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The map label for this gene is lysA [H]

Identifier: 29346784

GI number: 29346784

Start: 1702211

End: 1703371

Strand: Reverse

Name: lysA [H]

Synonym: BT_1374

Alternate gene names: 29346784

Gene position: 1703371-1702211 (Counterclockwise)

Preceding gene: 29346785

Following gene: 29346783

Centisome position: 27.21

GC content: 47.8

Gene sequence:

>1161_bases
ATGAAAGGAATATTTCCAATCGATAAATTCCGTACTTTGCAGACACCTTTCTATTATTATGATACGAAAGTGCTGCGTGA
TACATTGTCGGCTATTAACCAAGAGGTTGCCAAATATCCTAGCTATTCCGTACATTATGCCGTGAAGGCGAATGCCAATC
CGAAAGTACTTACCATTATCCGTGAAAGCGGAATGGGAGCAGACTGCGTGAGTGGCGGAGAAATCCGTGCCGCTGTCCGT
GCCGGATTCCCTGCCAATAAAATCGTTTTTGCCGGAGTCGGGAAAGCGGATTGGGAGATCAACCTCGGACTGGAATATGG
CATCTTCTGTTTCAATGTAGAGTCTATCCCCGAACTGGAAGTCATCAACGAACTGGCTGCCGCTCAAAATAAGATCGCTA
ATGTCGCTTTCCGTATCAATCCGGATGTCGGGGCGCATACGCACGCCAATATCACCACCGGTCTGGCTGAAAACAAATTC
GGTATCAGTATGCAGGACATGGACAGGGTGATCGATGTGGCTTTGGAAATGAAGAATGTAAAATTCATCGGTCTGCACTT
CCATATCGGTTCGCAGATATTGGATATGGGCGATTTCATCGCTCTTTGTAACCGGGTGAATGAATTGCAGGACAAGCTCG
AAGCCCGCCGTATTCTGGTAGAGCATATCAATGTCGGTGGTGGTCTGGGCATTGACTACGGTCATCCTAACCGCCAGTCC
GTTCCGGACTTCAAAAGCTATTTTGCTACCTATGCCGGACAGCTGAAACTGCGTCCTTATCAGACATTGCACTTTGAATT
GGGACGTGCGGTGGTAGGACAGTGCGGCTCTCTGATATCGAAAGTGCTGTATGTAAAGCAGGGAACGAAGAAGAAATTTG
CCATCCTCGATGCAGGTATGACAGACTTGATTCGTCCGGCTTTGTATCAGGCTTACCACAAGATGGAAAACATCACTTCA
GAAGAACCTGTAGAGGCTTATGACGTAGTAGGTCCGATCTGTGAATCATCAGACGTTTTCGGTAAAGCGATTGACCTGAA
CAAAGTGAAGCGGGGAGACCTGATTGCACTTCGTTCCGCAGGTGCCTATGGTGAGATTATGGCATCCGGATACAACTGTC
GTGAACTGCCGAAAGGATACACTTCGGACGAGCTGGTGTAA

Upstream 100 bases:

>100_bases
TATGCTTTTCAACAACAAATAATTCCACAAATAATACGAGCGCTTTTATTGATACTGATAAAAGCGCTCTTTTTAACTAA
CTAAACAAGTTTCTTGAATT

Downstream 100 bases:

>100_bases
ATAAAATGTGAATGTAGTTTAAAAATGCAGGGAGCTTGGAACAATTTTAACTGAAATCTTGTTATTTTTGTAATGAGTTC
AAAAGAAAACTACATTAACA

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKGIFPIDKFRTLQTPFYYYDTKVLRDTLSAINQEVAKYPSYSVHYAVKANANPKVLTIIRESGMGADCVSGGEIRAAVR
AGFPANKIVFAGVGKADWEINLGLEYGIFCFNVESIPELEVINELAAAQNKIANVAFRINPDVGAHTHANITTGLAENKF
GISMQDMDRVIDVALEMKNVKFIGLHFHIGSQILDMGDFIALCNRVNELQDKLEARRILVEHINVGGGLGIDYGHPNRQS
VPDFKSYFATYAGQLKLRPYQTLHFELGRAVVGQCGSLISKVLYVKQGTKKKFAILDAGMTDLIRPALYQAYHKMENITS
EEPVEAYDVVGPICESSDVFGKAIDLNKVKRGDLIALRSAGAYGEIMASGYNCRELPKGYTSDELV

Sequences:

>Translated_386_residues
MKGIFPIDKFRTLQTPFYYYDTKVLRDTLSAINQEVAKYPSYSVHYAVKANANPKVLTIIRESGMGADCVSGGEIRAAVR
AGFPANKIVFAGVGKADWEINLGLEYGIFCFNVESIPELEVINELAAAQNKIANVAFRINPDVGAHTHANITTGLAENKF
GISMQDMDRVIDVALEMKNVKFIGLHFHIGSQILDMGDFIALCNRVNELQDKLEARRILVEHINVGGGLGIDYGHPNRQS
VPDFKSYFATYAGQLKLRPYQTLHFELGRAVVGQCGSLISKVLYVKQGTKKKFAILDAGMTDLIRPALYQAYHKMENITS
EEPVEAYDVVGPICESSDVFGKAIDLNKVKRGDLIALRSAGAYGEIMASGYNCRELPKGYTSDELV
>Mature_386_residues
MKGIFPIDKFRTLQTPFYYYDTKVLRDTLSAINQEVAKYPSYSVHYAVKANANPKVLTIIRESGMGADCVSGGEIRAAVR
AGFPANKIVFAGVGKADWEINLGLEYGIFCFNVESIPELEVINELAAAQNKIANVAFRINPDVGAHTHANITTGLAENKF
GISMQDMDRVIDVALEMKNVKFIGLHFHIGSQILDMGDFIALCNRVNELQDKLEARRILVEHINVGGGLGIDYGHPNRQS
VPDFKSYFATYAGQLKLRPYQTLHFELGRAVVGQCGSLISKVLYVKQGTKKKFAILDAGMTDLIRPALYQAYHKMENITS
EEPVEAYDVVGPICESSDVFGKAIDLNKVKRGDLIALRSAGAYGEIMASGYNCRELPKGYTSDELV

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=390, Percent_Identity=31.2820512820513, Blast_Score=151, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 42574; Mature: 42574

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIFPIDKFRTLQTPFYYYDTKVLRDTLSAINQEVAKYPSYSVHYAVKANANPKVLTII
CCCCCCCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEE
RESGMGADCVSGGEIRAAVRAGFPANKIVFAGVGKADWEINLGLEYGIFCFNVESIPELE
ECCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECEEEEEEEEECCCCCHHH
VINELAAAQNKIANVAFRINPDVGAHTHANITTGLAENKFGISMQDMDRVIDVALEMKNV
HHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCE
KFIGLHFHIGSQILDMGDFIALCNRVNELQDKLEARRILVEHINVGGGLGIDYGHPNRQS
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VPDFKSYFATYAGQLKLRPYQTLHFELGRAVVGQCGSLISKVLYVKQGTKKKFAILDAGM
CCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCH
TDLIRPALYQAYHKMENITSEEPVEAYDVVGPICESSDVFGKAIDLNKVKRGDLIALRSA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEECC
GAYGEIMASGYNCRELPKGYTSDELV
CCCHHHHHCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MKGIFPIDKFRTLQTPFYYYDTKVLRDTLSAINQEVAKYPSYSVHYAVKANANPKVLTII
CCCCCCCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEE
RESGMGADCVSGGEIRAAVRAGFPANKIVFAGVGKADWEINLGLEYGIFCFNVESIPELE
ECCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECEEEEEEEEECCCCCHHH
VINELAAAQNKIANVAFRINPDVGAHTHANITTGLAENKFGISMQDMDRVIDVALEMKNV
HHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCE
KFIGLHFHIGSQILDMGDFIALCNRVNELQDKLEARRILVEHINVGGGLGIDYGHPNRQS
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VPDFKSYFATYAGQLKLRPYQTLHFELGRAVVGQCGSLISKVLYVKQGTKKKFAILDAGM
CCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCH
TDLIRPALYQAYHKMENITSEEPVEAYDVVGPICESSDVFGKAIDLNKVKRGDLIALRSA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEECC
GAYGEIMASGYNCRELPKGYTSDELV
CCCHHHHHCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]