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The map label for this gene is tyrA [H]

Identifier: 28572230

GI number: 28572230

Start: 48827

End: 49963

Strand: Direct

Name: tyrA [H]

Synonym: TW060

Alternate gene names: 28572230

Gene position: 48827-49963 (Clockwise)

Preceding gene: 28572229

Following gene: 28572231

Centisome position: 5.27

GC content: 46.35

Gene sequence:

>1137_bases
GTGTACGTTCATATCATTGGTGCTGGACTGATTGGTGGCAGTATCGCGCTAGGTCTTTCCCGTGCAGGACTGAAGGTCAG
TGCAAGTGACATTTCGCCAGCTGCTCAGCGCCTCTCAAAACTTGGGGATATTTCGATTGGCCCGCCAAATCAGAATCCGG
ATTTGGTGTTTGTATGCACACCTCCCGATGTGACCGCCGCCGAAGTTGTGAGCTCTCTGGATAGATTTCCCGAAACTTGC
GTAGTGGATGTATCAAGCGTTAAGACCAGAATATACCGTGAGGTATTGCGTAAAACACACCCTGCAAAGCGAGTATTTTA
CATACAGAGTCATCCAATGGCTGGAAGAGAGATAGGTGGCATTCAGGGCGCCTCTGCCGATTTATTCTCAGGGTGGCCGT
GGATTGTGTGCCATTCGTTTGTTTGCGGTGACGGCAATGACCAGATGAATGGTGAGAATTCTGTTCATCAAAAGAATTAC
CTAACACGGAACACCGAAGATGAAGCGGAATGGTCTTTGGGGAAAAATCTCTTGCATTGTATAAACCTTCTAGGAGCCTT
TCCTGTCTTCATGGATAGAGACAGGCATGATCGGTCAGTTGCGGCAGTATCGCATGTGCCACATATACTCTCAAGCCTCA
TAGCCCTGTCACTTGCAAATACAGATCAAGGCACAGTTGCAATATGTGGTTCGGGTATAAAGGATATGACACGTCTTGCT
GCAAGCAATCCAGAATTGTGGACCCAGATCATTTTCTCAAATCGTCGTGAAATCTTACAAAGTCTAGGGGTTTTTTCTGG
ACTTTTGAAGAGAATGCTCCACACACTTGAGAAGCTCGATAATCCTGCGTATCGCACGGATCTGTTCTCTCAGCTTGCTG
AGGCTCAGGCCCAACAGGCCCGCATTCCAAAAAAACCGGGCAAGAATTTGGATTATTCACAGCTAGAAGTGCTTATTCCA
GACAAGCCCGGTGAGCTATCAAAGGTTTTAGGCGCTATAAACACCCAAGGTATTAACTTGGAAGATTTGCATTTTGAACA
TGCAAATAACCTCGGGGTTGTAAAGCTATCGGTATCAAACAAGGACAGGTGTCGATTGATGGACACTTTGGAAGATAAGT
GGACTTTACTAGTATAG

Upstream 100 bases:

>100_bases
CGTGGTGTTTTTACCTTACCAAGCTAATTGTCTTCTCTGCATTGATTCGCTCTTATTATTATCTGCATAGCGTAGCTGTG
TAGGTCGTACACTTTAATCG

Downstream 100 bases:

>100_bases
TTGCAATCGATGGTCCTGCCGGCAGCGGAAAAAGTTCTGTTGGTCGGGCCGTTGCTCAATATTTAGGGTATGGTTTTCTG
CCAACCGGAAGCTATTACCG

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MYVHIIGAGLIGGSIALGLSRAGLKVSASDISPAAQRLSKLGDISIGPPNQNPDLVFVCTPPDVTAAEVVSSLDRFPETC
VVDVSSVKTRIYREVLRKTHPAKRVFYIQSHPMAGREIGGIQGASADLFSGWPWIVCHSFVCGDGNDQMNGENSVHQKNY
LTRNTEDEAEWSLGKNLLHCINLLGAFPVFMDRDRHDRSVAAVSHVPHILSSLIALSLANTDQGTVAICGSGIKDMTRLA
ASNPELWTQIIFSNRREILQSLGVFSGLLKRMLHTLEKLDNPAYRTDLFSQLAEAQAQQARIPKKPGKNLDYSQLEVLIP
DKPGELSKVLGAINTQGINLEDLHFEHANNLGVVKLSVSNKDRCRLMDTLEDKWTLLV

Sequences:

>Translated_378_residues
MYVHIIGAGLIGGSIALGLSRAGLKVSASDISPAAQRLSKLGDISIGPPNQNPDLVFVCTPPDVTAAEVVSSLDRFPETC
VVDVSSVKTRIYREVLRKTHPAKRVFYIQSHPMAGREIGGIQGASADLFSGWPWIVCHSFVCGDGNDQMNGENSVHQKNY
LTRNTEDEAEWSLGKNLLHCINLLGAFPVFMDRDRHDRSVAAVSHVPHILSSLIALSLANTDQGTVAICGSGIKDMTRLA
ASNPELWTQIIFSNRREILQSLGVFSGLLKRMLHTLEKLDNPAYRTDLFSQLAEAQAQQARIPKKPGKNLDYSQLEVLIP
DKPGELSKVLGAINTQGINLEDLHFEHANNLGVVKLSVSNKDRCRLMDTLEDKWTLLV
>Mature_378_residues
MYVHIIGAGLIGGSIALGLSRAGLKVSASDISPAAQRLSKLGDISIGPPNQNPDLVFVCTPPDVTAAEVVSSLDRFPETC
VVDVSSVKTRIYREVLRKTHPAKRVFYIQSHPMAGREIGGIQGASADLFSGWPWIVCHSFVCGDGNDQMNGENSVHQKNY
LTRNTEDEAEWSLGKNLLHCINLLGAFPVFMDRDRHDRSVAAVSHVPHILSSLIALSLANTDQGTVAICGSGIKDMTRLA
ASNPELWTQIIFSNRREILQSLGVFSGLLKRMLHTLEKLDNPAYRTDLFSQLAEAQAQQARIPKKPGKNLDYSQLEVLIP
DKPGELSKVLGAINTQGINLEDLHFEHANNLGVVKLSVSNKDRCRLMDTLEDKWTLLV

Specific function: Glyoxylate catabolism. [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR002912
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01842 ACT; PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 41407; Mature: 41407

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVHIIGAGLIGGSIALGLSRAGLKVSASDISPAAQRLSKLGDISIGPPNQNPDLVFVCT
CEEEEEECCHHCCHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEC
PPDVTAAEVVSSLDRFPETCVVDVSSVKTRIYREVLRKTHPAKRVFYIQSHPMAGREIGG
CCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
IQGASADLFSGWPWIVCHSFVCGDGNDQMNGENSVHQKNYLTRNTEDEAEWSLGKNLLHC
CCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
INLLGAFPVFMDRDRHDRSVAAVSHVPHILSSLIALSLANTDQGTVAICGSGIKDMTRLA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
ASNPELWTQIIFSNRREILQSLGVFSGLLKRMLHTLEKLDNPAYRTDLFSQLAEAQAQQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RIPKKPGKNLDYSQLEVLIPDKPGELSKVLGAINTQGINLEDLHFEHANNLGVVKLSVSN
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHCCHHCCCCCEEEEEECCC
KDRCRLMDTLEDKWTLLV
CCHHHHHHHHCCCEEECC
>Mature Secondary Structure
MYVHIIGAGLIGGSIALGLSRAGLKVSASDISPAAQRLSKLGDISIGPPNQNPDLVFVCT
CEEEEEECCHHCCHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEC
PPDVTAAEVVSSLDRFPETCVVDVSSVKTRIYREVLRKTHPAKRVFYIQSHPMAGREIGG
CCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
IQGASADLFSGWPWIVCHSFVCGDGNDQMNGENSVHQKNYLTRNTEDEAEWSLGKNLLHC
CCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
INLLGAFPVFMDRDRHDRSVAAVSHVPHILSSLIALSLANTDQGTVAICGSGIKDMTRLA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
ASNPELWTQIIFSNRREILQSLGVFSGLLKRMLHTLEKLDNPAYRTDLFSQLAEAQAQQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RIPKKPGKNLDYSQLEVLIPDKPGELSKVLGAINTQGINLEDLHFEHANNLGVVKLSVSN
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHCCHHCCCCCEEEEEECCC
KDRCRLMDTLEDKWTLLV
CCHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA