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The map label for this gene is treA [H]

Identifier: 28377189

GI number: 28377189

Start: 236050

End: 237693

Strand: Direct

Name: treA [H]

Synonym: lp_0263

Alternate gene names: 28377189

Gene position: 236050-237693 (Clockwise)

Preceding gene: 28377188

Following gene: 28377190

Centisome position: 7.14

GC content: 46.05

Gene sequence:

>1644_bases
ATGAAATTATCAGAACAAGTGATTTATCAGATTTATCCGAAGTCGTTTTACGACAGCAATGGCGATGGCGTCGGTGATTT
ACGAGGTGTTATTGAAAAGATCGACTACCTCAAAAAGTTGAATATTGACATGATTTGGTTTAATCCGTTTTTTGTCTCAC
CACAAAATGATAACGGTTACGATATTGCAGATTACTACCATATTGACCCCATGTTTGGCACGATGGCTGATTTTGAAGAA
CTCGTTGCAAAGCTGAAGGCAAATGGTATCGGGGTCATGTTGGATATGGTTCTTAATCATACTTCAACTGAACACGAGTG
GTTTCAAAAGGCTTTGGCGGGTGATGAGAAGTATCAGAAGTTTTACTATCTCCGTCCTCCCAAGGCTGATGGTAGTCTAC
CGACCAATTGGGAATCTAAATTTGGTGGTCCGGCCTGGGCGCCGTTTGGTGATACTGGTTTGTACTATTTACATTTATAT
GATCCGACTCAGGCCGATTTGGATTGGCATAATCCGGCCGTACGACAAGCGTGTGCCGCCGTTGTCAATTTCTGGCGGCA
AAAGGGCGTGCAGGGTTTTCGTTTCGATGTCATCAACGTTACCGGTAAAGCTGAGAAGTTGGTGGACGCACCTAAGGGGG
TCCCTAGCAAGACGTTGTATACTGACACCCCCGTTGTTCATGATTATTTAAAGGAATTGAACGCGGCAAGCTTCGGCCAG
GATGTAAATAGCGTCACAGTGGGGGAGATGTCTTCAACAACCGTTGCAAACAGTGTTGGTTATACTAATCCGGCTAATCA
CGAACTCTCAATGGTCTTTAATTTCCATCATTTGAAGACGGATTATGTTGATGGCCGGAAGTGGTCCCGAATGGCCTTCG
ACTTCCCACGATTGAAGCAATTATTAGATAGTTGGGCCAGTGGAATGGCAGCTGGTGGTGGCTGGCAGGCTTTGTTTTGG
AATAATCATGATCAGCCACGAGCGCTGAATCGCTTTGGTGACGCCGGTCGTTATCGTGTCAAGTCCGCTGAAATGCTGGC
GACGGTCATTCACCTCTTGCGTGGAACACCGTTTATCTATATGGGTGAGGAACTCGGCATGACTGATCCGGACTATGACA
ATATGGCTGATTACGTGGACATTGAGGCATTAAATGCTTATCGGGCTTTAATTCGTAGTGGGTACAGTCATCACGATGCG
TTTACGATCGTTAAGACCAAGGCGCGCGATAACTCGCGGACGCCGATGCAATGGGATGATAGTGCCAAGGCTGGTTTCAC
TACTGGTAAACCGTGGTTGACACCGACTAATCAGGCGACGATTAACGTGGCCCATGAATTGGCTAGTGGCGAGATTTTTG
ACTATTATCAACGGCTCATTAAGCTAAGAAAAACGATGCCGATCGTCGCGGATGGTGGCTATCAATCGTGGCGCTTAGAT
GATCCGCAAGTCTTCGGCTATTGGCGGACATATCGCCAACAAAAGTTATTAGTGCTTAATAATTTTTATGGTCAGTCAAC
AACGGTGACACTTCCGGAAGAAATGGTCGGTGCACAGGTGTTACTTTCCAATTATCAAGATGTTAATGTCACAGCACAAT
TGACGATGCAACCCTATCAAGCGGTTGCGCTGTTGTTAGGTTAA

Upstream 100 bases:

>100_bases
GTTCCAGTATACGGAATCACGACACCGGGCGGACCGCTTTAGTTTCCGCGATTTTGCTCGGCGAACTAAGAAATAAGATG
TGGCATGAGAGGGATAGCGC

Downstream 100 bases:

>100_bases
GAATGGAGGAATGGGTATGGCAAAGGCACAAACAGTAACAATTTTGTCGCCGGTCAATGGGGACGTTATTGCGTTAAATA
AGGTTAAAGACCCGGTCTTT

Product: alpha, alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKLSEQVIYQIYPKSFYDSNGDGVGDLRGVIEKIDYLKKLNIDMIWFNPFFVSPQNDNGYDIADYYHIDPMFGTMADFEE
LVAKLKANGIGVMLDMVLNHTSTEHEWFQKALAGDEKYQKFYYLRPPKADGSLPTNWESKFGGPAWAPFGDTGLYYLHLY
DPTQADLDWHNPAVRQACAAVVNFWRQKGVQGFRFDVINVTGKAEKLVDAPKGVPSKTLYTDTPVVHDYLKELNAASFGQ
DVNSVTVGEMSSTTVANSVGYTNPANHELSMVFNFHHLKTDYVDGRKWSRMAFDFPRLKQLLDSWASGMAAGGGWQALFW
NNHDQPRALNRFGDAGRYRVKSAEMLATVIHLLRGTPFIYMGEELGMTDPDYDNMADYVDIEALNAYRALIRSGYSHHDA
FTIVKTKARDNSRTPMQWDDSAKAGFTTGKPWLTPTNQATINVAHELASGEIFDYYQRLIKLRKTMPIVADGGYQSWRLD
DPQVFGYWRTYRQQKLLVLNNFYGQSTTVTLPEEMVGAQVLLSNYQDVNVTAQLTMQPYQAVALLLG

Sequences:

>Translated_547_residues
MKLSEQVIYQIYPKSFYDSNGDGVGDLRGVIEKIDYLKKLNIDMIWFNPFFVSPQNDNGYDIADYYHIDPMFGTMADFEE
LVAKLKANGIGVMLDMVLNHTSTEHEWFQKALAGDEKYQKFYYLRPPKADGSLPTNWESKFGGPAWAPFGDTGLYYLHLY
DPTQADLDWHNPAVRQACAAVVNFWRQKGVQGFRFDVINVTGKAEKLVDAPKGVPSKTLYTDTPVVHDYLKELNAASFGQ
DVNSVTVGEMSSTTVANSVGYTNPANHELSMVFNFHHLKTDYVDGRKWSRMAFDFPRLKQLLDSWASGMAAGGGWQALFW
NNHDQPRALNRFGDAGRYRVKSAEMLATVIHLLRGTPFIYMGEELGMTDPDYDNMADYVDIEALNAYRALIRSGYSHHDA
FTIVKTKARDNSRTPMQWDDSAKAGFTTGKPWLTPTNQATINVAHELASGEIFDYYQRLIKLRKTMPIVADGGYQSWRLD
DPQVFGYWRTYRQQKLLVLNNFYGQSTTVTLPEEMVGAQVLLSNYQDVNVTAQLTMQPYQAVALLLG
>Mature_547_residues
MKLSEQVIYQIYPKSFYDSNGDGVGDLRGVIEKIDYLKKLNIDMIWFNPFFVSPQNDNGYDIADYYHIDPMFGTMADFEE
LVAKLKANGIGVMLDMVLNHTSTEHEWFQKALAGDEKYQKFYYLRPPKADGSLPTNWESKFGGPAWAPFGDTGLYYLHLY
DPTQADLDWHNPAVRQACAAVVNFWRQKGVQGFRFDVINVTGKAEKLVDAPKGVPSKTLYTDTPVVHDYLKELNAASFGQ
DVNSVTVGEMSSTTVANSVGYTNPANHELSMVFNFHHLKTDYVDGRKWSRMAFDFPRLKQLLDSWASGMAAGGGWQALFW
NNHDQPRALNRFGDAGRYRVKSAEMLATVIHLLRGTPFIYMGEELGMTDPDYDNMADYVDIEALNAYRALIRSGYSHHDA
FTIVKTKARDNSRTPMQWDDSAKAGFTTGKPWLTPTNQATINVAHELASGEIFDYYQRLIKLRKTMPIVADGGYQSWRLD
DPQVFGYWRTYRQQKLLVLNNFYGQSTTVTLPEEMVGAQVLLSNYQDVNVTAQLTMQPYQAVALLLG

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=542, Percent_Identity=27.859778597786, Blast_Score=192, Evalue=6e-49,
Organism=Escherichia coli, GI1790687, Length=542, Percent_Identity=45.9409594095941, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1786604, Length=186, Percent_Identity=29.0322580645161, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32565753, Length=197, Percent_Identity=27.9187817258883, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25147709, Length=500, Percent_Identity=24, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322245, Length=572, Percent_Identity=32.8671328671329, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321731, Length=573, Percent_Identity=33.3333333333333, Blast_Score=299, Evalue=9e-82,
Organism=Saccharomyces cerevisiae, GI6319776, Length=573, Percent_Identity=33.3333333333333, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6321726, Length=569, Percent_Identity=32.8646748681898, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6324416, Length=569, Percent_Identity=33.2161687170475, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6322241, Length=569, Percent_Identity=33.0404217926186, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6322021, Length=569, Percent_Identity=33.0404217926186, Blast_Score=288, Evalue=2e-78,
Organism=Drosophila melanogaster, GI221330053, Length=489, Percent_Identity=34.7648261758691, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24586591, Length=493, Percent_Identity=34.4827586206897, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI45549022, Length=582, Percent_Identity=32.1305841924399, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24583745, Length=544, Percent_Identity=31.6176470588235, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24583749, Length=559, Percent_Identity=32.737030411449, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24583747, Length=559, Percent_Identity=32.737030411449, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24586589, Length=484, Percent_Identity=34.9173553719008, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24586593, Length=532, Percent_Identity=32.8947368421053, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24586597, Length=538, Percent_Identity=30.8550185873606, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24586599, Length=539, Percent_Identity=30.9833024118738, Blast_Score=215, Evalue=6e-56,
Organism=Drosophila melanogaster, GI24586587, Length=576, Percent_Identity=30.0347222222222, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281360393, Length=483, Percent_Identity=30.2277432712215, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 62004; Mature: 62004

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSEQVIYQIYPKSFYDSNGDGVGDLRGVIEKIDYLKKLNIDMIWFNPFFVSPQNDNGY
CCCHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCC
DIADYYHIDPMFGTMADFEELVAKLKANGIGVMLDMVLNHTSTEHEWFQKALAGDEKYQK
EEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCHHHCE
FYYLRPPKADGSLPTNWESKFGGPAWAPFGDTGLYYLHLYDPTQADLDWHNPAVRQACAA
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
VVNFWRQKGVQGFRFDVINVTGKAEKLVDAPKGVPSKTLYTDTPVVHDYLKELNAASFGQ
HHHHHHHCCCCCEEEEEEEECCCHHHHHCCCCCCCCCCEECCCHHHHHHHHHHCHHHCCC
DVNSVTVGEMSSTTVANSVGYTNPANHELSMVFNFHHLKTDYVDGRKWSRMAFDFPRLKQ
CCCCEEECCCCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHCCCHHHHH
LLDSWASGMAAGGGWQALFWNNHDQPRALNRFGDAGRYRVKSAEMLATVIHLLRGTPFIY
HHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEE
MGEELGMTDPDYDNMADYVDIEALNAYRALIRSGYSHHDAFTIVKTKARDNSRTPMQWDD
ECHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCC
SAKAGFTTGKPWLTPTNQATINVAHELASGEIFDYYQRLIKLRKTMPIVADGGYQSWRLD
CCCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
DPQVFGYWRTYRQQKLLVLNNFYGQSTTVTLPEEMVGAQVLLSNYQDVNVTAQLTMQPYQ
CCHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEECHHH
AVALLLG
HHHHHCC
>Mature Secondary Structure
MKLSEQVIYQIYPKSFYDSNGDGVGDLRGVIEKIDYLKKLNIDMIWFNPFFVSPQNDNGY
CCCHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCC
DIADYYHIDPMFGTMADFEELVAKLKANGIGVMLDMVLNHTSTEHEWFQKALAGDEKYQK
EEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCHHHCE
FYYLRPPKADGSLPTNWESKFGGPAWAPFGDTGLYYLHLYDPTQADLDWHNPAVRQACAA
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
VVNFWRQKGVQGFRFDVINVTGKAEKLVDAPKGVPSKTLYTDTPVVHDYLKELNAASFGQ
HHHHHHHCCCCCEEEEEEEECCCHHHHHCCCCCCCCCCEECCCHHHHHHHHHHCHHHCCC
DVNSVTVGEMSSTTVANSVGYTNPANHELSMVFNFHHLKTDYVDGRKWSRMAFDFPRLKQ
CCCCEEECCCCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHCCCHHHHH
LLDSWASGMAAGGGWQALFWNNHDQPRALNRFGDAGRYRVKSAEMLATVIHLLRGTPFIY
HHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEE
MGEELGMTDPDYDNMADYVDIEALNAYRALIRSGYSHHDAFTIVKTKARDNSRTPMQWDD
ECHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCC
SAKAGFTTGKPWLTPTNQATINVAHELASGEIFDYYQRLIKLRKTMPIVADGGYQSWRLD
CCCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
DPQVFGYWRTYRQQKLLVLNNFYGQSTTVTLPEEMVGAQVLLSNYQDVNVTAQLTMQPYQ
CCHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEECHHH
AVALLLG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]