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The map label for this gene is htpG

Identifier: 29346307

GI number: 29346307

Start: 1102658

End: 1104703

Strand: Reverse

Name: htpG

Synonym: BT_0897

Alternate gene names: 29346307

Gene position: 1104703-1102658 (Counterclockwise)

Preceding gene: 29346308

Following gene: 29346306

Centisome position: 17.65

GC content: 38.81

Gene sequence:

>2046_bases
ATGCAAAAAGGTAATATTGGGGTTACAACAGAGAACATTTTCCCTATCATCAAAAAGTTCTTGTACAGTGACCATGAAAT
TTTTCTTCGCGAATTAGTGTCTAACGCAGTAGATGCCACTCAGAAACTGAATACCCTTGCTTCCATTGGAGAGTTTAAAG
GTGAACTGGGCGATCTGACAATTCACGTTGAATTAGGTAAAGACACTATTACTATCTCCGACCGTGGTATTGGTCTGACT
GCAGAAGAAATAGAAAAGTACATTAATCAGATTGCATTTTCAGGAGCAAATGATTTTCTGGAAAAATACAAAGATGATGC
AAATGCAATCATCGGACATTTCGGTTTAGGCTTCTATTCTGCCTTTATGGTTGCAAAAAAGGTTGAAATTATCACCAAAT
CCTACAGAGACGAAGCACAAGCTATAAAATGGACTTGTGATGGTAGCCCTGAATTCACTATTGAAGAAGTAGATAAGGCA
GATCGTGGTTCAGATATCATCTTATATATCGATGACGATTGCAAAGAATTCCTCGAAGAAGCACGTGTTTCTGAGCTTCT
GAAGAAATATTGCAGCTTCCTTCCTGTCCCCATTGCATTCGGAAAAAAGAAAGAATGGAAAGATGGCAAACAGATAGAAA
CCACTGAAGACAATATTATTAACGATACCACTCCATTGTGGACTCGTAAGCCGAGCGAACTGTCGGACGAGGATTATAAG
TCGTTCTATACCAAGTTGTACCCGATGTCAGACGAGCCATTATTTTGGATTCATCTGAATGTAGATTACCCGTTCCATCT
GACCGGTATCCTCTATTTCCCGAAAGTAAAGAGCAATATTGAGCTGAATAAAAATAAGATTCAATTATATTGCAACCAAG
TATATGTAACGGATTCTGTAGAAGGAATTGTACCGGACTTCTTGACTTTATTACATGGAGTTATTGATTCTCCGGATATT
CCATTGAATGTATCCCGTTCTTATTTGCAAAGCGACTCGAATGTGAAGAAGATTTCTACCTATATCACAAAGAAAGTTTC
CGATCGCCTGCAATCGATTTTCAAGAACGACCGCAAACAGTTTGAAGAGAAGTGGAATGATTTGAAAATATTTATCAATT
ACGGCATGCTTACTCAAGAGGATTTCTATGAGAAAGCGCAAAAATTCGCCCTTTTCACCGATACAGATAACAAACATTAT
ACATTTGAAGAGTATCAGACCCTTATTAAAGATAATCAGACAGACAAAGATGGAAATCTGATCTATTTGTATGCTAATAA
TAAGGATGAACAATTCAGTTATATCGAGGCTGCCACCAACAAGGGGTACAATGTTCTGCTTATGGATGGTCAATTAGATG
TAGCTATGGTAAGTATGTTGGAACAGAAGTTTGAGAAATCTCGCTTCACCCGTGTAGACAGCGATGTTATCGACAACCTT
ATCATCAAAGAAGACAAGAAAAACGAGACATTGGAAGGAGAAAAGCAAGAAGCTATCACAACTGCTTTCAAGAGCCAATT
GCCCAAAATGGATAAAGTTGAGTTCAATGTAATGACACAGGCATTGGGAGACAATTCAGCTCCGGTGATGATTACTCAAA
GCGAATATATGCGTCGTATGAAGGAAATGGCAAATATTCAGGCCGGAATGAGCTTCTATGGAGAGATGCCGGATATGTTC
AATCTGGTTCTGAACTCCGACCATAAGCTTATCAAGCAAGTGCTTGACGAAGAAGAAGCAGCTTGTCACCCTGAAGTAGC
TCCTATACAAACAGAGATGAATAGTGTCAGCAAGCGTCGCAATGAACTAAAAGACAGCCAAAAAGACAAGAAGGAAGAAG
ATATTCCTACTGCAGAGAAAGATGAATTGAATGAGCTGGATAAAAAATGGGATGAACTGAAAAATAAAAAAGAAGGCATC
TTTGCAGGATATGCCAGCAACAACAAGGTAATCCGTCAACTCATCGACCTGGCTTTATTGCAAAACAATATGCTAAAAGG
TGAAGCTCTGAACAACTTCGTGAAGCGCAGTATTGAGCTGATTTAA

Upstream 100 bases:

>100_bases
AGAATGTCAGACCTTAGGGTCTGGCATTTTTTTTGTCTCTATCTGAACAAATATCAATTAAAAACATTCTAATAAATAAA
CCAAAAAAATATACGTTATT

Downstream 100 bases:

>100_bases
TACCGCCCCTTTATTTATAACATAAATCAATGAAAGAGCATTCAACACTAAAACGTGTTGCAATGCTCTTTTTTCATCAT
AAAACGAACGCTAAAATATC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLNTLASIGEFKGELGDLTIHVELGKDTITISDRGIGLT
AEEIEKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYSAFMVAKKVEIITKSYRDEAQAIKWTCDGSPEFTIEEVDKA
DRGSDIILYIDDDCKEFLEEARVSELLKKYCSFLPVPIAFGKKKEWKDGKQIETTEDNIINDTTPLWTRKPSELSDEDYK
SFYTKLYPMSDEPLFWIHLNVDYPFHLTGILYFPKVKSNIELNKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVIDSPDI
PLNVSRSYLQSDSNVKKISTYITKKVSDRLQSIFKNDRKQFEEKWNDLKIFINYGMLTQEDFYEKAQKFALFTDTDNKHY
TFEEYQTLIKDNQTDKDGNLIYLYANNKDEQFSYIEAATNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDNL
IIKEDKKNETLEGEKQEAITTAFKSQLPKMDKVEFNVMTQALGDNSAPVMITQSEYMRRMKEMANIQAGMSFYGEMPDMF
NLVLNSDHKLIKQVLDEEEAACHPEVAPIQTEMNSVSKRRNELKDSQKDKKEEDIPTAEKDELNELDKKWDELKNKKEGI
FAGYASNNKVIRQLIDLALLQNNMLKGEALNNFVKRSIELI

Sequences:

>Translated_681_residues
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLNTLASIGEFKGELGDLTIHVELGKDTITISDRGIGLT
AEEIEKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYSAFMVAKKVEIITKSYRDEAQAIKWTCDGSPEFTIEEVDKA
DRGSDIILYIDDDCKEFLEEARVSELLKKYCSFLPVPIAFGKKKEWKDGKQIETTEDNIINDTTPLWTRKPSELSDEDYK
SFYTKLYPMSDEPLFWIHLNVDYPFHLTGILYFPKVKSNIELNKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVIDSPDI
PLNVSRSYLQSDSNVKKISTYITKKVSDRLQSIFKNDRKQFEEKWNDLKIFINYGMLTQEDFYEKAQKFALFTDTDNKHY
TFEEYQTLIKDNQTDKDGNLIYLYANNKDEQFSYIEAATNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDNL
IIKEDKKNETLEGEKQEAITTAFKSQLPKMDKVEFNVMTQALGDNSAPVMITQSEYMRRMKEMANIQAGMSFYGEMPDMF
NLVLNSDHKLIKQVLDEEEAACHPEVAPIQTEMNSVSKRRNELKDSQKDKKEEDIPTAEKDELNELDKKWDELKNKKEGI
FAGYASNNKVIRQLIDLALLQNNMLKGEALNNFVKRSIELI
>Mature_681_residues
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLNTLASIGEFKGELGDLTIHVELGKDTITISDRGIGLT
AEEIEKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYSAFMVAKKVEIITKSYRDEAQAIKWTCDGSPEFTIEEVDKA
DRGSDIILYIDDDCKEFLEEARVSELLKKYCSFLPVPIAFGKKKEWKDGKQIETTEDNIINDTTPLWTRKPSELSDEDYK
SFYTKLYPMSDEPLFWIHLNVDYPFHLTGILYFPKVKSNIELNKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVIDSPDI
PLNVSRSYLQSDSNVKKISTYITKKVSDRLQSIFKNDRKQFEEKWNDLKIFINYGMLTQEDFYEKAQKFALFTDTDNKHY
TFEEYQTLIKDNQTDKDGNLIYLYANNKDEQFSYIEAATNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDNL
IIKEDKKNETLEGEKQEAITTAFKSQLPKMDKVEFNVMTQALGDNSAPVMITQSEYMRRMKEMANIQAGMSFYGEMPDMF
NLVLNSDHKLIKQVLDEEEAACHPEVAPIQTEMNSVSKRRNELKDSQKDKKEEDIPTAEKDELNELDKKWDELKNKKEGI
FAGYASNNKVIRQLIDLALLQNNMLKGEALNNFVKRSIELI

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI155722983, Length=598, Percent_Identity=29.0969899665552, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI4507677, Length=637, Percent_Identity=27.4725274725275, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI154146191, Length=198, Percent_Identity=36.8686868686869, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI153792590, Length=195, Percent_Identity=38.4615384615385, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI20149594, Length=197, Percent_Identity=37.5634517766497, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI1786679, Length=592, Percent_Identity=32.2635135135135, Blast_Score=263, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI115535205, Length=468, Percent_Identity=30.5555555555556, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI115535167, Length=416, Percent_Identity=31.4903846153846, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17542208, Length=615, Percent_Identity=29.2682926829268, Blast_Score=203, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17559162, Length=619, Percent_Identity=27.9483037156704, Blast_Score=202, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6325016, Length=601, Percent_Identity=29.1181364392679, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6323840, Length=596, Percent_Identity=29.0268456375839, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24586016, Length=492, Percent_Identity=32.9268292682927, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI21357739, Length=518, Percent_Identity=32.4324324324324, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI17647529, Length=630, Percent_Identity=26.031746031746, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_BACTN (Q8A9B8)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_809810.1
- ProteinModelPortal:   Q8A9B8
- GeneID:   1073986
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0897
- NMPDR:   fig|226186.1.peg.897
- HOGENOM:   HBG286705
- OMA:   KFLYSDH
- ProtClustDB:   PRK05218
- BioCyc:   BTHE226186:BT_0897-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 78438; Mature: 78438

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLNTLASIGEFKGELGDLT
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IHVELGKDTITISDRGIGLTAEEIEKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYS
EEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
AFMVAKKVEIITKSYRDEAQAIKWTCDGSPEFTIEEVDKADRGSDIILYIDDDCKEFLEE
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHCCCCCCCEEEEEECCHHHHHHHH
ARVSELLKKYCSFLPVPIAFGKKKEWKDGKQIETTEDNIINDTTPLWTRKPSELSDEDYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHH
SFYTKLYPMSDEPLFWIHLNVDYPFHLTGILYFPKVKSNIELNKNKIQLYCNQVYVTDSV
HHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCEECCCEEEEEEEEEEEECCC
EGIVPDFLTLLHGVIDSPDIPLNVSRSYLQSDSNVKKISTYITKKVSDRLQSIFKNDRKQ
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEKWNDLKIFINYGMLTQEDFYEKAQKFALFTDTDNKHYTFEEYQTLIKDNQTDKDGNL
HHHHCCCEEEEEECCCCCHHHHHHHHHHEEEEECCCCCCEEHHHHHHHHHCCCCCCCCCE
IYLYANNKDEQFSYIEAATNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDNL
EEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIKEDKKNETLEGEKQEAITTAFKSQLPKMDKVEFNVMTQALGDNSAPVMITQSEYMRRM
HCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHH
KEMANIQAGMSFYGEMPDMFNLVLNSDHKLIKQVLDEEEAACHPEVAPIQTEMNSVSKRR
HHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHH
NELKDSQKDKKEEDIPTAEKDELNELDKKWDELKNKKEGIFAGYASNNKVIRQLIDLALL
HHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
QNNMLKGEALNNFVKRSIELI
HCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLNTLASIGEFKGELGDLT
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IHVELGKDTITISDRGIGLTAEEIEKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYS
EEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
AFMVAKKVEIITKSYRDEAQAIKWTCDGSPEFTIEEVDKADRGSDIILYIDDDCKEFLEE
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHCCCCCCCEEEEEECCHHHHHHHH
ARVSELLKKYCSFLPVPIAFGKKKEWKDGKQIETTEDNIINDTTPLWTRKPSELSDEDYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHH
SFYTKLYPMSDEPLFWIHLNVDYPFHLTGILYFPKVKSNIELNKNKIQLYCNQVYVTDSV
HHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCEECCCEEEEEEEEEEEECCC
EGIVPDFLTLLHGVIDSPDIPLNVSRSYLQSDSNVKKISTYITKKVSDRLQSIFKNDRKQ
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEKWNDLKIFINYGMLTQEDFYEKAQKFALFTDTDNKHYTFEEYQTLIKDNQTDKDGNL
HHHHCCCEEEEEECCCCCHHHHHHHHHHEEEEECCCCCCEEHHHHHHHHHCCCCCCCCCE
IYLYANNKDEQFSYIEAATNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDNL
EEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIKEDKKNETLEGEKQEAITTAFKSQLPKMDKVEFNVMTQALGDNSAPVMITQSEYMRRM
HCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHH
KEMANIQAGMSFYGEMPDMFNLVLNSDHKLIKQVLDEEEAACHPEVAPIQTEMNSVSKRR
HHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHH
NELKDSQKDKKEEDIPTAEKDELNELDKKWDELKNKKEGIFAGYASNNKVIRQLIDLALL
HHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
QNNMLKGEALNNFVKRSIELI
HCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928