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The map label for this gene is mrp [H]

Identifier: 28572395

GI number: 28572395

Start: 259491

End: 260606

Strand: Reverse

Name: mrp [H]

Synonym: TW235

Alternate gene names: 28572395

Gene position: 260606-259491 (Counterclockwise)

Preceding gene: 28572396

Following gene: 28572357

Centisome position: 28.15

GC content: 42.83

Gene sequence:

>1116_bases
GTGATAGAAAAAAAACTCTATTCCGCGATGGAGAAGGTGTATGATCCTGAGCTCCACATACCAATCACACGCCTCGGGAT
GGTAAAAACCATAACCACAGATAGCAAAACAGTCTCAATTCTTATACATATAACATCCCCGACTTGCCCAGCGGTGGACA
AAATAAAACAAAGAGTTACCGACGCAGCTTCTGCCGTGTGCCCTGAGCACGATATAAAAATTGAAATAGGCGTTATGTCG
CACCAAGAACGTCAAAACCTGAAAGAGGTTCTCAATTTACAAAAACGCAGCAACCCGTTTAAAGAATCAAAAACAAGAAT
TATCGCTGTTACAAGCGGCAAAGGTGGAGTGGGTAAATCAACCATAGTATCTAATCTCGGTGTTGGCCTCGCGAGAATGG
GCTTTTCTGTATCAGTAATTGATGCTGATGTTTATGGTTTTTCTATACCACGAATGTTCGGCATAGATGAAGATTTTATT
CCACAGAGAGAGAATGGCATGATAATGCCTGCCAATAAATTTGGCGTTAAGCTCATTTCCATAGGAATGTTCATGCGCCG
TCGAGGGGCAGTTGCGTGGCGGGGACCGCTGCTTCACAGAACAATCAATCAATTTCTATGTGATGTGAATTTTGCTGACC
CAGATATTCTTCTAATCGATATGCCTCCCGGCACAGGAGATGCGGCAATAACTATTGCACAGTTATTGCCGAATTCTGAA
GTGCTAGTCATAACAACTCCGCAGATTGTTGCCGCTGATGTTGCAATTCGAAGTGGGCAGTTCGCCCTTTCTGTAAAACA
GAACATTATCGGTGTGGTTGAAAATATGTCATCTTGCCCGGAAAGTAAACTAGACATTTTTGGCCATGGCGGTGGTAAGT
TCGTGGCAGAATTTTTGGATAAACAATGCAAAAAAGAGAGCACCGCGAAAGATAACAGAATTACCAATCCTCATGAAGCA
ATAGATCTAATAACATGCATTCCGTTGGATGTGAATATACGCAAAAGTGGGGATGAAGGGGTGCCGCTACTCGTTGAAAA
CAAGTATGAAGGAAGCCCAGGGCATACTGCACTCAAAGAGCTTTACGAAAAAATTGCCTTGAAACTTTACGGATAA

Upstream 100 bases:

>100_bases
CAGCTAATTACAGATCAACAGAAAAACAATAACCGACTGAAGCGCCTTGAGGAGACAGAAAAAACCATACAGGACTTCGG
GAACGATTCCTGAAAAGTTT

Downstream 100 bases:

>100_bases
ACATTGCAGTAACAAGTATTCGACAGGTTTGAAAACTGCAGATAAACCGATCAGTGTGTATTCATTCCTTGCGGAAAAAC
AAACTTGCCCCGTAGTAGTC

Product: MRP family ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MIEKKLYSAMEKVYDPELHIPITRLGMVKTITTDSKTVSILIHITSPTCPAVDKIKQRVTDAASAVCPEHDIKIEIGVMS
HQERQNLKEVLNLQKRSNPFKESKTRIIAVTSGKGGVGKSTIVSNLGVGLARMGFSVSVIDADVYGFSIPRMFGIDEDFI
PQRENGMIMPANKFGVKLISIGMFMRRRGAVAWRGPLLHRTINQFLCDVNFADPDILLIDMPPGTGDAAITIAQLLPNSE
VLVITTPQIVAADVAIRSGQFALSVKQNIIGVVENMSSCPESKLDIFGHGGGKFVAEFLDKQCKKESTAKDNRITNPHEA
IDLITCIPLDVNIRKSGDEGVPLLVENKYEGSPGHTALKELYEKIALKLYG

Sequences:

>Translated_371_residues
MIEKKLYSAMEKVYDPELHIPITRLGMVKTITTDSKTVSILIHITSPTCPAVDKIKQRVTDAASAVCPEHDIKIEIGVMS
HQERQNLKEVLNLQKRSNPFKESKTRIIAVTSGKGGVGKSTIVSNLGVGLARMGFSVSVIDADVYGFSIPRMFGIDEDFI
PQRENGMIMPANKFGVKLISIGMFMRRRGAVAWRGPLLHRTINQFLCDVNFADPDILLIDMPPGTGDAAITIAQLLPNSE
VLVITTPQIVAADVAIRSGQFALSVKQNIIGVVENMSSCPESKLDIFGHGGGKFVAEFLDKQCKKESTAKDNRITNPHEA
IDLITCIPLDVNIRKSGDEGVPLLVENKYEGSPGHTALKELYEKIALKLYG
>Mature_371_residues
MIEKKLYSAMEKVYDPELHIPITRLGMVKTITTDSKTVSILIHITSPTCPAVDKIKQRVTDAASAVCPEHDIKIEIGVMS
HQERQNLKEVLNLQKRSNPFKESKTRIIAVTSGKGGVGKSTIVSNLGVGLARMGFSVSVIDADVYGFSIPRMFGIDEDFI
PQRENGMIMPANKFGVKLISIGMFMRRRGAVAWRGPLLHRTINQFLCDVNFADPDILLIDMPPGTGDAAITIAQLLPNSE
VLVITTPQIVAADVAIRSGQFALSVKQNIIGVVENMSSCPESKLDIFGHGGGKFVAEFLDKQCKKESTAKDNRITNPHEA
IDLITCIPLDVNIRKSGDEGVPLLVENKYEGSPGHTALKELYEKIALKLYG

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=270, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI157384956, Length=250, Percent_Identity=31.6, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI118572611, Length=268, Percent_Identity=31.7164179104478, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI87082045, Length=285, Percent_Identity=34.3859649122807, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25143050, Length=295, Percent_Identity=32.2033898305085, Blast_Score=117, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6322188, Length=204, Percent_Identity=41.6666666666667, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321347, Length=269, Percent_Identity=32.7137546468402, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI221511043, Length=261, Percent_Identity=34.8659003831418, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24667611, Length=202, Percent_Identity=38.1188118811881, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19921440, Length=260, Percent_Identity=33.8461538461538, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 40596; Mature: 40596

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKKLYSAMEKVYDPELHIPITRLGMVKTITTDSKTVSILIHITSPTCPAVDKIKQRVT
CCHHHHHHHHHHHCCCCCCCCHHHHCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHH
DAASAVCPEHDIKIEIGVMSHQERQNLKEVLNLQKRSNPFKESKTRIIAVTSGKGGVGKS
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHH
TIVSNLGVGLARMGFSVSVIDADVYGFSIPRMFGIDEDFIPQRENGMIMPANKFGVKLIS
HHHHHHCCHHHHHCCEEEEEEECCCCEECCHHCCCCHHCCCCCCCCEEEECHHHCHHHHH
IGMFMRRRGAVAWRGPLLHRTINQFLCDVNFADPDILLIDMPPGTGDAAITIAQLLPNSE
HHHHHHHCCCCEECCHHHHHHHHHHHEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCC
VLVITTPQIVAADVAIRSGQFALSVKQNIIGVVENMSSCPESKLDIFGHGGGKFVAEFLD
EEEEECCCEEEEHEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHH
KQCKKESTAKDNRITNPHEAIDLITCIPLDVNIRKSGDEGVPLLVENKYEGSPGHTALKE
HHHHHHCCCCCCCCCCHHHHEEEEEEEECEEEEECCCCCCCEEEEECCCCCCCCHHHHHH
LYEKIALKLYG
HHHHHHHEECC
>Mature Secondary Structure
MIEKKLYSAMEKVYDPELHIPITRLGMVKTITTDSKTVSILIHITSPTCPAVDKIKQRVT
CCHHHHHHHHHHHCCCCCCCCHHHHCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHH
DAASAVCPEHDIKIEIGVMSHQERQNLKEVLNLQKRSNPFKESKTRIIAVTSGKGGVGKS
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHH
TIVSNLGVGLARMGFSVSVIDADVYGFSIPRMFGIDEDFIPQRENGMIMPANKFGVKLIS
HHHHHHCCHHHHHCCEEEEEEECCCCEECCHHCCCCHHCCCCCCCCEEEECHHHCHHHHH
IGMFMRRRGAVAWRGPLLHRTINQFLCDVNFADPDILLIDMPPGTGDAAITIAQLLPNSE
HHHHHHHCCCCEECCHHHHHHHHHHHEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCC
VLVITTPQIVAADVAIRSGQFALSVKQNIIGVVENMSSCPESKLDIFGHGGGKFVAEFLD
EEEEECCCEEEEHEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHH
KQCKKESTAKDNRITNPHEAIDLITCIPLDVNIRKSGDEGVPLLVENKYEGSPGHTALKE
HHHHHHCCCCCCCCCCHHHHEEEEEEEECEEEEECCCCCCCEEEEECCCCCCCCHHHHHH
LYEKIALKLYG
HHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]