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The map label for this gene is fixA [H]

Identifier: 29140618

GI number: 29140618

Start: 88492

End: 89262

Strand: Direct

Name: fixA [H]

Synonym: t0076

Alternate gene names: 29140618

Gene position: 88492-89262 (Clockwise)

Preceding gene: 29140611

Following gene: 29140619

Centisome position: 1.85

GC content: 52.01

Gene sequence:

>771_bases
ATGAAGATAATTACTTGCTACAAATGCGTACCTGATGAGCAGGATATTGCGATTAATAATGCTGACGGAACACTCGATTT
CAGCAAAGCGGATAGCAAAATCAGCCAATATGATCTGAATGCAATTGAAGCTGCTTGCCAGTTAAAACAGCAGTTGGGAG
ACGCTCAGGTTGTCGCCATGAGCGTTGGCGGCAAAGCGCTGACTAATGCAAAAGGGCGCAAAGATGTCCTCTCTCGTGGC
CCTGATGAACTGATTGTGGTCATTGACGATCAATTTGAGCAGGCGCTGCCGCAACACACCGCTACCGCGCTGGCCGCCGC
GGCGCAAAAATCAGGTTTCGATCTACTTATCTGCGGCGACGGTTCTTCCGATCTTTATGCTCAGCAGGTTGGTTTGCTGG
TGGGCGAAGCGCTGAACATTCCGGCGATTAACGGCGTGAGTAAAATCCTCTCTCTTACCGACAGCACATTGACGGTAGAA
CGCGAACTGGAAGATGAAGTTGAAACGCTGAGCATCCCGCTCCCGGCGGTGATCGCGGTTTCCACCGACATTAACACCCC
ACAAATCCCTTCGATGAAAGCCATTCTTGGCGCGGCGAAAAAACCGGTTCAGGTCTGGTCGCCTGCGGATATCGGGCTGA
ACAGCGTACCCGCGTATTCCACACAACAGGTTGCCGCACCGAAGCAGCGCGAGCGTCAGCGTGTGGTGATTGAAGGTGAC
GGTGAAGAACAAATCGCCGCGTTTGTCGAGAATCTGCGCAAAATCATTTAA

Upstream 100 bases:

>100_bases
ATATTGGTGATTAAGGTTTTATTTCCGAATTAAAGAGCGTGATATCTGTATTTAACACCGCCGATATAAATACGTTTCCT
TCATGATTTCTGGAGATGCA

Downstream 100 bases:

>100_bases
TTATCAGGGGATGTTATGAACAAATTTTCCAGTGTCTGGGTATTCAGCGATACCCCTTCTCGTCTGCCCGAACTGATGAG
TGGTGCGCAGGCTGTAGGTG

Product: electron transfer flavoprotein FixA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSTQQVAAPKQRERQRVVIEGD
GEEQIAAFVENLRKII

Sequences:

>Translated_256_residues
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSTQQVAAPKQRERQRVVIEGD
GEEQIAAFVENLRKII
>Mature_256_residues
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSTQQVAAPKQRERQRVVIEGD
GEEQIAAFVENLRKII

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI62420877, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081682, Length=256, Percent_Identity=87.890625, Blast_Score=440, Evalue=1e-125,
Organism=Escherichia coli, GI2367123, Length=255, Percent_Identity=55.6862745098039, Blast_Score=264, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI25141345, Length=200, Percent_Identity=25, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 27252; Mature: 27252

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS01065 ETF_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAM
CCEEEEEECCCCCCCEEEECCCCCEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
SVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGD
ECCCCHHCCCCCHHHHHHCCCCEEEEEECCHHHHHCHHHHHHHHHHHHHCCCCEEEEECC
GSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVERELEDEVETLSIPLPAVIAV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEE
STDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSTQQVAAPKQRERQRVVIEGD
ECCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCHHHCCCEEEEECC
GEEQIAAFVENLRKII
CHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAM
CCEEEEEECCCCCCCEEEECCCCCEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
SVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGD
ECCCCHHCCCCCHHHHHHCCCCEEEEEECCHHHHHCHHHHHHHHHHHHHCCCCEEEEECC
GSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVERELEDEVETLSIPLPAVIAV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEE
STDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSTQQVAAPKQRERQRVVIEGD
ECCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCHHHCCCEEEEECC
GEEQIAAFVENLRKII
CHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA