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The map label for this gene is gmuR [H]

Identifier: 28379375

GI number: 28379375

Start: 2603353

End: 2604072

Strand: Direct

Name: gmuR [H]

Synonym: lp_2924

Alternate gene names: 28379375

Gene position: 2603353-2604072 (Clockwise)

Preceding gene: 28379371

Following gene: 28379383

Centisome position: 78.69

GC content: 45.42

Gene sequence:

>720_bases
ATGGGGAAACAAACATTCAGCGACATCTATCACGTTTTAAAGGACCGCATTCTCACGGGACACTACAGCGTTAAGATGCG
ATTACCCATTGAAGACGAATTAATTACAGAATTTGATAGCAGTCGCTATGCTGTTCGTAAGGCAATCGCACAACTAGCCA
AAGACGGCCTAGTTTACAGCGTTAAGGGGCGCGGGGTGGTCTTATTGGAGCACACGCCACAAACCCAGCAATTCAATCTG
GCTTTAAATAATCTCAACGGTCTGCAGAGCCTCAACGCGGAGCGCCACCTCGATTATCAGACCGAGGTCGTGGCCTTTCA
GCAACGAATCGTTGACCAGCCGCTTAGCACACATACCGCTTTTGAAGTGGGTATTCCAGTGTATGCTATTCAACGGGTTC
GGATCGTAGACGGTATTCGGGCAGTGCTGGACATTAACTATTTTAACGCCCAGCGCACTCCCACTCTGACTAAGACCATT
GCCCAACACTCAATTTATCAACACTTCAAAAAAAATGGTCTGAAAATTGCTGTCGTTAAAAGAATGCTACGAGTCGAATC
CGCCAACGAACTCGACAAAGCTCAGCTAGCGCTCGGTGATAATAATTGCGTCGGTAATATGATTAGCATCGCATTTAACG
ATGAAGGACGCCAGGTTGAATACACTGAATCCCACTTTATTCCGAACGAATTTAACTTCAATGAATTAATTCGTAATTAA

Upstream 100 bases:

>100_bases
TTTTATTCGAATAAATATCGATATTTATTCGCTTGTTTACTCGCTAATGACTATTATTTGCTATAATTAAATTAATTATA
TGATGAGCGGGGGTATTAAA

Downstream 100 bases:

>100_bases
ACCTTACCAACATTACTTAGCTGAATGGTCATCCGGACCATCCAGCTTTTTATTATGGTTACTTACTTTAGACCAATTCA
GTCGGTCAATTAAATTTATC

Product: transcription regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MGKQTFSDIYHVLKDRILTGHYSVKMRLPIEDELITEFDSSRYAVRKAIAQLAKDGLVYSVKGRGVVLLEHTPQTQQFNL
ALNNLNGLQSLNAERHLDYQTEVVAFQQRIVDQPLSTHTAFEVGIPVYAIQRVRIVDGIRAVLDINYFNAQRTPTLTKTI
AQHSIYQHFKKNGLKIAVVKRMLRVESANELDKAQLALGDNNCVGNMISIAFNDEGRQVEYTESHFIPNEFNFNELIRN

Sequences:

>Translated_239_residues
MGKQTFSDIYHVLKDRILTGHYSVKMRLPIEDELITEFDSSRYAVRKAIAQLAKDGLVYSVKGRGVVLLEHTPQTQQFNL
ALNNLNGLQSLNAERHLDYQTEVVAFQQRIVDQPLSTHTAFEVGIPVYAIQRVRIVDGIRAVLDINYFNAQRTPTLTKTI
AQHSIYQHFKKNGLKIAVVKRMLRVESANELDKAQLALGDNNCVGNMISIAFNDEGRQVEYTESHFIPNEFNFNELIRN
>Mature_238_residues
GKQTFSDIYHVLKDRILTGHYSVKMRLPIEDELITEFDSSRYAVRKAIAQLAKDGLVYSVKGRGVVLLEHTPQTQQFNLA
LNNLNGLQSLNAERHLDYQTEVVAFQQRIVDQPLSTHTAFEVGIPVYAIQRVRIVDGIRAVLDINYFNAQRTPTLTKTIA
QHSIYQHFKKNGLKIAVVKRMLRVESANELDKAQLALGDNNCVGNMISIAFNDEGRQVEYTESHFIPNEFNFNELIRN

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=238, Percent_Identity=23.5294117647059, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27261; Mature: 27129

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKQTFSDIYHVLKDRILTGHYSVKMRLPIEDELITEFDSSRYAVRKAIAQLAKDGLVYS
CCCHHHHHHHHHHHHHEEECCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCEEE
VKGRGVVLLEHTPQTQQFNLALNNLNGLQSLNAERHLDYQTEVVAFQQRIVDQPLSTHTA
ECCCEEEEEECCCCCCEEEEEECCCCCHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCE
FEVGIPVYAIQRVRIVDGIRAVLDINYFNAQRTPTLTKTIAQHSIYQHFKKNGLKIAVVK
EEECCCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHH
RMLRVESANELDKAQLALGDNNCVGNMISIAFNDEGRQVEYTESHFIPNEFNFNELIRN
HHHHHHCCCCCCHHHEEECCCCCCCCEEEEEECCCCCEEEEHHHCCCCCCCCHHHHHCC
>Mature Secondary Structure 
GKQTFSDIYHVLKDRILTGHYSVKMRLPIEDELITEFDSSRYAVRKAIAQLAKDGLVYS
CCHHHHHHHHHHHHHEEECCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCEEE
VKGRGVVLLEHTPQTQQFNLALNNLNGLQSLNAERHLDYQTEVVAFQQRIVDQPLSTHTA
ECCCEEEEEECCCCCCEEEEEECCCCCHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCE
FEVGIPVYAIQRVRIVDGIRAVLDINYFNAQRTPTLTKTIAQHSIYQHFKKNGLKIAVVK
EEECCCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHH
RMLRVESANELDKAQLALGDNNCVGNMISIAFNDEGRQVEYTESHFIPNEFNFNELIRN
HHHHHHCCCCCCHHHEEECCCCCCCCEEEEEECCCCCEEEEHHHCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]