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The map label for this gene is puuP [H]

Identifier: 28379371

GI number: 28379371

Start: 2598108

End: 2599475

Strand: Direct

Name: puuP [H]

Synonym: lp_2920

Alternate gene names: 28379371

Gene position: 2598108-2599475 (Clockwise)

Preceding gene: 28379370

Following gene: 28379375

Centisome position: 78.53

GC content: 40.42

Gene sequence:

>1368_bases
ATGGATTTAAAACACACCCCTAGTTCATCTAATACTAACCTTGACGAATTTGGCTATCAACAAGAATTAAAACGAACACT
ATCTGTTAAAGATTTGGTTATTTACGGCCTAATCTTTATGGTGCCAATCGCACCAATGGGGATTTATGGCGCTGTTATTT
CGGTTTCACAAGGTATGATTGCGTTGACCTATGCCATTGGGATGCTGGCGATGTTCTTTACCGCTCTCAGCTACGGACAA
ATGTCACAGGCCTTTCCCGTGGCTGGATCAGTTTATGCCTATGCAAAACTTGGCATCAATAAATCAATTGGTTTTCTGTC
TGGTTGGATGATTATTTTAGATTATATCTTTGTCCCCGCATTACTCTACATCATCGCTGCCAATTCATTAAAATCCCTCC
TACCAACCATTCCAACTTGGCTATGGCTGGTTGGTTTTATTGCAATCAATACCCTTATTAATGTTGGAGGCATTGCCTTC
ACTGCTATTGCAAATCGAATTTTTCTCATTGGTGAATTAATTGTACTTGCTTTTTTCATTATCCTCGGGAGCTATGGCTT
AATGCGGGGAATTGGAAATGGTTTCACACTAAAACCATTTTATGACGCAAGTCACTTTAATCTTAATTTTGTCATGACAG
CCACTTCAGTAGCAGTTCTCAGCTTTTTAGGTTTCGACGGCATTAGTACCCTAGCGGAAGAAACCACTGGTGGTAATCAG
GCTGTGGGAAAAGGTATCCTATGGTCGCTATTAATTGTAGGCGCATTATTCATCATTCAGACTTACTTAGCTGCTCTAAT
CGTTCCTAACTGGCATTCTTTTAACGATCTAAATACTGCATTTTACGTCGTCGCCGGCAAGGTCGGTGGCCCATTCCTAA
CTGATTTAACCACTATTGCCACCATTCTCTCTTGGGGATTTGCCAATGCATTAGCTGCCCAAGCTGCAATTTCACGAATC
CTATTCGGAATGGCCCGTGACCACAATTTGCCACACGTTCTTGCCCGTGTACATCCCCGATTCAAGACCCCATATATGAG
TACTTTACTAGTAGCTATTATTTCACTGCTTGTCGGGTTAACTTTTATGAATGACAGTGGGACACTCTCTGAAATCGTCA
ATTGTGGTGCCCTGACCGCTTTTCTAGTGATTCATATTGCCGTTATTAACCACTTCTTTATCAAGCAACATTCCCATGAC
TATTGGCATCATCTCATTGTACCAATTATCGGTTTTATCATTATTGGCTTCGTTATGATTAATTTAAACGTATTAGCAAA
AGAAATTGGCGGAATTTGGTTACTTATTGGTATTGGCTACTATCTCATCTTGCGTGTATTACAGCGGAATACGGAAATGA
ATTTATAA

Upstream 100 bases:

>100_bases
CAACGCCAGCAACCACAGTGCCACTTTATGGAAACATCTACGCTCACTCGTTTACCATCTCAATGCCCTGACTTTATGCC
ATACTGAGGAGAAATTGCCT

Downstream 100 bases:

>100_bases
CTCATGATGGTCTGAGCTTGAGCAACGTAAAAAGAACTTCTCCAAATTAGAAGAAGTTCTTTTTACATGATATAAAACAA
CCCCTGGCTTAAACCGACTT

Product: amino acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MDLKHTPSSSNTNLDEFGYQQELKRTLSVKDLVIYGLIFMVPIAPMGIYGAVISVSQGMIALTYAIGMLAMFFTALSYGQ
MSQAFPVAGSVYAYAKLGINKSIGFLSGWMIILDYIFVPALLYIIAANSLKSLLPTIPTWLWLVGFIAINTLINVGGIAF
TAIANRIFLIGELIVLAFFIILGSYGLMRGIGNGFTLKPFYDASHFNLNFVMTATSVAVLSFLGFDGISTLAEETTGGNQ
AVGKGILWSLLIVGALFIIQTYLAALIVPNWHSFNDLNTAFYVVAGKVGGPFLTDLTTIATILSWGFANALAAQAAISRI
LFGMARDHNLPHVLARVHPRFKTPYMSTLLVAIISLLVGLTFMNDSGTLSEIVNCGALTAFLVIHIAVINHFFIKQHSHD
YWHHLIVPIIGFIIIGFVMINLNVLAKEIGGIWLLIGIGYYLILRVLQRNTEMNL

Sequences:

>Translated_455_residues
MDLKHTPSSSNTNLDEFGYQQELKRTLSVKDLVIYGLIFMVPIAPMGIYGAVISVSQGMIALTYAIGMLAMFFTALSYGQ
MSQAFPVAGSVYAYAKLGINKSIGFLSGWMIILDYIFVPALLYIIAANSLKSLLPTIPTWLWLVGFIAINTLINVGGIAF
TAIANRIFLIGELIVLAFFIILGSYGLMRGIGNGFTLKPFYDASHFNLNFVMTATSVAVLSFLGFDGISTLAEETTGGNQ
AVGKGILWSLLIVGALFIIQTYLAALIVPNWHSFNDLNTAFYVVAGKVGGPFLTDLTTIATILSWGFANALAAQAAISRI
LFGMARDHNLPHVLARVHPRFKTPYMSTLLVAIISLLVGLTFMNDSGTLSEIVNCGALTAFLVIHIAVINHFFIKQHSHD
YWHHLIVPIIGFIIIGFVMINLNVLAKEIGGIWLLIGIGYYLILRVLQRNTEMNL
>Mature_455_residues
MDLKHTPSSSNTNLDEFGYQQELKRTLSVKDLVIYGLIFMVPIAPMGIYGAVISVSQGMIALTYAIGMLAMFFTALSYGQ
MSQAFPVAGSVYAYAKLGINKSIGFLSGWMIILDYIFVPALLYIIAANSLKSLLPTIPTWLWLVGFIAINTLINVGGIAF
TAIANRIFLIGELIVLAFFIILGSYGLMRGIGNGFTLKPFYDASHFNLNFVMTATSVAVLSFLGFDGISTLAEETTGGNQ
AVGKGILWSLLIVGALFIIQTYLAALIVPNWHSFNDLNTAFYVVAGKVGGPFLTDLTTIATILSWGFANALAAQAAISRI
LFGMARDHNLPHVLARVHPRFKTPYMSTLLVAIISLLVGLTFMNDSGTLSEIVNCGALTAFLVIHIAVINHFFIKQHSHD
YWHHLIVPIIGFIIIGFVMINLNVLAKEIGGIWLLIGIGYYLILRVLQRNTEMNL

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=418, Percent_Identity=23.2057416267943, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081869, Length=435, Percent_Identity=32.4137931034483, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI87082023, Length=445, Percent_Identity=31.2359550561798, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87081708, Length=425, Percent_Identity=23.2941176470588, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786302, Length=345, Percent_Identity=23.768115942029, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=408, Percent_Identity=23.0392156862745, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17533459, Length=406, Percent_Identity=22.4137931034483, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666159, Length=429, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221512776, Length=436, Percent_Identity=22.9357798165138, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668806, Length=398, Percent_Identity=22.3618090452261, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356285, Length=398, Percent_Identity=22.3618090452261, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24668802, Length=398, Percent_Identity=22.3618090452261, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281366235, Length=412, Percent_Identity=23.0582524271845, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI116007820, Length=412, Percent_Identity=23.0582524271845, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49675; Mature: 49675

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]