Click here to switch to the map view.

The map label for this gene is rpe [H]

Identifier: 28378321

GI number: 28378321

Start: 1476334

End: 1476987

Strand: Direct

Name: rpe [H]

Synonym: lp_1621

Alternate gene names: 28378321

Gene position: 1476334-1476987 (Clockwise)

Preceding gene: 28378320

Following gene: 28378322

Centisome position: 44.63

GC content: 45.41

Gene sequence:

>654_bases
ATGATTAAAGTTGCCCCTTCAATTTTAAGTGCAGATTTTGCGAACCTTCAACGTGACGTTCAGATGGCTGAAAATGCCGG
TGCCGATGCGTTGCATATTGACGTGATGGATGGTCAGTTTGTCCCCAACTTGTCATTCGGAATGAGTACTGTGGCGGATT
TACGGCCAGTAACGTCATTAATGTTAGATTGTCATTTAATGATTATGGACCCAGAGCGGTTTGTTGGGCAGTTTGCAAAG
GCCGGTGCAGATTTGATTGGTGTGCACGTTGAAAGTACCCGTCACATTTATCACGCCTTACAATTAATCAAAGATGCTGG
TGTGAAAGCCGAAGTGGTCGTGAACCCCGGAACACCACTCAGCATGATTAGTGAATTATTGCCACTAGTGGATCAAGTTT
TGATTATGACCGTCAATCCTGGTTTTGGTGGTCAACATTTTCTGGACCAAATGGTTGCTAAAATTGCGGCGTTGAACGAA
TTGAAGCAACAACACGGTTATCGATTTGAGATTGAAGTTGATGGTGGAATCAACGACCAGACCGTCAAGGCGTGCTATGA
CGCTGGTGCTACGGTCGCTGTTGCTGGTTCGTATGTCTATGACAGTGCGGACCCTGCACAACGTATTCAAGATTTGAAGG
TGGCGACCAATTAA

Upstream 100 bases:

>100_bases
TGGGGAGCTGTTAGCGAGTCGCTATGATAATTATTTACAATTCTATGAAACCATTAAAAATAAAAAAGTAATCTATAATA
AGAAAAAGTGAGTGAGACTA

Downstream 100 bases:

>100_bases
TGGCAACCATCGTAAACTTACTGGTTGGCGGACCGACCGCTAATTATCCAGCAGATTTAACGACGATTCCAGGACCATGG
GTCGGCGCTGACCGTGGCGC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MIKVAPSILSADFANLQRDVQMAENAGADALHIDVMDGQFVPNLSFGMSTVADLRPVTSLMLDCHLMIMDPERFVGQFAK
AGADLIGVHVESTRHIYHALQLIKDAGVKAEVVVNPGTPLSMISELLPLVDQVLIMTVNPGFGGQHFLDQMVAKIAALNE
LKQQHGYRFEIEVDGGINDQTVKACYDAGATVAVAGSYVYDSADPAQRIQDLKVATN

Sequences:

>Translated_217_residues
MIKVAPSILSADFANLQRDVQMAENAGADALHIDVMDGQFVPNLSFGMSTVADLRPVTSLMLDCHLMIMDPERFVGQFAK
AGADLIGVHVESTRHIYHALQLIKDAGVKAEVVVNPGTPLSMISELLPLVDQVLIMTVNPGFGGQHFLDQMVAKIAALNE
LKQQHGYRFEIEVDGGINDQTVKACYDAGATVAVAGSYVYDSADPAQRIQDLKVATN
>Mature_217_residues
MIKVAPSILSADFANLQRDVQMAENAGADALHIDVMDGQFVPNLSFGMSTVADLRPVTSLMLDCHLMIMDPERFVGQFAK
AGADLIGVHVESTRHIYHALQLIKDAGVKAEVVVNPGTPLSMISELLPLVDQVLIMTVNPGFGGQHFLDQMVAKIAALNE
LKQQHGYRFEIEVDGGINDQTVKACYDAGATVAVAGSYVYDSADPAQRIQDLKVATN

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=213, Percent_Identity=38.4976525821596, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI219879828, Length=213, Percent_Identity=37.0892018779343, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI24307923, Length=167, Percent_Identity=33.5329341317365, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1789788, Length=211, Percent_Identity=42.1800947867299, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1790523, Length=213, Percent_Identity=34.7417840375587, Blast_Score=146, Evalue=9e-37,
Organism=Escherichia coli, GI1790754, Length=199, Percent_Identity=31.1557788944724, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=206, Percent_Identity=37.8640776699029, Blast_Score=136, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6322341, Length=223, Percent_Identity=43.0493273542601, Blast_Score=181, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=38.6792452830189, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23393; Mature: 23393

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVAPSILSADFANLQRDVQMAENAGADALHIDVMDGQFVPNLSFGMSTVADLRPVTSL
CCEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
MLDCHLMIMDPERFVGQFAKAGADLIGVHVESTRHIYHALQLIKDAGVKAEVVVNPGTPL
HHHHEEEEECHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCH
SMISELLPLVDQVLIMTVNPGFGGQHFLDQMVAKIAALNELKQQHGYRFEIEVDGGINDQ
HHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
TVKACYDAGATVAVAGSYVYDSADPAQRIQDLKVATN
HHHHHHCCCCEEEEECCEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIKVAPSILSADFANLQRDVQMAENAGADALHIDVMDGQFVPNLSFGMSTVADLRPVTSL
CCEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
MLDCHLMIMDPERFVGQFAKAGADLIGVHVESTRHIYHALQLIKDAGVKAEVVVNPGTPL
HHHHEEEEECHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCH
SMISELLPLVDQVLIMTVNPGFGGQHFLDQMVAKIAALNELKQQHGYRFEIEVDGGINDQ
HHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
TVKACYDAGATVAVAGSYVYDSADPAQRIQDLKVATN
HHHHHHCCCCEEEEECCEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]