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The map label for this gene is clpC [H]

Identifier: 29346308

GI number: 29346308

Start: 1104843

End: 1107368

Strand: Reverse

Name: clpC [H]

Synonym: BT_0898

Alternate gene names: 29346308

Gene position: 1107368-1104843 (Counterclockwise)

Preceding gene: 29346311

Following gene: 29346307

Centisome position: 17.69

GC content: 42.16

Gene sequence:

>2526_bases
ATGAATAATCAATTCTCACAAAGAGTTTCCGACATTATCGTCTATAGCAAGGAAGAAGCTAACCGGTTGAGGAGTAGGCA
TATCGGACCTGAGCACCTACTTCTGGGAATGCTTCGTGACGGTGAAGGAAAAGCTATCGAGATATTGTCAAAACTCAACA
CCAATTTAGCTGCAGTAAAGCAGCAGATTGAAGCTCGGCTGAAGACAGAAGCTGATGATATGCTATTGCCTGATGCAGAG
ATACCGTTGTCTAATGACGCGGCAAAAATATTAAAAATGTGTATTTTAGAAGCACGTGGAATGAAAAGTAATATAGCTGA
TACAGAGCATGTTTTGTTAGCGATCCTAAGAGAAAGAAACAATATGGCTGCTTCCGTGCTCGAAGCTAATGACGTTAATT
ACGTGAAAGTGTTGGAACAAGCCACATTGCAACCGGATGTAAATTCCGGTATGGGATTTCCGGAAGACGATGATGATGAA
GAAATGTCTTCTCCCCGATCTGGTGGAAGCGGTTCTGAAGAACGCCAGCAACAGGCGCAAACAGCTTCAAAAAAACCGGC
CAATGACACGCCTGTACTTGACAATTTCGGTACAGATATGACAAAAGCGGCAGAAGAAGGACGTTTGGACCCTGTGGTAG
GCAGAGAAAAGGAAATTGAACGCTTGGCTCAAATTCTGAGTCGCCGCAAAAAGAACAATCCGATTCTGATCGGTGAACCT
GGTGTAGGAAAATCAGCAATCGTTGAAGGACTAGCTTTGAGAATTATTCAAAAGAAAGTCTCACGCATCTTGTTTGATAA
GCGAGTAGTAGCTCTTGACATGACCGCAGTTGTGGCAGGAACAAAATACCGTGGTCAGTTTGAAGAGCGTATTCGTTCCA
TTCTCAACGAGTTACAAAGGAATCCGAATGTGATCCTGTTCATTGATGAGATCCATACAATTGTAGGTGCAGGTTCTGCA
GCCGGTTCAATGGATGCAGCCAATATGCTGAAACCTGCATTGGCACGCGGCGAAATACAATGTATTGGTGCTACTACCCT
TGATGAATACCGTAAGAATATAGAAAAAGACGGTGCTTTGGAACGTCGTTTCCAAAAAGTTATGGTGGAACCCACTACTG
CTGCCGAAACTCTTCAGATTCTGCGTAACATCAAGGATAAATATGAAGATCATCATAACGTGAACTATACAGATGAAGCA
TTGGAAGCTTGTGTCAAGTTGACAGACCGTTATATTACGGACCGTAACTTCCCTGATAAAGCTATTGACGCTTTGGATGA
AGCAGGATCACGTGTACATCTGACCAACGTCAATGTGCCCAAGGAAATCGAAGAGCAGGAAAAACTCATCGAAGAAGCTA
AAAGCAAGAAAAATGAAGCTGTGAAATCGCAAAATTTTGAACTCGCTGCCAGTTTCCGAGATAAGGAGAAAGAGCTTACG
CTTCAGTTGGACGAAATGAAACGGGAATGGGAAAACAGCCTGAAAGAGAACAGACAGACTGTTGATGCAGAGGAAATTGC
CAATGTTATTTCTATGATGTCCGGCATTCCGGTACAGCGTATGGCGCAAGCCGAAGGAATTAAGCTAGCCGGCATGAAGG
AGGATCTGCAATCGAAAGTGATCGCACAAGATCCGGCTATAGAGAAACTGGTTAAAGCTATTTTAAGAAGCCGTGTGGGA
TTGAAGGATCCCAATAAGCCCATTGGAACCTTTATGTTCTTAGGCCCGACTGGTGTAGGTAAAACCCATTTAGCCAAAGA
ATTGGCAAAATATATGTTCGGCTCTTCCGATGCACTGATTCGTATAGACATGAGCGAATTTATGGAAAAATTCACTGTCT
CACGTCTGGTCGGAGCTCCTCCGGGATATGTAGGATATGAAGAAGGCGGACAATTAACTGAAAAAGTACGTCGCAAACCT
TATTCTATCGTCTTGCTTGATGAGATCGAAAAAGCACATCCGGATGTGTTCAATCTCCTTCTTCAAGTGATGGACGAAGG
CCGTCTAACTGACAGTTATGGCAGAATGGTTGATTTTAAAAATACAGTTATTATCATGACTTCCAATATTGGCACCCGCC
AGTTAAAGGAGTTTGGACGTGGTGTAGGATTTGCTACACAAAGCCGTCTGGATGATAAAGAGTTCTCGCGAAGTGTTATA
CAAAAAGCATTAAATAAATCATTCGCGCCAGAATTTATCAATCGTGTCGATGAAATCATAACATTTGACCAACTCTCTTT
GGAAGCTATCACGAAAATCATTGATATTGAGCTAAAAGGACTATATGATCGTATTGAATCTATTGGATATAAGCTAGTTA
TTGATGATGAAGCAAAAAGATTTGTGGCCGAAAAAGGATACGACGTGCAATTCGGAGCCCGCCCTTTAAAACGAGCTATT
CAAACTCATCTAGAGGATGGACTGTCAGAACTCATTATAACTTCTTCTCTGAAAGAAAAAGATGTCATTCAAGTCTCTCT
GAATAAAGAGAAAGGTGAATTGGAGATGAAAGTTATTGCATCTTGA

Upstream 100 bases:

>100_bases
GCCATTTGTAGATATAAGAAATAAAGCAAATATGCAATACAAACTTGATTAAATACGTATATTTGCCAGTAAATAACCCC
TTAGAAGAAAAGGAAAAAGT

Downstream 100 bases:

>100_bases
AAGAAGATTGCTTAAATAAGATAAGTTATAAAATATGCCAGAATGTCAGACCTTAGGGTCTGGCATTTTTTTTGTCTCTA
TCTGAACAAATATCAATTAA

Product: ATP-dependent Clp protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 841; Mature: 841

Protein sequence:

>841_residues
MNNQFSQRVSDIIVYSKEEANRLRSRHIGPEHLLLGMLRDGEGKAIEILSKLNTNLAAVKQQIEARLKTEADDMLLPDAE
IPLSNDAAKILKMCILEARGMKSNIADTEHVLLAILRERNNMAASVLEANDVNYVKVLEQATLQPDVNSGMGFPEDDDDE
EMSSPRSGGSGSEERQQQAQTASKKPANDTPVLDNFGTDMTKAAEEGRLDPVVGREKEIERLAQILSRRKKNNPILIGEP
GVGKSAIVEGLALRIIQKKVSRILFDKRVVALDMTAVVAGTKYRGQFEERIRSILNELQRNPNVILFIDEIHTIVGAGSA
AGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVMVEPTTAAETLQILRNIKDKYEDHHNVNYTDEA
LEACVKLTDRYITDRNFPDKAIDALDEAGSRVHLTNVNVPKEIEEQEKLIEEAKSKKNEAVKSQNFELAASFRDKEKELT
LQLDEMKREWENSLKENRQTVDAEEIANVISMMSGIPVQRMAQAEGIKLAGMKEDLQSKVIAQDPAIEKLVKAILRSRVG
LKDPNKPIGTFMFLGPTGVGKTHLAKELAKYMFGSSDALIRIDMSEFMEKFTVSRLVGAPPGYVGYEEGGQLTEKVRRKP
YSIVLLDEIEKAHPDVFNLLLQVMDEGRLTDSYGRMVDFKNTVIIMTSNIGTRQLKEFGRGVGFATQSRLDDKEFSRSVI
QKALNKSFAPEFINRVDEIITFDQLSLEAITKIIDIELKGLYDRIESIGYKLVIDDEAKRFVAEKGYDVQFGARPLKRAI
QTHLEDGLSELIITSSLKEKDVIQVSLNKEKGELEMKVIAS

Sequences:

>Translated_841_residues
MNNQFSQRVSDIIVYSKEEANRLRSRHIGPEHLLLGMLRDGEGKAIEILSKLNTNLAAVKQQIEARLKTEADDMLLPDAE
IPLSNDAAKILKMCILEARGMKSNIADTEHVLLAILRERNNMAASVLEANDVNYVKVLEQATLQPDVNSGMGFPEDDDDE
EMSSPRSGGSGSEERQQQAQTASKKPANDTPVLDNFGTDMTKAAEEGRLDPVVGREKEIERLAQILSRRKKNNPILIGEP
GVGKSAIVEGLALRIIQKKVSRILFDKRVVALDMTAVVAGTKYRGQFEERIRSILNELQRNPNVILFIDEIHTIVGAGSA
AGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVMVEPTTAAETLQILRNIKDKYEDHHNVNYTDEA
LEACVKLTDRYITDRNFPDKAIDALDEAGSRVHLTNVNVPKEIEEQEKLIEEAKSKKNEAVKSQNFELAASFRDKEKELT
LQLDEMKREWENSLKENRQTVDAEEIANVISMMSGIPVQRMAQAEGIKLAGMKEDLQSKVIAQDPAIEKLVKAILRSRVG
LKDPNKPIGTFMFLGPTGVGKTHLAKELAKYMFGSSDALIRIDMSEFMEKFTVSRLVGAPPGYVGYEEGGQLTEKVRRKP
YSIVLLDEIEKAHPDVFNLLLQVMDEGRLTDSYGRMVDFKNTVIIMTSNIGTRQLKEFGRGVGFATQSRLDDKEFSRSVI
QKALNKSFAPEFINRVDEIITFDQLSLEAITKIIDIELKGLYDRIESIGYKLVIDDEAKRFVAEKGYDVQFGARPLKRAI
QTHLEDGLSELIITSSLKEKDVIQVSLNKEKGELEMKVIAS
>Mature_841_residues
MNNQFSQRVSDIIVYSKEEANRLRSRHIGPEHLLLGMLRDGEGKAIEILSKLNTNLAAVKQQIEARLKTEADDMLLPDAE
IPLSNDAAKILKMCILEARGMKSNIADTEHVLLAILRERNNMAASVLEANDVNYVKVLEQATLQPDVNSGMGFPEDDDDE
EMSSPRSGGSGSEERQQQAQTASKKPANDTPVLDNFGTDMTKAAEEGRLDPVVGREKEIERLAQILSRRKKNNPILIGEP
GVGKSAIVEGLALRIIQKKVSRILFDKRVVALDMTAVVAGTKYRGQFEERIRSILNELQRNPNVILFIDEIHTIVGAGSA
AGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVMVEPTTAAETLQILRNIKDKYEDHHNVNYTDEA
LEACVKLTDRYITDRNFPDKAIDALDEAGSRVHLTNVNVPKEIEEQEKLIEEAKSKKNEAVKSQNFELAASFRDKEKELT
LQLDEMKREWENSLKENRQTVDAEEIANVISMMSGIPVQRMAQAEGIKLAGMKEDLQSKVIAQDPAIEKLVKAILRSRVG
LKDPNKPIGTFMFLGPTGVGKTHLAKELAKYMFGSSDALIRIDMSEFMEKFTVSRLVGAPPGYVGYEEGGQLTEKVRRKP
YSIVLLDEIEKAHPDVFNLLLQVMDEGRLTDSYGRMVDFKNTVIIMTSNIGTRQLKEFGRGVGFATQSRLDDKEFSRSVI
QKALNKSFAPEFINRVDEIITFDQLSLEAITKIIDIELKGLYDRIESIGYKLVIDDEAKRFVAEKGYDVQFGARPLKRAI
QTHLEDGLSELIITSSLKEKDVIQVSLNKEKGELEMKVIAS

Specific function: Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat- denatured proteins for degradation by ClpP [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=296, Percent_Identity=35.8108108108108, Blast_Score=190, Evalue=4e-48,
Organism=Escherichia coli, GI1788943, Length=878, Percent_Identity=43.3940774487472, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=822, Percent_Identity=38.5644768856448, Blast_Score=544, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6320464, Length=704, Percent_Identity=41.7613636363636, Blast_Score=532, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6323002, Length=351, Percent_Identity=41.3105413105413, Blast_Score=279, Evalue=1e-75,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 94060; Mature: 94060

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQFSQRVSDIIVYSKEEANRLRSRHIGPEHLLLGMLRDGEGKAIEILSKLNTNLAAVK
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
QQIEARLKTEADDMLLPDAEIPLSNDAAKILKMCILEARGMKSNIADTEHVLLAILRERN
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
NMAASVLEANDVNYVKVLEQATLQPDVNSGMGFPEDDDDEEMSSPRSGGSGSEERQQQAQ
CHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHH
TASKKPANDTPVLDNFGTDMTKAAEEGRLDPVVGREKEIERLAQILSRRKKNNPILIGEP
HHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECC
GVGKSAIVEGLALRIIQKKVSRILFDKRVVALDMTAVVAGTKYRGQFEERIRSILNELQR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCCCCCCHHHHHHHHHHHHHHC
NPNVILFIDEIHTIVGAGSAAGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGAL
CCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCHH
ERRFQKVMVEPTTAAETLQILRNIKDKYEDHHNVNYTDEALEACVKLTDRYITDRNFPDK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
AIDALDEAGSRVHLTNVNVPKEIEEQEKLIEEAKSKKNEAVKSQNFELAASFRDKEKELT
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCHHHH
LQLDEMKREWENSLKENRQTVDAEEIANVISMMSGIPVQRMAQAEGIKLAGMKEDLQSKV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCEECCCHHHHHHHH
IAQDPAIEKLVKAILRSRVGLKDPNKPIGTFMFLGPTGVGKTHLAKELAKYMFGSSDALI
HHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEE
RIDMSEFMEKFTVSRLVGAPPGYVGYEEGGQLTEKVRRKPYSIVLLDEIEKAHPDVFNLL
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHH
LQVMDEGRLTDSYGRMVDFKNTVIIMTSNIGTRQLKEFGRGVGFATQSRLDDKEFSRSVI
HHHHHCCCCCHHHCCEEECCCEEEEEECCCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHH
QKALNKSFAPEFINRVDEIITFDQLSLEAITKIIDIELKGLYDRIESIGYKLVIDDEAKR
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHH
FVAEKGYDVQFGARPLKRAIQTHLEDGLSELIITSSLKEKDVIQVSLNKEKGELEMKVIA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEC
S
C
>Mature Secondary Structure
MNNQFSQRVSDIIVYSKEEANRLRSRHIGPEHLLLGMLRDGEGKAIEILSKLNTNLAAVK
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
QQIEARLKTEADDMLLPDAEIPLSNDAAKILKMCILEARGMKSNIADTEHVLLAILRERN
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
NMAASVLEANDVNYVKVLEQATLQPDVNSGMGFPEDDDDEEMSSPRSGGSGSEERQQQAQ
CHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHH
TASKKPANDTPVLDNFGTDMTKAAEEGRLDPVVGREKEIERLAQILSRRKKNNPILIGEP
HHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECC
GVGKSAIVEGLALRIIQKKVSRILFDKRVVALDMTAVVAGTKYRGQFEERIRSILNELQR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCCCCCCHHHHHHHHHHHHHHC
NPNVILFIDEIHTIVGAGSAAGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGAL
CCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCHH
ERRFQKVMVEPTTAAETLQILRNIKDKYEDHHNVNYTDEALEACVKLTDRYITDRNFPDK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
AIDALDEAGSRVHLTNVNVPKEIEEQEKLIEEAKSKKNEAVKSQNFELAASFRDKEKELT
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCHHHH
LQLDEMKREWENSLKENRQTVDAEEIANVISMMSGIPVQRMAQAEGIKLAGMKEDLQSKV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCEECCCHHHHHHHH
IAQDPAIEKLVKAILRSRVGLKDPNKPIGTFMFLGPTGVGKTHLAKELAKYMFGSSDALI
HHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEE
RIDMSEFMEKFTVSRLVGAPPGYVGYEEGGQLTEKVRRKPYSIVLLDEIEKAHPDVFNLL
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHH
LQVMDEGRLTDSYGRMVDFKNTVIIMTSNIGTRQLKEFGRGVGFATQSRLDDKEFSRSVI
HHHHHCCCCCHHHCCEEECCCEEEEEECCCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHH
QKALNKSFAPEFINRVDEIITFDQLSLEAITKIIDIELKGLYDRIESIGYKLVIDDEAKR
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHH
FVAEKGYDVQFGARPLKRAIQTHLEDGLSELIITSSLKEKDVIQVSLNKEKGELEMKVIA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA