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The map label for this gene is aatA [H]

Identifier: 29347825

GI number: 29347825

Start: 3015626

End: 3016819

Strand: Reverse

Name: aatA [H]

Synonym: BT_2415

Alternate gene names: 29347825

Gene position: 3016819-3015626 (Counterclockwise)

Preceding gene: 29347826

Following gene: 29347823

Centisome position: 48.19

GC content: 45.56

Gene sequence:

>1194_bases
ATGAATCAATTATCAGATCGTTTGAACAGCTTGTCGCCGTCGGCGACGCTTGCCATGTCGCAAAAGAGCAACGAACTCAA
AGCGCAGGGTATTGATGTTATTAACTTAAGTGTAGGAGAACCGGATTTCAATACTCCTGACCACATCAAAGAAGCTGCGA
AGAAAGCCATTGATGATAACTTTTCTCGCTACTCTCCGGTACCGGGTTATCCGGCTTTACGCAATGCGATTGTTGAGAAG
CTGAAAAAAGAGAACGGTCTTGAATATACTGCTGCTCAGATTTCTTGTGCCAATGGTGCAAAGCAATCTGTATGTAATGC
GATCCTGGTATTGGTAAATCCGGGTGATGAAGTAATTGTACCGGCTCCTTACTGGGTGAGCTATCCGGAAATGGTGAAGA
TGGCAGAAGGTACTCCTGTCATTGTTTCTGCCGGCATCGAACAAGATTTCAAAATTACTCCGAAACAACTGGAAGCAGCT
ATTACTCCGAAAACAAAAGCATTGATTCTTTGTTCTCCGTCCAACCCCACAGGTTCTGTTTACAGCAAAGAAGAACTGGC
TGGACTGGCAGCCGTGCTGGCTAAGTATCCGCAAGTAGTGGTAATTGCTGACGAGATTTACGAACATATCAATTATATCG
GTGCACATCAGAGCATTGCTCAGTTCCCGGAAATGAAAGAACGTACAGTGATCGTGAACGGTGTATCCAAAGCCTATGCG
ATGACTGGATGGAGAATCGGTTTCATTGCTGGTCCGGAATGGATTGTGAAAGCTTGTAACAAGCTTCAGGGACAATACAC
TTCGGGTCCTTGCTCGGTATCTCAGAAAGCTGCCGAGGCTGCTTACGTAGGTACACAAGAACCGGTGAAAGAAATGCAGA
AGGCATTTGAACGTCGTCGTGACCTGATCGTGAAGTTGGCTAAAGAAGTGCCGGGTTTCGAAGTAAACGTACCGCAAGGT
GCTTTCTATCTGTTCCCGAAATGTAGCTACTTCTTCGGCAAGAGCAACGGCGAACGTAAAATTGAAAACTCGGACGACTT
GGCAATGTACCTGCTCGAAGATGCTCATGTAGCTTGTGTAGGCGGTACTTCCTTTGGTGCTCCTGAATGTATTCGTATGA
GCTACGCTACAAGTGATGAGAACATTGTAGAAGCTATCCGTCGAATCAAGGAAGCATTGGCTAAATTGAAATAA

Upstream 100 bases:

>100_bases
TTACATTTTAATAAGTAAAATGCCATTTTGTTTTCATATATCGAATATTATCGCTTATTTTGCAACGAATTTCACTCAAC
AACAATAAAATAGATACAAA

Downstream 100 bases:

>100_bases
GCAATCTTAGAGAATATAGAACGGTAGGCTATCTCCTGAAAAAGAAAGTCTACCGTTTTTTTATGTAATTTCCTTTTGTC
CGTAGCGATAAAATAAAAAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNQLSDRLNSLSPSATLAMSQKSNELKAQGIDVINLSVGEPDFNTPDHIKEAAKKAIDDNFSRYSPVPGYPALRNAIVEK
LKKENGLEYTAAQISCANGAKQSVCNAILVLVNPGDEVIVPAPYWVSYPEMVKMAEGTPVIVSAGIEQDFKITPKQLEAA
ITPKTKALILCSPSNPTGSVYSKEELAGLAAVLAKYPQVVVIADEIYEHINYIGAHQSIAQFPEMKERTVIVNGVSKAYA
MTGWRIGFIAGPEWIVKACNKLQGQYTSGPCSVSQKAAEAAYVGTQEPVKEMQKAFERRRDLIVKLAKEVPGFEVNVPQG
AFYLFPKCSYFFGKSNGERKIENSDDLAMYLLEDAHVACVGGTSFGAPECIRMSYATSDENIVEAIRRIKEALAKLK

Sequences:

>Translated_397_residues
MNQLSDRLNSLSPSATLAMSQKSNELKAQGIDVINLSVGEPDFNTPDHIKEAAKKAIDDNFSRYSPVPGYPALRNAIVEK
LKKENGLEYTAAQISCANGAKQSVCNAILVLVNPGDEVIVPAPYWVSYPEMVKMAEGTPVIVSAGIEQDFKITPKQLEAA
ITPKTKALILCSPSNPTGSVYSKEELAGLAAVLAKYPQVVVIADEIYEHINYIGAHQSIAQFPEMKERTVIVNGVSKAYA
MTGWRIGFIAGPEWIVKACNKLQGQYTSGPCSVSQKAAEAAYVGTQEPVKEMQKAFERRRDLIVKLAKEVPGFEVNVPQG
AFYLFPKCSYFFGKSNGERKIENSDDLAMYLLEDAHVACVGGTSFGAPECIRMSYATSDENIVEAIRRIKEALAKLK
>Mature_397_residues
MNQLSDRLNSLSPSATLAMSQKSNELKAQGIDVINLSVGEPDFNTPDHIKEAAKKAIDDNFSRYSPVPGYPALRNAIVEK
LKKENGLEYTAAQISCANGAKQSVCNAILVLVNPGDEVIVPAPYWVSYPEMVKMAEGTPVIVSAGIEQDFKITPKQLEAA
ITPKTKALILCSPSNPTGSVYSKEELAGLAAVLAKYPQVVVIADEIYEHINYIGAHQSIAQFPEMKERTVIVNGVSKAYA
MTGWRIGFIAGPEWIVKACNKLQGQYTSGPCSVSQKAAEAAYVGTQEPVKEMQKAFERRRDLIVKLAKEVPGFEVNVPQG
AFYLFPKCSYFFGKSNGERKIENSDDLAMYLLEDAHVACVGGTSFGAPECIRMSYATSDENIVEAIRRIKEALAKLK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=362, Percent_Identity=31.2154696132597, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI56713256, Length=319, Percent_Identity=33.2288401253918, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI95147551, Length=322, Percent_Identity=32.6086956521739, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI169881279, Length=322, Percent_Identity=32.6086956521739, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI169881281, Length=319, Percent_Identity=29.4670846394984, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=27.0053475935829, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI149944424, Length=250, Percent_Identity=26, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=27.0777479892761, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1788722, Length=397, Percent_Identity=30.9823677581864, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788627, Length=363, Percent_Identity=29.2011019283747, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=28.0748663101604, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=324, Percent_Identity=27.1604938271605, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=395, Percent_Identity=25.5696202531646, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=395, Percent_Identity=25.5696202531646, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=398, Percent_Identity=27.1356783919598, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573069, Length=321, Percent_Identity=28.0373831775701, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646114, Length=321, Percent_Identity=28.0373831775701, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573067, Length=321, Percent_Identity=28.0373831775701, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573065, Length=321, Percent_Identity=28.0373831775701, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=24.869109947644, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43280; Mature: 43280

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLSDRLNSLSPSATLAMSQKSNELKAQGIDVINLSVGEPDFNTPDHIKEAAKKAIDDN
CCHHHHHHHCCCCCCEEEECCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCC
FSRYSPVPGYPALRNAIVEKLKKENGLEYTAAQISCANGAKQSVCNAILVLVNPGDEVIV
CHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHCEEEEEEECCCCCEEE
PAPYWVSYPEMVKMAEGTPVIVSAGIEQDFKITPKQLEAAITPKTKALILCSPSNPTGSV
CCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHEECCCCCEEEEECCCCCCCCC
YSKEELAGLAAVLAKYPQVVVIADEIYEHINYIGAHQSIAQFPEMKERTVIVNGVSKAYA
CCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHCCCCCCCEEEEECCHHHHH
MTGWRIGFIAGPEWIVKACNKLQGQYTSGPCSVSQKAAEAAYVGTQEPVKEMQKAFERRR
HCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DLIVKLAKEVPGFEVNVPQGAFYLFPKCSYFFGKSNGERKIENSDDLAMYLLEDAHVACV
HHHHHHHHHCCCCEEECCCCCEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCEEEE
GGTSFGAPECIRMSYATSDENIVEAIRRIKEALAKLK
CCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQLSDRLNSLSPSATLAMSQKSNELKAQGIDVINLSVGEPDFNTPDHIKEAAKKAIDDN
CCHHHHHHHCCCCCCEEEECCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCC
FSRYSPVPGYPALRNAIVEKLKKENGLEYTAAQISCANGAKQSVCNAILVLVNPGDEVIV
CHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHCEEEEEEECCCCCEEE
PAPYWVSYPEMVKMAEGTPVIVSAGIEQDFKITPKQLEAAITPKTKALILCSPSNPTGSV
CCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHEECCCCCEEEEECCCCCCCCC
YSKEELAGLAAVLAKYPQVVVIADEIYEHINYIGAHQSIAQFPEMKERTVIVNGVSKAYA
CCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHCCCCCCCEEEEECCHHHHH
MTGWRIGFIAGPEWIVKACNKLQGQYTSGPCSVSQKAAEAAYVGTQEPVKEMQKAFERRR
HCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DLIVKLAKEVPGFEVNVPQGAFYLFPKCSYFFGKSNGERKIENSDDLAMYLLEDAHVACV
HHHHHHHHHCCCCEEECCCCCEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCEEEE
GGTSFGAPECIRMSYATSDENIVEAIRRIKEALAKLK
CCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA