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The map label for this gene is oppA [H]

Identifier: 28376990

GI number: 28376990

Start: 19153

End: 20769

Strand: Direct

Name: oppA [H]

Synonym: lp_0018

Alternate gene names: 28376990

Gene position: 19153-20769 (Clockwise)

Preceding gene: 28376989

Following gene: 28376992

Centisome position: 0.58

GC content: 44.84

Gene sequence:

>1617_bases
ATGAAAAAAAGAATATGGATCAGCAGTATTGCTATTGTAGCCCTAGGATTAGTGTTAACTGGCTGCGGTAGCCAGCAGAG
TAGTCAGCAGAAGACGTTGAACGTAACGGCGACCCAGTCGATTGCGACCGCTGATCCTAATAAGGCCGACGATATCGCTA
GTCAGGCCGCTATTGCTCAGTTTATGGAAGGCTTGTACACAACTAATCAAAAGGGGAAAGTCGTGCCGGCAATTGCCAAG
AAAGTCGTCAAACCGACTAATAATGGGAAGACTTATACCTTTAATTTGCGGCACAATGCCAAGTGGTCGAATGGAAAAAA
GGTCACGGCCGCTGACTTTGTTTATTCCGTGCAACGCCAGGTCGATCCGAATACCAAGTCACAGGAAGTCGGACACGTTG
CTGAAATCAAGAATGCAACGGCAATCACGGCTGGTAAGAAGGCGGTGAAGACCTTAGGCGTTAAAGCGTTGGGTAAGTAT
AAGTTACAAATTACATTGCAACAGCGCGTGCCGTATTTTAATTATCGGCTAGCCACAGAGATCTATCCGTTAAACAAACA
ATTTACTGAGAAATACGGGAATAAGTATGGGACATCGGCACAGCGAACGCTCTCTAATGGTCCCTATGTCTTGAAGAGTT
GGAATGGGACGAATGACACGTGGAAATATGTGAAGAACCCGTATTATTATGACCGTAAACAGGTCCGAATCAAGAATATT
AAGGTGCAGACGGTCAAAAATAACAGTACGGCCGAGAACCTCTTCCAAAGCAATGAGGTCCAAGTCACCCAGATTACGGG
CACCCAAGTATCGGCAGCTGAGCAAGGGTCACTAAAAAGTCAGATGAAGGTTACGAAGTTAAATCAACTCTACTTCATGT
TGTGGAACCAGAAGCGCTCAGCATTGCAGAATACTGACTTGCGGCGTGCTGTGAGTTACGCTTTGAATCGCCAGTCATTG
GTTAAGAACGTTCTCAAAGACGGCTCAGTAGCGGCGACGTCATTAGTTCCTGCTGGCAATACCAAGAACCCGACAACAGG
GAAAGATTTTAATACGGATACCGGAAATTTGTATCCATACAGTCCAGCAAAGGCTAAACAGTATTGGCAGAAGGCTCAGG
CGAGCTTAGGAAAGCAAAAGTTAACACTGCAATTATTGACGAACGATAATGATATTAATAAGTCGGTGGCAGAATATATT
CAAGCTGCAATTGAGAAAAATCTTAGTGGTGTCACGGTCAATGTCAAGTCAGTACCACTGACAAATGAGATTTCAACTTT
AAGCAAGGGTGATTTTGACTTTGCCACGTTGTCGTGGTCGAGTGATTTCCAAGATCCAGTTGATTTCTTGAATAAGGCTT
CGATAACTAATTCTGTCAACTTTGGGAAGTTTAACAATGCGAAATATGAGCAATTAATCTCAACGATTACGGCCGATAAG
CAGTCAACTAAGGCCCGATATCAGACGATGCAGCAAGCGGCTAAGCTAGTCGCTCAGCAACAGGGGGTCACACCGATTTA
TCAAACTGCTGCTGCTCACTTGATCAGTAACAAGGTTGGTGGGGTTCACTTCACATTGTTGCGAGACGCCCTTTATCGCT
ATGCCTACTGGAAGTAA

Upstream 100 bases:

>100_bases
CACGGATAACGGAGGCTTACCGTTGATGTGTTGTTGTCGGCGCCAATCGAAGTATCGTTGCCAGTAACCGACATCATCGT
TAAGTTAGGAGTCATCATTC

Downstream 100 bases:

>100_bases
TCAGTCAGATAAATATTATTAATTTGATAGAAATGTAATTGAATAAATCAACTAGCCCGAAAAACGCGTTTTTTCGGGCT
TTTTTTGATGTTTTGGCAAA

Product: lipoprotein precursor, peptide binding protein OppA-like protein

Products: NA

Alternate protein names: Stage 0 sporulation protein KA [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MKKRIWISSIAIVALGLVLTGCGSQQSSQQKTLNVTATQSIATADPNKADDIASQAAIAQFMEGLYTTNQKGKVVPAIAK
KVVKPTNNGKTYTFNLRHNAKWSNGKKVTAADFVYSVQRQVDPNTKSQEVGHVAEIKNATAITAGKKAVKTLGVKALGKY
KLQITLQQRVPYFNYRLATEIYPLNKQFTEKYGNKYGTSAQRTLSNGPYVLKSWNGTNDTWKYVKNPYYYDRKQVRIKNI
KVQTVKNNSTAENLFQSNEVQVTQITGTQVSAAEQGSLKSQMKVTKLNQLYFMLWNQKRSALQNTDLRRAVSYALNRQSL
VKNVLKDGSVAATSLVPAGNTKNPTTGKDFNTDTGNLYPYSPAKAKQYWQKAQASLGKQKLTLQLLTNDNDINKSVAEYI
QAAIEKNLSGVTVNVKSVPLTNEISTLSKGDFDFATLSWSSDFQDPVDFLNKASITNSVNFGKFNNAKYEQLISTITADK
QSTKARYQTMQQAAKLVAQQQGVTPIYQTAAAHLISNKVGGVHFTLLRDALYRYAYWK

Sequences:

>Translated_538_residues
MKKRIWISSIAIVALGLVLTGCGSQQSSQQKTLNVTATQSIATADPNKADDIASQAAIAQFMEGLYTTNQKGKVVPAIAK
KVVKPTNNGKTYTFNLRHNAKWSNGKKVTAADFVYSVQRQVDPNTKSQEVGHVAEIKNATAITAGKKAVKTLGVKALGKY
KLQITLQQRVPYFNYRLATEIYPLNKQFTEKYGNKYGTSAQRTLSNGPYVLKSWNGTNDTWKYVKNPYYYDRKQVRIKNI
KVQTVKNNSTAENLFQSNEVQVTQITGTQVSAAEQGSLKSQMKVTKLNQLYFMLWNQKRSALQNTDLRRAVSYALNRQSL
VKNVLKDGSVAATSLVPAGNTKNPTTGKDFNTDTGNLYPYSPAKAKQYWQKAQASLGKQKLTLQLLTNDNDINKSVAEYI
QAAIEKNLSGVTVNVKSVPLTNEISTLSKGDFDFATLSWSSDFQDPVDFLNKASITNSVNFGKFNNAKYEQLISTITADK
QSTKARYQTMQQAAKLVAQQQGVTPIYQTAAAHLISNKVGGVHFTLLRDALYRYAYWK
>Mature_538_residues
MKKRIWISSIAIVALGLVLTGCGSQQSSQQKTLNVTATQSIATADPNKADDIASQAAIAQFMEGLYTTNQKGKVVPAIAK
KVVKPTNNGKTYTFNLRHNAKWSNGKKVTAADFVYSVQRQVDPNTKSQEVGHVAEIKNATAITAGKKAVKTLGVKALGKY
KLQITLQQRVPYFNYRLATEIYPLNKQFTEKYGNKYGTSAQRTLSNGPYVLKSWNGTNDTWKYVKNPYYYDRKQVRIKNI
KVQTVKNNSTAENLFQSNEVQVTQITGTQVSAAEQGSLKSQMKVTKLNQLYFMLWNQKRSALQNTDLRRAVSYALNRQSL
VKNVLKDGSVAATSLVPAGNTKNPTTGKDFNTDTGNLYPYSPAKAKQYWQKAQASLGKQKLTLQLLTNDNDINKSVAEYI
QAAIEKNLSGVTVNVKSVPLTNEISTLSKGDFDFATLSWSSDFQDPVDFLNKASITNSVNFGKFNNAKYEQLISTITADK
QSTKARYQTMQQAAKLVAQQQGVTPIYQTAAAHLISNKVGGVHFTLLRDALYRYAYWK

Specific function: This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=532, Percent_Identity=28.0075187969925, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87081878, Length=543, Percent_Identity=27.8084714548803, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787495, Length=508, Percent_Identity=26.9685039370079, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787762, Length=461, Percent_Identity=24.5119305856833, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1787052, Length=366, Percent_Identity=25.9562841530055, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789966, Length=558, Percent_Identity=23.4767025089606, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789887, Length=425, Percent_Identity=23.2941176470588, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59728; Mature: 59728

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRIWISSIAIVALGLVLTGCGSQQSSQQKTLNVTATQSIATADPNKADDIASQAAIAQ
CCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHH
FMEGLYTTNQKGKVVPAIAKKVVKPTNNGKTYTFNLRHNAKWSNGKKVTAADFVYSVQRQ
HHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEHHHHHHHHHHH
VDPNTKSQEVGHVAEIKNATAITAGKKAVKTLGVKALGKYKLQITLQQRVPYFNYRLATE
CCCCCCHHHCCHHHHHCCCCEECCCHHHHHHHHHHHCCCEEEEEEEHHCCCEEEEEEEEE
IYPLNKQFTEKYGNKYGTSAQRTLSNGPYVLKSWNGTNDTWKYVKNPYYYDRKQVRIKNI
EECCCHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHHCCCEEECCCEEEEEEE
KVQTVKNNSTAENLFQSNEVQVTQITGTQVSAAEQGSLKSQMKVTKLNQLYFMLWNQKRS
EEEEECCCCHHHHHHCCCCEEEEEECCCEECCHHHCCHHHHHHHHHHHHHHEEEEHHHHH
ALQNTDLRRAVSYALNRQSLVKNVLKDGSVAATSLVPAGNTKNPTTGKDFNTDTGNLYPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
SPAKAKQYWQKAQASLGKQKLTLQLLTNDNDINKSVAEYIQAAIEKNLSGVTVNVKSVPL
CCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
TNEISTLSKGDFDFATLSWSSDFQDPVDFLNKASITNSVNFGKFNNAKYEQLISTITADK
CHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
QSTKARYQTMQQAAKLVAQQQGVTPIYQTAAAHLISNKVGGVHFTLLRDALYRYAYWK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKRIWISSIAIVALGLVLTGCGSQQSSQQKTLNVTATQSIATADPNKADDIASQAAIAQ
CCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHH
FMEGLYTTNQKGKVVPAIAKKVVKPTNNGKTYTFNLRHNAKWSNGKKVTAADFVYSVQRQ
HHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEHHHHHHHHHHH
VDPNTKSQEVGHVAEIKNATAITAGKKAVKTLGVKALGKYKLQITLQQRVPYFNYRLATE
CCCCCCHHHCCHHHHHCCCCEECCCHHHHHHHHHHHCCCEEEEEEEHHCCCEEEEEEEEE
IYPLNKQFTEKYGNKYGTSAQRTLSNGPYVLKSWNGTNDTWKYVKNPYYYDRKQVRIKNI
EECCCHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHHCCCEEECCCEEEEEEE
KVQTVKNNSTAENLFQSNEVQVTQITGTQVSAAEQGSLKSQMKVTKLNQLYFMLWNQKRS
EEEEECCCCHHHHHHCCCCEEEEEECCCEECCHHHCCHHHHHHHHHHHHHHEEEEHHHHH
ALQNTDLRRAVSYALNRQSLVKNVLKDGSVAATSLVPAGNTKNPTTGKDFNTDTGNLYPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
SPAKAKQYWQKAQASLGKQKLTLQLLTNDNDINKSVAEYIQAAIEKNLSGVTVNVKSVPL
CCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
TNEISTLSKGDFDFATLSWSSDFQDPVDFLNKASITNSVNFGKFNNAKYEQLISTITADK
CHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
QSTKARYQTMQQAAKLVAQQQGVTPIYQTAAAHLISNKVGGVHFTLLRDALYRYAYWK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1901616; 1899858; 9384377 [H]