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The map label for this gene is atsA [H]

Identifier: 29348502

GI number: 29348502

Start: 3928001

End: 3929623

Strand: Reverse

Name: atsA [H]

Synonym: BT_3093

Alternate gene names: 29348502

Gene position: 3929623-3928001 (Counterclockwise)

Preceding gene: 29348503

Following gene: 29348501

Centisome position: 62.77

GC content: 43.25

Gene sequence:

>1623_bases
ATGACTTTTGCACAAGAAAAGCCTAATATCATTGTTATATTGGCGGACGATCTGGGTTTCTCCGATTTAGGTTGCTACGG
AGGAGAAGTACAGACACCGGTATTGGATAAGATGGCCAAACAGGGTGTCCGTATGACACAAATGTATAACAGTGCGCGGA
GTTGTCCGTCACGTGCCAATTTATTAACCGGACTTTATCCGCATCAGACAGGGTTAGGACACATGGATGCAACCCGTCCG
GCATGGCCGAAAGGATATGCCGGCTTTCGTTCCAATTCTGACAACGTTACCATTGCCGAAGTATTAAAAGATGCCGGATA
TTTCACAGCCATGTCCGGTAAATGGCATCTGGGCAAAACCGCCAATCCGATAAACCGAGGTTTCCTGGAATATTATGGTT
TGTTAGGTGGATTCAATTCTTTTTGGAATCCGGACGTATATACCCGATTGCCTAAGGATCGTAACCCACGTCAATATAAA
GAGGGAGAATTTTATGCTACTAACGTAATAACCGATTATGCCATAGACTTTATTAATCAGGCACATCAGGAAGAAAAACC
TTTGTTTCTGTATTTGGCATACAATGCTGCTCATTTTCCGTTGCACGCTCCGAAAGAAGTAACGGATAAATATATGAAGA
TTTACCTGCAGGGTTGGGATAAGATTCGAGATCAACGTTGGAAACGAATAGTAAAGATGGGGCTTTTGCAAGGAAAACCA
GCATTAAGCCCGCGTGGTGTTGTTCCCGAAAGTTTGTTTGAGGATGAGACACATCCGCTGCCTGCCTGGGATTCTTTAAC
AAAGGAACAGCAGACTGACCTGGCTCGCCGTATGGCTATTTATGCTGCCATGATAGATATTATGGATACCAATATTGGTC
GGGTATTGGATACTTTACAGAAGAACGGTGAACTGGATAATACATTTATCATGTTCATGTCGGACAACGGAGCTTGTGCC
GAATGGCATGAATTTGGTTTCGACAAGCAAACTGGAACAGAATATCATACTCATGTTGGTGCTGAATTAGACCAGATGGG
ACTACCGGGAACTTATCATCATTACGGAACCGGCTGGGCAAACGTTTGTTGTACCCCATTTACACTTTATAAACATTATG
CGCATGAAGGTGGAATATCCACTCCTTGCATTATCCAGTGGGGTAAACAGATTAAGCACAAAGGCAGTATTGACCATCAA
CCGGCACAATTCTCGGATATCATGGCAACTTGCATCGAACTGGCAGGGACTAAATATCCCGAAGAATACGAAGGAAGAAA
GATTGTACCTACACCGGGCAAGTCAATCCTTCCTATTGTACGCGGTGAAGAAATGCCGGACCGTTATATCTATGCGGAAC
ATGAAGGTAATCGTATGGTACGCAAAGGTGACTGGAAACTGGTCTCTGCGAATTTTAGAGGTGATGAATGGGAACTCTAT
AATATCAAAGAAGACCGCACAGAACAACATAATCTGATAAAGGAATACCCTGAAATGGCAAAGGAACTGGAAGACGCTTA
TTTTGAGTGGGCAGACCATAGTGATGTGCTTTATTTCCCGAAGGTTTGGAATACTTATAATAAAGGACGCCGGAAGGACT
TTAAAGAATATAGAGATAAGTAG

Upstream 100 bases:

>100_bases
TTCCGATGCTTTATGAAAACGGAAAATTTAAACCTAATCACAATTATCAGGCAAAATGAAAACATCACTATTGATAACCG
GGGGATTGGCTTTCGGAGCA

Downstream 100 bases:

>100_bases
GAAAACACAGTAGGAAAGAAAAGATAGGAACTTATGAACAAGAAACTACTAATTGCAGTATTTGTAAGTGCTATGGCACA
TACGTTCGCTTGCGCAGCAA

Product: arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MTFAQEKPNIIVILADDLGFSDLGCYGGEVQTPVLDKMAKQGVRMTQMYNSARSCPSRANLLTGLYPHQTGLGHMDATRP
AWPKGYAGFRSNSDNVTIAEVLKDAGYFTAMSGKWHLGKTANPINRGFLEYYGLLGGFNSFWNPDVYTRLPKDRNPRQYK
EGEFYATNVITDYAIDFINQAHQEEKPLFLYLAYNAAHFPLHAPKEVTDKYMKIYLQGWDKIRDQRWKRIVKMGLLQGKP
ALSPRGVVPESLFEDETHPLPAWDSLTKEQQTDLARRMAIYAAMIDIMDTNIGRVLDTLQKNGELDNTFIMFMSDNGACA
EWHEFGFDKQTGTEYHTHVGAELDQMGLPGTYHHYGTGWANVCCTPFTLYKHYAHEGGISTPCIIQWGKQIKHKGSIDHQ
PAQFSDIMATCIELAGTKYPEEYEGRKIVPTPGKSILPIVRGEEMPDRYIYAEHEGNRMVRKGDWKLVSANFRGDEWELY
NIKEDRTEQHNLIKEYPEMAKELEDAYFEWADHSDVLYFPKVWNTYNKGRRKDFKEYRDK

Sequences:

>Translated_540_residues
MTFAQEKPNIIVILADDLGFSDLGCYGGEVQTPVLDKMAKQGVRMTQMYNSARSCPSRANLLTGLYPHQTGLGHMDATRP
AWPKGYAGFRSNSDNVTIAEVLKDAGYFTAMSGKWHLGKTANPINRGFLEYYGLLGGFNSFWNPDVYTRLPKDRNPRQYK
EGEFYATNVITDYAIDFINQAHQEEKPLFLYLAYNAAHFPLHAPKEVTDKYMKIYLQGWDKIRDQRWKRIVKMGLLQGKP
ALSPRGVVPESLFEDETHPLPAWDSLTKEQQTDLARRMAIYAAMIDIMDTNIGRVLDTLQKNGELDNTFIMFMSDNGACA
EWHEFGFDKQTGTEYHTHVGAELDQMGLPGTYHHYGTGWANVCCTPFTLYKHYAHEGGISTPCIIQWGKQIKHKGSIDHQ
PAQFSDIMATCIELAGTKYPEEYEGRKIVPTPGKSILPIVRGEEMPDRYIYAEHEGNRMVRKGDWKLVSANFRGDEWELY
NIKEDRTEQHNLIKEYPEMAKELEDAYFEWADHSDVLYFPKVWNTYNKGRRKDFKEYRDK
>Mature_539_residues
TFAQEKPNIIVILADDLGFSDLGCYGGEVQTPVLDKMAKQGVRMTQMYNSARSCPSRANLLTGLYPHQTGLGHMDATRPA
WPKGYAGFRSNSDNVTIAEVLKDAGYFTAMSGKWHLGKTANPINRGFLEYYGLLGGFNSFWNPDVYTRLPKDRNPRQYKE
GEFYATNVITDYAIDFINQAHQEEKPLFLYLAYNAAHFPLHAPKEVTDKYMKIYLQGWDKIRDQRWKRIVKMGLLQGKPA
LSPRGVVPESLFEDETHPLPAWDSLTKEQQTDLARRMAIYAAMIDIMDTNIGRVLDTLQKNGELDNTFIMFMSDNGACAE
WHEFGFDKQTGTEYHTHVGAELDQMGLPGTYHHYGTGWANVCCTPFTLYKHYAHEGGISTPCIIQWGKQIKHKGSIDHQP
AQFSDIMATCIELAGTKYPEEYEGRKIVPTPGKSILPIVRGEEMPDRYIYAEHEGNRMVRKGDWKLVSANFRGDEWELYN
IKEDRTEQHNLIKEYPEMAKELEDAYFEWADHSDVLYFPKVWNTYNKGRRKDFKEYRDK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569405, Length=581, Percent_Identity=25.6454388984509, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI38569407, Length=329, Percent_Identity=30.6990881458967, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI109389362, Length=224, Percent_Identity=37.5, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI53831991, Length=484, Percent_Identity=25.8264462809917, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI59797060, Length=220, Percent_Identity=37.2727272727273, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI157266309, Length=513, Percent_Identity=25.7309941520468, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI31742482, Length=454, Percent_Identity=27.3127753303965, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI71852584, Length=483, Percent_Identity=25.0517598343685, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI58743319, Length=329, Percent_Identity=27.0516717325228, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4503899, Length=219, Percent_Identity=34.703196347032, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI71852586, Length=139, Percent_Identity=41.0071942446043, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI146229331, Length=225, Percent_Identity=32.8888888888889, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI146229329, Length=225, Percent_Identity=32.8888888888889, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI6005990, Length=225, Percent_Identity=32.8888888888889, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI146229324, Length=225, Percent_Identity=32.8888888888889, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI45430057, Length=333, Percent_Identity=28.5285285285285, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1790112, Length=533, Percent_Identity=23.0769230769231, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790233, Length=233, Percent_Identity=31.7596566523605, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081924, Length=266, Percent_Identity=27.0676691729323, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533416, Length=529, Percent_Identity=22.6843100189036, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17559078, Length=217, Percent_Identity=33.1797235023041, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533418, Length=519, Percent_Identity=22.7360308285164, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24666175, Length=459, Percent_Identity=26.5795206971678, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281366397, Length=234, Percent_Identity=32.9059829059829, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281366395, Length=234, Percent_Identity=32.9059829059829, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666163, Length=234, Percent_Identity=32.9059829059829, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666109, Length=230, Percent_Identity=34.7826086956522, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI281363223, Length=208, Percent_Identity=35.5769230769231, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24653364, Length=349, Percent_Identity=24.6418338108883, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21356831, Length=563, Percent_Identity=22.0248667850799, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 62070; Mature: 61939

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAQEKPNIIVILADDLGFSDLGCYGGEVQTPVLDKMAKQGVRMTQMYNSARSCPSRAN
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHH
LLTGLYPHQTGLGHMDATRPAWPKGYAGFRSNSDNVTIAEVLKDAGYFTAMSGKWHLGKT
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEEEECCCEECCCC
ANPINRGFLEYYGLLGGFNSFWNPDVYTRLPKDRNPRQYKEGEFYATNVITDYAIDFINQ
CCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
AHQEEKPLFLYLAYNAAHFPLHAPKEVTDKYMKIYLQGWDKIRDQRWKRIVKMGLLQGKP
HHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ALSPRGVVPESLFEDETHPLPAWDSLTKEQQTDLARRMAIYAAMIDIMDTNIGRVLDTLQ
CCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KNGELDNTFIMFMSDNGACAEWHEFGFDKQTGTEYHTHVGAELDQMGLPGTYHHYGTGWA
HCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCHHHHCCCCHHHCCCCCCCCCCCCCHH
NVCCTPFTLYKHYAHEGGISTPCIIQWGKQIKHKGSIDHQPAQFSDIMATCIELAGTKYP
HHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCC
EEYEGRKIVPTPGKSILPIVRGEEMPDRYIYAEHEGNRMVRKGDWKLVSANFRGDEWELY
HHHCCCEECCCCCCCCCCEECCCCCCCCEEEEECCCCCCEEECCEEEEEECCCCCCEEEE
NIKEDRTEQHNLIKEYPEMAKELEDAYFEWADHSDVLYFPKVWNTYNKGRRKDFKEYRDK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHCHHHHHHHHHHCCC
>Mature Secondary Structure 
TFAQEKPNIIVILADDLGFSDLGCYGGEVQTPVLDKMAKQGVRMTQMYNSARSCPSRAN
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHH
LLTGLYPHQTGLGHMDATRPAWPKGYAGFRSNSDNVTIAEVLKDAGYFTAMSGKWHLGKT
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEEEECCCEECCCC
ANPINRGFLEYYGLLGGFNSFWNPDVYTRLPKDRNPRQYKEGEFYATNVITDYAIDFINQ
CCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
AHQEEKPLFLYLAYNAAHFPLHAPKEVTDKYMKIYLQGWDKIRDQRWKRIVKMGLLQGKP
HHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ALSPRGVVPESLFEDETHPLPAWDSLTKEQQTDLARRMAIYAAMIDIMDTNIGRVLDTLQ
CCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KNGELDNTFIMFMSDNGACAEWHEFGFDKQTGTEYHTHVGAELDQMGLPGTYHHYGTGWA
HCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCHHHHCCCCHHHCCCCCCCCCCCCCHH
NVCCTPFTLYKHYAHEGGISTPCIIQWGKQIKHKGSIDHQPAQFSDIMATCIELAGTKYP
HHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCC
EEYEGRKIVPTPGKSILPIVRGEEMPDRYIYAEHEGNRMVRKGDWKLVSANFRGDEWELY
HHHCCCEECCCCCCCCCCEECCCCCCCCEEEEECCCCCCEEECCEEEEEECCCCCCEEEE
NIKEDRTEQHNLIKEYPEMAKELEDAYFEWADHSDVLYFPKVWNTYNKGRRKDFKEYRDK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]