFDTGKLTHYAHNPSIPNTLSNNNVNNIMQDSNGNLWFSTSGSGLDRYRKESNDF
ENFDMQKDGLSSDCIYEVFESSIQKGDLLLITNQGFSQFDYPQKKFYNYGTENGFPLTAVNENALFVTHDGEVFLGGIQG
MISFWEKKLHFTPKSYSIILSRLLVNGKEITAGDDTGILEQSIAYTPEISLKADQSMFSIEYATSNFIPANRNEIVYRLE
GFSDEWNHTDRKQTLITYTNLNPGKYTLVIKSDGDGIEEARLLIRVLPPWYETWWAYLIYTICTVSLLWYLIQNYNSRIK
LRESLKYEKKHIEDLEALNQSKLRFFTNISHEFRTPLTLIVGQVETLLQVQTFTPNIYHKILGIYKNSLQLRELITELLD
FRKQEQGHMKIKVSRHNLVNFLYENYLLFLEYASSKQINFKFNKQSDDIEVWYDQKQMQKVVNNLLSNALKHTKAEDTIS
INVSQEDKYVIIEIKDTGTGIAAAEIDKIFDRFYQTERLDSLNTGAGTGIGLALTKGIIELHHGTIRVESEPGKGSRFII
TLKSGNQHFTEEQIIRDNADANIQQPPETIVPTVEILPDSEWKEEDNKRIEDAKMLIVEDNESIKQMLVGIFETFYQVTT
ASDGVEALDIIQKDMPSIILSDVVMPRMSGTELCKQVKTDFNTCHIPVVLLTARTAVEHNIEGLKIGADDYITKPFNTNL
LISRCNNLVNSRRLLQEKFSKQPQAFAQMLATNPMDKEMLDRAMAIIEQHLDNTDFNVNIFAREMGMARTNLFTKLKAVT
GQTPNDFILSIRLKKGAVMLRNNPELNITEISDRIGFSSSRYFSKCFKEIYHVSPLAYRKGEEKEEEGNEETDQ

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=32.9501915708812, Blast_Score=131, Evalue=3e-31,
Organism=Escherichia coli, GI48994928, Length=440, Percent_Identity=24.5454545454545, Blast_Score=118, Evalue=3e-27,
Organism=Escherichia coli, GI1788713, Length=395, Percent_Identity=27.0886075949367, Blast_Score=113, Evalue=9e-26,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=29.2576419213974, Blast_Score=109, Evalue=1e-24,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=27.4678111587983, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1790436, Length=267, Percent_Identity=28.4644194756554, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=27.0588235294118, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=257, Percent_Identity=30.7392996108949, Blast_Score=94, Evalue=7e-20,
Organism=Escherichia coli, GI1789149, Length=254, Percent_Identity=30.3149606299213, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI1786912, Length=263, Percent_Identity=27.3764258555133, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=367, Percent_Identity=23.433242506812, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1786599, Length=112, Percent_Identity=39.2857142857143, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=30.4932735426009, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788394, Length=205, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1788550, Length=141, Percent_Identity=31.2056737588652, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87082012, Length=114, Percent_Identity=34.2105263157895, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=25.9414225941423, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=25.7028112449799, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1790860, Length=125, Percent_Identity=36, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1787375, Length=168, Percent_Identity=27.3809523809524, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=30.8333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790863, Length=122, Percent_Identity=35.2459016393443, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1789809, Length=139, Percent_Identity=27.3381294964029, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=262, Percent_Identity=22.9007633587786, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 155084; Mature: 155084

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTILLFLLFLSVTAVRTLGQNITFSHLTTDDGLSQFSVNSLYIDERGIIWIGTREGLN
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCCEEEEEEHHCCC
RYNGNDIKSFKLKKNDPNSLFSNTVLRITGNKNGKVYLLCTDGVAEFDMTTQRFKTLLQG
CCCCCCEEEEEECCCCCCHHHCCEEEEEEECCCCEEEEEECCCCCHHCHHHHHHHHHHHC
NVDAIYYNEKLYIGKREEVFVFNENTNNFDLYYHLAGKDINLSCLHLDEKKNLWMGTTSN
CCEEEEECCEEEECCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCCEEEEECCC
GVYCLSDDKQLSQPITKGNIASIYEDSSKELWIGSWEEGLYRIRTNGTIDNFRHDPKNPN
CEEEECCCHHHHCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCHHCCCCCCCCHH
SICSDFVRSCCEDNLGNLWIGTFHGLNRYDKSTGQFQLYTANDNKPDGLTHSSIWCIVKD
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEC
EQGTLWLGTYFGGVNYFNPEYEIYTRYKVGDTEKEGLSSPIVGRMTEDKDGNLWICTEGG
CCCCEEEEEEECCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEEEECCC
GVNVYNRKNNTYRWYRHEEGKNSISHNNVKAIYYDRTEEIMWIGTHLGGLNKLDLRTNRF
CEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCEE
TVYRMKAGDPTTLPSDIVRDIVPYEDKLIIATQNGVCLFNPATGTCEHLFKDTKEGRNIG
EEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHCCCCCC
MVASLYIDKDETLWVSATGEGVYSYRFDTGKLTHYAHNPSIPNTLSNNNVNNIMQDSNGN
EEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEECCCCC
LWFSTSGSGLDRYRKESNDFENFDMQKDGLSSDCIYEVFESSIQKGDLLLITNQGFSQFD
EEEEECCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCC
YPQKKFYNYGTENGFPLTAVNENALFVTHDGEVFLGGIQGMISFWEKKLHFTPKSYSIIL
CCHHHHHCCCCCCCCEEEEECCCEEEEEECCCEEECHHHHHHHHHHHHHCCCCCHHHHHH
SRLLVNGKEITAGDDTGILEQSIAYTPEISLKADQSMFSIEYATSNFIPANRNEIVYRLE
HHHHHCCCEEECCCCCCHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEEEE
GFSDEWNHTDRKQTLITYTNLNPGKYTLVIKSDGDGIEEARLLIRVLPPWYETWWAYLIY
CCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHEEECCCHHHHHHHHHHH
TICTVSLLWYLIQNYNSRIKLRESLKYEKKHIEDLEALNQSKLRFFTNISHEFRTPLTLI
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHCCCHHHH
VGQVETLLQVQTFTPNIYHKILGIYKNSLQLRELITELLDFRKQEQGHMKIKVSRHNLVN
HHHHHHHHEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
FLYENYLLFLEYASSKQINFKFNKQSDDIEVWYDQKQMQKVVNNLLSNALKHTKAEDTIS
HHHHCEEEEEEECCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEE
INVSQEDKYVIIEIKDTGTGIAAAEIDKIFDRFYQTERLDSLNTGAGTGIGLALTKGIIE
EEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHE
LHHGTIRVESEPGKGSRFIITLKSGNQHFTEEQIIRDNADANIQQPPETIVPTVEILPDS
EECCEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCHHHCCEEEECCCC
EWKEEDNKRIEDAKMLIVEDNESIKQMLVGIFETFYQVTTASDGVEALDIIQKDMPSIIL
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDVVMPRMSGTELCKQVKTDFNTCHIPVVLLTARTAVEHNIEGLKIGADDYITKPFNTNL
HHHHHCCCCHHHHHHHHHCCCCEEEEEEEEEEEHHHHHCCCCEEEECCCCCCCCCCCCCH
LISRCNNLVNSRRLLQEKFSKQPQAFAQMLATNPMDKEMLDRAMAIIEQHLDNTDFNVNI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
FAREMGMARTNLFTKLKAVTGQTPNDFILSIRLKKGAVMLRNNPELNITEISDRIGFSSS
EEEHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEECCCCEEEEEHHHHCCCCCH
RYFSKCFKEIYHVSPLAYRKGEEKEEEGNEETDQ
HHHHHHHHHHHHCCCHHHCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MRKTILLFLLFLSVTAVRTLGQNITFSHLTTDDGLSQFSVNSLYIDERGIIWIGTREGLN
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCCEEEEEEHHCCC
RYNGNDIKSFKLKKNDPNSLFSNTVLRITGNKNGKVYLLCTDGVAEFDMTTQRFKTLLQG
CCCCCCEEEEEECCCCCCHHHCCEEEEEEECCCCEEEEEECCCCCHHCHHHHHHHHHHHC
NVDAIYYNEKLYIGKREEVFVFNENTNNFDLYYHLAGKDINLSCLHLDEKKNLWMGTTSN
CCEEEEECCEEEECCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCCEEEEECCC
GVYCLSDDKQLSQPITKGNIASIYEDSSKELWIGSWEEGLYRIRTNGTIDNFRHDPKNPN
CEEEECCCHHHHCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCHHCCCCCCCCHH
SICSDFVRSCCEDNLGNLWIGTFHGLNRYDKSTGQFQLYTANDNKPDGLTHSSIWCIVKD
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEC
EQGTLWLGTYFGGVNYFNPEYEIYTRYKVGDTEKEGLSSPIVGRMTEDKDGNLWICTEGG
CCCCEEEEEEECCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEEEECCC
GVNVYNRKNNTYRWYRHEEGKNSISHNNVKAIYYDRTEEIMWIGTHLGGLNKLDLRTNRF
CEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCEE
TVYRMKAGDPTTLPSDIVRDIVPYEDKLIIATQNGVCLFNPATGTCEHLFKDTKEGRNIG
EEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHCCCCCC
MVASLYIDKDETLWVSATGEGVYSYRFDTGKLTHYAHNPSIPNTLSNNNVNNIMQDSNGN
EEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEECCCCC
LWFSTSGSGLDRYRKESNDFENFDMQKDGLSSDCIYEVFESSIQKGDLLLITNQGFSQFD
EEEEECCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCC
YPQKKFYNYGTENGFPLTAVNENALFVTHDGEVFLGGIQGMISFWEKKLHFTPKSYSIIL
CCHHHHHCCCCCCCCEEEEECCCEEEEEECCCEEECHHHHHHHHHHHHHCCCCCHHHHHH
SRLLVNGKEITAGDDTGILEQSIAYTPEISLKADQSMFSIEYATSNFIPANRNEIVYRLE
HHHHHCCCEEECCCCCCHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEEEE
GFSDEWNHTDRKQTLITYTNLNPGKYTLVIKSDGDGIEEARLLIRVLPPWYETWWAYLIY
CCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHEEECCCHHHHHHHHHHH
TICTVSLLWYLIQNYNSRIKLRESLKYEKKHIEDLEALNQSKLRFFTNISHEFRTPLTLI
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHCCCHHHH
VGQVETLLQVQTFTPNIYHKILGIYKNSLQLRELITELLDFRKQEQGHMKIKVSRHNLVN
HHHHHHHHEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
FLYENYLLFLEYASSKQINFKFNKQSDDIEVWYDQKQMQKVVNNLLSNALKHTKAEDTIS
HHHHCEEEEEEECCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEE
INVSQEDKYVIIEIKDTGTGIAAAEIDKIFDRFYQTERLDSLNTGAGTGIGLALTKGIIE
EEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHE
LHHGTIRVESEPGKGSRFIITLKSGNQHFTEEQIIRDNADANIQQPPETIVPTVEILPDS
EECCEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCHHHCCEEEECCCC
EWKEEDNKRIEDAKMLIVEDNESIKQMLVGIFETFYQVTTASDGVEALDIIQKDMPSIIL
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDVVMPRMSGTELCKQVKTDFNTCHIPVVLLTARTAVEHNIEGLKIGADDYITKPFNTNL
HHHHHCCCCHHHHHHHHHCCCCEEEEEEEEEEEHHHHHCCCCEEEECCCCCCCCCCCCCH
LISRCNNLVNSRRLLQEKFSKQPQAFAQMLATNPMDKEMLDRAMAIIEQHLDNTDFNVNI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
FAREMGMARTNLFTKLKAVTGQTPNDFILSIRLKKGAVMLRNNPELNITEISDRIGFSSS
EEEHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEECCCCEEEEEHHHHCCCCCH
RYFSKCFKEIYHVSPLAYRKGEEKEEEGNEETDQ
HHHHHHHHHHHHCCCHHHCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]