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The map label for this gene is entC [H]

Identifier: 28572232

GI number: 28572232

Start: 52002

End: 53279

Strand: Reverse

Name: entC [H]

Synonym: TW062

Alternate gene names: 28572232

Gene position: 53279-52002 (Counterclockwise)

Preceding gene: 28572236

Following gene: 28572226

Centisome position: 5.75

GC content: 43.82

Gene sequence:

>1278_bases
ATGCTTCCAATTGAAGTTGAAATAACAAGAATTGGAAATATGGATCGTAGCGACTTCAAGCGACAGTATATTCGCAAAGT
ATTGTCTTGGGATTTCGTATATTGTACACACAGCACGATGATGAGAACACAGGGCCGCGTGCTAAAAATAAATCTCGATT
CCTATTCCGCCGAGGCTAGATTTGAGGCAGCCGAGTCGCTGATAAATGAAATACATACAAAGATACAGTACACGAGCGAA
AATCTCAATCCGATTGGCCTTATCGTGCTATTCGGATTTACATTTTCGCCATATTCTGCCAGGCCGAGTTTTCTTGCAAT
ACCAGAGCAAATGTTTTTTTGGAGCGACGGGGTTGCCTGGAAAATAGATGCAACGATTTGTCATAACCTCTCGGAGCCCT
CTCGAATTTTCAAATGGCCAAAGAGTATTAGCTTTAAAATGGGAGATTTTAGACAAGAGGATTATAAACATGCCATTACC
AATGTGGTAAACAAACTTTTAAATGCAGATATATCAAAGGTAGTTTTGGCGCGGGACATTATCGCAGAAATACATGATGA
TTTTGACCCTGAAGCACACGCAATCGACCTTGATGAGGCGATACAGAGACTTATGAATACGGCAAACGGCACGGTGTTTG
TATTTGATGGACTATTCGGCGCTTCACCCGAGGTGCTGCTGAGAACAGATGGTAACTCTGGTTTTGAGGTCTCCATTCTT
GCAGGCAGCATGTCTGCCAATCACCCCAAACATGTAATACATAATTGTGCGGCAAGCCCCCCTTACAAGGCTCTCGATGA
GACATATCTCGATGAAAAGCTAAGGCTTGAACATTCCTTTGCGCTTAACCCAACCTTGGAGCGACTTAGCACACTCATGA
ACACAGCGCCAACGGTGAATTCCTACAAAATCAGGAGATTTACACACATAACCCATGTAGCGAGCTTTATATCCGGCACA
TTTAAGCCAAATATCTCCCCCTTGCGCGCATTGAGTCATATTCATCCAACAGGAGCAATTGCTGGAGAGCCCAGAGAAAG
AGCGCTGGAAATAATCAAAGAGATAGAGCCATTTGACCGCGAGCTATACGGCGGGGCAATAGGGTGGATTGGGCAAGATA
GCTCATGTGAGTTCACATTACCCATTCGATGTGCGCAGCTAAACAGGGGGCATATAAAAGCTTTTGCCGGGTGTGGAATA
GTGAAGTCAAGCATCCCGCAAAAAGAACTTGAAGAAAGCACATTAAAGTTCAAAACAATTATTGACGCAATATCCTAG

Upstream 100 bases:

>100_bases
CCCAAAGCGAAGAAAGTATAGTCCCAGGTGCAAAAACTTTACACATCGGTTTATTTTCTAAATAACAAAATACTTGAACC
GAGTTACGACGAGGGTTACC

Downstream 100 bases:

>100_bases
CGGTTCCGACTTGCTCGAATTTTCACACTCAGAATAATTGGGGATCCTGTAAAGCTGTGTTGTGAGCGTATGGACTTTTG
CAAGAATCGCCGGTAGGTTG

Product: chorismate binding enzyme

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MLPIEVEITRIGNMDRSDFKRQYIRKVLSWDFVYCTHSTMMRTQGRVLKINLDSYSAEARFEAAESLINEIHTKIQYTSE
NLNPIGLIVLFGFTFSPYSARPSFLAIPEQMFFWSDGVAWKIDATICHNLSEPSRIFKWPKSISFKMGDFRQEDYKHAIT
NVVNKLLNADISKVVLARDIIAEIHDDFDPEAHAIDLDEAIQRLMNTANGTVFVFDGLFGASPEVLLRTDGNSGFEVSIL
AGSMSANHPKHVIHNCAASPPYKALDETYLDEKLRLEHSFALNPTLERLSTLMNTAPTVNSYKIRRFTHITHVASFISGT
FKPNISPLRALSHIHPTGAIAGEPRERALEIIKEIEPFDRELYGGAIGWIGQDSSCEFTLPIRCAQLNRGHIKAFAGCGI
VKSSIPQKELEESTLKFKTIIDAIS

Sequences:

>Translated_425_residues
MLPIEVEITRIGNMDRSDFKRQYIRKVLSWDFVYCTHSTMMRTQGRVLKINLDSYSAEARFEAAESLINEIHTKIQYTSE
NLNPIGLIVLFGFTFSPYSARPSFLAIPEQMFFWSDGVAWKIDATICHNLSEPSRIFKWPKSISFKMGDFRQEDYKHAIT
NVVNKLLNADISKVVLARDIIAEIHDDFDPEAHAIDLDEAIQRLMNTANGTVFVFDGLFGASPEVLLRTDGNSGFEVSIL
AGSMSANHPKHVIHNCAASPPYKALDETYLDEKLRLEHSFALNPTLERLSTLMNTAPTVNSYKIRRFTHITHVASFISGT
FKPNISPLRALSHIHPTGAIAGEPRERALEIIKEIEPFDRELYGGAIGWIGQDSSCEFTLPIRCAQLNRGHIKAFAGCGI
VKSSIPQKELEESTLKFKTIIDAIS
>Mature_425_residues
MLPIEVEITRIGNMDRSDFKRQYIRKVLSWDFVYCTHSTMMRTQGRVLKINLDSYSAEARFEAAESLINEIHTKIQYTSE
NLNPIGLIVLFGFTFSPYSARPSFLAIPEQMFFWSDGVAWKIDATICHNLSEPSRIFKWPKSISFKMGDFRQEDYKHAIT
NVVNKLLNADISKVVLARDIIAEIHDDFDPEAHAIDLDEAIQRLMNTANGTVFVFDGLFGASPEVLLRTDGNSGFEVSIL
AGSMSANHPKHVIHNCAASPPYKALDETYLDEKLRLEHSFALNPTLERLSTLMNTAPTVNSYKIRRFTHITHVASFISGT
FKPNISPLRALSHIHPTGAIAGEPRERALEIIKEIEPFDRELYGGAIGWIGQDSSCEFTLPIRCAQLNRGHIKAFAGCGI
VKSSIPQKELEESTLKFKTIIDAIS

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=277, Percent_Identity=31.4079422382672, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787518, Length=216, Percent_Identity=27.3148148148148, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082077, Length=262, Percent_Identity=27.0992366412214, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=227, Percent_Identity=27.3127753303965, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 47810; Mature: 47810

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPIEVEITRIGNMDRSDFKRQYIRKVLSWDFVYCTHSTMMRTQGRVLKINLDSYSAEAR
CCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCEEEEEECCCCCHHH
FEAAESLINEIHTKIQYTSENLNPIGLIVLFGFTFSPYSARPSFLAIPEQMFFWSDGVAW
HHHHHHHHHHHHHHEEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCHHHEEECCCCEE
KIDATICHNLSEPSRIFKWPKSISFKMGDFRQEDYKHAITNVVNKLLNADISKVVLARDI
EEEHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAEIHDDFDPEAHAIDLDEAIQRLMNTANGTVFVFDGLFGASPEVLLRTDGNSGFEVSIL
HHHHHCCCCCCCEEECHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEE
AGSMSANHPKHVIHNCAASPPYKALDETYLDEKLRLEHSFALNPTLERLSTLMNTAPTVN
ECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
SYKIRRFTHITHVASFISGTFKPNISPLRALSHIHPTGAIAGEPRERALEIIKEIEPFDR
CEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHH
ELYGGAIGWIGQDSSCEFTLPIRCAQLNRGHIKAFAGCGIVKSSIPQKELEESTLKFKTI
HHHCCEEEECCCCCCCEEEECEEEECCCCCCEEHHHCCCHHHHCCCHHHHHHHHHHHHHH
IDAIS
HHHCC
>Mature Secondary Structure
MLPIEVEITRIGNMDRSDFKRQYIRKVLSWDFVYCTHSTMMRTQGRVLKINLDSYSAEAR
CCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCEEEEEECCCCCHHH
FEAAESLINEIHTKIQYTSENLNPIGLIVLFGFTFSPYSARPSFLAIPEQMFFWSDGVAW
HHHHHHHHHHHHHHEEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCHHHEEECCCCEE
KIDATICHNLSEPSRIFKWPKSISFKMGDFRQEDYKHAITNVVNKLLNADISKVVLARDI
EEEHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAEIHDDFDPEAHAIDLDEAIQRLMNTANGTVFVFDGLFGASPEVLLRTDGNSGFEVSIL
HHHHHCCCCCCCEEECHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEE
AGSMSANHPKHVIHNCAASPPYKALDETYLDEKLRLEHSFALNPTLERLSTLMNTAPTVN
ECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
SYKIRRFTHITHVASFISGTFKPNISPLRALSHIHPTGAIAGEPRERALEIIKEIEPFDR
CEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHH
ELYGGAIGWIGQDSSCEFTLPIRCAQLNRGHIKAFAGCGIVKSSIPQKELEESTLKFKTI
HHHCCEEEECCCCCCCEEEECEEEECCCCCCEEHHHCCCHHHHCCCHHHHHHHHHHHHHH
IDAIS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]