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The map label for this gene is yidY [H]

Identifier: 29143970

GI number: 29143970

Start: 3784695

End: 3785882

Strand: Reverse

Name: yidY [H]

Synonym: t3676

Alternate gene names: 29143970

Gene position: 3785882-3784695 (Counterclockwise)

Preceding gene: 29143971

Following gene: 161486774

Centisome position: 79.0

GC content: 55.39

Gene sequence:

>1188_bases
ATGAAACGTTTTCTACTGTGTAGTTTTGCCCTGGTTTTACTCTATCCTGCTGGTATTGATATGTATCTGGTCGGTTTACC
GCGTATAGCCGCCGATCTGAACGCCAGCGAGGCGCAGTTGCATATCGCCTTCTCCGTTTACCTGGCCGGAATGGCGACGG
CCATGCTGTTTGCCGGGAAGATAGCCGACCAGTCAGGCCGCAAGCCGGTCGCGATCGTCGGCGCGATCGTCTTTATGATG
GCCTCACTGCTTTGTTCACGGGCGTCGGAAGGCTCGCTATTTCTGAGTGGGCGTTTTCTTCAGGGGGTAGGAGCAGGCGG
CTGCTATGTGGTGGCGTTCGCCATTCTGCGCGACACGCTCGACGAGCATCGCCGGGCGAAAGTGCTGTCATTATTGAATG
GGATTACCTGTATTGTGCCGGTACTCGCCCCGGTGATGGGGCATTTGATTATGCTTCGTTTCCCCTGGCAAAGTCTGTTC
TATACGATGTCCACGATGGGCATTATGGTGGGCCTGTTATCACTGTTTATCCTGCGCGAGACGCGCCCGGCAAGGCTGGC
TCCACGCGATTTATCACCATCGTCGTCCGCCGCCGAGTCGCTGGTTAACCGTTTTTTCGTTAGTCGACTAGCGATCACCA
CCCTTAGCGTGTCGGTGATCCTGACCTTCGTCAATGCCTCTCCAGTGCTGCTGATGGAGGTGATGGGATTTAGCCGTGGC
GACTATGCCATTACCATGGCGCTCACCGCAGGCGTCAGCATGGTCGTCTCTTTTTCTACCCCTTTTGCGCTTGGGTTATT
TAAGCCGCGAACCTTAATGCTCGTCTCACAGGGGCTGTTTTTGACGGCTGGCGTGACGTTAAGCCTTGCTCATACCAATA
CCGTCACGCTCTTTGGCCTGACGCTTATCTGCGCCGGATTCTCGGTTGGTTTTGGCGTCGCGATGAGCCAGGCGCTGGGG
CCGTTTTCGCTGCGCGCCGGAGTGGCCAGTTCCACGCTGGGTATCGCTCAGGTTTGCGGTTCATCACTGTGGATTTGGCT
GGCGGCAATACTCGGTATCAGCGCGATGAATATGCTGATCGGGATTCTGATTGGTTGTAGCATAGTGAGTATTCTGCTGA
TCTTCTCCGTCGCGCCCAACAGGTCCGTAGCCGAGCATGAAGAAATCCCTTACCAGTCTCGATCTTAA

Upstream 100 bases:

>100_bases
GCAATGATTTCCCATGCGGAAATCACTGTTGTCCAAATGACAACTCGTCTCGCGCAACGTCGCCCCGTATTCTTAGCGCC
ACACTTTTCGTGAGGCCGCT

Downstream 100 bases:

>100_bases
TCTGCTGTTATGCCTACAGTTACTCATGCAGGAGCGCAGCGTCACTAAAGCTGCAAAACGGATGAACGTAACGCCCTCTG
CGGTCAGCAAATCGCTGGCG

Product: multidrug efflux system protein MdtL

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGKIADQSGRKPVAIVGAIVFMM
ASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVMGHLIMLRFPWQSLF
YTMSTMGIMVGLLSLFILRETRPARLAPRDLSPSSSAAESLVNRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALG
PFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVAPNRSVAEHEEIPYQSRS

Sequences:

>Translated_395_residues
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGKIADQSGRKPVAIVGAIVFMM
ASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVMGHLIMLRFPWQSLF
YTMSTMGIMVGLLSLFILRETRPARLAPRDLSPSSSAAESLVNRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALG
PFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVAPNRSVAEHEEIPYQSRS
>Mature_395_residues
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGKIADQSGRKPVAIVGAIVFMM
ASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVMGHLIMLRFPWQSLF
YTMSTMGIMVGLLSLFILRETRPARLAPRDLSPSSSAAESLVNRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALG
PFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVAPNRSVAEHEEIPYQSRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790146, Length=393, Percent_Identity=78.3715012722646, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1788509, Length=241, Percent_Identity=26.9709543568465, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI48994889, Length=237, Percent_Identity=28.2700421940928, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790794, Length=246, Percent_Identity=26.0162601626016, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082312, Length=342, Percent_Identity=27.4853801169591, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787065, Length=237, Percent_Identity=24.0506329113924, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41957; Mature: 41957

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGK
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHH
IADQSGRKPVAIVGAIVFMMASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTL
HCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHH
DEHRRAKVLSLLNGITCIVPVLAPVMGHLIMLRFPWQSLFYTMSTMGIMVGLLSLFILRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
TRPARLAPRDLSPSSSAAESLVNRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGL
CEEEEHHHHHCHHHEEEECCCCEECCCCCCEEEHHHCCCEEEECCEEEEECCCHHHHHHH
TLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLI
HHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GILIGCSIVSILLIFSVAPNRSVAEHEEIPYQSRS
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGK
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHH
IADQSGRKPVAIVGAIVFMMASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTL
HCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHH
DEHRRAKVLSLLNGITCIVPVLAPVMGHLIMLRFPWQSLFYTMSTMGIMVGLLSLFILRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
TRPARLAPRDLSPSSSAAESLVNRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGL
CEEEEHHHHHCHHHEEEECCCCEECCCCCCEEEHHHCCCEEEECCEEEEECCCHHHHHHH
TLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLI
HHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GILIGCSIVSILLIFSVAPNRSVAEHEEIPYQSRS
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA