Click here to switch to the map view.

The map label for this gene is 28572656

Identifier: 28572656

GI number: 28572656

Start: 544909

End: 545445

Strand: Reverse

Name: 28572656

Synonym: TW507

Alternate gene names: NA

Gene position: 545445-544909 (Counterclockwise)

Preceding gene: 28572657

Following gene: 28572655

Centisome position: 58.91

GC content: 45.62

Gene sequence:

>537_bases
ATGCAGGAAGGTTCATCTGATTTTGCCGGTATTCCGGATGGATATAAGAGACTTTGGACCCCACATCGTGTTGTGTACCT
GGAAGGTGCCAGGCATGATGGAAATCCCGAGACCTGTCCATTTTGCTCTGCATACAGAAAAACAGATGAGGAGGGTCTTA
TAGTCTATCGAGGGGACTTGTCTTATGTTGTTATGAATCTTTATCCATACAATTCGGGACATACCCTTGTGTGCCCATAT
CGGCATATTGCAACCTATGATCTTGCGAGTTCTGATGAGATTCTTGAAATGGGTCTTTTGCTGCAGAAAGCTATACTGGT
TAGCAAGCGCGTGTTGGGCTGTGAAGGCTTTAATATCGGTATAAATCAAGGCCGCGTTGCGGGTGCTGGGATTGCTGGGC
ATTTGCATCAGCACATTGTTCCGCGTTGGGCTTTTGATTCTAATTTTTTTCCGATTATTGCGAGGACAAAAGCCTTGCCG
AAACTGATAGAACAAGTGAGATGTGACCTACAGCGTGGGTGGGACGATTTAGTTTGA

Upstream 100 bases:

>100_bases
CCATTCAGAAATGCTTTGATGGAATTTGTGCAAGTATAGACCGTAAAAAACAGATTCAGACGCGTATAGATTTCGATTCT
GTTCTTGAATAGTTGATTAT

Downstream 100 bases:

>100_bases
CGGGGGCGTGATATGGGGCTTGACAATTTAAAGGTAGGTCTTGCGCAAATGCTCAAAGGGGGCGTAATAATGGATGTTGT
TACACCCGATCAGGCAAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MQEGSSDFAGIPDGYKRLWTPHRVVYLEGARHDGNPETCPFCSAYRKTDEEGLIVYRGDLSYVVMNLYPYNSGHTLVCPY
RHIATYDLASSDEILEMGLLLQKAILVSKRVLGCEGFNIGINQGRVAGAGIAGHLHQHIVPRWAFDSNFFPIIARTKALP
KLIEQVRCDLQRGWDDLV

Sequences:

>Translated_178_residues
MQEGSSDFAGIPDGYKRLWTPHRVVYLEGARHDGNPETCPFCSAYRKTDEEGLIVYRGDLSYVVMNLYPYNSGHTLVCPY
RHIATYDLASSDEILEMGLLLQKAILVSKRVLGCEGFNIGINQGRVAGAGIAGHLHQHIVPRWAFDSNFFPIIARTKALP
KLIEQVRCDLQRGWDDLV
>Mature_178_residues
MQEGSSDFAGIPDGYKRLWTPHRVVYLEGARHDGNPETCPFCSAYRKTDEEGLIVYRGDLSYVVMNLYPYNSGHTLVCPY
RHIATYDLASSDEILEMGLLLQKAILVSKRVLGCEGFNIGINQGRVAGAGIAGHLHQHIVPRWAFDSNFFPIIARTKALP
KLIEQVRCDLQRGWDDLV

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 19994; Mature: 19994

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEGSSDFAGIPDGYKRLWTPHRVVYLEGARHDGNPETCPFCSAYRKTDEEGLIVYRGDL
CCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEECCC
SYVVMNLYPYNSGHTLVCPYRHIATYDLASSDEILEMGLLLQKAILVSKRVLGCEGFNIG
EEEEEEEEECCCCCEEECCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
INQGRVAGAGIAGHLHQHIVPRWAFDSNFFPIIARTKALPKLIEQVRCDLQRGWDDLV
CCCCCEECCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MQEGSSDFAGIPDGYKRLWTPHRVVYLEGARHDGNPETCPFCSAYRKTDEEGLIVYRGDL
CCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEECCC
SYVVMNLYPYNSGHTLVCPYRHIATYDLASSDEILEMGLLLQKAILVSKRVLGCEGFNIG
EEEEEEEEECCCCCEEECCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
INQGRVAGAGIAGHLHQHIVPRWAFDSNFFPIIARTKALPKLIEQVRCDLQRGWDDLV
CCCCCEECCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]