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The map label for this gene is lytT [H]

Identifier: 28211604

GI number: 28211604

Start: 2105016

End: 2105783

Strand: Direct

Name: lytT [H]

Synonym: CTC01979

Alternate gene names: 28211604

Gene position: 2105016-2105783 (Clockwise)

Preceding gene: 28211603

Following gene: 28211605

Centisome position: 75.2

GC content: 25.26

Gene sequence:

>768_bases
ATGAACAAAATAAATTGTGTAATAATAGAAGATGAAATTCCTTCTGCAGATGAATTAAATTATATGCTTAAAAACTATAA
CTTTATTAATATAGTAGGCATAGCACATGATGGAATAAAAGGACTAGAACTTATAAAAAACTTAAATCCTCATGGAGTAT
TTTTAGATATAAGTATGCCTTCTAAAAATGGCATGGAATTAGCTAAAGAAATAAAAACTTGGAATGAAAATATAGAAATA
ATATTTATTACTGCCTATGATAAATATGCCTTAAAAGCCTTTGAGATACATGCACTAGATTATATTTTAAAACCCTTTGA
AGAAGAGAGAATAAATATGGCAGTAAATAGACTATTAGAAATAGTAGAGCAAAAAAAGTCTGATGAAGATATTCCAAAAA
TTTTAGATAAGTTATTAGACAAATTACATTCAGAGGAAAATTTAATAGAAAAGATTCCATGTGAGCACTATGGAAAAATA
ATATTAGTTCCTCTCTCCCAAATTTATTTTTGCTATACAGAAAAAGATAAAGTATATGTTAAAACCTATAACAAAGAATA
TATAAGTAATTATACTTTAAACAAATTACAGAAAAAAACTAAGTTTTTCCGAGCCCACAGAAGCTATTTAGTAAATTTAA
ATAACATAAAAGAACTATTCTCTTGGTTTAATGGCACTTACAAATTAGTAATGAAGGATGATAAAAATACAGAAATTCCA
ATTAGCAGAGGAAATGTTAAACACTTAAAGGACATATTAGATTTTTAA

Upstream 100 bases:

>100_bases
GGCTAAAACTTCTCTTCGGAGAAGACTATAAAATAAATATAAAAAGCAACCCTAATAAAGGTACTTCTATATCTTTTTCA
ATACCTAAGGAGATGAATTT

Downstream 100 bases:

>100_bases
ATATATCGGATTTAGATTTTATATAGAATTGCTCTAGGAAATTGTGGAATTATCAAGCTTGAAGATTCCTAATTTTACTT
GTTAATAGAATAACTTTTAT

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNKINCVIIEDEIPSADELNYMLKNYNFINIVGIAHDGIKGLELIKNLNPHGVFLDISMPSKNGMELAKEIKTWNENIEI
IFITAYDKYALKAFEIHALDYILKPFEEERINMAVNRLLEIVEQKKSDEDIPKILDKLLDKLHSEENLIEKIPCEHYGKI
ILVPLSQIYFCYTEKDKVYVKTYNKEYISNYTLNKLQKKTKFFRAHRSYLVNLNNIKELFSWFNGTYKLVMKDDKNTEIP
ISRGNVKHLKDILDF

Sequences:

>Translated_255_residues
MNKINCVIIEDEIPSADELNYMLKNYNFINIVGIAHDGIKGLELIKNLNPHGVFLDISMPSKNGMELAKEIKTWNENIEI
IFITAYDKYALKAFEIHALDYILKPFEEERINMAVNRLLEIVEQKKSDEDIPKILDKLLDKLHSEENLIEKIPCEHYGKI
ILVPLSQIYFCYTEKDKVYVKTYNKEYISNYTLNKLQKKTKFFRAHRSYLVNLNNIKELFSWFNGTYKLVMKDDKNTEIP
ISRGNVKHLKDILDF
>Mature_255_residues
MNKINCVIIEDEIPSADELNYMLKNYNFINIVGIAHDGIKGLELIKNLNPHGVFLDISMPSKNGMELAKEIKTWNENIEI
IFITAYDKYALKAFEIHALDYILKPFEEERINMAVNRLLEIVEQKKSDEDIPKILDKLLDKLHSEENLIEKIPCEHYGKI
ILVPLSQIYFCYTEKDKVYVKTYNKEYISNYTLNKLQKKTKFFRAHRSYLVNLNNIKELFSWFNGTYKLVMKDDKNTEIP
ISRGNVKHLKDILDF

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=253, Percent_Identity=32.4110671936759, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI87082052, Length=253, Percent_Identity=31.6205533596838, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=29.0076335877863, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30016; Mature: 30016

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKINCVIIEDEIPSADELNYMLKNYNFINIVGIAHDGIKGLELIKNLNPHGVFLDISMP
CCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEEEECC
SKNGMELAKEIKTWNENIEIIFITAYDKYALKAFEIHALDYILKPFEEERINMAVNRLLE
CCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IVEQKKSDEDIPKILDKLLDKLHSEENLIEKIPCEHYGKIILVPLSQIYFCYTEKDKVYV
HHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHCCCEEEEECCCEEEEEECCCEEEE
KTYNKEYISNYTLNKLQKKTKFFRAHRSYLVNLNNIKELFSWFNGTYKLVMKDDKNTEIP
EECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCEEEEEEECCCCCCCC
ISRGNVKHLKDILDF
CCCCCHHHHHHHHCC
>Mature Secondary Structure
MNKINCVIIEDEIPSADELNYMLKNYNFINIVGIAHDGIKGLELIKNLNPHGVFLDISMP
CCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEEEECC
SKNGMELAKEIKTWNENIEIIFITAYDKYALKAFEIHALDYILKPFEEERINMAVNRLLE
CCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IVEQKKSDEDIPKILDKLLDKLHSEENLIEKIPCEHYGKIILVPLSQIYFCYTEKDKVYV
HHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHCCCEEEEECCCEEEEEECCCEEEE
KTYNKEYISNYTLNKLQKKTKFFRAHRSYLVNLNNIKELFSWFNGTYKLVMKDDKNTEIP
EECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCEEEEEEECCCCCCCC
ISRGNVKHLKDILDF
CCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]