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The map label for this gene is era

Identifier: 28572637

GI number: 28572637

Start: 526847

End: 527752

Strand: Reverse

Name: era

Synonym: TW488

Alternate gene names: 28572637

Gene position: 527752-526847 (Counterclockwise)

Preceding gene: 28572638

Following gene: 161501890

Centisome position: 57.0

GC content: 39.62

Gene sequence:

>906_bases
TTGGTCGTATCTAGATCCCCCGGAGGCTATAGATCGGGGATAATTACACTCGTTGGCAGGCCAAATGTTGGAAAGTCGAC
GCTTATAAATTCTCTTGTTGGAGAACATCTTTCGATAACCAGTGATAAGCCACAAACTACAAGAAGAATTATCCGCGGTG
TTATAAGCAGGATGAATGCACAAATTGCAATAACAGATACACCGGGGATTCATAAACCGAAAACCCCATTCGGTAAAGGT
TTGAATGAAATGACCACTTGTGCTCTGTCTGCCTCCGACTCAATTGGTATATGCCTCCCGGTAAATCAAAAAATAGGCTC
GGGGGACAGGTTCATCCTGGATAAAGTTGAGGCCATTGGGCCATATAAAAAAATTGCAATTGTAACAAAAATTGACCGCG
TAGAAAAGCGTGATTTGTTGCTAAAGTTATCCGAAATATCTGACCTTGGGTGTAATTTTGCCGCCGTTGTTCCAGTTTCT
GCAAAACGGGCGGTTCAGATTGATTTATTGAAAGATGTCTTTTTCGAGAATTGCCTCAATTTTTCTGAAAAGCTATTTTT
TGATCATGAAAAGCCTTCCGTGTCTGATCAGATATCTGAGCTAATTCGTGAAAAAGCACTTTGTCTATTGGAGCAAGAGA
TTCCCCACTCATTGCTTGTAGAGGTTGAAGAGATTTTGACGGATAGCAATAGGGTTTTTATTCATGCCAATTTGTATGTT
GAAAGAAACAGTCAAAAAATGATTGTTTTAGGCAAGGGTGGCAGAACAATTAAAAACATATCAATTACTTCGCGGTTAGC
CATTGAATCATTTCTTGGCAAAAAGGTATATCTACGTCTTATTGTGAAGGTTGTGAAGAACTGGCAAAAAAGTGAGTCAT
TTCTTGGCAAGATTTACCTTTCCTGA

Upstream 100 bases:

>100_bases
TTTTCTCTCCAGGCAAAGCTCATAGAGGATTTTTTTGCCCTGGAGAATCTTGGAACGCCTTCTGAAGAGATTACAATAAC
CCCAGACCTTAGGCCTTCGC

Downstream 100 bases:

>100_bases
ATGGTACGTGTGTAAGAATTGGGATGTGAGCGGGCATTATCGTGACAGAGCTATTGTTCTTAGAACAAAACCACTGGGTG
AAGCAGACAGGATCATTACC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MVVSRSPGGYRSGIITLVGRPNVGKSTLINSLVGEHLSITSDKPQTTRRIIRGVISRMNAQIAITDTPGIHKPKTPFGKG
LNEMTTCALSASDSIGICLPVNQKIGSGDRFILDKVEAIGPYKKIAIVTKIDRVEKRDLLLKLSEISDLGCNFAAVVPVS
AKRAVQIDLLKDVFFENCLNFSEKLFFDHEKPSVSDQISELIREKALCLLEQEIPHSLLVEVEEILTDSNRVFIHANLYV
ERNSQKMIVLGKGGRTIKNISITSRLAIESFLGKKVYLRLIVKVVKNWQKSESFLGKIYLS

Sequences:

>Translated_301_residues
MVVSRSPGGYRSGIITLVGRPNVGKSTLINSLVGEHLSITSDKPQTTRRIIRGVISRMNAQIAITDTPGIHKPKTPFGKG
LNEMTTCALSASDSIGICLPVNQKIGSGDRFILDKVEAIGPYKKIAIVTKIDRVEKRDLLLKLSEISDLGCNFAAVVPVS
AKRAVQIDLLKDVFFENCLNFSEKLFFDHEKPSVSDQISELIREKALCLLEQEIPHSLLVEVEEILTDSNRVFIHANLYV
ERNSQKMIVLGKGGRTIKNISITSRLAIESFLGKKVYLRLIVKVVKNWQKSESFLGKIYLS
>Mature_301_residues
MVVSRSPGGYRSGIITLVGRPNVGKSTLINSLVGEHLSITSDKPQTTRRIIRGVISRMNAQIAITDTPGIHKPKTPFGKG
LNEMTTCALSASDSIGICLPVNQKIGSGDRFILDKVEAIGPYKKIAIVTKIDRVEKRDLLLKLSEISDLGCNFAAVVPVS
AKRAVQIDLLKDVFFENCLNFSEKLFFDHEKPSVSDQISELIREKALCLLEQEIPHSLLVEVEEILTDSNRVFIHANLYV
ERNSQKMIVLGKGGRTIKNISITSRLAIESFLGKKVYLRLIVKVVKNWQKSESFLGKIYLS

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=35.0340136054422, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_TROW8 (Q83NI3)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789417.1
- HSSP:   Q9X1F8
- ProteinModelPortal:   Q83NI3
- SMR:   Q83NI3
- STRING:   Q83NI3
- GeneID:   1064692
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW488
- eggNOG:   COG1159
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- ProtClustDB:   PRK00089
- BioCyc:   TWHI218496:TW0462-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 33390; Mature: 33390

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSRSPGGYRSGIITLVGRPNVGKSTLINSLVGEHLSITSDKPQTTRRIIRGVISRMNA
CEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHCCC
QIAITDTPGIHKPKTPFGKGLNEMTTCALSASDSIGICLPVNQKIGSGDRFILDKVEAIG
EEEEECCCCCCCCCCCHHCCHHHHHEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHC
PYKKIAIVTKIDRVEKRDLLLKLSEISDLGCNFAAVVPVSAKRAVQIDLLKDVFFENCLN
CHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHC
FSEKLFFDHEKPSVSDQISELIREKALCLLEQEIPHSLLVEVEEILTDSNRVFIHANLYV
HHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEEE
ERNSQKMIVLGKGGRTIKNISITSRLAIESFLGKKVYLRLIVKVVKNWQKSESFLGKIYL
EECCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
S
C
>Mature Secondary Structure
MVVSRSPGGYRSGIITLVGRPNVGKSTLINSLVGEHLSITSDKPQTTRRIIRGVISRMNA
CEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHCCC
QIAITDTPGIHKPKTPFGKGLNEMTTCALSASDSIGICLPVNQKIGSGDRFILDKVEAIG
EEEEECCCCCCCCCCCHHCCHHHHHEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHC
PYKKIAIVTKIDRVEKRDLLLKLSEISDLGCNFAAVVPVSAKRAVQIDLLKDVFFENCLN
CHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHC
FSEKLFFDHEKPSVSDQISELIREKALCLLEQEIPHSLLVEVEEILTDSNRVFIHANLYV
HHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEEE
ERNSQKMIVLGKGGRTIKNISITSRLAIESFLGKKVYLRLIVKVVKNWQKSESFLGKIYL
EECCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12606174