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The map label for this gene is dtd

Identifier: 29348674

GI number: 29348674

Start: 4168394

End: 4168846

Strand: Reverse

Name: dtd

Synonym: BT_3265

Alternate gene names: 29348674

Gene position: 4168846-4168394 (Counterclockwise)

Preceding gene: 29348675

Following gene: 29348673

Centisome position: 66.59

GC content: 45.25

Gene sequence:

>453_bases
ATGAGAATAGTTGTACAACGAGTAAGCCACGCATCAGTAACCATCGAAGGACAGTGCAAGTCTTCCATTGGAAAAGGGAT
GCTGATATTAGTCGGCATTGAAGAATCCGACGGACAGGAAGATATAGACTGGCTCTGCAAAAAGATAGTAAATCTGCGTA
TTTTTGACGATGAAAGCGGAGTAATGAACAAGTCGATCCTGGAAGATGGAGGTGAAATTCTGGTCATCAGTCAGTTCACG
TTGCACGCTTCTACCAAGAAGGGCAACCGTCCGTCATACATCAAAGCCGCCAAGCCGGAGATATCTGTCCCACTCTACGA
ACGGTTCTGCAAAGACCTGAGCAGGGCGCTGGGAAAAGAAATCGGCACAGGAACTTTCGGAGCGGACATGAAAGTTGAAC
TTTTAAATGACGGTCCTGTTACTATATGTATGGACACCAAAAATAAAGAGTAA

Upstream 100 bases:

>100_bases
ATACTTATCTCCTATAATATTTCCTTCCAATCCATCGTTTTTTCTTCTTAATTTCGTAAATTTGCCTTTCGTAACATTCA
ATAGAATAGAGAAAATATCA

Downstream 100 bases:

>100_bases
AACCTTGATGAAAAAGCCGGTAAAGCTCTTCGAAGAGTGATAAACAGGCTCTAAACATCAAACTAATCATCATAAACCAA
CAGCAATTATGACCCTGGAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRIVVQRVSHASVTIEGQCKSSIGKGMLILVGIEESDGQEDIDWLCKKIVNLRIFDDESGVMNKSILEDGGEILVISQFT
LHASTKKGNRPSYIKAAKPEISVPLYERFCKDLSRALGKEIGTGTFGADMKVELLNDGPVTICMDTKNKE

Sequences:

>Translated_150_residues
MRIVVQRVSHASVTIEGQCKSSIGKGMLILVGIEESDGQEDIDWLCKKIVNLRIFDDESGVMNKSILEDGGEILVISQFT
LHASTKKGNRPSYIKAAKPEISVPLYERFCKDLSRALGKEIGTGTFGADMKVELLNDGPVTICMDTKNKE
>Mature_150_residues
MRIVVQRVSHASVTIEGQCKSSIGKGMLILVGIEESDGQEDIDWLCKKIVNLRIFDDESGVMNKSILEDGGEILVISQFT
LHASTKKGNRPSYIKAAKPEISVPLYERFCKDLSRALGKEIGTGTFGADMKVELLNDGPVTICMDTKNKE

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=43.2432432432432, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790320, Length=146, Percent_Identity=43.8356164383562, Blast_Score=133, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=37.7483443708609, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=49.3243243243243, Blast_Score=130, Evalue=8e-32,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=42.1768707482993, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_BACTN (Q8A2P0)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_812177.1
- ProteinModelPortal:   Q8A2P0
- SMR:   Q8A2P0
- GeneID:   1072846
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_3265
- NMPDR:   fig|226186.1.peg.3264
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q8A2P0
- ProtClustDB:   PRK05273
- BioCyc:   BTHE226186:BT_3265-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16489; Mature: 16489

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVVQRVSHASVTIEGQCKSSIGKGMLILVGIEESDGQEDIDWLCKKIVNLRIFDDESG
CEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHEEEEEECCCC
VMNKSILEDGGEILVISQFTLHASTKKGNRPSYIKAAKPEISVPLYERFCKDLSRALGKE
CCCHHHHHCCCCEEEEEEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
IGTGTFGADMKVELLNDGPVTICMDTKNKE
CCCCCCCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRIVVQRVSHASVTIEGQCKSSIGKGMLILVGIEESDGQEDIDWLCKKIVNLRIFDDESG
CEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHEEEEEECCCC
VMNKSILEDGGEILVISQFTLHASTKKGNRPSYIKAAKPEISVPLYERFCKDLSRALGKE
CCCHHHHHCCCCEEEEEEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
IGTGTFGADMKVELLNDGPVTICMDTKNKE
CCCCCCCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928