Click here to switch to the map view.

The map label for this gene is tagH

Identifier: 28377262

GI number: 28377262

Start: 314266

End: 315357

Strand: Direct

Name: tagH

Synonym: lp_0344

Alternate gene names: 28377262

Gene position: 314266-315357 (Clockwise)

Preceding gene: 28377261

Following gene: 28377263

Centisome position: 9.5

GC content: 41.39

Gene sequence:

>1092_bases
ATGGAAAATCAATATAAGGTTGAATTGCATAATGTCACTAAAGAATATGATTTATATCGTAGTAACAACGATAAGTTAAA
ACACTTTTTTAACATTGGTAATGTTGATGTCCCGCGGTTTTGGTCGCTAAAAGGGGTCAGCTTAAACGTTAAACCAGGTG
AAGCGTTGGGTATTATCGGAATCAACGGTTCTGGTAAGTCAACGATTTCGAATATCATTTCGGGAATCATTCCTCAAACG
ACTGGGACAGTGGATGTGCACGGTGATACGTCCATTATTTCAATCGGAGCCGGCTTAAAGTGGAATTTGACCGGTGATGA
AAACATTCGGTTGAAAGGACTCATGCAAGGGTTGAGTATTAAAGAGATCCAAGCGGTTCGTGATGATATTGTTGATTTCG
CGGATATTGGTGATTTTATTGGTCAACCAGTTAAGGACTATTCGACCGGGATGCGGTCACGATTGGGATTTGCGATTGCG
GTGCATATCAATCCCGACATCATGATTATTGATGAAGCACTATCGGTTGGTGATGACACCTTCTATCAAAAATGTGTGGA
TAAGATTATGGAATTCAAGAAGCAAGGGAAGACTATTATCTTTGTCAGCCATAATTTACGGCAAGTAGAATTGCTTTGTG
ACCGGGTCGCTTGGATGCACTTTGGGGATCTTTTAGAAGTCGGCGAGACCAAGGAAACTGTTGATCATTACCGGAAATTT
TCTAAGGATTTCAAAGCGCAAACGGCGGCTTATCGTAAGAAGTATCAGGTCGGTAAGAAGAAGGAACAAGCGGACTTTGA
CATTGTCGCTTATGAACGACAATTAGTCGAAGAAAAGGCTAAGGATAGCGATAAGAGTAAGCAGGCAGTTAGCCGTCAAG
TTCATCGGACGCTATACAAGCAAATCTTGCCAGAAAAGATGACGATTGCCACCAAGCTCGTCATGTTAGTGGCAATTGTC
CTGTTCGTCTTCTTTGCGTTAGTGAATGTTTCAGGTCACTCGGTTACTTCGGCGATTGAGAATCCGACAGTACTGTTACA
TCCAGTCAATCATTATATTAAAAGTCAGTCAGTCTTATTCAATAGTAAGTGA

Upstream 100 bases:

>100_bases
TGTCTTTTGGCTCTTCAATCTCGTTGTGATTCTGACTGGAACGTATCTCTATAACAAGTTCCGTTCGAACTTTGTGGATT
TGATTTAGGAGGCGGAACTG

Downstream 100 bases:

>100_bases
CGGCGGCTGGTTAGTGGTTGCATTAAATTAACATTAATATCGATGGGTGATTGCGATGGCAATCACCCATTTTTTGTGTG
CATTCAAGACGGCTTTGGTT

Product: teichoic acid ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MENQYKVELHNVTKEYDLYRSNNDKLKHFFNIGNVDVPRFWSLKGVSLNVKPGEALGIIGINGSGKSTISNIISGIIPQT
TGTVDVHGDTSIISIGAGLKWNLTGDENIRLKGLMQGLSIKEIQAVRDDIVDFADIGDFIGQPVKDYSTGMRSRLGFAIA
VHINPDIMIIDEALSVGDDTFYQKCVDKIMEFKKQGKTIIFVSHNLRQVELLCDRVAWMHFGDLLEVGETKETVDHYRKF
SKDFKAQTAAYRKKYQVGKKKEQADFDIVAYERQLVEEKAKDSDKSKQAVSRQVHRTLYKQILPEKMTIATKLVMLVAIV
LFVFFALVNVSGHSVTSAIENPTVLLHPVNHYIKSQSVLFNSK

Sequences:

>Translated_363_residues
MENQYKVELHNVTKEYDLYRSNNDKLKHFFNIGNVDVPRFWSLKGVSLNVKPGEALGIIGINGSGKSTISNIISGIIPQT
TGTVDVHGDTSIISIGAGLKWNLTGDENIRLKGLMQGLSIKEIQAVRDDIVDFADIGDFIGQPVKDYSTGMRSRLGFAIA
VHINPDIMIIDEALSVGDDTFYQKCVDKIMEFKKQGKTIIFVSHNLRQVELLCDRVAWMHFGDLLEVGETKETVDHYRKF
SKDFKAQTAAYRKKYQVGKKKEQADFDIVAYERQLVEEKAKDSDKSKQAVSRQVHRTLYKQILPEKMTIATKLVMLVAIV
LFVFFALVNVSGHSVTSAIENPTVLLHPVNHYIKSQSVLFNSK
>Mature_363_residues
MENQYKVELHNVTKEYDLYRSNNDKLKHFFNIGNVDVPRFWSLKGVSLNVKPGEALGIIGINGSGKSTISNIISGIIPQT
TGTVDVHGDTSIISIGAGLKWNLTGDENIRLKGLMQGLSIKEIQAVRDDIVDFADIGDFIGQPVKDYSTGMRSRLGFAIA
VHINPDIMIIDEALSVGDDTFYQKCVDKIMEFKKQGKTIIFVSHNLRQVELLCDRVAWMHFGDLLEVGETKETVDHYRKF
SKDFKAQTAAYRKKYQVGKKKEQADFDIVAYERQLVEEKAKDSDKSKQAVSRQVHRTLYKQILPEKMTIATKLVMLVAIV
LFVFFALVNVSGHSVTSAIENPTVLLHPVNHYIKSQSVLFNSK

Specific function: Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI27262624, Length=216, Percent_Identity=31.9444444444444, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27262626, Length=216, Percent_Identity=31.9444444444444, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI153792144, Length=220, Percent_Identity=28.1818181818182, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27477115, Length=212, Percent_Identity=29.2452830188679, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI27436953, Length=209, Percent_Identity=28.7081339712919, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI6005701, Length=211, Percent_Identity=28.9099526066351, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI45446740, Length=211, Percent_Identity=24.6445497630332, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI47078218, Length=211, Percent_Identity=24.6445497630332, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI31657092, Length=212, Percent_Identity=26.8867924528302, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI21536376, Length=202, Percent_Identity=27.7227722772277, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI105990541, Length=205, Percent_Identity=25.3658536585366, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI150417984, Length=197, Percent_Identity=30.4568527918782, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI116734710, Length=221, Percent_Identity=26.6968325791855, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI89111135, Length=221, Percent_Identity=28.0542986425339, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI30795238, Length=203, Percent_Identity=26.6009852216749, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI27881501, Length=203, Percent_Identity=26.6009852216749, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI21729873, Length=279, Percent_Identity=25.089605734767, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI15149474, Length=279, Percent_Identity=25.089605734767, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI21729876, Length=279, Percent_Identity=25.089605734767, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789032, Length=241, Percent_Identity=28.6307053941909, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994943, Length=212, Percent_Identity=27.8301886792453, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081709, Length=235, Percent_Identity=25.1063829787234, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786319, Length=197, Percent_Identity=26.3959390862944, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081791, Length=294, Percent_Identity=22.4489795918367, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786398, Length=214, Percent_Identity=25.7009345794392, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081782, Length=199, Percent_Identity=25.6281407035176, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787029, Length=205, Percent_Identity=24.390243902439, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789672, Length=216, Percent_Identity=23.6111111111111, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789751, Length=164, Percent_Identity=26.219512195122, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790190, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787105, Length=241, Percent_Identity=25.3112033195021, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=229, Percent_Identity=25.3275109170306, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17510237, Length=210, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146777, Length=224, Percent_Identity=28.125, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71983523, Length=280, Percent_Identity=24.6428571428571, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71983516, Length=280, Percent_Identity=24.6428571428571, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983510, Length=280, Percent_Identity=24.6428571428571, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565586, Length=211, Percent_Identity=23.696682464455, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=216, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=216, Percent_Identity=28.7037037037037, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=216, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193202878, Length=202, Percent_Identity=24.7524752475248, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=216, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24643674, Length=213, Percent_Identity=25.8215962441315, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221512771, Length=236, Percent_Identity=26.271186440678, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62484234, Length=216, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007184, Length=186, Percent_Identity=25.2688172043011, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221500365, Length=186, Percent_Identity=25.2688172043011, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648314, Length=192, Percent_Identity=21.3541666666667, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161077321, Length=246, Percent_Identity=29.6747967479675, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550390, Length=311, Percent_Identity=24.1157556270096, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAGH_LACPL (Q88ZH4)

Other databases:

- EMBL:   AL935252
- RefSeq:   NP_784154.1
- ProteinModelPortal:   Q88ZH4
- SMR:   Q88ZH4
- GeneID:   1062178
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0344
- NMPDR:   fig|220668.1.peg.288
- HOGENOM:   HBG758042
- OMA:   EMGEAKE
- ProtClustDB:   CLSK581077
- BioCyc:   LPLA220668:LP_0344-MONOMER
- BRENDA:   3.6.3.40
- HAMAP:   MF_01715
- InterPro:   IPR003439
- InterPro:   IPR015860
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.40

Molecular weight: Translated: 40842; Mature: 40842

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51251 TAGH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQYKVELHNVTKEYDLYRSNNDKLKHFFNIGNVDVPRFWSLKGVSLNVKPGEALGIIG
CCCCEEEEEECCHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEECCCEEECCCCCEEEEEE
INGSGKSTISNIISGIIPQTTGTVDVHGDTSIISIGAGLKWNLTGDENIRLKGLMQGLSI
ECCCCHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCEEEECCCCCCEEHHHHHCCCCH
KEIQAVRDDIVDFADIGDFIGQPVKDYSTGMRSRLGFAIAVHINPDIMIIDEALSVGDDT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEECCCEEEEECHHHCCCHH
FYQKCVDKIMEFKKQGKTIIFVSHNLRQVELLCDRVAWMHFGDLLEVGETKETVDHYRKF
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SKDFKAQTAAYRKKYQVGKKKEQADFDIVAYERQLVEEKAKDSDKSKQAVSRQVHRTLYK
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QILPEKMTIATKLVMLVAIVLFVFFALVNVSGHSVTSAIENPTVLLHPVNHYIKSQSVLF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEECHHHHHCCCCEEE
NSK
CCC
>Mature Secondary Structure
MENQYKVELHNVTKEYDLYRSNNDKLKHFFNIGNVDVPRFWSLKGVSLNVKPGEALGIIG
CCCCEEEEEECCHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEECCCEEECCCCCEEEEEE
INGSGKSTISNIISGIIPQTTGTVDVHGDTSIISIGAGLKWNLTGDENIRLKGLMQGLSI
ECCCCHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCEEEECCCCCCEEHHHHHCCCCH
KEIQAVRDDIVDFADIGDFIGQPVKDYSTGMRSRLGFAIAVHINPDIMIIDEALSVGDDT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEECCCEEEEECHHHCCCHH
FYQKCVDKIMEFKKQGKTIIFVSHNLRQVELLCDRVAWMHFGDLLEVGETKETVDHYRKF
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SKDFKAQTAAYRKKYQVGKKKEQADFDIVAYERQLVEEKAKDSDKSKQAVSRQVHRTLYK
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QILPEKMTIATKLVMLVAIVLFVFFALVNVSGHSVTSAIENPTVLLHPVNHYIKSQSVLF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEECHHHHHCCCCEEE
NSK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12566566