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The map label for this gene is pdxS

Identifier: 28572655

GI number: 28572655

Start: 544033

End: 544896

Strand: Reverse

Name: pdxS

Synonym: TW506

Alternate gene names: 28572655

Gene position: 544896-544033 (Counterclockwise)

Preceding gene: 28572656

Following gene: 28572654

Centisome position: 58.85

GC content: 48.84

Gene sequence:

>864_bases
ATGGGGCTTGACAATTTAAAGGTAGGTCTTGCGCAAATGCTCAAAGGGGGCGTAATAATGGATGTTGTTACACCCGATCA
GGCAAAGATAGCCGAGGATGCTGGCGCTGTTGCTGTTATGGCATTGGAAAAAATACCGTCTGATATTCGTGCTTCTGGTG
GCGTGTCGCGTATGAGCGATCCCGGTTTGATTGAGCGGGTAATGGATTCAGTGTCAATTCCTGTTATGGCGAAAGTAAGG
ATCGGTCATTTTGCCGAAGCGCAAATCCTTCAGTCACTAAAAGTTGATTACATAGATGAATCGGAAGTTTTGTCTGTTGC
GGATTCTTCGTATCATATCGACAAACGAAAATTTACAGTTCCTTTTGTTTGTGGTGCGACCAATCTCGGCGAAGCCTTAC
GTCGTATTTCGGAAGGCGCTTCTATGATCAGGTCAAAAGGGGAGGCTGGTACGGGCGATATTGCGCAGGCTACAAAACAT
ATACGTGCTATCCTGTCTGAGATATCTGCGTTGACACAAGCGCGGGAAGATGAACTTCCTGCCAGGGCCAGGGAGCTCGG
CGCGCCAATTGATCTTGTGCGAGAGACAGCCAGGCTTGGCAGATTGCCGGTTGTTTTGTTTACTGCCGGCGGCATTGCAA
CACCAGCGGATTCTTCGCTTGTTATGCAGCTTGGATCTGACGGGGTATTTGTTGGTTCGGGAATTTTTAAATCTGAAGAT
CCAAAAGCCTATGCCGCAGCAATTGTTCAGGCGACTGCTCAATACGATGATGCGGATCTCCTGGCCCGCGTGTCGCGTAA
TTTAGGTCAGGCTATGCCCGGTGTTTCCAATCTTGATGTGCGTTTTTCGAGTCGGGGTGTGTAA

Upstream 100 bases:

>100_bases
TCCGATTATTGCGAGGACAAAAGCCTTGCCGAAACTGATAGAACAAGTGAGATGTGACCTACAGCGTGGGTGGGACGATT
TAGTTTGACGGGGGCGTGAT

Downstream 100 bases:

>100_bases
TGACCGTTGGAGTTCTCTCCCTCCAGGGAAGTTTTTATGAGCACCTATCTATTTTGAGCAGGCTAAACACTGACCACATT
CAAGTAAAAACTTCTGAAGA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGLDNLKVGLAQMLKGGVIMDVVTPDQAKIAEDAGAVAVMALEKIPSDIRASGGVSRMSDPGLIERVMDSVSIPVMAKVR
IGHFAEAQILQSLKVDYIDESEVLSVADSSYHIDKRKFTVPFVCGATNLGEALRRISEGASMIRSKGEAGTGDIAQATKH
IRAILSEISALTQAREDELPARARELGAPIDLVRETARLGRLPVVLFTAGGIATPADSSLVMQLGSDGVFVGSGIFKSED
PKAYAAAIVQATAQYDDADLLARVSRNLGQAMPGVSNLDVRFSSRGV

Sequences:

>Translated_287_residues
MGLDNLKVGLAQMLKGGVIMDVVTPDQAKIAEDAGAVAVMALEKIPSDIRASGGVSRMSDPGLIERVMDSVSIPVMAKVR
IGHFAEAQILQSLKVDYIDESEVLSVADSSYHIDKRKFTVPFVCGATNLGEALRRISEGASMIRSKGEAGTGDIAQATKH
IRAILSEISALTQAREDELPARARELGAPIDLVRETARLGRLPVVLFTAGGIATPADSSLVMQLGSDGVFVGSGIFKSED
PKAYAAAIVQATAQYDDADLLARVSRNLGQAMPGVSNLDVRFSSRGV
>Mature_286_residues
GLDNLKVGLAQMLKGGVIMDVVTPDQAKIAEDAGAVAVMALEKIPSDIRASGGVSRMSDPGLIERVMDSVSIPVMAKVRI
GHFAEAQILQSLKVDYIDESEVLSVADSSYHIDKRKFTVPFVCGATNLGEALRRISEGASMIRSKGEAGTGDIAQATKHI
RAILSEISALTQAREDELPARARELGAPIDLVRETARLGRLPVVLFTAGGIATPADSSLVMQLGSDGVFVGSGIFKSEDP
KAYAAAIVQATAQYDDADLLARVSRNLGQAMPGVSNLDVRFSSRGV

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=284, Percent_Identity=62.6760563380282, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6321049, Length=274, Percent_Identity=63.8686131386861, Blast_Score=357, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6323996, Length=274, Percent_Identity=63.5036496350365, Blast_Score=356, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_TROW8 (Q83HM5)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789435.1
- ProteinModelPortal:   Q83HM5
- SMR:   Q83HM5
- STRING:   Q83HM5
- GeneID:   1064710
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW506
- eggNOG:   COG0214
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- PhylomeDB:   Q83HM5
- ProtClustDB:   PRK04180
- BioCyc:   TWHI218496:TW0480-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 30263; Mature: 30132

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLDNLKVGLAQMLKGGVIMDVVTPDQAKIAEDAGAVAVMALEKIPSDIRASGGVSRMSD
CCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCHHHHHHHHHCCHHHHHCCCCCCCCC
PGLIERVMDSVSIPVMAKVRIGHFAEAQILQSLKVDYIDESEVLSVADSSYHIDKRKFTV
CHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECCCEEEE
PFVCGATNLGEALRRISEGASMIRSKGEAGTGDIAQATKHIRAILSEISALTQAREDELP
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ARARELGAPIDLVRETARLGRLPVVLFTAGGIATPADSSLVMQLGSDGVFVGSGIFKSED
HHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHEECCCCEEEECCCCCCCC
PKAYAAAIVQATAQYDDADLLARVSRNLGQAMPGVSNLDVRFSSRGV
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
>Mature Secondary Structure 
GLDNLKVGLAQMLKGGVIMDVVTPDQAKIAEDAGAVAVMALEKIPSDIRASGGVSRMSD
CCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCHHHHHHHHHCCHHHHHCCCCCCCCC
PGLIERVMDSVSIPVMAKVRIGHFAEAQILQSLKVDYIDESEVLSVADSSYHIDKRKFTV
CHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECCCEEEE
PFVCGATNLGEALRRISEGASMIRSKGEAGTGDIAQATKHIRAILSEISALTQAREDELP
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ARARELGAPIDLVRETARLGRLPVVLFTAGGIATPADSSLVMQLGSDGVFVGSGIFKSED
HHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHEECCCCEEEECCCCCCCC
PKAYAAAIVQATAQYDDADLLARVSRNLGQAMPGVSNLDVRFSSRGV
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174