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The map label for this gene is sodA [H]

Identifier: 28572622

GI number: 28572622

Start: 506673

End: 507281

Strand: Reverse

Name: sodA [H]

Synonym: TW473

Alternate gene names: 28572622

Gene position: 507281-506673 (Counterclockwise)

Preceding gene: 28572623

Following gene: 28572621

Centisome position: 54.79

GC content: 44.99

Gene sequence:

>609_bases
TTGTTGTTGTATACACTCCCTAATCTGCCTTACGGTTATTCTGCCCTAGAGCCCTATATAAGCGGAAAAATCATGGAGCT
TCATCACTCAAAGCATCACAAGGCTTATGTTGACGGCGCAAATCAAGCTCTGGAGCAGCTTTGTGAAGCACGTGATAAAG
GTGATTTTTCTAGGGTGCCACAATTGCAAAAGAATCTGGCGTTTAATCTTGCCGGGCATAAGAATCATTCTGTTTTTTGG
AGTGTTCTAACCCCCGAGGTTGGTCAGGCACCGGCCGGTCCCTTTCTTGAGGTTATTGAGCGGGATTTTGGCAGCTTCGA
CTCTTTCATGAATCATTTTTCGGCCGCAGCCTTGAGCATACAGGGCTCTGGGTGGGCCGTTCTGTCATGGGAGCCGGTCG
CATCAAGGCTTATTATTCAGCAATTTTATGATCATCAAAATAACGCAGTATCTGCGAGGAATCTCCTCCTCCTCGATATG
TGGGAGCATGCGTATTACTTAGACTATTTAAATGTAAAAGCTGATTACGTAAAGGCTTTTTGGAGTATAGTCAATTGGCA
TGGCGTTACAGATAAGTTTTTGAAAATTGCCGGCAGGTCTGTCGTTTAG

Upstream 100 bases:

>100_bases
TGATACATTCTCTTAGTATCCCGTTTCAGTAACTAGTCTGAATAGCGCTACAATTGTCCTTAGCGTTTGGTTTTCGTAGC
TCTTTGGTAAGTCGAGGTGT

Downstream 100 bases:

>100_bases
ATAATTTTATAAAGGGGTTGTGTGACGGTCAAAATAGCAATTAATGGCTTTGGAAGAATTGGTCGTGGCTTTTTCAGGGC
TTTATCTTCTCCCTCGTGCA

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLLYTLPNLPYGYSALEPYISGKIMELHHSKHHKAYVDGANQALEQLCEARDKGDFSRVPQLQKNLAFNLAGHKNHSVFW
SVLTPEVGQAPAGPFLEVIERDFGSFDSFMNHFSAAALSIQGSGWAVLSWEPVASRLIIQQFYDHQNNAVSARNLLLLDM
WEHAYYLDYLNVKADYVKAFWSIVNWHGVTDKFLKIAGRSVV

Sequences:

>Translated_202_residues
MLLYTLPNLPYGYSALEPYISGKIMELHHSKHHKAYVDGANQALEQLCEARDKGDFSRVPQLQKNLAFNLAGHKNHSVFW
SVLTPEVGQAPAGPFLEVIERDFGSFDSFMNHFSAAALSIQGSGWAVLSWEPVASRLIIQQFYDHQNNAVSARNLLLLDM
WEHAYYLDYLNVKADYVKAFWSIVNWHGVTDKFLKIAGRSVV
>Mature_202_residues
MLLYTLPNLPYGYSALEPYISGKIMELHHSKHHKAYVDGANQALEQLCEARDKGDFSRVPQLQKNLAFNLAGHKNHSVFW
SVLTPEVGQAPAGPFLEVIERDFGSFDSFMNHFSAAALSIQGSGWAVLSWEPVASRLIIQQFYDHQNNAVSARNLLLLDM
WEHAYYLDYLNVKADYVKAFWSIVNWHGVTDKFLKIAGRSVV

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=193, Percent_Identity=47.1502590673575, Blast_Score=186, Evalue=9e-48,
Organism=Homo sapiens, GI67782305, Length=193, Percent_Identity=47.1502590673575, Blast_Score=186, Evalue=9e-48,
Organism=Homo sapiens, GI67782309, Length=193, Percent_Identity=37.8238341968912, Blast_Score=133, Evalue=9e-32,
Organism=Escherichia coli, GI1790342, Length=204, Percent_Identity=41.6666666666667, Blast_Score=145, Evalue=1e-36,
Organism=Escherichia coli, GI1787946, Length=198, Percent_Identity=33.8383838383838, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17506561, Length=194, Percent_Identity=43.8144329896907, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17569479, Length=190, Percent_Identity=43.1578947368421, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321796, Length=200, Percent_Identity=38.5, Blast_Score=149, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17136812, Length=192, Percent_Identity=41.1458333333333, Blast_Score=158, Evalue=3e-39,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 22900; Mature: 22900

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLYTLPNLPYGYSALEPYISGKIMELHHSKHHKAYVDGANQALEQLCEARDKGDFSRVP
CEEEECCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHH
QLQKNLAFNLAGHKNHSVFWSVLTPEVGQAPAGPFLEVIERDFGSFDSFMNHFSAAALSI
HHHHHHEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHEEE
QGSGWAVLSWEPVASRLIIQQFYDHQNNAVSARNLLLLDMWEHAYYLDYLNVKADYVKAF
CCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHEEEEEHHHHHHHHHHHCCHHHHHHHH
WSIVNWHGVTDKFLKIAGRSVV
HHHHHCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MLLYTLPNLPYGYSALEPYISGKIMELHHSKHHKAYVDGANQALEQLCEARDKGDFSRVP
CEEEECCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHH
QLQKNLAFNLAGHKNHSVFWSVLTPEVGQAPAGPFLEVIERDFGSFDSFMNHFSAAALSI
HHHHHHEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHEEE
QGSGWAVLSWEPVASRLIIQQFYDHQNNAVSARNLLLLDMWEHAYYLDYLNVKADYVKAF
CCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHEEEEEHHHHHHHHHHHCCHHHHHHHH
WSIVNWHGVTDKFLKIAGRSVV
HHHHHCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8307013; 10231372 [H]