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The map label for this gene is ribF [H]

Identifier: 28572342

GI number: 28572342

Start: 221811

End: 222749

Strand: Direct

Name: ribF [H]

Synonym: TW180

Alternate gene names: 28572342

Gene position: 221811-222749 (Clockwise)

Preceding gene: 28572341

Following gene: 28572343

Centisome position: 23.96

GC content: 43.88

Gene sequence:

>939_bases
GTGAGGGTCTTTAGAAGTTTTGATTGCCTTGGGCGGGATAAGCGTACCGCTTTAACGATAGGGAAATTTGATGGAGTTCA
TCTCGGCCACAGGCGTTTGTTGGAAAGAATCGTAGCATTACAGAATCAGGACACATCTGCGCTTGTAGTAACTTTTGATC
GTGATCCAAAAACTTTCTTTAAAAAAGACATGTCCTTTGTGCCCCTCTGCAGTTTGGAGCAGAAGCTTTCTCTTTTAGAG
AATTGCAATATTCCTAACTGTCTTATTCTTAGATTTGATGATGAGTTTGCGTCAATGTCGGCTGAAGATTTTGTACATAA
AGTTTTGCTTGAGAAATTGAATATGTCTTCGATCGTTATTGGAGATGGGTTTCGTTTTGGCGCTCGTGGGCTTGGTGATG
CGATGCTTTTGGAGAAACTTGCGCGCGAATTGGGCTTTTATCTTGAAGTAATTCCAAAAATACAATTTGGCAAGACAAAT
ATTTCTTCGACGCTTATACGTAAATTTTTATCTCTGGGTCAAGCGGGCAATGCGTCAAGCTGCCTTGGCAGGAACCATGT
TTGTACGGGGACAGTTGTGCACGGCAAAAAGCGTGGTCGCGAATTGGGATTTCCTACTGCTAATTTAGGCAAGGACGTCT
CGGGCTTTATTCCGGCCGATGGGGTGTATATCGGCAGAATAATTTCTGACCGATCCTATCCCGCAGCGGTTTCAATAGGC
CGAAATCCAACCTTCGGTGATTTGGAATTTTCGCAAATAGAGGCCCATGCGCTTTATGAGGATATTTCCTCACTTGATCT
GTATGGCAGGCGGATTGACGTTGAGTTCATCGCGCACTTGCGAGATACCATGTTGTATAAATCTATTGACTCGTTAAAGG
CAGCCATTCGCTCTGATGTTGAGCGGTGTAAAGAGTATTTTTCCACAACCGTGGGTTGA

Upstream 100 bases:

>100_bases
CTTTCAGTAAAGCAAATGACCTTTTACGAGACCTTGGTTCCGCTCCAATTGATTGGCGTCTTACCTAATCGGGTCGAGAG
AATAATTGTAAGCGGACACT

Downstream 100 bases:

>100_bases
TATCTAGTCGTGCCCGCTTAGTCAGTCAGCGCAACACGTTTATAAGCTTCATTACACAGTCATCATTACATAACATCGGT
AACACGTTTACATATGGAGC

Product: riboflavin biosynthesis protein

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRVFRSFDCLGRDKRTALTIGKFDGVHLGHRRLLERIVALQNQDTSALVVTFDRDPKTFFKKDMSFVPLCSLEQKLSLLE
NCNIPNCLILRFDDEFASMSAEDFVHKVLLEKLNMSSIVIGDGFRFGARGLGDAMLLEKLARELGFYLEVIPKIQFGKTN
ISSTLIRKFLSLGQAGNASSCLGRNHVCTGTVVHGKKRGRELGFPTANLGKDVSGFIPADGVYIGRIISDRSYPAAVSIG
RNPTFGDLEFSQIEAHALYEDISSLDLYGRRIDVEFIAHLRDTMLYKSIDSLKAAIRSDVERCKEYFSTTVG

Sequences:

>Translated_312_residues
MRVFRSFDCLGRDKRTALTIGKFDGVHLGHRRLLERIVALQNQDTSALVVTFDRDPKTFFKKDMSFVPLCSLEQKLSLLE
NCNIPNCLILRFDDEFASMSAEDFVHKVLLEKLNMSSIVIGDGFRFGARGLGDAMLLEKLARELGFYLEVIPKIQFGKTN
ISSTLIRKFLSLGQAGNASSCLGRNHVCTGTVVHGKKRGRELGFPTANLGKDVSGFIPADGVYIGRIISDRSYPAAVSIG
RNPTFGDLEFSQIEAHALYEDISSLDLYGRRIDVEFIAHLRDTMLYKSIDSLKAAIRSDVERCKEYFSTTVG
>Mature_312_residues
MRVFRSFDCLGRDKRTALTIGKFDGVHLGHRRLLERIVALQNQDTSALVVTFDRDPKTFFKKDMSFVPLCSLEQKLSLLE
NCNIPNCLILRFDDEFASMSAEDFVHKVLLEKLNMSSIVIGDGFRFGARGLGDAMLLEKLARELGFYLEVIPKIQFGKTN
ISSTLIRKFLSLGQAGNASSCLGRNHVCTGTVVHGKKRGRELGFPTANLGKDVSGFIPADGVYIGRIISDRSYPAAVSIG
RNPTFGDLEFSQIEAHALYEDISSLDLYGRRIDVEFIAHLRDTMLYKSIDSLKAAIRSDVERCKEYFSTTVG

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Escherichia coli, GI1786208, Length=320, Percent_Identity=35.625, Blast_Score=173, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17541882, Length=121, Percent_Identity=37.1900826446281, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644927, Length=124, Percent_Identity=35.4838709677419, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 34821; Mature: 34821

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFRSFDCLGRDKRTALTIGKFDGVHLGHRRLLERIVALQNQDTSALVVTFDRDPKTFF
CCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHH
KKDMSFVPLCSLEQKLSLLENCNIPNCLILRFDDEFASMSAEDFVHKVLLEKLNMSSIVI
HCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCHHHHHHHHHHHHCCCCEEEE
GDGFRFGARGLGDAMLLEKLARELGFYLEVIPKIQFGKTNISSTLIRKFLSLGQAGNASS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
CLGRNHVCTGTVVHGKKRGRELGFPTANLGKDVSGFIPADGVYIGRIISDRSYPAAVSIG
HCCCCCCEEEEEEECHHCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEECCCCCCCEEECC
RNPTFGDLEFSQIEAHALYEDISSLDLYGRRIDVEFIAHLRDTMLYKSIDSLKAAIRSDV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERCKEYFSTTVG
HHHHHHHHHCCC
>Mature Secondary Structure
MRVFRSFDCLGRDKRTALTIGKFDGVHLGHRRLLERIVALQNQDTSALVVTFDRDPKTFF
CCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHH
KKDMSFVPLCSLEQKLSLLENCNIPNCLILRFDDEFASMSAEDFVHKVLLEKLNMSSIVI
HCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCHHHHHHHHHHHHCCCCEEEE
GDGFRFGARGLGDAMLLEKLARELGFYLEVIPKIQFGKTNISSTLIRKFLSLGQAGNASS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
CLGRNHVCTGTVVHGKKRGRELGFPTANLGKDVSGFIPADGVYIGRIISDRSYPAAVSIG
HCCCCCCEEEEEEECHHCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEECCCCCCCEEECC
RNPTFGDLEFSQIEAHALYEDISSLDLYGRRIDVEFIAHLRDTMLYKSIDSLKAAIRSDV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERCKEYFSTTVG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]