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The map label for this gene is rsgA1

Identifier: 28378320

GI number: 28378320

Start: 1475428

End: 1476324

Strand: Direct

Name: rsgA1

Synonym: lp_1620

Alternate gene names: 28378320

Gene position: 1475428-1476324 (Clockwise)

Preceding gene: 28378319

Following gene: 28378321

Centisome position: 44.6

GC content: 46.71

Gene sequence:

>897_bases
TTGAAAATTGGACAAATTCGGCAATCGCTAAGCGGTTTTTATGACGTTTATGCTGATGGCCAAATGTATCGGACCCGTGC
ACGCGGGAATTTCCGGAAGCGGCGGATTACGCCACTTGTCGGCGACAATGTGGAGTTTGATGCGGCGACCCCACAAGAGG
GCTACGTGTTAAACATTCTTGATCGACAGACCCAGTTGGTACGGCCGCCAGTGGCTAATGTTGATTTAGGTATCGTGGTA
ACCGCTACAACGGAACAAGAATTTTCAACGAATTTATTGGATCGACAACTGGTAGCTTTGGCAGTGGCAGGTATTGAACC
ATTACTCTACTTTGCGAAGACTGATTTACTAACCGATGAGGTGTACCAACAACGATTAACATTAGCGGACGCTTATCGGC
AGATTGGTTACCAGGTCATCTGCGAACGAACCGCATTTTCACCGGCCGCCTTAGCCGCAGTTAAAACGGCTCTGGCTGGT
CATGTGGCGGTTGTCATGGGCCAAACTGGTGCTGGCAAGTCAACACTGCTAAATCATTTACAACCAGGGCTGGCGTTAGC
GACTGGTGAAATCTCGCAGGCGCTGAATCGTGGGAAACATACGACCCGTAAAGTCAGCTTGATTCCGATTGCGGATGGGT
TGGTTGCTGATACGCCGGGTTTCTCATCCTATGAAGTTTTCGATATTGCCGCTAACGAGTTGACCCATTATTTTCCAGAA
TTTGTGCGACTTAGCGTTGATTGCAAATACCGAGGCTGTGTGCATATTAACGAACCGCAATGTGCGGTTAAACAGGCATT
GGCAGCTGGGGAGCTGTTAGCGAGTCGCTATGATAATTATTTACAATTCTATGAAACCATTAAAAATAAAAAAGTAATCT
ATAATAAGAAAAAGTGA

Upstream 100 bases:

>100_bases
AAGTGCAACAAAATAAAGATAAGTCATGCGCAATGCATGACTTTTTTGGTACAATAGAGAAAAGTGGACCGTACCAAATA
ATATAAAAGGTGGTGCTAAT

Downstream 100 bases:

>100_bases
GTGAGACTAATGATTAAAGTTGCCCCTTCAATTTTAAGTGCAGATTTTGCGAACCTTCAACGTGACGTTCAGATGGCTGA
AAATGCCGGTGCCGATGCGT

Product: translation factor, GTPase (putative)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKIGQIRQSLSGFYDVYADGQMYRTRARGNFRKRRITPLVGDNVEFDAATPQEGYVLNILDRQTQLVRPPVANVDLGIVV
TATTEQEFSTNLLDRQLVALAVAGIEPLLYFAKTDLLTDEVYQQRLTLADAYRQIGYQVICERTAFSPAALAAVKTALAG
HVAVVMGQTGAGKSTLLNHLQPGLALATGEISQALNRGKHTTRKVSLIPIADGLVADTPGFSSYEVFDIAANELTHYFPE
FVRLSVDCKYRGCVHINEPQCAVKQALAAGELLASRYDNYLQFYETIKNKKVIYNKKK

Sequences:

>Translated_298_residues
MKIGQIRQSLSGFYDVYADGQMYRTRARGNFRKRRITPLVGDNVEFDAATPQEGYVLNILDRQTQLVRPPVANVDLGIVV
TATTEQEFSTNLLDRQLVALAVAGIEPLLYFAKTDLLTDEVYQQRLTLADAYRQIGYQVICERTAFSPAALAAVKTALAG
HVAVVMGQTGAGKSTLLNHLQPGLALATGEISQALNRGKHTTRKVSLIPIADGLVADTPGFSSYEVFDIAANELTHYFPE
FVRLSVDCKYRGCVHINEPQCAVKQALAAGELLASRYDNYLQFYETIKNKKVIYNKKK
>Mature_298_residues
MKIGQIRQSLSGFYDVYADGQMYRTRARGNFRKRRITPLVGDNVEFDAATPQEGYVLNILDRQTQLVRPPVANVDLGIVV
TATTEQEFSTNLLDRQLVALAVAGIEPLLYFAKTDLLTDEVYQQRLTLADAYRQIGYQVICERTAFSPAALAAVKTALAG
HVAVVMGQTGAGKSTLLNHLQPGLALATGEISQALNRGKHTTRKVSLIPIADGLVADTPGFSSYEVFDIAANELTHYFPE
FVRLSVDCKYRGCVHINEPQCAVKQALAAGELLASRYDNYLQFYETIKNKKVIYNKKK

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=295, Percent_Identity=32.5423728813559, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA1_LACPL (Q88WK9)

Other databases:

- EMBL:   AL935256
- RefSeq:   NP_785212.1
- ProteinModelPortal:   Q88WK9
- SMR:   Q88WK9
- GeneID:   1063713
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1620
- NMPDR:   fig|220668.1.peg.1346
- HOGENOM:   HBG652450
- OMA:   TRARGVF
- BioCyc:   LPLA220668:LP_1620-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 32953; Mature: 32953

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGQIRQSLSGFYDVYADGQMYRTRARGNFRKRRITPLVGDNVEFDAATPQEGYVLNIL
CCHHHHHHHHHHHHHHHCCCHHEEHHHCCCHHHHCCCCCCCCCEEECCCCCCCCCEEEEE
DRQTQLVRPPVANVDLGIVVTATTEQEFSTNLLDRQLVALAVAGIEPLLYFAKTDLLTDE
CCCHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYQQRLTLADAYRQIGYQVICERTAFSPAALAAVKTALAGHVAVVMGQTGAGKSTLLNHL
HHHHHHHHHHHHHHCCHHEEHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHC
QPGLALATGEISQALNRGKHTTRKVSLIPIADGLVADTPGFSSYEVFDIAANELTHYFPE
CCCCEEEHHHHHHHHHCCCCCCEEEEEEEECCCCEECCCCCCCEEEEEHHHHHHHHHHHH
FVRLSVDCKYRGCVHINEPQCAVKQALAAGELLASRYDNYLQFYETIKNKKVIYNKKK
HHEEEECEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MKIGQIRQSLSGFYDVYADGQMYRTRARGNFRKRRITPLVGDNVEFDAATPQEGYVLNIL
CCHHHHHHHHHHHHHHHCCCHHEEHHHCCCHHHHCCCCCCCCCEEECCCCCCCCCEEEEE
DRQTQLVRPPVANVDLGIVVTATTEQEFSTNLLDRQLVALAVAGIEPLLYFAKTDLLTDE
CCCHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYQQRLTLADAYRQIGYQVICERTAFSPAALAAVKTALAGHVAVVMGQTGAGKSTLLNHL
HHHHHHHHHHHHHHCCHHEEHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHC
QPGLALATGEISQALNRGKHTTRKVSLIPIADGLVADTPGFSSYEVFDIAANELTHYFPE
CCCCEEEHHHHHHHHHCCCCCCEEEEEEEECCCCEECCCCCCCEEEEEHHHHHHHHHHHH
FVRLSVDCKYRGCVHINEPQCAVKQALAAGELLASRYDNYLQFYETIKNKKVIYNKKK
HHEEEECEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566