Click here to switch to the map view.

The map label for this gene is serB [H]

Identifier: 29144847

GI number: 29144847

Start: 4767942

End: 4768910

Strand: Direct

Name: serB [H]

Synonym: t4617

Alternate gene names: 29144847

Gene position: 4767942-4768910 (Clockwise)

Preceding gene: 29144844

Following gene: 29144848

Centisome position: 99.5

GC content: 57.38

Gene sequence:

>969_bases
ATGCCTAACATTACCTGGTGCGATCTGCCTGAAGATGTCTCTTTATGGCCTGGTTTGCCTCTTTCTTTAAGCGGCGACGA
GGTGATGCCTCTGGATTACCATGCAGGCCGCAGCGGTTGGCTGCTGTATGGGCGCGGGCTGGATAAGCAGCGTTTAACTC
AATATCAGACCAAACTGGGCGCGGCAATGGTGATTGTCGCCGCCTGGTGCGTGGAGGATTATCAGGTCATTCGTCTGGCG
GGGTCGCTGACGCCGCGTGCGACGCGGCTGGCGCATGAGGCGCAGCTGGATGTCGCGCCGCTGGGTAAAATTCCGCATTT
GCGCACGCCGGGGCTGCTGGTCATGGATATGGATTCCACGGCGATCCAGATTGAGTGTATCGATGAAATCGCTAAGCTGG
CCGGTACCGGTGAGAAGGTGGCTGAAGTGACGGAGCGCGCGATGCGCGGCGAGCTTGATTTTACCGCCAGCCTGCGCAGC
CGCGTGGCGACGCTGAAAGGCGCGGATGCCGATATTTTGCGCCAGGTGCGCGGGAATCTGCCGCTAATGCCAGGATTAAC
GCAGTTGGTGCTAAAACTGGAAGCGCTCGGCTGGAAAATCGCTATCGCCTCCGGCGGCTTCACTTTCTTCGCCGACTATC
TGCGTGACCAGCTACGCCTGACGGCGGCGGTCGCCAATGAGCTGGAGATCATGGACGGTAAATTTACCGGTCACGTTATC
GGCGATATTGTGGATGCTGAGTATAAAGCCAATACCTTGCTTCGTCTGGCGCAAGAGCATGACATCCCGCTGGCGCAGAC
GGTGGCGATTGGCGACGGCGCTAACGATCTGCCAATGATCAAAGCGGCAGGGTTAGGTATTGCCTTCCATGCCAAGCCAA
AAGTAAACGAAAAGACGGAGATTACGATCCGCCACGCTGACCTGATGGGCGTGTTTTGCATTCTCTCCGGCAGCATGAAC
CAGAAATGA

Upstream 100 bases:

>100_bases
ATTTGAGGCTTAATGTTGCCAGAAGCGATGGTTACAAGGTAGCCTCATGCGTTATTTTCCGCGGGGCGGTTACCGGCCTG
AACGATTTACAGGAGCTTTA

Downstream 100 bases:

>100_bases
TTAATCTGCCCAATGGCAAGGCGACCGTAGGCCGGATAAGCGCCAGCGCCATCCGGCAACAGCGTTAACGAAAGAGGTAA
AACGTGGCAAAAGCTCCCAA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQTKLGAAMVIVAAWCVEDYQVIRLA
GSLTPRATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEKVAEVTERAMRGELDFTASLRS
RVATLKGADADILRQVRGNLPLMPGLTQLVLKLEALGWKIAIASGGFTFFADYLRDQLRLTAAVANELEIMDGKFTGHVI
GDIVDAEYKANTLLRLAQEHDIPLAQTVAIGDGANDLPMIKAAGLGIAFHAKPKVNEKTEITIRHADLMGVFCILSGSMN
QK

Sequences:

>Translated_322_residues
MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQTKLGAAMVIVAAWCVEDYQVIRLA
GSLTPRATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEKVAEVTERAMRGELDFTASLRS
RVATLKGADADILRQVRGNLPLMPGLTQLVLKLEALGWKIAIASGGFTFFADYLRDQLRLTAAVANELEIMDGKFTGHVI
GDIVDAEYKANTLLRLAQEHDIPLAQTVAIGDGANDLPMIKAAGLGIAFHAKPKVNEKTEITIRHADLMGVFCILSGSMN
QK
>Mature_321_residues
PNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQTKLGAAMVIVAAWCVEDYQVIRLAG
SLTPRATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEKVAEVTERAMRGELDFTASLRSR
VATLKGADADILRQVRGNLPLMPGLTQLVLKLEALGWKIAIASGGFTFFADYLRDQLRLTAAVANELEIMDGKFTGHVIG
DIVDAEYKANTLLRLAQEHDIPLAQTVAIGDGANDLPMIKAAGLGIAFHAKPKVNEKTEITIRHADLMGVFCILSGSMNQ
K

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=181, Percent_Identity=29.8342541436464, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1790849, Length=322, Percent_Identity=93.4782608695652, Blast_Score=622, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI115534454, Length=240, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=247, Percent_Identity=38.4615384615385, Blast_Score=161, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35007; Mature: 34876

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQTKLG
CCCCEECCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHH
AAMVIVAAWCVEDYQVIRLAGSLTPRATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDST
HHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCC
AIQIECIDEIAKLAGTGEKVAEVTERAMRGELDFTASLRSRVATLKGADADILRQVRGNL
EEEEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCC
PLMPGLTQLVLKLEALGWKIAIASGGFTFFADYLRDQLRLTAAVANELEIMDGKFTGHVI
CCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
GDIVDAEYKANTLLRLAQEHDIPLAQTVAIGDGANDLPMIKAAGLGIAFHAKPKVNEKTE
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCEEEEECCCCCCCCEE
ITIRHADLMGVFCILSGSMNQK
EEEEEHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQTKLG
CCCEECCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHH
AAMVIVAAWCVEDYQVIRLAGSLTPRATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDST
HHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCC
AIQIECIDEIAKLAGTGEKVAEVTERAMRGELDFTASLRSRVATLKGADADILRQVRGNL
EEEEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCC
PLMPGLTQLVLKLEALGWKIAIASGGFTFFADYLRDQLRLTAAVANELEIMDGKFTGHVI
CCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
GDIVDAEYKANTLLRLAQEHDIPLAQTVAIGDGANDLPMIKAAGLGIAFHAKPKVNEKTE
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCEEEEECCCCCCCCEE
ITIRHADLMGVFCILSGSMNQK
EEEEEHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]