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The map label for this gene is bcfA [H]

Identifier: 29140565

GI number: 29140565

Start: 24473

End: 25015

Strand: Direct

Name: bcfA [H]

Synonym: t0022

Alternate gene names: 29140565

Gene position: 24473-25015 (Clockwise)

Preceding gene: 29140564

Following gene: 29140566

Centisome position: 0.51

GC content: 52.12

Gene sequence:

>543_bases
ATGAAAAAGCCTGTACTAGCATTAATGGTCTCTGCCATTGCCTTTGGCGGAATGTTGTCCACCGCGCAAGCGGATACTAC
AACCGTCACTGGCGGTACGGTAAATTTTGTCGGACAGGTCGTTGACGCCGCCTGTTCTGTTTCCGCTGACTCTGTCGATC
AGACCGTGACATTAGGCCAGGTTCGCGCCAGTAAATTAACCGAGGCCGGTATGGCGGCGAATCAAAAAGAAGATTTCACC
ATTAAACTGGAAGACTGCGATACTCAGACCAGCCAGAATGCGGCGGTGATTTTTAATGGCCAGCAGGACGCAAACCAGCC
GGGTTCGCTGGCGAATACCGCTGGGGCAGGTTCGGCGACGAATGTGGCACTACAACTTTATGGACCGGATGGCCAGGCGC
TGAATATTGGTGAATCGTCCAGTACTGTTACCTTGAACGATGGCGAAAACGTTATTCCGCTTAGCGTGGATTATATCGCT
ACCGGTACGGCGACTGCCGGTAATGTTACCGCGACGGCGACATTTAGCATGGTTTATTCCTGA

Upstream 100 bases:

>100_bases
TTCGCATAAGAAAAGTCGTGATATTGCTGTGAAGAAATATCAGCAGCCGTTTCGTTAAAAAATCTGATTACCCTCATTTT
TATATTTAAAAGGAGCTTGA

Downstream 100 bases:

>100_bases
TTCCTTATCGGGATTTTTTTCTCGTCTGTTGGGAGGCGAGAAAGGGGCGTTACGCGCGTCACTGCGCGTAACAAACCGAC
GGCATCAGGATATTACGCAG

Product: fimbrial subunit

Products: NA

Alternate protein names: Type-1C pilin [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKKPVLALMVSAIAFGGMLSTAQADTTTVTGGTVNFVGQVVDAACSVSADSVDQTVTLGQVRASKLTEAGMAANQKEDFT
IKLEDCDTQTSQNAAVIFNGQQDANQPGSLANTAGAGSATNVALQLYGPDGQALNIGESSSTVTLNDGENVIPLSVDYIA
TGTATAGNVTATATFSMVYS

Sequences:

>Translated_180_residues
MKKPVLALMVSAIAFGGMLSTAQADTTTVTGGTVNFVGQVVDAACSVSADSVDQTVTLGQVRASKLTEAGMAANQKEDFT
IKLEDCDTQTSQNAAVIFNGQQDANQPGSLANTAGAGSATNVALQLYGPDGQALNIGESSSTVTLNDGENVIPLSVDYIA
TGTATAGNVTATATFSMVYS
>Mature_180_residues
MKKPVLALMVSAIAFGGMLSTAQADTTTVTGGTVNFVGQVVDAACSVSADSVDQTVTLGQVRASKLTEAGMAANQKEDFT
IKLEDCDTQTSQNAAVIFNGQQDANQPGSLANTAGAGSATNVALQLYGPDGQALNIGESSSTVTLNDGENVIPLSVDYIA
TGTATAGNVTATATFSMVYS

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI87081804, Length=180, Percent_Identity=40, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790769, Length=155, Percent_Identity=49.0322580645161, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87081753, Length=161, Percent_Identity=40.9937888198758, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI87082421, Length=187, Percent_Identity=28.8770053475936, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 18165; Mature: 18165

Theoretical pI: Translated: 3.78; Mature: 3.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPVLALMVSAIAFGGMLSTAQADTTTVTGGTVNFVGQVVDAACSVSADSVDQTVTLGQ
CCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEHH
VRASKLTEAGMAANQKEDFTIKLEDCDTQTSQNAAVIFNGQQDANQPGSLANTAGAGSAT
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
NVALQLYGPDGQALNIGESSSTVTLNDGENVIPLSVDYIATGTATAGNVTATATFSMVYS
EEEEEEECCCCCEEEECCCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure
MKKPVLALMVSAIAFGGMLSTAQADTTTVTGGTVNFVGQVVDAACSVSADSVDQTVTLGQ
CCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEHH
VRASKLTEAGMAANQKEDFTIKLEDCDTQTSQNAAVIFNGQQDANQPGSLANTAGAGSAT
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
NVALQLYGPDGQALNIGESSSTVTLNDGENVIPLSVDYIATGTATAGNVTATATFSMVYS
EEEEEEECCCCCEEEECCCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]