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The map label for this gene is ywbI [H]

Identifier: 28378374

GI number: 28378374

Start: 1533671

End: 1534558

Strand: Direct

Name: ywbI [H]

Synonym: lp_1685

Alternate gene names: 28378374

Gene position: 1533671-1534558 (Clockwise)

Preceding gene: 28378372

Following gene: 28378375

Centisome position: 46.36

GC content: 44.59

Gene sequence:

>888_bases
ATGGAAACACGGAAATTGGCAGTGTTTGTTGACCTTGCCACGACCCAGAACTATAGTCGCAGTGCTGAACGCATGTTTTT
GTCACAGTCGACCATTTCAAAGTACATTATGGCTTTAGAGCGCGATTGGCAGGTCCAATTATTTGAACGTGCGCATCGGC
AAGTCACGTTAACACGGATTGGGCAACAATTATTGCCACGGGCCCAAGCAATTCTGCGCGAAGAGCGTCAGTTACAACAA
GTTCTGGCCGCTAATACCGCTCATAATGCGCAGTCGCTGGTTGTTCAGGGACTACCATCTTTAGCACAATACCAGGCTTT
TCATATTATCACGGCATTTACGAAGCGGTATCCGGAAGTGAAATTACAATTTAGTGAGGCGAGTGTCGATCGGTTAGCGC
ATGCACTGGATCATACGAATGTCGACATTGTATTTACACGGATTTTCGGGGATCAACCCAATAATTATGACGTTTTATTG
AATGAGACCGATCAGTTTGTGGTCCTTGTTCCGAAAGACGATCCGTTGGCGCAACAAGCTGAGATTAGTCTGTCGATGCT
GGCACATGAATCAATTTTATTATTGAAAGATACCATCGGTGAAGATAACCCGTTGTTTTCGGCATTTCAAAAAATGCATA
CGCCACAGATGGTCTATGATGGTCAACGAATTGATCTCATTTTAGAAATGCTGAATCAGGGTGATGGTGTCTCGGTTGTC
ATGGCGCGGTCATTTGATCTCACTGGTTTTGACAACATTAAAGCAATTCCACTGACGCCTACTATTCGCAGTCAGATGGC
TTTCATGAAACGTCCAGATAATCACGCTGCCGTGGTTGCTAAATTTTGGGCGTTTGCGACGAAGTATAGCCAATCACTTT
CAGATTAA

Upstream 100 bases:

>100_bases
TAAAAACAACAGCTATTAGTTTAGAGCTTGTTTCGGATAAGAACAATTCTGAATATGTGGTAAACTATTCTAAATAGGAA
TAGTTAGAAGAGGGTTAATT

Downstream 100 bases:

>100_bases
TTGTGGCGGCTGATCACATTCTAACGATGTGTCTTGAATCGGAATCAAAGCCGACGATGACATAAGGATAAAAGCAGTCG
GTTTCGGTGGTCGTAGCAGG

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
METRKLAVFVDLATTQNYSRSAERMFLSQSTISKYIMALERDWQVQLFERAHRQVTLTRIGQQLLPRAQAILREERQLQQ
VLAANTAHNAQSLVVQGLPSLAQYQAFHIITAFTKRYPEVKLQFSEASVDRLAHALDHTNVDIVFTRIFGDQPNNYDVLL
NETDQFVVLVPKDDPLAQQAEISLSMLAHESILLLKDTIGEDNPLFSAFQKMHTPQMVYDGQRIDLILEMLNQGDGVSVV
MARSFDLTGFDNIKAIPLTPTIRSQMAFMKRPDNHAAVVAKFWAFATKYSQSLSD

Sequences:

>Translated_295_residues
METRKLAVFVDLATTQNYSRSAERMFLSQSTISKYIMALERDWQVQLFERAHRQVTLTRIGQQLLPRAQAILREERQLQQ
VLAANTAHNAQSLVVQGLPSLAQYQAFHIITAFTKRYPEVKLQFSEASVDRLAHALDHTNVDIVFTRIFGDQPNNYDVLL
NETDQFVVLVPKDDPLAQQAEISLSMLAHESILLLKDTIGEDNPLFSAFQKMHTPQMVYDGQRIDLILEMLNQGDGVSVV
MARSFDLTGFDNIKAIPLTPTIRSQMAFMKRPDNHAAVVAKFWAFATKYSQSLSD
>Mature_295_residues
METRKLAVFVDLATTQNYSRSAERMFLSQSTISKYIMALERDWQVQLFERAHRQVTLTRIGQQLLPRAQAILREERQLQQ
VLAANTAHNAQSLVVQGLPSLAQYQAFHIITAFTKRYPEVKLQFSEASVDRLAHALDHTNVDIVFTRIFGDQPNNYDVLL
NETDQFVVLVPKDDPLAQQAEISLSMLAHESILLLKDTIGEDNPLFSAFQKMHTPQMVYDGQRIDLILEMLNQGDGVSVV
MARSFDLTGFDNIKAIPLTPTIRSQMAFMKRPDNHAAVVAKFWAFATKYSQSLSD

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=25, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790399, Length=277, Percent_Identity=23.826714801444, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787530, Length=236, Percent_Identity=26.6949152542373, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=26.2237762237762, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787879, Length=288, Percent_Identity=24.6527777777778, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082132, Length=171, Percent_Identity=27.4853801169591, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=24.1496598639456, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788296, Length=230, Percent_Identity=26.5217391304348, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33501; Mature: 33501

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRKLAVFVDLATTQNYSRSAERMFLSQSTISKYIMALERDWQVQLFERAHRQVTLTRI
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEHHHHH
GQQLLPRAQAILREERQLQQVLAANTAHNAQSLVVQGLPSLAQYQAFHIITAFTKRYPEV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCE
KLQFSEASVDRLAHALDHTNVDIVFTRIFGDQPNNYDVLLNETDQFVVLVPKDDPLAQQA
EEEECHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCHHH
EISLSMLAHESILLLKDTIGEDNPLFSAFQKMHTPQMVYDGQRIDLILEMLNQGDGVSVV
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCEEEE
MARSFDLTGFDNIKAIPLTPTIRSQMAFMKRPDNHAAVVAKFWAFATKYSQSLSD
EEEECCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METRKLAVFVDLATTQNYSRSAERMFLSQSTISKYIMALERDWQVQLFERAHRQVTLTRI
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEHHHHH
GQQLLPRAQAILREERQLQQVLAANTAHNAQSLVVQGLPSLAQYQAFHIITAFTKRYPEV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCE
KLQFSEASVDRLAHALDHTNVDIVFTRIFGDQPNNYDVLLNETDQFVVLVPKDDPLAQQA
EEEECHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCHHH
EISLSMLAHESILLLKDTIGEDNPLFSAFQKMHTPQMVYDGQRIDLILEMLNQGDGVSVV
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCEEEE
MARSFDLTGFDNIKAIPLTPTIRSQMAFMKRPDNHAAVVAKFWAFATKYSQSLSD
EEEECCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]