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The map label for this gene is ltaS1 [H]

Identifier: 28379111

GI number: 28379111

Start: 2298515

End: 2300527

Strand: Direct

Name: ltaS1 [H]

Synonym: lp_2580

Alternate gene names: 28379111

Gene position: 2298515-2300527 (Clockwise)

Preceding gene: 28379108

Following gene: 28379112

Centisome position: 69.48

GC content: 42.67

Gene sequence:

>2013_bases
ATGCTCGTGAACCCGATTGCAACGACGGTCTTTCTGTTTAGTCTGGCGTTCTACATTCGTAAAACCGGTGTATATTACTA
TATTTTGCTATTCATTGATGCACTCGACACCATTTTACTGTATGCCAACGTTATCTACCATCGTGAATTCACGGATTTCA
TGACTGTTAGTACGATTACCGGCGTGTCCAAGGTCAGTCAGGGACTTACCGGCTCATCGTTAGCCCTAGCGAGTTGGGGC
GATGTTCTTTACTGGGCGGATATTATTGTCATTCTGGCCTTGGTCATTCTTCATCGGATTGAGCAAGACACACGACCAAT
TAAGAAACACACGGCCTTTGCGTACACCTCTGCCGCGATTGCAGGTTTCGGTCTTAACTTGACCTTAGCAGAATCCAACC
GACCACAACTACTAACCAGAACGTTTGACCGCACTTATATCGTCAAATATCTTGGTATAGATGCTTTTACAGTCTATGAT
GGTATCAAGGATGAACAGACCAATCATCAACGCGCCAGCGCAAAGAAATCAGAATTAGATACCGTTAAAGATTATACTGA
ATCACACTATGCCGCGCCAAACGCTAAGATGTACGGTCTGGCGAAGGGTCGCAACGTCATTGTGATTCATCTAGAAAGTT
TTCAACAATTTCTTATTGATCAGAAAGTCAACGGTAAGGAAGTTACGCCGTTCTTAAATAAACTGTATCATAGCAACTCA
ACTTACAGTTTTAAGAACTTTTTCCACCAAGTTGGTCAAGGGAAAACTTCTGATGCCGAAAATATGCTTGAAACTAGTAC
TTACGGGCTCTCAACTGGATCATTGTTCTCCCAATTAGGCTCAGATAATACGTTCCAGGCCGCTCCCGCGATTCTAAACC
AACGGGCCAATTATTCCTCCGCCGTCTTCCACGGTAACGTGGCCAGTTTCTGGAATCGAAATAACACGTATAAGAATATG
GGGTACCAATATTTCTTTGATGCCAGTTATTTCGATACGACTGGTGATAAATCAACTGGATATGGTCTAAAGGATAAGCT
GTTATTTAAGAATTCAGTTCAGTATCTTGAACGGCTACAACAACCGTTCTACGTCAAATACATCACGGTAACGAACCACT
TCCCATTCACACTTGATAAGGAAGACACGACGTTTAAGACAACGGATACTAGTGATTCCGCCATTAACGGTTACTTCCAG
ACCGCCCACTACCTCGATCAATCCGTCAAAGAATTCTATACCTACTTGCAAAAGGCTGGTTTATTAAAGAATTCGATGAT
CGTACTCTATGGTGACCACTACGGCTTATCCAACAGTGAAAACTCGACCTTGGCACCTATTCTTGGTAAATCTGCGGACG
ATTGGACTTCCTTTGATAGCGCCCAGCTTCAACGTGTGCCATTCATGATCAATATTCCAGGAATCAAGAGTGGTAAAGTC
GAATCGACTTATGGCGGTGAAATTGACGTCCTACCAACGATTCTGCACTTACTAGGGATTTCAAGCAAACGTTATATTCA
GTTTGGGACCGACCTCTTCTCTAAACAACACGATAGTACCGTTGCGTTTAGAAATCGCGATTTCGTCACGTCTAAATACA
CCGTCCTTAGCGGCAAAATTTATGACAACGCAACTGGCGAAACGATTGATGATGATGAGGCAGTTCAGAAGACTGTTGAT
AAAGATCAGAAGAAAGTCGACAAAGAATTAAGCCTCTCTGATTCACTTAACAATAAAAATTTGTTACGTTTCTACACCCC
TAAGGGCTTCAAGAAAGTCGACGCTTCTAATTACAATTACGCCGATGGCCTTGAAAAAGAAATTCAGATTCAAAATAAAT
TAGCTGGCAAGTCAACCAGTCTCTACTCGAAGAATGGTAATAAGTCAACGGACTCGTTGTATACGACCGACGCACCGGAA
GCTTCGCATAAGAAGACTGATTCTACTCGTATCAAGATTACCAACCCTGATGATACGGATAGTACCACGACTAGCTCTAG
CAGTTCCAAATAG

Upstream 100 bases:

>100_bases
ATTTTTTTGGCTACTAGTCTTCTTATTCTGGGCCAAAACGATCTATGCGTACTTAACCGAATTTTCACTAGGCGTTGCCG
ATCCACTCCAGGCATTCCTG

Downstream 100 bases:

>100_bases
CAACAAGCATTCCATTTACAATGCAAGGCGCGACGGCAATTTATTTGCCATCGCGCCTTTTTATGATCTCCTTTAAATAT
GACGCTGCCCTCATCCATCT

Product: alkaline phosphatase superfamily protein

Products: NA

Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MLVNPIATTVFLFSLAFYIRKTGVYYYILLFIDALDTILLYANVIYHREFTDFMTVSTITGVSKVSQGLTGSSLALASWG
DVLYWADIIVILALVILHRIEQDTRPIKKHTAFAYTSAAIAGFGLNLTLAESNRPQLLTRTFDRTYIVKYLGIDAFTVYD
GIKDEQTNHQRASAKKSELDTVKDYTESHYAAPNAKMYGLAKGRNVIVIHLESFQQFLIDQKVNGKEVTPFLNKLYHSNS
TYSFKNFFHQVGQGKTSDAENMLETSTYGLSTGSLFSQLGSDNTFQAAPAILNQRANYSSAVFHGNVASFWNRNNTYKNM
GYQYFFDASYFDTTGDKSTGYGLKDKLLFKNSVQYLERLQQPFYVKYITVTNHFPFTLDKEDTTFKTTDTSDSAINGYFQ
TAHYLDQSVKEFYTYLQKAGLLKNSMIVLYGDHYGLSNSENSTLAPILGKSADDWTSFDSAQLQRVPFMINIPGIKSGKV
ESTYGGEIDVLPTILHLLGISSKRYIQFGTDLFSKQHDSTVAFRNRDFVTSKYTVLSGKIYDNATGETIDDDEAVQKTVD
KDQKKVDKELSLSDSLNNKNLLRFYTPKGFKKVDASNYNYADGLEKEIQIQNKLAGKSTSLYSKNGNKSTDSLYTTDAPE
ASHKKTDSTRIKITNPDDTDSTTTSSSSSK

Sequences:

>Translated_670_residues
MLVNPIATTVFLFSLAFYIRKTGVYYYILLFIDALDTILLYANVIYHREFTDFMTVSTITGVSKVSQGLTGSSLALASWG
DVLYWADIIVILALVILHRIEQDTRPIKKHTAFAYTSAAIAGFGLNLTLAESNRPQLLTRTFDRTYIVKYLGIDAFTVYD
GIKDEQTNHQRASAKKSELDTVKDYTESHYAAPNAKMYGLAKGRNVIVIHLESFQQFLIDQKVNGKEVTPFLNKLYHSNS
TYSFKNFFHQVGQGKTSDAENMLETSTYGLSTGSLFSQLGSDNTFQAAPAILNQRANYSSAVFHGNVASFWNRNNTYKNM
GYQYFFDASYFDTTGDKSTGYGLKDKLLFKNSVQYLERLQQPFYVKYITVTNHFPFTLDKEDTTFKTTDTSDSAINGYFQ
TAHYLDQSVKEFYTYLQKAGLLKNSMIVLYGDHYGLSNSENSTLAPILGKSADDWTSFDSAQLQRVPFMINIPGIKSGKV
ESTYGGEIDVLPTILHLLGISSKRYIQFGTDLFSKQHDSTVAFRNRDFVTSKYTVLSGKIYDNATGETIDDDEAVQKTVD
KDQKKVDKELSLSDSLNNKNLLRFYTPKGFKKVDASNYNYADGLEKEIQIQNKLAGKSTSLYSKNGNKSTDSLYTTDAPE
ASHKKTDSTRIKITNPDDTDSTTTSSSSSK
>Mature_670_residues
MLVNPIATTVFLFSLAFYIRKTGVYYYILLFIDALDTILLYANVIYHREFTDFMTVSTITGVSKVSQGLTGSSLALASWG
DVLYWADIIVILALVILHRIEQDTRPIKKHTAFAYTSAAIAGFGLNLTLAESNRPQLLTRTFDRTYIVKYLGIDAFTVYD
GIKDEQTNHQRASAKKSELDTVKDYTESHYAAPNAKMYGLAKGRNVIVIHLESFQQFLIDQKVNGKEVTPFLNKLYHSNS
TYSFKNFFHQVGQGKTSDAENMLETSTYGLSTGSLFSQLGSDNTFQAAPAILNQRANYSSAVFHGNVASFWNRNNTYKNM
GYQYFFDASYFDTTGDKSTGYGLKDKLLFKNSVQYLERLQQPFYVKYITVTNHFPFTLDKEDTTFKTTDTSDSAINGYFQ
TAHYLDQSVKEFYTYLQKAGLLKNSMIVLYGDHYGLSNSENSTLAPILGKSADDWTSFDSAQLQRVPFMINIPGIKSGKV
ESTYGGEIDVLPTILHLLGISSKRYIQFGTDLFSKQHDSTVAFRNRDFVTSKYTVLSGKIYDNATGETIDDDEAVQKTVD
KDQKKVDKELSLSDSLNNKNLLRFYTPKGFKKVDASNYNYADGLEKEIQIQNKLAGKSTSLYSKNGNKSTDSLYTTDAPE
ASHKKTDSTRIKITNPDDTDSTTTSSSSSK

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 75267; Mature: 75267

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNPIATTVFLFSLAFYIRKTGVYYYILLFIDALDTILLYANVIYHREFTDFMTVSTIT
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSKVSQGLTGSSLALASWGDVLYWADIIVILALVILHRIEQDTRPIKKHTAFAYTSAAI
HHHHHHCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AGFGLNLTLAESNRPQLLTRTFDRTYIVKYLGIDAFTVYDGIKDEQTNHQRASAKKSELD
HHCCEEEEEECCCCCCHHHHHHCHHEEEHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHH
TVKDYTESHYAAPNAKMYGLAKGRNVIVIHLESFQQFLIDQKVNGKEVTPFLNKLYHSNS
HHHHHHHHHCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCCC
TYSFKNFFHQVGQGKTSDAENMLETSTYGLSTGSLFSQLGSDNTFQAAPAILNQRANYSS
CCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
AVFHGNVASFWNRNNTYKNMGYQYFFDASYFDTTGDKSTGYGLKDKLLFKNSVQYLERLQ
EEEECCHHHHHCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
QPFYVKYITVTNHFPFTLDKEDTTFKTTDTSDSAINGYFQTAHYLDQSVKEFYTYLQKAG
CCEEEEEEEEECCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLKNSMIVLYGDHYGLSNSENSTLAPILGKSADDWTSFDSAQLQRVPFMINIPGIKSGKV
CCCCCEEEEEECCCCCCCCCCCEECHHHCCCCCCCCCCCCHHHHHCCEEEECCCCCCCCC
ESTYGGEIDVLPTILHLLGISSKRYIQFGTDLFSKQHDSTVAFRNRDFVTSKYTVLSGKI
CCCCCCCEEHHHHHHHHHCCCCCCEEEECHHHHHCCCCCEEEECCCCCEEEEEEEEECEE
YDNATGETIDDDEAVQKTVDKDQKKVDKELSLSDSLNNKNLLRFYTPKGFKKVDASNYNY
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHCCCCCCCEEEEECCCCCEECCCCCCCC
ADGLEKEIQIQNKLAGKSTSLYSKNGNKSTDSLYTTDAPEASHKKTDSTRIKITNPDDTD
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCC
STTTSSSSSK
CCCCCCCCCC
>Mature Secondary Structure
MLVNPIATTVFLFSLAFYIRKTGVYYYILLFIDALDTILLYANVIYHREFTDFMTVSTIT
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSKVSQGLTGSSLALASWGDVLYWADIIVILALVILHRIEQDTRPIKKHTAFAYTSAAI
HHHHHHCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AGFGLNLTLAESNRPQLLTRTFDRTYIVKYLGIDAFTVYDGIKDEQTNHQRASAKKSELD
HHCCEEEEEECCCCCCHHHHHHCHHEEEHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHH
TVKDYTESHYAAPNAKMYGLAKGRNVIVIHLESFQQFLIDQKVNGKEVTPFLNKLYHSNS
HHHHHHHHHCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCCC
TYSFKNFFHQVGQGKTSDAENMLETSTYGLSTGSLFSQLGSDNTFQAAPAILNQRANYSS
CCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
AVFHGNVASFWNRNNTYKNMGYQYFFDASYFDTTGDKSTGYGLKDKLLFKNSVQYLERLQ
EEEECCHHHHHCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
QPFYVKYITVTNHFPFTLDKEDTTFKTTDTSDSAINGYFQTAHYLDQSVKEFYTYLQKAG
CCEEEEEEEEECCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLKNSMIVLYGDHYGLSNSENSTLAPILGKSADDWTSFDSAQLQRVPFMINIPGIKSGKV
CCCCCEEEEEECCCCCCCCCCCEECHHHCCCCCCCCCCCCHHHHHCCEEEECCCCCCCCC
ESTYGGEIDVLPTILHLLGISSKRYIQFGTDLFSKQHDSTVAFRNRDFVTSKYTVLSGKI
CCCCCCCEEHHHHHHHHHCCCCCCEEEECHHHHHCCCCCEEEECCCCCEEEEEEEEECEE
YDNATGETIDDDEAVQKTVDKDQKKVDKELSLSDSLNNKNLLRFYTPKGFKKVDASNYNY
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHCCCCCCCEEEEECCCCCEECCCCCCCC
ADGLEKEIQIQNKLAGKSTSLYSKNGNKSTDSLYTTDAPEASHKKTDSTRIKITNPDDTD
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCC
STTTSSSSSK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377; 10658653 [H]