| Definition | Tropheryma whipplei TW08/27, complete genome. |
|---|---|
| Accession | NC_004551 |
| Length | 925,938 |
Click here to switch to the map view.
The map label for this gene is murC [H]
Identifier: 28572689
GI number: 28572689
Start: 575696
End: 577123
Strand: Reverse
Name: murC [H]
Synonym: TW541
Alternate gene names: 28572689
Gene position: 577123-575696 (Counterclockwise)
Preceding gene: 28572690
Following gene: 28572688
Centisome position: 62.33
GC content: 43.28
Gene sequence:
>1428_bases ATGGGGATTTATGCGAAGGACGTACCCCTTCCCGAATCAATAAATAGAGCTCACTTTTGTGGTATTGGCGGTTCTGGTAT GTCCGCAGTTGCAAGGCTCTTTCTGCAGCTTGGTATTTCTGTATCTGGTACTGATAGAAGTGATTCGATAACACTTTCTG AACTTTCCCAGGCGGGTGCAATTGTAAAAGTTGGACATGATCCAGCAATGCTTGAGGGTGTTGATACATTTGTTTATTCG GGGGCTATAGATAGCTCTAATCCGGAGTACGCGTACGCAGAACGTGCCCGCATTAATCTGTTACACAGATCTCTTGCCCT TAAGTGGATCACCCGAGGAAAAAGACTTATAAGCATTGCGGGATCTCACGGAAAAACATCGACAACTGCCATGATTGCAA CTGCCCTCCATGTACTGGGCAATAAATGCGGTGTTGCAAACGGGTCATACATGAATTTTTTTTCAGCAAATGCACTTTTG GGATTAAATGACTTGTTTGTCATCGAGGCTGATGAGTCTGATGGCTCTTTTCTTTTCTACGACACGGATATATCAGTTGT GAACAATATAAGTATGGATCATGTGGATTATTACGGCTCGCAATCTGCTTTGGAAGGCAGTTTTTTTGACTTTTCATTAC GTTCGTCCGATGCAGCGGTTATTTCGCTTGATGATGCGGCATGTATAAAGATCGCAAGCAAACTATTGCAGTCTTCTGGT TCTAGAGGACCCTCAAAGAGGGTAATAACTTTTGGTAAGAATAGGTCGGCGGATGTTTGTCTTTATGAGATGGGCTGCAT GAATCCAGCAAGATTTACGGTTTCATATGAGGGCCGCTTTTATAATGCAGGTTTCAAAGGTCTTTTTGGGGAGCACCACG CGGTAAATACCTGTGCCGCGCTGTCAGTTCTATTGTGTCTCGGATACGGAATCTCTGAGTCGCTTGAGGCAATTCTATCT TTTAGCGGAACCAGAAGAAGGCTTGAGTTGCACTTTGATTCAGGCGGGAAAGATGGAATAAAAATTTTCGATGATTACGC TCACCACCCGAGGGAGATAAGAACAGCTCTAACTGCAATTCGCAGCGTGCAGCATACGCGGCTTATAGCTCTTTTTCAAC CCCATTTATATTCGAGAACCGCGGCATTACACAGGGAGTTTGCATCTGTTTTGGAAAATTGTGCTGATTTTACAATTATC CTGCCGGTTTACGCAGCACGTGAGTCACCAATTCCTGGAGTAGATGCGAAGATTATTTTTGATGCATATAGAGATAAACG CAATGTCGTGATGCTTGAAGGATTTGATCACACATTGAGTTTTTTTAGGCAATTCTTGCGCGATGGTGATTTAGTTATCA CACTTGGTTGTGGAGATGTTTATAAGATAATTCCAAGTATTGTCGAACAGCTTAGATCCGCAAGATGA
Upstream 100 bases:
>100_bases AACGGCGTGAGGCAATGTCCATTGCGGCAAAACGGTTTGCTATCTGTAATGCTGCCCAAAATACTGCGAGCCTGATTGAG CTCGCACTTTCCTCTTAGGC
Downstream 100 bases:
>100_bases GTGCGAATTCGGTGACGGTTTAGATAATGACAGTTGTAGATAATGCCTATCAGAACTTTCTTTATTGCCGCAAGCAGCGC AAAGATTACGAGAGGGTCTG
Product: UDP-N-acetylmuramate--alanine ligase
Products: NA
Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]
Number of amino acids: Translated: 475; Mature: 474
Protein sequence:
>475_residues MGIYAKDVPLPESINRAHFCGIGGSGMSAVARLFLQLGISVSGTDRSDSITLSELSQAGAIVKVGHDPAMLEGVDTFVYS GAIDSSNPEYAYAERARINLLHRSLALKWITRGKRLISIAGSHGKTSTTAMIATALHVLGNKCGVANGSYMNFFSANALL GLNDLFVIEADESDGSFLFYDTDISVVNNISMDHVDYYGSQSALEGSFFDFSLRSSDAAVISLDDAACIKIASKLLQSSG SRGPSKRVITFGKNRSADVCLYEMGCMNPARFTVSYEGRFYNAGFKGLFGEHHAVNTCAALSVLLCLGYGISESLEAILS FSGTRRRLELHFDSGGKDGIKIFDDYAHHPREIRTALTAIRSVQHTRLIALFQPHLYSRTAALHREFASVLENCADFTII LPVYAARESPIPGVDAKIIFDAYRDKRNVVMLEGFDHTLSFFRQFLRDGDLVITLGCGDVYKIIPSIVEQLRSAR
Sequences:
>Translated_475_residues MGIYAKDVPLPESINRAHFCGIGGSGMSAVARLFLQLGISVSGTDRSDSITLSELSQAGAIVKVGHDPAMLEGVDTFVYS GAIDSSNPEYAYAERARINLLHRSLALKWITRGKRLISIAGSHGKTSTTAMIATALHVLGNKCGVANGSYMNFFSANALL GLNDLFVIEADESDGSFLFYDTDISVVNNISMDHVDYYGSQSALEGSFFDFSLRSSDAAVISLDDAACIKIASKLLQSSG SRGPSKRVITFGKNRSADVCLYEMGCMNPARFTVSYEGRFYNAGFKGLFGEHHAVNTCAALSVLLCLGYGISESLEAILS FSGTRRRLELHFDSGGKDGIKIFDDYAHHPREIRTALTAIRSVQHTRLIALFQPHLYSRTAALHREFASVLENCADFTII LPVYAARESPIPGVDAKIIFDAYRDKRNVVMLEGFDHTLSFFRQFLRDGDLVITLGCGDVYKIIPSIVEQLRSAR >Mature_474_residues GIYAKDVPLPESINRAHFCGIGGSGMSAVARLFLQLGISVSGTDRSDSITLSELSQAGAIVKVGHDPAMLEGVDTFVYSG AIDSSNPEYAYAERARINLLHRSLALKWITRGKRLISIAGSHGKTSTTAMIATALHVLGNKCGVANGSYMNFFSANALLG LNDLFVIEADESDGSFLFYDTDISVVNNISMDHVDYYGSQSALEGSFFDFSLRSSDAAVISLDDAACIKIASKLLQSSGS RGPSKRVITFGKNRSADVCLYEMGCMNPARFTVSYEGRFYNAGFKGLFGEHHAVNTCAALSVLLCLGYGISESLEAILSF SGTRRRLELHFDSGGKDGIKIFDDYAHHPREIRTALTAIRSVQHTRLIALFQPHLYSRTAALHREFASVLENCADFTIIL PVYAARESPIPGVDAKIIFDAYRDKRNVVMLEGFDHTLSFFRQFLRDGDLVITLGCGDVYKIIPSIVEQLRSAR
Specific function: Cell wall formation [H]
COG id: COG0773
COG function: function code M; UDP-N-acetylmuramate-alanine ligase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786279, Length=475, Percent_Identity=31.7894736842105, Blast_Score=171, Evalue=1e-43, Organism=Escherichia coli, GI1790680, Length=372, Percent_Identity=28.2258064516129, Blast_Score=120, Evalue=1e-28,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR016040 - InterPro: IPR005758 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.8 [H]
Molecular weight: Translated: 51802; Mature: 51670
Theoretical pI: Translated: 6.91; Mature: 6.91
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGIYAKDVPLPESINRAHFCGIGGSGMSAVARLFLQLGISVSGTDRSDSITLSELSQAGA CCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCEEHHHHHHCCC IVKVGHDPAMLEGVDTFVYSGAIDSSNPEYAYAERARINLLHRSLALKWITRGKRLISIA EEEECCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE GSHGKTSTTAMIATALHVLGNKCGVANGSYMNFFSANALLGLNDLFVIEADESDGSFLFY CCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCEEEE DTDISVVNNISMDHVDYYGSQSALEGSFFDFSLRSSDAAVISLDDAACIKIASKLLQSSG ECCCHHHHCCCHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCC SRGPSKRVITFGKNRSADVCLYEMGCMNPARFTVSYEGRFYNAGFKGLFGEHHAVNTCAA CCCCCCCEEEECCCCCCCEEEEECCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHH LSVLLCLGYGISESLEAILSFSGTRRRLELHFDSGGKDGIKIFDDYAHHPREIRTALTAI HHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEHHHCCCHHHHHHHHHHH RSVQHTRLIALFQPHLYSRTAALHREFASVLENCADFTIILPVYAARESPIPGVDAKIIF HHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCEEEE DAYRDKRNVVMLEGFDHTLSFFRQFLRDGDLVITLGCGDVYKIIPSIVEQLRSAR EECCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCC >Mature Secondary Structure GIYAKDVPLPESINRAHFCGIGGSGMSAVARLFLQLGISVSGTDRSDSITLSELSQAGA CCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCEEHHHHHHCCC IVKVGHDPAMLEGVDTFVYSGAIDSSNPEYAYAERARINLLHRSLALKWITRGKRLISIA EEEECCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE GSHGKTSTTAMIATALHVLGNKCGVANGSYMNFFSANALLGLNDLFVIEADESDGSFLFY CCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCEEEE DTDISVVNNISMDHVDYYGSQSALEGSFFDFSLRSSDAAVISLDDAACIKIASKLLQSSG ECCCHHHHCCCHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCC SRGPSKRVITFGKNRSADVCLYEMGCMNPARFTVSYEGRFYNAGFKGLFGEHHAVNTCAA CCCCCCCEEEECCCCCCCEEEEECCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHH LSVLLCLGYGISESLEAILSFSGTRRRLELHFDSGGKDGIKIFDDYAHHPREIRTALTAI HHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEHHHCCCHHHHHHHHHHH RSVQHTRLIALFQPHLYSRTAALHREFASVLENCADFTIILPVYAARESPIPGVDAKIIF HHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCEEEE DAYRDKRNVVMLEGFDHTLSFFRQFLRDGDLVITLGCGDVYKIIPSIVEQLRSAR EECCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA