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The map label for this gene is lpxA [H]

Identifier: 29348745

GI number: 29348745

Start: 4294535

End: 4295305

Strand: Reverse

Name: lpxA [H]

Synonym: BT_3336

Alternate gene names: 29348745

Gene position: 4295305-4294535 (Counterclockwise)

Preceding gene: 29348746

Following gene: 29348743

Centisome position: 68.61

GC content: 43.97

Gene sequence:

>771_bases
ATGATTAGTCCGTTAGCTTACGTAGACCCCGAAGCGAAATTAGGCAAGAATGTAACTGTCTTGCCTTTCGCCTACATCGA
GAAAGATGTGGAAATCGGCGATGACTGTACCATCATGTCATACGCCAGTATCCTGAAAGGTACAAAAATGGGGAAAGGAA
ACAAAATACATCAGAATGCTGTCCTGGGAGCAGAACCGCAAGACTTTCACTATACAGGGGAAGAAAGCAGTCTGATCATC
GGAGACAATAACGATATCCGTGAGAATGTAGTAATCAGCCGTGCCACTTTTGCAGGAAATGCTACCAGAATTGGAAACGG
GAACTACCTGATGGATAAGGTACACCTTTGCCATGATGTGCAGATCAGCAATAATTGTGTGGTAGGAATAGGTACTACAA
TTGCAGGAGAATGCTCATTAGATGATTGTGTGATCCTAAGCGGCAACGTAACGTTGCACCAATATTGTCACATTGGTAGC
TGGACACTTGTACAAAGCGGATGCCGCATCTCCAAAGATGTTCCTCCCTACGTAATTATGTCCGGCAATCCTGTTGCCTA
TCATGGAGTGAATGCAGTCGTTCTGTCACAGCATCACAATACGTCGGAAAGAATCCTTCGTCATATTGCCAATGCTTACC
GGTTGATCTATCAAGGTAATTTCAGTGTTCAGGATGCTGTCCAGAAGATTATCGATCAGGTTCCGATGAGTGAAGAAATC
GAGAATATCGTGAATTTCGTAAAAGGTTCGGAACGTGGGATTGTGAAATAG

Upstream 100 bases:

>100_bases
TTCTCAGGTTTCCGACTGTTTCGACAAGATGCAGGCTGTGGTCAGCCTCTACCAGGCATTAGGCGGTGGAAGAGAAGATT
AACTTTAAACATATACTATT

Downstream 100 bases:

>100_bases
ACAAAATACACTTTTCATAGAGAAAGGGTGATGTCTTTTTACGGACATCACCCTTCTTATTTATTCAAACTCCAGCGTAC
CGAAGAAGTCGGGACGATGG

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MISPLAYVDPEAKLGKNVTVLPFAYIEKDVEIGDDCTIMSYASILKGTKMGKGNKIHQNAVLGAEPQDFHYTGEESSLII
GDNNDIRENVVISRATFAGNATRIGNGNYLMDKVHLCHDVQISNNCVVGIGTTIAGECSLDDCVILSGNVTLHQYCHIGS
WTLVQSGCRISKDVPPYVIMSGNPVAYHGVNAVVLSQHHNTSERILRHIANAYRLIYQGNFSVQDAVQKIIDQVPMSEEI
ENIVNFVKGSERGIVK

Sequences:

>Translated_256_residues
MISPLAYVDPEAKLGKNVTVLPFAYIEKDVEIGDDCTIMSYASILKGTKMGKGNKIHQNAVLGAEPQDFHYTGEESSLII
GDNNDIRENVVISRATFAGNATRIGNGNYLMDKVHLCHDVQISNNCVVGIGTTIAGECSLDDCVILSGNVTLHQYCHIGS
WTLVQSGCRISKDVPPYVIMSGNPVAYHGVNAVVLSQHHNTSERILRHIANAYRLIYQGNFSVQDAVQKIIDQVPMSEEI
ENIVNFVKGSERGIVK
>Mature_256_residues
MISPLAYVDPEAKLGKNVTVLPFAYIEKDVEIGDDCTIMSYASILKGTKMGKGNKIHQNAVLGAEPQDFHYTGEESSLII
GDNNDIRENVVISRATFAGNATRIGNGNYLMDKVHLCHDVQISNNCVVGIGTTIAGECSLDDCVILSGNVTLHQYCHIGS
WTLVQSGCRISKDVPPYVIMSGNPVAYHGVNAVVLSQHHNTSERILRHIANAYRLIYQGNFSVQDAVQKIIDQVPMSEEI
ENIVNFVKGSERGIVK

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=257, Percent_Identity=35.0194552529183, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1786376, Length=188, Percent_Identity=29.2553191489362, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27974; Mature: 27974

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPLAYVDPEAKLGKNVTVLPFAYIEKDVEIGDDCTIMSYASILKGTKMGKGNKIHQNA
CCCCCCCCCCHHHHCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCC
VLGAEPQDFHYTGEESSLIIGDNNDIRENVVISRATFAGNATRIGNGNYLMDKVHLCHDV
EECCCCCCCEECCCCCEEEEECCCCCCCCEEEEEEEECCCCEEECCCCEEEEEEEEEEEE
QISNNCVVGIGTTIAGECSLDDCVILSGNVTLHQYCHIGSWTLVQSGCRISKDVPPYVIM
EECCCEEEEECCEEECCCCCCCEEEEECCEEEEEEEECCCCHHHHCCCCCCCCCCCEEEE
SGNPVAYHGVNAVVLSQHHNTSERILRHIANAYRLIYQGNFSVQDAVQKIIDQVPMSEEI
CCCEEEECCCCEEEEECCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCHHHH
ENIVNFVKGSERGIVK
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISPLAYVDPEAKLGKNVTVLPFAYIEKDVEIGDDCTIMSYASILKGTKMGKGNKIHQNA
CCCCCCCCCCHHHHCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCC
VLGAEPQDFHYTGEESSLIIGDNNDIRENVVISRATFAGNATRIGNGNYLMDKVHLCHDV
EECCCCCCCEECCCCCEEEEECCCCCCCCEEEEEEEECCCCEEECCCCEEEEEEEEEEEE
QISNNCVVGIGTTIAGECSLDDCVILSGNVTLHQYCHIGSWTLVQSGCRISKDVPPYVIM
EECCCEEEEECCEEECCCCCCCEEEEECCEEEEEEEECCCCHHHHCCCCCCCCCCCEEEE
SGNPVAYHGVNAVVLSQHHNTSERILRHIANAYRLIYQGNFSVQDAVQKIIDQVPMSEEI
CCCEEEECCCCEEEEECCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCHHHH
ENIVNFVKGSERGIVK
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA