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The map label for this gene is cirA [H]

Identifier: 29345906

GI number: 29345906

Start: 613244

End: 615391

Strand: Reverse

Name: cirA [H]

Synonym: BT_0496

Alternate gene names: 29345906

Gene position: 615391-613244 (Counterclockwise)

Preceding gene: 29345907

Following gene: 29345905

Centisome position: 9.83

GC content: 43.81

Gene sequence:

>2148_bases
ATGAAACCTACATTTATAGCATCAATCTTGATATTCTCCTTTATAGTAACCTGTTCCACATTCGCACAACAATCAACCGA
GCACATCAGCGGACGTGTTACTGATACCAATGGTGAACCCCTACCAGGTGCGACCATTTCCATAAAAGGAGAAGAAACAG
GAGCCGTCACCAGTGTTGACGGAACCTATACATTACAACTGCCGGGAATCGGTTCATATATCATTACTGCATCTTACATA
GGTTATCAAACCGAACAAAAAAGAATAACCACCGAGAAAGGAAAGAAAGTTAACTTCAGCTTATCCGAAGATCAGTTCGA
CCTCGGAACAGTCGTTGTAACCGGTACCCGTACTCCCAAATTGCTGAAGGACGCTCCCATCATCACCCGGGTTATCACCT
CAGACGATATTAAGAAAGTTAATGCCAACAACGTTGCCGACCTGCTGAAAACAGAGTTGCCCGGTATCGAATTTTCCTTC
TCTATGGATCAGCAAACCGCTATTAATATGCAAGGCTTCGGCGGTAATTCCGTACTGTTTCTGGTAGATGGCGAACGGCT
GGCAGGGGAAACACTGAATAATGTAGACTACGAACGTCTGAATCTCGACAATGTAGAACGCATAGAGATAGTGAAAGGTG
CTGCATCTACCCTTTACGGTTCCAGTGCTATCGGAGGAGTAATTAACATCATCACCCGCGAATCGGACGATCCATGGAAC
TTAAATCTTAATTCACGTTTCTCCGAACACAACGACCAGCGGTGTGGTGGCACTGCAGGATTTAATGCAGGTAAATTCAA
CAGCCTGACCAACGTGCAGTATAATAATGTAGACACTTATGCCGTAGACAATCCGGGAGATTTCTCTACAGTGTTCGGAA
GCCGGGTGTGGAACTTCAAAGAACGTTTAATATACCGTCCGCTGGAAACGCTCAAACTGACGGGAAGAGTCGGCTATTAT
TTCCGTGAACGCAATAAACCGGGGGATACCCAGGACAGATACCGTGGATTCAGCGGTGGAATGAAAGCTAACTACACCTT
CAATATAATGAGTAACCTTGAAGTCGGTTATACTTTCGACCAGTATGATAAGAGTGATTATCAGTCTCTTTATAAAAATG
ACGTGCGTGATTACAGTAATGTACAGCACAATGTGCATGCACTCTATAATTATACCTTCAACGGAAAGCATACGCTGACT
GTCGGCGCCGACTACCTGCGCGATTATCTGATGTCTTACCAATTCACTGATAACGCAGACCACACCATGCATACGGCAGA
TGCGTTCGGTCAGTTCGACTGGAACCCCACAGAAAGACTGAATGTGATAGCCGGATTACGGTTCGACTACTTCTCCGACT
CCAATGTACGCCATCTGTCTCCACATTTGGGAATGATGTATAAGATAGGCAATTGTTCATTAAGAGGATCGTATTCGCAA
GGATTCCGCTCTCCTACCCTGAAGGAGATGTATATGGTGTTCAATATGGCAAATATGATGATGATTTATGGTAATCCGGA
CCTTAAGTCGGAAACAAGCCATAATTTCTCTGTATCTGCCGAATATACCAAGAGTCGTTATAACTTCTCTATTACAGGAT
ATTATAACCTGGTACACAATCGTATCAATACCGTTTACAGCGAAGACCCCAAAGGACAAATCTATACCAATACCGACAAA
ATGGATATTGCAGGAATTGACGCCAACGTTTCCGCCAAGTATCCTTGCGGACTCGGCTATCGTCTGTCATACACATATAT
TCATGAGTTCATGCGCGACGGTCAAAAGAAATTCACGGATACACGTCCCCATACGGCAACTGTAAGAATCGACTGGGGCA
AGACTCTGAACAAAATAGATTTCAACTACTCACTCAACGGACGTTTGCTGTCAAAAGTTAAAACAAACATCTACAACGAT
AGTTTCAACAACCCGTCTGCCGGAAGCCAGGCAGTCGAATACCCGGGATATATGATATGGGATCTTACTTTCTCGTTGGG
AATTATAAAAGGGATCAATATGAATCTGGCTGTAAACAACCTGTTCGACTATGTGCCGGATTATTATTATTTCAACTCTC
CTACCACGACGGGAACCAACCTGACATTAGGACTATCACTGGATATAGACAGGCTCTTCAAAAAATAA

Upstream 100 bases:

>100_bases
CCAACTATACCAATGCCAGAGGCATAAAAGGCTATATCGACTTCGATTTCCTATATCCACTTGATTTCGAAGAAAACAAC
TAAGAAACCAATTACAAAGA

Downstream 100 bases:

>100_bases
ACGGCAACAATAGAACTACATACAAAGCTAAAAATAAGAGAAATGAAAAAGAAAAGTAAAATCATTTTAGGTGGATGCAT
CGTTGTAGCAGCCCTGATAG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MKPTFIASILIFSFIVTCSTFAQQSTEHISGRVTDTNGEPLPGATISIKGEETGAVTSVDGTYTLQLPGIGSYIITASYI
GYQTEQKRITTEKGKKVNFSLSEDQFDLGTVVVTGTRTPKLLKDAPIITRVITSDDIKKVNANNVADLLKTELPGIEFSF
SMDQQTAINMQGFGGNSVLFLVDGERLAGETLNNVDYERLNLDNVERIEIVKGAASTLYGSSAIGGVINIITRESDDPWN
LNLNSRFSEHNDQRCGGTAGFNAGKFNSLTNVQYNNVDTYAVDNPGDFSTVFGSRVWNFKERLIYRPLETLKLTGRVGYY
FRERNKPGDTQDRYRGFSGGMKANYTFNIMSNLEVGYTFDQYDKSDYQSLYKNDVRDYSNVQHNVHALYNYTFNGKHTLT
VGADYLRDYLMSYQFTDNADHTMHTADAFGQFDWNPTERLNVIAGLRFDYFSDSNVRHLSPHLGMMYKIGNCSLRGSYSQ
GFRSPTLKEMYMVFNMANMMMIYGNPDLKSETSHNFSVSAEYTKSRYNFSITGYYNLVHNRINTVYSEDPKGQIYTNTDK
MDIAGIDANVSAKYPCGLGYRLSYTYIHEFMRDGQKKFTDTRPHTATVRIDWGKTLNKIDFNYSLNGRLLSKVKTNIYND
SFNNPSAGSQAVEYPGYMIWDLTFSLGIIKGINMNLAVNNLFDYVPDYYYFNSPTTTGTNLTLGLSLDIDRLFKK

Sequences:

>Translated_715_residues
MKPTFIASILIFSFIVTCSTFAQQSTEHISGRVTDTNGEPLPGATISIKGEETGAVTSVDGTYTLQLPGIGSYIITASYI
GYQTEQKRITTEKGKKVNFSLSEDQFDLGTVVVTGTRTPKLLKDAPIITRVITSDDIKKVNANNVADLLKTELPGIEFSF
SMDQQTAINMQGFGGNSVLFLVDGERLAGETLNNVDYERLNLDNVERIEIVKGAASTLYGSSAIGGVINIITRESDDPWN
LNLNSRFSEHNDQRCGGTAGFNAGKFNSLTNVQYNNVDTYAVDNPGDFSTVFGSRVWNFKERLIYRPLETLKLTGRVGYY
FRERNKPGDTQDRYRGFSGGMKANYTFNIMSNLEVGYTFDQYDKSDYQSLYKNDVRDYSNVQHNVHALYNYTFNGKHTLT
VGADYLRDYLMSYQFTDNADHTMHTADAFGQFDWNPTERLNVIAGLRFDYFSDSNVRHLSPHLGMMYKIGNCSLRGSYSQ
GFRSPTLKEMYMVFNMANMMMIYGNPDLKSETSHNFSVSAEYTKSRYNFSITGYYNLVHNRINTVYSEDPKGQIYTNTDK
MDIAGIDANVSAKYPCGLGYRLSYTYIHEFMRDGQKKFTDTRPHTATVRIDWGKTLNKIDFNYSLNGRLLSKVKTNIYND
SFNNPSAGSQAVEYPGYMIWDLTFSLGIIKGINMNLAVNNLFDYVPDYYYFNSPTTTGTNLTLGLSLDIDRLFKK
>Mature_715_residues
MKPTFIASILIFSFIVTCSTFAQQSTEHISGRVTDTNGEPLPGATISIKGEETGAVTSVDGTYTLQLPGIGSYIITASYI
GYQTEQKRITTEKGKKVNFSLSEDQFDLGTVVVTGTRTPKLLKDAPIITRVITSDDIKKVNANNVADLLKTELPGIEFSF
SMDQQTAINMQGFGGNSVLFLVDGERLAGETLNNVDYERLNLDNVERIEIVKGAASTLYGSSAIGGVINIITRESDDPWN
LNLNSRFSEHNDQRCGGTAGFNAGKFNSLTNVQYNNVDTYAVDNPGDFSTVFGSRVWNFKERLIYRPLETLKLTGRVGYY
FRERNKPGDTQDRYRGFSGGMKANYTFNIMSNLEVGYTFDQYDKSDYQSLYKNDVRDYSNVQHNVHALYNYTFNGKHTLT
VGADYLRDYLMSYQFTDNADHTMHTADAFGQFDWNPTERLNVIAGLRFDYFSDSNVRHLSPHLGMMYKIGNCSLRGSYSQ
GFRSPTLKEMYMVFNMANMMMIYGNPDLKSETSHNFSVSAEYTKSRYNFSITGYYNLVHNRINTVYSEDPKGQIYTNTDK
MDIAGIDANVSAKYPCGLGYRLSYTYIHEFMRDGQKKFTDTRPHTATVRIDWGKTLNKIDFNYSLNGRLLSKVKTNIYND
SFNNPSAGSQAVEYPGYMIWDLTFSLGIIKGINMNLAVNNLFDYVPDYYYFNSPTTTGTNLTLGLSLDIDRLFKK

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=636, Percent_Identity=24.8427672955975, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790405, Length=659, Percent_Identity=25.948406676783, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1786798, Length=674, Percent_Identity=22.2551928783383, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80685; Mature: 80685

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTFIASILIFSFIVTCSTFAQQSTEHISGRVTDTNGEPLPGATISIKGEETGAVTSVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEECCCCCCEEECC
GTYTLQLPGIGSYIITASYIGYQTEQKRITTEKGKKVNFSLSEDQFDLGTVVVTGTRTPK
CEEEEEECCCCCEEEEEEECCCCCHHHHEECCCCCEEEEEECCCCCCEEEEEEECCCCCH
LLKDAPIITRVITSDDIKKVNANNVADLLKTELPGIEFSFSMDQQTAINMQGFGGNSVLF
HHHCCCEEEEEECCCCCEECCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCEEEE
LVDGERLAGETLNNVDYERLNLDNVERIEIVKGAASTLYGSSAIGGVINIITRESDDPWN
EECCCHHCCCHHCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHCCEEEEEECCCCCCEE
LNLNSRFSEHNDQRCGGTAGFNAGKFNSLTNVQYNNVDTYAVDNPGDFSTVFGSRVWNFK
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHH
ERLIYRPLETLKLTGRVGYYFRERNKPGDTQDRYRGFSGGMKANYTFNIMSNLEVGYTFD
HHHHHCCHHHEEEECCEEEEEEECCCCCCCHHHHCCCCCCCCCEEEEEEEECCEECEEEC
QYDKSDYQSLYKNDVRDYSNVQHNVHALYNYTFNGKHTLTVGADYLRDYLMSYQFTDNAD
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEECHHHHHHHHHHEEECCCCC
HTMHTADAFGQFDWNPTERLNVIAGLRFDYFSDSNVRHLSPHLGMMYKIGNCSLRGSYSQ
CEEEEHHHCCCCCCCHHHHEEEEEEEEEEECCCCCCEECCCCCCEEEEECCEEEECCHHH
GFRSPTLKEMYMVFNMANMMMIYGNPDLKSETSHNFSVSAEYTKSRYNFSITGYYNLVHN
CCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECCEEEEEEEEEHHHHHH
RINTVYSEDPKGQIYTNTDKMDIAGIDANVSAKYPCGLGYRLSYTYIHEFMRDGQKKFTD
HHHHHCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHCCHHHCCC
TRPHTATVRIDWGKTLNKIDFNYSLNGRLLSKVKTNIYNDSFNNPSAGSQAVEYPGYMIW
CCCCEEEEEEECCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEE
DLTFSLGIIKGINMNLAVNNLFDYVPDYYYFNSPTTTGTNLTLGLSLDIDRLFKK
EEEEHHHHHCCCCCEEEHHHHHHHCCCCEEECCCCCCCCEEEEEEEECHHHHHCC
>Mature Secondary Structure
MKPTFIASILIFSFIVTCSTFAQQSTEHISGRVTDTNGEPLPGATISIKGEETGAVTSVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEECCCCCCEEECC
GTYTLQLPGIGSYIITASYIGYQTEQKRITTEKGKKVNFSLSEDQFDLGTVVVTGTRTPK
CEEEEEECCCCCEEEEEEECCCCCHHHHEECCCCCEEEEEECCCCCCEEEEEEECCCCCH
LLKDAPIITRVITSDDIKKVNANNVADLLKTELPGIEFSFSMDQQTAINMQGFGGNSVLF
HHHCCCEEEEEECCCCCEECCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCEEEE
LVDGERLAGETLNNVDYERLNLDNVERIEIVKGAASTLYGSSAIGGVINIITRESDDPWN
EECCCHHCCCHHCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHCCEEEEEECCCCCCEE
LNLNSRFSEHNDQRCGGTAGFNAGKFNSLTNVQYNNVDTYAVDNPGDFSTVFGSRVWNFK
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHH
ERLIYRPLETLKLTGRVGYYFRERNKPGDTQDRYRGFSGGMKANYTFNIMSNLEVGYTFD
HHHHHCCHHHEEEECCEEEEEEECCCCCCCHHHHCCCCCCCCCEEEEEEEECCEECEEEC
QYDKSDYQSLYKNDVRDYSNVQHNVHALYNYTFNGKHTLTVGADYLRDYLMSYQFTDNAD
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEECHHHHHHHHHHEEECCCCC
HTMHTADAFGQFDWNPTERLNVIAGLRFDYFSDSNVRHLSPHLGMMYKIGNCSLRGSYSQ
CEEEEHHHCCCCCCCHHHHEEEEEEEEEEECCCCCCEECCCCCCEEEEECCEEEECCHHH
GFRSPTLKEMYMVFNMANMMMIYGNPDLKSETSHNFSVSAEYTKSRYNFSITGYYNLVHN
CCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECCEEEEEEEEEHHHHHH
RINTVYSEDPKGQIYTNTDKMDIAGIDANVSAKYPCGLGYRLSYTYIHEFMRDGQKKFTD
HHHHHCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHCCHHHCCC
TRPHTATVRIDWGKTLNKIDFNYSLNGRLLSKVKTNIYNDSFNNPSAGSQAVEYPGYMIW
CCCCEEEEEEECCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEE
DLTFSLGIIKGINMNLAVNNLFDYVPDYYYFNSPTTTGTNLTLGLSLDIDRLFKK
EEEEHHHHHCCCCCEEEHHHHHHHCCCCEEECCCCCCCCEEEEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]