Click here to switch to the map view.

The map label for this gene is aroE [H]

Identifier: 28210815

GI number: 28210815

Start: 1185379

End: 1186149

Strand: Direct

Name: aroE [H]

Synonym: CTC01117

Alternate gene names: 28210815

Gene position: 1185379-1186149 (Clockwise)

Preceding gene: 28210814

Following gene: 28210816

Centisome position: 42.35

GC content: 23.99

Gene sequence:

>771_bases
ATGAAGTACACAGGATTATTAGGAAAAAATATATCTTACTCACAATCACCTAAGATTCATAATGAATATTATGAAAAAAA
CAATATTCCATTTAAATATAAAATATTTGATGTAAATGAAGATGAGCTATTTTACTTTATAGATACATTATACAGAAAAA
ACATAGTAGGATTTAATGTAACTATACCTTACAAAACTAAGATTTTAAAATATATAGAAAAGCTTGTATACCCAGCTGAT
AAAATAGGAGCAGTCAATACGGTTGTAGTGCTAAAAGACAAATTAATTGGATTTAATACTGATTACTATGGCTTTACTGA
AAGTCTAAAAAGAAGAAATGTTGAATTAAGAGATAAGAATGCATTAATTATAGGAAATGGCGGTTCAGCTCTTTGTGTTT
ATTATGCATTAATGGACATAGGGTGTAAAAATTTAGATGTTTTATGTAGAAATAAAGATAAAAACATAGAAAAATTGAAA
GAAATAAGATGTTTTTACGATTTTTATGATATTATAAAATATGAACAGTATGATATAATAATAAATTGTACTCCTTTGGG
AGGAAACAACTATATAAAAAATCTTCCAATAAATTTAGAAAAAATTAAATTAAAAAAAGATGTGATAATATACGATTTAA
ATTATAAGACACAAGATACTATTTTTATAAATCAGGCAAAAAGTATGAATATAATGGCAATTAATGGAGAAGATATGTTA
AGACTCCAGGCTTATAAGGCTATTGATATATGGGGAATATATATATATTAA

Upstream 100 bases:

>100_bases
CTATGCAAGGAAATGCAAAAACCATAAAGGCTTTGAATTAAGCTTAGATATGGTATAAAATATAGAGAGATTTTAAAACA
GTATAAAGTGAGGAAAACAT

Downstream 100 bases:

>100_bases
ACGGGGAGGATAAATAAAGTGGAAAGTTTAAGCAATTTGTTAGAAACAACATTACAACATAATGGTTCAGATTTACATCT
TACAGTAGGTGTAGCTCCAA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKYTGLLGKNISYSQSPKIHNEYYEKNNIPFKYKIFDVNEDELFYFIDTLYRKNIVGFNVTIPYKTKILKYIEKLVYPAD
KIGAVNTVVVLKDKLIGFNTDYYGFTESLKRRNVELRDKNALIIGNGGSALCVYYALMDIGCKNLDVLCRNKDKNIEKLK
EIRCFYDFYDIIKYEQYDIIINCTPLGGNNYIKNLPINLEKIKLKKDVIIYDLNYKTQDTIFINQAKSMNIMAINGEDML
RLQAYKAIDIWGIYIY

Sequences:

>Translated_256_residues
MKYTGLLGKNISYSQSPKIHNEYYEKNNIPFKYKIFDVNEDELFYFIDTLYRKNIVGFNVTIPYKTKILKYIEKLVYPAD
KIGAVNTVVVLKDKLIGFNTDYYGFTESLKRRNVELRDKNALIIGNGGSALCVYYALMDIGCKNLDVLCRNKDKNIEKLK
EIRCFYDFYDIIKYEQYDIIINCTPLGGNNYIKNLPINLEKIKLKKDVIIYDLNYKTQDTIFINQAKSMNIMAINGEDML
RLQAYKAIDIWGIYIY
>Mature_256_residues
MKYTGLLGKNISYSQSPKIHNEYYEKNNIPFKYKIFDVNEDELFYFIDTLYRKNIVGFNVTIPYKTKILKYIEKLVYPAD
KIGAVNTVVVLKDKLIGFNTDYYGFTESLKRRNVELRDKNALIIGNGGSALCVYYALMDIGCKNLDVLCRNKDKNIEKLK
EIRCFYDFYDIIKYEQYDIIINCTPLGGNNYIKNLPINLEKIKLKKDVIIYDLNYKTQDTIFINQAKSMNIMAINGEDML
RLQAYKAIDIWGIYIY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=266, Percent_Identity=24.0601503759398, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789675, Length=266, Percent_Identity=27.0676691729323, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=152, Percent_Identity=36.1842105263158, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30034; Mature: 30034

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTGLLGKNISYSQSPKIHNEYYEKNNIPFKYKIFDVNEDELFYFIDTLYRKNIVGFNV
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEHHHHCCEEEEEE
TIPYKTKILKYIEKLVYPADKIGAVNTVVVLKDKLIGFNTDYYGFTESLKRRNVELRDKN
EECHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHCCCEEECCC
ALIIGNGGSALCVYYALMDIGCKNLDVLCRNKDKNIEKLKEIRCFYDFYDIIKYEQYDII
EEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECEEEE
INCTPLGGNNYIKNLPINLEKIKLKKDVIIYDLNYKTQDTIFINQAKSMNIMAINGEDML
EEEEECCCCCCEEECCCCCEEEEEECCEEEEEECCCCCCEEEEECCCCEEEEEECCCCEE
RLQAYKAIDIWGIYIY
EEEEEEEEEEEEEEEC
>Mature Secondary Structure
MKYTGLLGKNISYSQSPKIHNEYYEKNNIPFKYKIFDVNEDELFYFIDTLYRKNIVGFNV
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEHHHHCCEEEEEE
TIPYKTKILKYIEKLVYPADKIGAVNTVVVLKDKLIGFNTDYYGFTESLKRRNVELRDKN
EECHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHCCCEEECCC
ALIIGNGGSALCVYYALMDIGCKNLDVLCRNKDKNIEKLKEIRCFYDFYDIIKYEQYDII
EEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECEEEE
INCTPLGGNNYIKNLPINLEKIKLKKDVIIYDLNYKTQDTIFINQAKSMNIMAINGEDML
EEEEECCCCCCEEECCCCCEEEEEECCEEEEEECCCCCCEEEEECCCCEEEEEECCCCEE
RLQAYKAIDIWGIYIY
EEEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA