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The map label for this gene is pbg2 [H]

Identifier: 28377738

GI number: 28377738

Start: 835698

End: 837200

Strand: Direct

Name: pbg2 [H]

Synonym: lp_0906

Alternate gene names: 28377738

Gene position: 835698-837200 (Clockwise)

Preceding gene: 28377737

Following gene: 28377740

Centisome position: 25.26

GC content: 41.18

Gene sequence:

>1503_bases
ATGGATGTTTACAAAACGAGTCCTAACTTTATGTGGGGCGTAGCAACTGCTGCTAATCAAGTAGAAGGCGCATGGAACGA
GGACGGTAAAGGCATGTCTATTGCAGATTGCCTGCGTTATCGGCCGCAAATTGATAGTAGTGACTATCAAGCGGTGAACC
AAATGGATAGTGCTGAAATTGAAAACGCCTTAAATGATGAATCGACTAAAGGTTGGGCAAAACGGCATGGTGTGGATTTT
TATCATCATTATCGAGAAGATATTAAACAGTTGGCAGAGACAGGAATCAATACCTATCGATTCTCGATAAGTTGGGCCCG
TATTTTTCCAAATGGTGACGATAAGTGTCCTAATCAAGCGGGGTTAGACTTCTACCTGTCACTAGTTAAAGAATTGGCAA
AGTACCAAATTACACCAGTGGTGACGCTATCCCACTACGAAATGCCGTTAAACTTAGTGCTAAATTATGATGCTTGGTAT
GATCGACGAGTGGCAGACTTTTTTGGGCGTTATGCGCGAACCGTCATTGATTATTTACATGATTATGTCAAGTACTGGAT
TCCGATTAATGAAATTGACAGTATTATTAGGCACCCATTCTCATCAGCTGGATTAGTCGCAGATCGTTTTGCTAGTCATG
ATTTTAAAACGGTTATTTATCAAGCAATGCATCATCAGTTTGTGGCAGCGGCACAGGTTGTCAAGTATTGTCATCGTCAC
TATCCACAGATGCAAGTTGGTAGCATGATTACTAGAACGATGGTTTATCCATATAATAGTGATCCCAATAATGTGCTTGC
AGCAACGCAAACGATGCGTGAGGTGTATGCATTTAGCGATATTCAAGTGCGTGGAGAATACCCTGAATTCTTGTTAACTA
AGCTGAAAAAAGCACATATTACGATTGAATTTCAGGAGGGTGATCAGGAAGTACTACGTGAGAATACGGCCGATTTTGTG
GCCTTTAGTTACTACTCCTCAATTTGCACGGCTAGTAATGTGGAAGGCCTGCGGGTGACCAAGGCTAATCGAACCGTTGG
CGTTTATAATCGGTACTTGCCTGAGAGTGAGTGGGGGTGGCAGATTGATCCAGTTGGATTGAGACTATCTTTAATCGATT
TGTTCGATCGCTACCAAAAGCCGTTATTCATTGTCGAAAATGGCCTAGGTGCTGTGGATGAGTTGAGCAGTGATCTTCGT
GTTCATGACATATATCGAATCAGTTACTTGCGCCAGCACATTCGGCAGATGTTAATAGCCATTGCGAATGATGGTGTGGA
CTTAATGGGGTACTGTATGTGGGGAACCACCGATATGATATCTGCGTCGTCAAACCAAATGTCAAAGCGGTATGGTTTAA
TCTATGTTGACTTAGATGATAATGGTGATGGCTCATATAATCGATATTTAAAGGACAGTTATTTCTGGTATCAAGAATTA
CTAAGCTATAAGAATCAAATTCCAGCAATTTTTTTAGATGAAAATAGTATAGTCATTCAATGA

Upstream 100 bases:

>100_bases
ATACAAAGGACTTTTTAGAGGTTCTACCAGTACCAGAATCGAACGAATCTGTAACCGCAGATAATAATTTATTAATGTTA
GCGTAAGTGAGGTAGGATTG

Downstream 100 bases:

>100_bases
GCCTAATAAAAAAAGGGCGCAATTTAATTTGCGCCCTTTTTTACTAATTCTATTTATAAGAGAACCGTTGTTGTCGCCAG
GTCTTAATCAGCGCAACCAC

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MDVYKTSPNFMWGVATAANQVEGAWNEDGKGMSIADCLRYRPQIDSSDYQAVNQMDSAEIENALNDESTKGWAKRHGVDF
YHHYREDIKQLAETGINTYRFSISWARIFPNGDDKCPNQAGLDFYLSLVKELAKYQITPVVTLSHYEMPLNLVLNYDAWY
DRRVADFFGRYARTVIDYLHDYVKYWIPINEIDSIIRHPFSSAGLVADRFASHDFKTVIYQAMHHQFVAAAQVVKYCHRH
YPQMQVGSMITRTMVYPYNSDPNNVLAATQTMREVYAFSDIQVRGEYPEFLLTKLKKAHITIEFQEGDQEVLRENTADFV
AFSYYSSICTASNVEGLRVTKANRTVGVYNRYLPESEWGWQIDPVGLRLSLIDLFDRYQKPLFIVENGLGAVDELSSDLR
VHDIYRISYLRQHIRQMLIAIANDGVDLMGYCMWGTTDMISASSNQMSKRYGLIYVDLDDNGDGSYNRYLKDSYFWYQEL
LSYKNQIPAIFLDENSIVIQ

Sequences:

>Translated_500_residues
MDVYKTSPNFMWGVATAANQVEGAWNEDGKGMSIADCLRYRPQIDSSDYQAVNQMDSAEIENALNDESTKGWAKRHGVDF
YHHYREDIKQLAETGINTYRFSISWARIFPNGDDKCPNQAGLDFYLSLVKELAKYQITPVVTLSHYEMPLNLVLNYDAWY
DRRVADFFGRYARTVIDYLHDYVKYWIPINEIDSIIRHPFSSAGLVADRFASHDFKTVIYQAMHHQFVAAAQVVKYCHRH
YPQMQVGSMITRTMVYPYNSDPNNVLAATQTMREVYAFSDIQVRGEYPEFLLTKLKKAHITIEFQEGDQEVLRENTADFV
AFSYYSSICTASNVEGLRVTKANRTVGVYNRYLPESEWGWQIDPVGLRLSLIDLFDRYQKPLFIVENGLGAVDELSSDLR
VHDIYRISYLRQHIRQMLIAIANDGVDLMGYCMWGTTDMISASSNQMSKRYGLIYVDLDDNGDGSYNRYLKDSYFWYQEL
LSYKNQIPAIFLDENSIVIQ
>Mature_500_residues
MDVYKTSPNFMWGVATAANQVEGAWNEDGKGMSIADCLRYRPQIDSSDYQAVNQMDSAEIENALNDESTKGWAKRHGVDF
YHHYREDIKQLAETGINTYRFSISWARIFPNGDDKCPNQAGLDFYLSLVKELAKYQITPVVTLSHYEMPLNLVLNYDAWY
DRRVADFFGRYARTVIDYLHDYVKYWIPINEIDSIIRHPFSSAGLVADRFASHDFKTVIYQAMHHQFVAAAQVVKYCHRH
YPQMQVGSMITRTMVYPYNSDPNNVLAATQTMREVYAFSDIQVRGEYPEFLLTKLKKAHITIEFQEGDQEVLRENTADFV
AFSYYSSICTASNVEGLRVTKANRTVGVYNRYLPESEWGWQIDPVGLRLSLIDLFDRYQKPLFIVENGLGAVDELSSDLR
VHDIYRISYLRQHIRQMLIAIANDGVDLMGYCMWGTTDMISASSNQMSKRYGLIYVDLDDNGDGSYNRYLKDSYFWYQEL
LSYKNQIPAIFLDENSIVIQ

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=476, Percent_Identity=30.4621848739496, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI13273313, Length=474, Percent_Identity=28.2700421940928, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24497614, Length=494, Percent_Identity=28.5425101214575, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI110681710, Length=499, Percent_Identity=27.8557114228457, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI28376633, Length=487, Percent_Identity=27.5154004106776, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=43.7759336099585, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI2367270, Length=477, Percent_Identity=47.1698113207547, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI2367174, Length=478, Percent_Identity=44.5606694560669, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17552856, Length=494, Percent_Identity=26.9230769230769, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17539390, Length=497, Percent_Identity=26.1569416498994, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21356577, Length=482, Percent_Identity=27.5933609958506, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 57887; Mature: 57887

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVYKTSPNFMWGVATAANQVEGAWNEDGKGMSIADCLRYRPQIDSSDYQAVNQMDSAEI
CCCEECCCCEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHH
ENALNDESTKGWAKRHGVDFYHHYREDIKQLAETGINTYRFSISWARIFPNGDDKCPNQA
HHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCC
GLDFYLSLVKELAKYQITPVVTLSHYEMPLNLVLNYDAWYDRRVADFFGRYARTVIDYLH
CHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
DYVKYWIPINEIDSIIRHPFSSAGLVADRFASHDFKTVIYQAMHHQFVAAAQVVKYCHRH
HHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPQMQVGSMITRTMVYPYNSDPNNVLAATQTMREVYAFSDIQVRGEYPEFLLTKLKKAHI
CCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHEEE
TIEFQEGDQEVLRENTADFVAFSYYSSICTASNVEGLRVTKANRTVGVYNRYLPESEWGW
EEEEECCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHCCCCCCCCE
QIDPVGLRLSLIDLFDRYQKPLFIVENGLGAVDELSSDLRVHDIYRISYLRQHIRQMLIA
EECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IANDGVDLMGYCMWGTTDMISASSNQMSKRYGLIYVDLDDNGDGSYNRYLKDSYFWYQEL
HHCCCCCEEEEEECCCHHHHCCCCHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LSYKNQIPAIFLDENSIVIQ
HHHHHCCCEEEECCCCEEEC
>Mature Secondary Structure
MDVYKTSPNFMWGVATAANQVEGAWNEDGKGMSIADCLRYRPQIDSSDYQAVNQMDSAEI
CCCEECCCCEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHH
ENALNDESTKGWAKRHGVDFYHHYREDIKQLAETGINTYRFSISWARIFPNGDDKCPNQA
HHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCC
GLDFYLSLVKELAKYQITPVVTLSHYEMPLNLVLNYDAWYDRRVADFFGRYARTVIDYLH
CHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
DYVKYWIPINEIDSIIRHPFSSAGLVADRFASHDFKTVIYQAMHHQFVAAAQVVKYCHRH
HHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPQMQVGSMITRTMVYPYNSDPNNVLAATQTMREVYAFSDIQVRGEYPEFLLTKLKKAHI
CCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHEEE
TIEFQEGDQEVLRENTADFVAFSYYSSICTASNVEGLRVTKANRTVGVYNRYLPESEWGW
EEEEECCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHCCCCCCCCE
QIDPVGLRLSLIDLFDRYQKPLFIVENGLGAVDELSSDLRVHDIYRISYLRQHIRQMLIA
EECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IANDGVDLMGYCMWGTTDMISASSNQMSKRYGLIYVDLDDNGDGSYNRYLKDSYFWYQEL
HHCCCCCEEEEEECCCHHHHCCCCHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LSYKNQIPAIFLDENSIVIQ
HHHHHCCCEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]