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The map label for this gene is cobC [H]

Identifier: 28377791

GI number: 28377791

Start: 902437

End: 903105

Strand: Direct

Name: cobC [H]

Synonym: lp_0971

Alternate gene names: 28377791

Gene position: 902437-903105 (Clockwise)

Preceding gene: 28377790

Following gene: 28377800

Centisome position: 27.28

GC content: 49.18

Gene sequence:

>669_bases
ATGCAGATTTATTTCATTCGTCACGGTCGAACACAATATAACTTAGAACACCGATTTCAAGGTGGACGAGCAGATTCCCC
GCTGGTTGCTAGCGGAATCGATGGGGCAAAGGCCGCTGGTGATTACTTAAGAACCACCCAATTTTCAGCAGTATATAGTA
GTCCGCAGCAACGAGCGCTGGATACGGCGAAATACATTGTGGCTGCCAATCAGTGGCAACCGCCGATTCAAATCGACGAT
GGCTTGCGTGAGTTTGATTTTGGTGATTGGGACGGCAAACAGGAAGCGGAAGTACAGCCGCAGTCCTACGCCCAAGTTAT
TTTTACTAAACCCGCCGAATACCGACCGGAACTAGCTGGCGGTGGCGAAAGTTATGCGGATTTTGTCACCCGAACGACTT
CGACGCTACATCGTTTGATTGATCAAGTTGGGGTAGCTAGCACGCAACCACTATTAATCGTATCGCACGGCCTGGTGACG
ACGATGACTGTCAAGGCGTTAATGGGTGTCCCCGTAGCAGAATTACGAGCACCTTTTGTGGTCGATGGGCAAGTTATGAA
GACAGTCGGCCACGGAATCGTGGATAATGATAGCCTGACAGTGTTATCGACGACGGATAATCAGCATTTTGAACTGACGA
CTTGGAATGAAACCGGGTACTTGAAGTAA

Upstream 100 bases:

>100_bases
CACGGTATTTTTTTACGTCATTATGGCACTGAAGACTTTTCTATTGAGCATGACACAGTTAGAATTAAACTATTGAACGG
ATTAGGAAGGTGAACGTGCC

Downstream 100 bases:

>100_bases
ATGGCTGAGCCAAGTACAACGCCTTACTTTAGCTGTTAACTTGACTCTGATCGATAAAATTTTAAGTAGTTAGTAAAGGG
ACGCTTCTGGCATGGTTTGT

Product: alpha-ribazole-5'-phosphate phosphatase (putative)

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MQIYFIRHGRTQYNLEHRFQGGRADSPLVASGIDGAKAAGDYLRTTQFSAVYSSPQQRALDTAKYIVAANQWQPPIQIDD
GLREFDFGDWDGKQEAEVQPQSYAQVIFTKPAEYRPELAGGGESYADFVTRTTSTLHRLIDQVGVASTQPLLIVSHGLVT
TMTVKALMGVPVAELRAPFVVDGQVMKTVGHGIVDNDSLTVLSTTDNQHFELTTWNETGYLK

Sequences:

>Translated_222_residues
MQIYFIRHGRTQYNLEHRFQGGRADSPLVASGIDGAKAAGDYLRTTQFSAVYSSPQQRALDTAKYIVAANQWQPPIQIDD
GLREFDFGDWDGKQEAEVQPQSYAQVIFTKPAEYRPELAGGGESYADFVTRTTSTLHRLIDQVGVASTQPLLIVSHGLVT
TMTVKALMGVPVAELRAPFVVDGQVMKTVGHGIVDNDSLTVLSTTDNQHFELTTWNETGYLK
>Mature_222_residues
MQIYFIRHGRTQYNLEHRFQGGRADSPLVASGIDGAKAAGDYLRTTQFSAVYSSPQQRALDTAKYIVAANQWQPPIQIDD
GLREFDFGDWDGKQEAEVQPQSYAQVIFTKPAEYRPELAGGGESYADFVTRTTSTLHRLIDQVGVASTQPLLIVSHGLVT
TMTVKALMGVPVAELRAPFVVDGQVMKTVGHGIVDNDSLTVLSTTDNQHFELTTWNETGYLK

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=182, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 24511; Mature: 24511

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIYFIRHGRTQYNLEHRFQGGRADSPLVASGIDGAKAAGDYLRTTQFSAVYSSPQQRAL
CEEEEEECCCEEECHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
DTAKYIVAANQWQPPIQIDDGLREFDFGDWDGKQEAEVQPQSYAQVIFTKPAEYRPELAG
HHHHEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCC
GGESYADFVTRTTSTLHRLIDQVGVASTQPLLIVSHGLVTTMTVKALMGVPVAELRAPFV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHCCCEE
VDGQVMKTVGHGIVDNDSLTVLSTTDNQHFELTTWNETGYLK
ECCHHHHHHCCCEECCCCEEEEEECCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MQIYFIRHGRTQYNLEHRFQGGRADSPLVASGIDGAKAAGDYLRTTQFSAVYSSPQQRAL
CEEEEEECCCEEECHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
DTAKYIVAANQWQPPIQIDDGLREFDFGDWDGKQEAEVQPQSYAQVIFTKPAEYRPELAG
HHHHEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCC
GGESYADFVTRTTSTLHRLIDQVGVASTQPLLIVSHGLVTTMTVKALMGVPVAELRAPFV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHCCCEE
VDGQVMKTVGHGIVDNDSLTVLSTTDNQHFELTTWNETGYLK
ECCHHHHHHCCCEECCCCEEEEEECCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]