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The map label for this gene is aspC [H]

Identifier: 28572874

GI number: 28572874

Start: 827185

End: 828399

Strand: Direct

Name: aspC [H]

Synonym: TW733

Alternate gene names: 28572874

Gene position: 827185-828399 (Clockwise)

Preceding gene: 28572864

Following gene: 28572880

Centisome position: 89.33

GC content: 44.36

Gene sequence:

>1215_bases
ATGTCAGAGCGCATATCGAAAAGGTGTTCCAAACTGGGCGAGTCTGTAACTCTTTCAATAGACTCAAAAGCCAAACGAAT
GAAGAAGGCAGGAAAGCCGATAATAAGCTATGCTGCTGGAGAGCCCGATTTTCCAACACCTGAACACATTGTCAGTCGCT
GTCAGCTTGCCGCTGCCACAAGAAGTAATCATGTCTATACAGAAACTGCAGGACTGGCTGAACTGCGCGAAGCAATTGCA
GAAAAAACCCTAGCCGATTCATTCCTAAAAGTGTCAGAATCACAGATTCTCATTACGAACGGATGCAAACAAGCGGTCTA
TATGGCATGCCAAACTATTCTGGATCCGAATGATGAAGTCATTCTACCCACACCGTACTGGACAACATATCCAGAAAGTA
TTCGCGCAGCTGGGGCAAAGGTTGTAATTCCTGCAACTGATAGTTTTTACGTAACAGTTGATCAGTTACAGTCGGTGCTT
ACCAACAAAACAAAAGCAATTATCTTGTCTTCGCCATCTAACCCCAGTGGTGCTGTTTATTCCTTGGACTCACTAAGAGA
CATTGCACGATTTGCCAAAAAACACGGTATATGGATTATTTCTGATGAGATTTATCAAAATATCTATTATTCGGGAAGGG
TGGCACCGGGATTTGGAGAGGCTCTTCCCGAGATAAAGGATCAACTTATTCTGGTCAACGGGTTGTCCAAAACCTATGCA
ATGACTGGGTGGCGCATTGGGTGGATGATTGGACCACAGGACATAATAAATGCCTCTGTGAAATTACAATCACACATTTG
CTCACATGTTTCCAATATAATGCAGCAAGCCGCCCTGGAGGCTCTGACCGGACCACAGGACTGTGTTGCCTATATGAGAG
ATGAATTCAAAAAACGCAGGGACCTTATGCTTCGCGAGCTGGGGAGAATAAAGGGTCTATCCATCCCAAAACCTGATGGT
GCATTTTATATATATCCTGATGTATCAGCGTTCATTGGAAGAAGAATTGCTGGCAGAATGATTCATTCATCTTTTGAGCT
TGCTGAACTAGTTCTTAGTGAGACTCTGGTTGCGACTGTTCCTGGTGAAGCCTTTGGAACAAAAGGGCACCTTAGGCTTT
CATACGCCCTAGATGAAACAAGTTTGCTGGAGGGAACAGGACGGCTTGTGGAATTCTTTGATACAGCGAACTCCGACATG
ACGAAGGTATTTTGA

Upstream 100 bases:

>100_bases
GCTGCTCTACCAATTGAGCCACCGCCCTAAAAACCGAAGCAAAAAACATACTCGAGTATAGGATAATAGGCCAACAAAAT
AAAGTTTGTAGAATGCTACC

Downstream 100 bases:

>100_bases
GTCTACAGTTCGAGACCAACAAAAACCGGCTCAGGAATGAGGTGTATATCGAATTTTCTTGAGACGGTTCGTGTAATAAG
TCCTGCAAGTTCAATCACTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSERISKRCSKLGESVTLSIDSKAKRMKKAGKPIISYAAGEPDFPTPEHIVSRCQLAAATRSNHVYTETAGLAELREAIA
EKTLADSFLKVSESQILITNGCKQAVYMACQTILDPNDEVILPTPYWTTYPESIRAAGAKVVIPATDSFYVTVDQLQSVL
TNKTKAIILSSPSNPSGAVYSLDSLRDIARFAKKHGIWIISDEIYQNIYYSGRVAPGFGEALPEIKDQLILVNGLSKTYA
MTGWRIGWMIGPQDIINASVKLQSHICSHVSNIMQQAALEALTGPQDCVAYMRDEFKKRRDLMLRELGRIKGLSIPKPDG
AFYIYPDVSAFIGRRIAGRMIHSSFELAELVLSETLVATVPGEAFGTKGHLRLSYALDETSLLEGTGRLVEFFDTANSDM
TKVF

Sequences:

>Translated_404_residues
MSERISKRCSKLGESVTLSIDSKAKRMKKAGKPIISYAAGEPDFPTPEHIVSRCQLAAATRSNHVYTETAGLAELREAIA
EKTLADSFLKVSESQILITNGCKQAVYMACQTILDPNDEVILPTPYWTTYPESIRAAGAKVVIPATDSFYVTVDQLQSVL
TNKTKAIILSSPSNPSGAVYSLDSLRDIARFAKKHGIWIISDEIYQNIYYSGRVAPGFGEALPEIKDQLILVNGLSKTYA
MTGWRIGWMIGPQDIINASVKLQSHICSHVSNIMQQAALEALTGPQDCVAYMRDEFKKRRDLMLRELGRIKGLSIPKPDG
AFYIYPDVSAFIGRRIAGRMIHSSFELAELVLSETLVATVPGEAFGTKGHLRLSYALDETSLLEGTGRLVEFFDTANSDM
TKVF
>Mature_403_residues
SERISKRCSKLGESVTLSIDSKAKRMKKAGKPIISYAAGEPDFPTPEHIVSRCQLAAATRSNHVYTETAGLAELREAIAE
KTLADSFLKVSESQILITNGCKQAVYMACQTILDPNDEVILPTPYWTTYPESIRAAGAKVVIPATDSFYVTVDQLQSVLT
NKTKAIILSSPSNPSGAVYSLDSLRDIARFAKKHGIWIISDEIYQNIYYSGRVAPGFGEALPEIKDQLILVNGLSKTYAM
TGWRIGWMIGPQDIINASVKLQSHICSHVSNIMQQAALEALTGPQDCVAYMRDEFKKRRDLMLRELGRIKGLSIPKPDGA
FYIYPDVSAFIGRRIAGRMIHSSFELAELVLSETLVATVPGEAFGTKGHLRLSYALDETSLLEGTGRLVEFFDTANSDMT
KVF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=329, Percent_Identity=29.7872340425532, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI56713256, Length=329, Percent_Identity=29.7872340425532, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI95147551, Length=325, Percent_Identity=26.7692307692308, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI169881279, Length=325, Percent_Identity=26.7692307692308, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4507369, Length=421, Percent_Identity=23.9904988123515, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169881281, Length=232, Percent_Identity=25.4310344827586, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI149944424, Length=329, Percent_Identity=22.7963525835866, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1788722, Length=360, Percent_Identity=28.8888888888889, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1786816, Length=391, Percent_Identity=26.0869565217391, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788627, Length=357, Percent_Identity=27.7310924369748, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790797, Length=271, Percent_Identity=26.5682656826568, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=25.2631578947368, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=398, Percent_Identity=24.1206030150754, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=398, Percent_Identity=24.1206030150754, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=275, Percent_Identity=25.8181818181818, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71981209, Length=354, Percent_Identity=22.0338983050847, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=22.6221079691517, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=356, Percent_Identity=25, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573069, Length=325, Percent_Identity=26.7692307692308, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646114, Length=325, Percent_Identity=26.7692307692308, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573067, Length=325, Percent_Identity=26.7692307692308, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573065, Length=325, Percent_Identity=26.7692307692308, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859735, Length=342, Percent_Identity=25.7309941520468, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24641770, Length=405, Percent_Identity=23.9506172839506, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641760, Length=405, Percent_Identity=23.9506172839506, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641768, Length=405, Percent_Identity=23.9506172839506, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641766, Length=405, Percent_Identity=23.9506172839506, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641764, Length=405, Percent_Identity=23.9506172839506, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45551451, Length=405, Percent_Identity=23.9506172839506, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44472; Mature: 44340

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERISKRCSKLGESVTLSIDSKAKRMKKAGKPIISYAAGEPDFPTPEHIVSRCQLAAAT
CCHHHHHHHHHCCCEEEEEECHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
RSNHVYTETAGLAELREAIAEKTLADSFLKVSESQILITNGCKQAVYMACQTILDPNDEV
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCE
ILPTPYWTTYPESIRAAGAKVVIPATDSFYVTVDQLQSVLTNKTKAIILSSPSNPSGAVY
EECCCCCCCCCHHHHHCCCEEEEECCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCEE
SLDSLRDIARFAKKHGIWIISDEIYQNIYYSGRVAPGFGEALPEIKDQLILVNGLSKTYA
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEECCCHHHE
MTGWRIGWMIGPQDIINASVKLQSHICSHVSNIMQQAALEALTGPQDCVAYMRDEFKKRR
ECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DLMLRELGRIKGLSIPKPDGAFYIYPDVSAFIGRRIAGRMIHSSFELAELVLSETLVATV
HHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
PGEAFGTKGHLRLSYALDETSLLEGTGRLVEFFDTANSDMTKVF
CCHHCCCCCCEEEEEECCCHHHHHCCCHHHHHHHCCCCCHHHCC
>Mature Secondary Structure 
SERISKRCSKLGESVTLSIDSKAKRMKKAGKPIISYAAGEPDFPTPEHIVSRCQLAAAT
CHHHHHHHHHCCCEEEEEECHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
RSNHVYTETAGLAELREAIAEKTLADSFLKVSESQILITNGCKQAVYMACQTILDPNDEV
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCE
ILPTPYWTTYPESIRAAGAKVVIPATDSFYVTVDQLQSVLTNKTKAIILSSPSNPSGAVY
EECCCCCCCCCHHHHHCCCEEEEECCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCEE
SLDSLRDIARFAKKHGIWIISDEIYQNIYYSGRVAPGFGEALPEIKDQLILVNGLSKTYA
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEECCCHHHE
MTGWRIGWMIGPQDIINASVKLQSHICSHVSNIMQQAALEALTGPQDCVAYMRDEFKKRR
ECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DLMLRELGRIKGLSIPKPDGAFYIYPDVSAFIGRRIAGRMIHSSFELAELVLSETLVATV
HHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
PGEAFGTKGHLRLSYALDETSLLEGTGRLVEFFDTANSDMTKVF
CCHHCCCCCCEEEEEECCCHHHHHCCCHHHHHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8675024 [H]