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The map label for this gene is whiA

Identifier: 28572623

GI number: 28572623

Start: 507366

End: 508325

Strand: Reverse

Name: whiA

Synonym: TW474

Alternate gene names: 28572623

Gene position: 508325-507366 (Counterclockwise)

Preceding gene: 28572624

Following gene: 28572622

Centisome position: 54.9

GC content: 45.1

Gene sequence:

>960_bases
GTGAATTCCCTGTTGCAAGCCCTTCACCTCTTGAGATGTGATTTACTCTCTCTTCCGATAGGGGATGCTCAAACAAGATC
AGCTGAACTAACGGCACTGTTGCGCTTTGGGGCTGACCTGAACATAATAAAGAGACGTGTCGTTATAGAGGTAAAACTGT
GTGGATCCTTGCTTCTGAACAGAGTTGAAAGTGTTTTGAGGAATATATACGGTATTACCCCAAAGCTTATTCGTTCAACC
CCCCGCAACGATATAGGTGAGAGTTGCTTTCTTCTGAGAATTGATGACCCATCTTTAGCAAGGAAATTAGGGCTTATTGA
TACGTCGCTTGCGCCCGTACGGGGATTGCCAAATCATCTTGCCCTTGCATCTGGTTCTGCACTAAAGGGACTGGTAAGGG
GTGCAATCCTTGCATCTGGAGTGTTCACAGAATCGACACGCAAATTCGCGATGGAAGTTTATGCACCAAGTAATGAAACA
GCTCTTTGCCTACAGGGGTCTATCAATAAGTTGAATGTTATTGCAAAAATAAAGGAAGTGAGGGGCTCTTACAAGGTTGT
TATTCGCGATATCGATAATGTTGCCCCTCTTCTTCGTAATGTTGGAGCGCGAAACAGCGTCGAAAAAATTGAACAATTTA
TTAAATTGCGGCACCCAGAAAATTTAGGTCCACGCTTACCAAATTTTGATGATGCCAATTTGAGGCGTAGTGCAATAGCT
GCGGCTAGCTCTGTTAGAAGGATTGAGCGGGCATTACAGATTCTTAAGGGAGATGCCCCACAACATTTGTTGTATGCTGG
GCAGTTGCGCCTAAACAATACGCATGCGAGCCTTGAGGAACTTGGCAAACTTGCTGAACCGGCTATGACTAAAGATGCTA
TCGCAGGCAGGATTCGTCGGCTTTTATGCCTTGCCGATAAAAGGGCCAAAACCCTGGGGATTCCTGATACATTCTCTTAG

Upstream 100 bases:

>100_bases
TTCCATTGAAGATATATCTGCATTGCCAGGGTTTGGTGTAAAAACCGCCGAGAAAATCAAGGAATGTGCAGAAGCATTCT
CTTTGAAATAAAATGAACCC

Downstream 100 bases:

>100_bases
TATCCCGTTTCAGTAACTAGTCTGAATAGCGCTACAATTGTCCTTAGCGTTTGGTTTTCGTAGCTCTTTGGTAAGTCGAG
GTGTTTGTTGTTGTATACAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNSLLQALHLLRCDLLSLPIGDAQTRSAELTALLRFGADLNIIKRRVVIEVKLCGSLLLNRVESVLRNIYGITPKLIRST
PRNDIGESCFLLRIDDPSLARKLGLIDTSLAPVRGLPNHLALASGSALKGLVRGAILASGVFTESTRKFAMEVYAPSNET
ALCLQGSINKLNVIAKIKEVRGSYKVVIRDIDNVAPLLRNVGARNSVEKIEQFIKLRHPENLGPRLPNFDDANLRRSAIA
AASSVRRIERALQILKGDAPQHLLYAGQLRLNNTHASLEELGKLAEPAMTKDAIAGRIRRLLCLADKRAKTLGIPDTFS

Sequences:

>Translated_319_residues
MNSLLQALHLLRCDLLSLPIGDAQTRSAELTALLRFGADLNIIKRRVVIEVKLCGSLLLNRVESVLRNIYGITPKLIRST
PRNDIGESCFLLRIDDPSLARKLGLIDTSLAPVRGLPNHLALASGSALKGLVRGAILASGVFTESTRKFAMEVYAPSNET
ALCLQGSINKLNVIAKIKEVRGSYKVVIRDIDNVAPLLRNVGARNSVEKIEQFIKLRHPENLGPRLPNFDDANLRRSAIA
AASSVRRIERALQILKGDAPQHLLYAGQLRLNNTHASLEELGKLAEPAMTKDAIAGRIRRLLCLADKRAKTLGIPDTFS
>Mature_319_residues
MNSLLQALHLLRCDLLSLPIGDAQTRSAELTALLRFGADLNIIKRRVVIEVKLCGSLLLNRVESVLRNIYGITPKLIRST
PRNDIGESCFLLRIDDPSLARKLGLIDTSLAPVRGLPNHLALASGSALKGLVRGAILASGVFTESTRKFAMEVYAPSNET
ALCLQGSINKLNVIAKIKEVRGSYKVVIRDIDNVAPLLRNVGARNSVEKIEQFIKLRHPENLGPRLPNFDDANLRRSAIA
AASSVRRIERALQILKGDAPQHLLYAGQLRLNNTHASLEELGKLAEPAMTKDAIAGRIRRLLCLADKRAKTLGIPDTFS

Specific function: May be required for sporulation

COG id: COG1481

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the whiA transcriptional regulatory family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WHIA_TROW8 (Q83HP5)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789403.1
- STRING:   Q83HP5
- GeneID:   1064314
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW474
- eggNOG:   COG1481
- HOGENOM:   HBG322392
- OMA:   VTCPGPE
- ProtClustDB:   CLSK871931
- BioCyc:   TWHI218496:TW0448-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01420
- InterPro:   IPR003802
- InterPro:   IPR023054
- InterPro:   IPR018478

Pfam domain/function: PF02650 HTH_WhiA; PF10298 WhiA_N

EC number: NA

Molecular weight: Translated: 34921; Mature: 34921

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLLQALHLLRCDLLSLPIGDAQTRSAELTALLRFGADLNIIKRRVVIEVKLCGSLLLN
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHEEHHHHHHHHHH
RVESVLRNIYGITPKLIRSTPRNDIGESCFLLRIDDPSLARKLGLIDTSLAPVRGLPNHL
HHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHCCCCCHH
ALASGSALKGLVRGAILASGVFTESTRKFAMEVYAPSNETALCLQGSINKLNVIAKIKEV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEECCCCHHHHHHHHHHH
RGSYKVVIRDIDNVAPLLRNVGARNSVEKIEQFIKLRHPENLGPRLPNFDDANLRRSAIA
CCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
AASSVRRIERALQILKGDAPQHLLYAGQLRLNNTHASLEELGKLAEPAMTKDAIAGRIRR
HHHHHHHHHHHHHHHHCCCCCHHEEECEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LLCLADKRAKTLGIPDTFS
HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNSLLQALHLLRCDLLSLPIGDAQTRSAELTALLRFGADLNIIKRRVVIEVKLCGSLLLN
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHEEHHHHHHHHHH
RVESVLRNIYGITPKLIRSTPRNDIGESCFLLRIDDPSLARKLGLIDTSLAPVRGLPNHL
HHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHCCCCCHH
ALASGSALKGLVRGAILASGVFTESTRKFAMEVYAPSNETALCLQGSINKLNVIAKIKEV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEECCCCHHHHHHHHHHH
RGSYKVVIRDIDNVAPLLRNVGARNSVEKIEQFIKLRHPENLGPRLPNFDDANLRRSAIA
CCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
AASSVRRIERALQILKGDAPQHLLYAGQLRLNNTHASLEELGKLAEPAMTKDAIAGRIRR
HHHHHHHHHHHHHHHHCCCCCHHEEECEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LLCLADKRAKTLGIPDTFS
HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174