Click here to switch to the map view.

The map label for this gene is lytC [H]

Identifier: 28211605

GI number: 28211605

Start: 2106159

End: 2108327

Strand: Direct

Name: lytC [H]

Synonym: CTC01980

Alternate gene names: 28211605

Gene position: 2106159-2108327 (Clockwise)

Preceding gene: 28211604

Following gene: 28211606

Centisome position: 75.24

GC content: 28.77

Gene sequence:

>2169_bases
ATGAAAAAACTTAATAAAGCCCTTTCTTCTACTGCTTTAGCAACTATAATTGCTACTACAAATTTAACTATGGTTCAAGC
TAAAGTAGATAACAGATTGGGAGGAAAAAACCGCTATGAAACTGCTAGGTTTATAGCTGAAAAATATTCAAAAGGTTCCG
TGGATAAAGTAATTTTAGCTAGTGGTAAAGGTCCTTTTGATGCTTTGGTGTCAAGTTTATTATCCAAAAAATTAAATGCA
CCTATACTTTTAGTAGGAGGTAGTGCTGACCAATACAAAGATGCTTTCAATTATATGGACAAGCATTTGAGTAAATCTGG
TACTGTTTATTTTCTTGGCGGAGAGGCATCTGTAAACAAAGATGTTGAAGCTCATGTAAAAAAATCAGGTTTTAAATTTA
AAAGATTAAGTGGCAAGGACAGATTTGAAACAAATAATAGTGTTTTAAATGAAATAAATGTTTCAAAGGGCACTCCTGTT
TTCTTAGTTAATGGATATGGCTTTGCAGATTCTTTAAGTGTTTCTAGTATATCTGCTATAAAAGACTATCCTGTTATAAT
GACAACTAAGGATACTATACCAAGTAATCTAAAAGCTCAATTAACTAAATTACAACCATCAAAAGTATACATCATAGGAT
CAGAGAATATAGTTTCTCAAAAAGTACAAGAGGAATTATATAAAATAAACAAAAATTTAAAAATGGATGATGTTGTTAGA
ATATATGGCAAGGATAGATTTGAAACAAATATTCTTATAAATAAAGCCTTTAATGTAAAATCTAACAATGCATTTGTAGC
ATCTGGTATGGATTTTGCTGACGCTCTATCTGGAAGTGCCCTTGCAGGTAAGTATAACGCTCCTATAGTACTTACTAATA
ATAAGAACTTCCAAAATGAAAAGGACTATTTAGCATCTACAGACTATAAAAACTTTTTCATACTTGGACTAGAAGGATCT
GTAAATAAATCTATAGAAAGTACATTAAATTCAGTTAAAGAACCTTCAAAAGCTGCTGGTGAATTTATGGATAAATTATC
AAAGGCTGAAGAAATAAAAAGTTGTGCAACTCAGTCTGACGTTACTATAAAATTTACTTCTAAAAATCTTCCTAGTGATA
TTCAAACAGGCTTTAATGCTTTCACTAAAGAAATAGGAGATACTATAACTTTAAAAACCACTGGTAAATTAGAAGCTGAT
TCAAAAGATAAAGCTAAACAAGAATTTACAGCTACTCTAAAATTAGGTGGAACAATGAAGGATAAAGATTTATCTTTCCC
TATGTGGGCTGAAGTCGATACTTCAAATAAAGTGAAACCAGATATGAAAGTAACCTATGGTATACCAAAGGATTTACTTA
AAAATGTAGAAGATGCATCCTTTGATCAACTAAAAAATAAAGATTATATAACTTTAGATCTATCCAATATGTCTCTGCCT
GGTGAAGATGGTAAAACAGGATTTAAAATGGATTCAAGTAAATTAGTATCTTTCTTAAAAGATAATGAAAAGCTTATGGA
AAAGATATCTCTTAGATTTGCTGCTGAATTTAATCCTAATTTGGATGTAGTTAAAAATGAAGGTGCTGTTACTTTAAAAG
ATGGAAGAAAAGCAACTTGTTACTCAATAGCTTTAAATAATGAAAGTTTAAGTACTCTTTTAAGATATGGTGGAAATAAC
GTATTAAATTTACTTCAAGATAAAGAAGTGGTAACTTTCCTTAAATCCTATATGAATATATATATGGAATCTATGAACTT
TGAAGGATTAAATAAAGATGAAATGTTGGAAATAAAAAAAGAAATGGAAGCTAGTATAGATAATTTATTAAATAATGGAC
CTAAGAGTTCTTTAACTATGCACCAAATAATAGATGGGTTTAAATCTTTAAATCTGTTAGGTAATGATGGTATAAAAATG
AAGTTCTACCTAGATAACAGAAATATTCCTATATCTTCTGAAGGAAGTATAGATATAAATGTTAACTTCAAAAACTTTAT
ACCTACTGCTAAGGGAGAAGTTGGAATGAAAATAGACTTTAAAAATTCTATATCCAATATAAATGATGATAGTATAAAAG
TATCTTTACCAAATACAAATAAAGACAATTCATTAGACTATTTTCAATTTCTTAATAACCTTTTAATGCCATTAGAAGAA
ACTAAATAA

Upstream 100 bases:

>100_bases
CTTAAATTCTTCATAAACCCCTTGTCATATAGGTGTCAATATATAATAATTAAGTTATAATGTATTATTTATTAATTTTT
GGTAAAGGAGAGGTTCTACA

Downstream 100 bases:

>100_bases
ACTATAACTTAACAAATAAATCCTGTGAGAAATTATCATGGGATTTATTTATTTTATAAAATAGTCTATAATATATAATA
TATTGTAAGCCTATTTATAA

Product: hypothetical protein

Products: NA

Alternate protein names: Cell wall hydrolase; Cell wall-associated polypeptide CWBP49; CWBP49; Major autolysin [H]

Number of amino acids: Translated: 722; Mature: 722

Protein sequence:

>722_residues
MKKLNKALSSTALATIIATTNLTMVQAKVDNRLGGKNRYETARFIAEKYSKGSVDKVILASGKGPFDALVSSLLSKKLNA
PILLVGGSADQYKDAFNYMDKHLSKSGTVYFLGGEASVNKDVEAHVKKSGFKFKRLSGKDRFETNNSVLNEINVSKGTPV
FLVNGYGFADSLSVSSISAIKDYPVIMTTKDTIPSNLKAQLTKLQPSKVYIIGSENIVSQKVQEELYKINKNLKMDDVVR
IYGKDRFETNILINKAFNVKSNNAFVASGMDFADALSGSALAGKYNAPIVLTNNKNFQNEKDYLASTDYKNFFILGLEGS
VNKSIESTLNSVKEPSKAAGEFMDKLSKAEEIKSCATQSDVTIKFTSKNLPSDIQTGFNAFTKEIGDTITLKTTGKLEAD
SKDKAKQEFTATLKLGGTMKDKDLSFPMWAEVDTSNKVKPDMKVTYGIPKDLLKNVEDASFDQLKNKDYITLDLSNMSLP
GEDGKTGFKMDSSKLVSFLKDNEKLMEKISLRFAAEFNPNLDVVKNEGAVTLKDGRKATCYSIALNNESLSTLLRYGGNN
VLNLLQDKEVVTFLKSYMNIYMESMNFEGLNKDEMLEIKKEMEASIDNLLNNGPKSSLTMHQIIDGFKSLNLLGNDGIKM
KFYLDNRNIPISSEGSIDINVNFKNFIPTAKGEVGMKIDFKNSISNINDDSIKVSLPNTNKDNSLDYFQFLNNLLMPLEE
TK

Sequences:

>Translated_722_residues
MKKLNKALSSTALATIIATTNLTMVQAKVDNRLGGKNRYETARFIAEKYSKGSVDKVILASGKGPFDALVSSLLSKKLNA
PILLVGGSADQYKDAFNYMDKHLSKSGTVYFLGGEASVNKDVEAHVKKSGFKFKRLSGKDRFETNNSVLNEINVSKGTPV
FLVNGYGFADSLSVSSISAIKDYPVIMTTKDTIPSNLKAQLTKLQPSKVYIIGSENIVSQKVQEELYKINKNLKMDDVVR
IYGKDRFETNILINKAFNVKSNNAFVASGMDFADALSGSALAGKYNAPIVLTNNKNFQNEKDYLASTDYKNFFILGLEGS
VNKSIESTLNSVKEPSKAAGEFMDKLSKAEEIKSCATQSDVTIKFTSKNLPSDIQTGFNAFTKEIGDTITLKTTGKLEAD
SKDKAKQEFTATLKLGGTMKDKDLSFPMWAEVDTSNKVKPDMKVTYGIPKDLLKNVEDASFDQLKNKDYITLDLSNMSLP
GEDGKTGFKMDSSKLVSFLKDNEKLMEKISLRFAAEFNPNLDVVKNEGAVTLKDGRKATCYSIALNNESLSTLLRYGGNN
VLNLLQDKEVVTFLKSYMNIYMESMNFEGLNKDEMLEIKKEMEASIDNLLNNGPKSSLTMHQIIDGFKSLNLLGNDGIKM
KFYLDNRNIPISSEGSIDINVNFKNFIPTAKGEVGMKIDFKNSISNINDDSIKVSLPNTNKDNSLDYFQFLNNLLMPLEE
TK
>Mature_722_residues
MKKLNKALSSTALATIIATTNLTMVQAKVDNRLGGKNRYETARFIAEKYSKGSVDKVILASGKGPFDALVSSLLSKKLNA
PILLVGGSADQYKDAFNYMDKHLSKSGTVYFLGGEASVNKDVEAHVKKSGFKFKRLSGKDRFETNNSVLNEINVSKGTPV
FLVNGYGFADSLSVSSISAIKDYPVIMTTKDTIPSNLKAQLTKLQPSKVYIIGSENIVSQKVQEELYKINKNLKMDDVVR
IYGKDRFETNILINKAFNVKSNNAFVASGMDFADALSGSALAGKYNAPIVLTNNKNFQNEKDYLASTDYKNFFILGLEGS
VNKSIESTLNSVKEPSKAAGEFMDKLSKAEEIKSCATQSDVTIKFTSKNLPSDIQTGFNAFTKEIGDTITLKTTGKLEAD
SKDKAKQEFTATLKLGGTMKDKDLSFPMWAEVDTSNKVKPDMKVTYGIPKDLLKNVEDASFDQLKNKDYITLDLSNMSLP
GEDGKTGFKMDSSKLVSFLKDNEKLMEKISLRFAAEFNPNLDVVKNEGAVTLKDGRKATCYSIALNNESLSTLLRYGGNN
VLNLLQDKEVVTFLKSYMNIYMESMNFEGLNKDEMLEIKKEMEASIDNLLNNGPKSSLTMHQIIDGFKSLNLLGNDGIKM
KFYLDNRNIPISSEGSIDINVNFKNFIPTAKGEVGMKIDFKNSISNINDDSIKVSLPNTNKDNSLDYFQFLNNLLMPLEE
TK

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teich

COG id: COG2247

COG function: function code M; Putative cell wall-binding domain

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR002508 [H]

Pfam domain/function: PF01520 Amidase_3; PF04122 CW_binding_2 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 79871; Mature: 79871

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLNKALSSTALATIIATTNLTMVQAKVDNRLGGKNRYETARFIAEKYSKGSVDKVILA
CCHHHHHHHHHHHEEEEEECCEEEEEEEHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
SGKGPFDALVSSLLSKKLNAPILLVGGSADQYKDAFNYMDKHLSKSGTVYFLGGEASVNK
CCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
DVEAHVKKSGFKFKRLSGKDRFETNNSVLNEINVSKGTPVFLVNGYGFADSLSVSSISAI
CHHHHHHHCCCEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
KDYPVIMTTKDTIPSNLKAQLTKLQPSKVYIIGSENIVSQKVQEELYKINKNLKMDDVVR
CCCCEEEEECCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHE
IYGKDRFETNILINKAFNVKSNNAFVASGMDFADALSGSALAGKYNAPIVLTNNKNFQNE
EECCCCEEEEEEEEEEECCCCCCEEEECCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCC
KDYLASTDYKNFFILGLEGSVNKSIESTLNSVKEPSKAAGEFMDKLSKAEEIKSCATQSD
CCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
VTIKFTSKNLPSDIQTGFNAFTKEIGDTITLKTTGKLEADSKDKAKQEFTATLKLGGTMK
EEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHEEEEEECCCCC
DKDLSFPMWAEVDTSNKVKPDMKVTYGIPKDLLKNVEDASFDQLKNKDYITLDLSNMSLP
CCCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHCCCCCCHHHHCCCCEEEEEECCCCCC
GEDGKTGFKMDSSKLVSFLKDNEKLMEKISLRFAAEFNPNLDVVKNEGAVTLKDGRKATC
CCCCCCCCEECHHHHHHHHHCCHHHHHHHHHHEEEECCCCCEEEECCCEEEECCCCCEEE
YSIALNNESLSTLLRYGGNNVLNLLQDKEVVTFLKSYMNIYMESMNFEGLNKDEMLEIKK
EEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EMEASIDNLLNNGPKSSLTMHQIIDGFKSLNLLGNDGIKMKFYLDNRNIPISSEGSIDIN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCEEECCCCEEEEEEECCCCCCCCCCCCEEEE
VNFKNFIPTAKGEVGMKIDFKNSISNINDDSIKVSLPNTNKDNSLDYFQFLNNLLMPLEE
EEHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
TK
CC
>Mature Secondary Structure
MKKLNKALSSTALATIIATTNLTMVQAKVDNRLGGKNRYETARFIAEKYSKGSVDKVILA
CCHHHHHHHHHHHEEEEEECCEEEEEEEHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
SGKGPFDALVSSLLSKKLNAPILLVGGSADQYKDAFNYMDKHLSKSGTVYFLGGEASVNK
CCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
DVEAHVKKSGFKFKRLSGKDRFETNNSVLNEINVSKGTPVFLVNGYGFADSLSVSSISAI
CHHHHHHHCCCEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
KDYPVIMTTKDTIPSNLKAQLTKLQPSKVYIIGSENIVSQKVQEELYKINKNLKMDDVVR
CCCCEEEEECCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHE
IYGKDRFETNILINKAFNVKSNNAFVASGMDFADALSGSALAGKYNAPIVLTNNKNFQNE
EECCCCEEEEEEEEEEECCCCCCEEEECCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCC
KDYLASTDYKNFFILGLEGSVNKSIESTLNSVKEPSKAAGEFMDKLSKAEEIKSCATQSD
CCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
VTIKFTSKNLPSDIQTGFNAFTKEIGDTITLKTTGKLEADSKDKAKQEFTATLKLGGTMK
EEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHEEEEEECCCCC
DKDLSFPMWAEVDTSNKVKPDMKVTYGIPKDLLKNVEDASFDQLKNKDYITLDLSNMSLP
CCCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHCCCCCCHHHHCCCCEEEEEECCCCCC
GEDGKTGFKMDSSKLVSFLKDNEKLMEKISLRFAAEFNPNLDVVKNEGAVTLKDGRKATC
CCCCCCCCEECHHHHHHHHHCCHHHHHHHHHHEEEECCCCCEEEECCCEEEECCCCCEEE
YSIALNNESLSTLLRYGGNNVLNLLQDKEVVTFLKSYMNIYMESMNFEGLNKDEMLEIKK
EEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EMEASIDNLLNNGPKSSLTMHQIIDGFKSLNLLGNDGIKMKFYLDNRNIPISSEGSIDIN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCEEECCCCEEEEEEECCCCCCCCCCCCEEEE
VNFKNFIPTAKGEVGMKIDFKNSISNINDDSIKVSLPNTNKDNSLDYFQFLNNLLMPLEE
EEHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1357079; 1682302; 9384377 [H]