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The map label for this gene is fur [H]

Identifier: 28210759

GI number: 28210759

Start: 1127635

End: 1128117

Strand: Direct

Name: fur [H]

Synonym: CTC01057

Alternate gene names: 28210759

Gene position: 1127635-1128117 (Clockwise)

Preceding gene: 28210758

Following gene: 28210760

Centisome position: 40.28

GC content: 28.99

Gene sequence:

>483_bases
ATGAAGAGAGGTATTTCCATGGTAGAGGTTTCTTATGATAAAGATAAAATGGAAAGAATCAAAGATATACTAAAAGAAAA
TGGATATAAATTAACTCCTCAGAGAAGAGCCATTGTTGGAATGATAATTAATAATAAGGGAAATCATTTAACTACGGAAG
AAATATACAACTTGGTTAAGGTGAATTGTCCGGAAATAGGTTTGGCAACTGTTTATAGAACTGTGCTTCTTTTAGAGGAA
ATTGGAATAGTAACAAGACTGGATTTAAATGATGGATGTAGCAGATATGAATTAGTTAGCGAAGATGAACATCATCAACA
TCACCATCTAATATGCATCAATTGTAGTAAAGTTCTTGAAGTAGAGGGAGATTTATTGGAAAATTTAGAAGAAAAAATAG
AAAAAAAATATGAATTTAAAATAGAAGATCATACCGTTAAATTTTATGGAATATGTAAGGATTGTTTAAAAAAGTCAAAG
TAA

Upstream 100 bases:

>100_bases
GACAAAAGCTATGCCATGGCATAGCTTTTGTTCTTAACTAAAAATTGACATAGATTTCTAGTTAAGGTTATAATGTTTTT
AATATTTTTAAAAAAATTCT

Downstream 100 bases:

>100_bases
TAGATTTATAAATATATAATCTTAAATTTGAAAAAGGAGGGAAAAAATGAAGAAAGAAAGAGACAAAGTAAAAGTCATAC
CCTTAGGTGGCTTAAATGAA

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKRGISMVEVSYDKDKMERIKDILKENGYKLTPQRRAIVGMIINNKGNHLTTEEIYNLVKVNCPEIGLATVYRTVLLLEE
IGIVTRLDLNDGCSRYELVSEDEHHQHHHLICINCSKVLEVEGDLLENLEEKIEKKYEFKIEDHTVKFYGICKDCLKKSK

Sequences:

>Translated_160_residues
MKRGISMVEVSYDKDKMERIKDILKENGYKLTPQRRAIVGMIINNKGNHLTTEEIYNLVKVNCPEIGLATVYRTVLLLEE
IGIVTRLDLNDGCSRYELVSEDEHHQHHHLICINCSKVLEVEGDLLENLEEKIEKKYEFKIEDHTVKFYGICKDCLKKSK
>Mature_160_residues
MKRGISMVEVSYDKDKMERIKDILKENGYKLTPQRRAIVGMIINNKGNHLTTEEIYNLVKVNCPEIGLATVYRTVLLLEE
IGIVTRLDLNDGCSRYELVSEDEHHQHHHLICINCSKVLEVEGDLLENLEEKIEKKYEFKIEDHTVKFYGICKDCLKKSK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=134, Percent_Identity=35.8208955223881, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18622; Mature: 18622

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGISMVEVSYDKDKMERIKDILKENGYKLTPQRRAIVGMIINNKGNHLTTEEIYNLVK
CCCCCEEEEEECCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCEECHHHHHHHHH
VNCPEIGLATVYRTVLLLEEIGIVTRLDLNDGCSRYELVSEDEHHQHHHLICINCSKVLE
CCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEECCCCCCCCCCCEEEEEECHHHHC
VEGDLLENLEEKIEKKYEFKIEDHTVKFYGICKDCLKKSK
CCHHHHHHHHHHHHHHHCEEECCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MKRGISMVEVSYDKDKMERIKDILKENGYKLTPQRRAIVGMIINNKGNHLTTEEIYNLVK
CCCCCEEEEEECCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCEECHHHHHHHHH
VNCPEIGLATVYRTVLLLEEIGIVTRLDLNDGCSRYELVSEDEHHQHHHLICINCSKVLE
CCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEECCCCCCCCCCCEEEEEECHHHHC
VEGDLLENLEEKIEKKYEFKIEDHTVKFYGICKDCLKKSK
CCHHHHHHHHHHHHHHHCEEECCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]